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84-61-7,MFCD00003849
Catalog No.:AA003PBB

84-61-7 | Dicyclohexyl phthalate

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25g
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100g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003PBB
Chemical Name:
Dicyclohexyl phthalate
CAS Number:
84-61-7
Molecular Formula:
C20H26O4
Molecular Weight:
330.4180
MDL Number:
MFCD00003849
SMILES:
O=C(c1ccccc1C(=O)OC1CCCCC1)OC1CCCCC1
NSC Number:
6101
UN Number:
3082
Properties
Properties
 
BP:
200-235 °C (4 mmHg)  
Form:
Solid  
MP:
63-67°C(lit.);  
Refractive Index:
1.485  
Solubility:
0.2mg/l  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
381  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
6  
XLogP3:
5.2  

Literature

Title: Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180201

Title: Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR.

Journal: Toxicology letters 20170805

Title: Inhibitory modulation of human estrogen receptor α and β activities by dicyclohexyl phthalate in human breast cancer cell lines.

Journal: The Journal of toxicological sciences 20170101

Title: Lethal and sublethal effects of phthalate diesters in Silurana tropicalis larvae.

Journal: Environmental toxicology and chemistry 20161001

Title: Cytochrome P450-inhibitory activity of parabens and phthalates used in consumer products.

Journal: The Journal of toxicological sciences 20160101

Title: Structure-dependent activity of phthalate esters and phthalate monoesters binding to human constitutive androstane receptor.

Journal: Chemical research in toxicology 20150615

Title: Assessment of estrogenic potential of diethyl phthalate in female reproductive system involving both genomic and non-genomic actions.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20141101

Title: Effect of cooking at home on the levels of eight phthalates in foods.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121201

Title: Phthalates dietary exposure and food sources for Belgian preschool children and adults.

Journal: Environment international 20121101

Title: Phthalates in Belgian cow's milk and the role of feed and other contamination pathways at farm level.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801

Title: Analysis of phthalates in food products and packaging materials sold on the Belgian market.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120701

Title: Biomarker genes for detecting estrogenic activity of endocrine disruptors via estrogen receptors.

Journal: International journal of environmental research and public health 20120301

Title: Easy synthesis of surface-tunable carbon-encapsulated magnetic nanoparticles: adsorbents for selective isolation and preconcentration of organic pollutants.

Journal: ACS applied materials & interfaces 20120101

Title: Determination of phthalic acid diesters in human milk at low ppb levels.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: A novel silver-coated solid-phase microextraction metal fiber based on electroless plating technique.

Journal: Analytica chimica acta 20110909

Title: Development of an ionic liquid-based dispersive liquid-liquid micro-extraction method for the determination of phthalate esters in water samples.

Journal: Journal of separation science 20110701

Title: Comparative assessment of human exposure to phthalate esters from house dust in China and the United States.

Journal: Environmental science & technology 20110415

Title: Enzymatic hydrolysis of structurally diverse phthalic acid esters by porcine and bovine pancreatic cholesterol esterases.

Journal: Chemosphere 20101201

Title: An indirect competitive fluorescence immunoassay for determination of dicyclohexyl phthalate in water samples.

Journal: Journal of fluorescence 20101101

Title: Poly(methacrylic acid-co-ethylene glycol dimethacrylate) monolith microextraction coupled with high performance liquid chromatography for the determination of phthalate esters in cosmetics.

Journal: Analytica chimica acta 20100831

Title: Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation.

Journal: Obesity (Silver Spring, Md.) 20100701

Title: Dietary intake is associated with phthalate body burden in a nationally representative sample.

Journal: Environmental health perspectives 20100701

Title: Preparation of a chitosan-coated C(18)-functionalized magnetite nanoparticle sorbent for extraction of phthalate ester compounds from environmental water samples.

Journal: Analytical and bioanalytical chemistry 20100501

Title: Determination of phthalates in fruit jellies by dispersive SPE coupled with HPLC-MS.

Journal: Journal of separation science 20100201

Title: Structure-dependent inhibition of human and rat 11beta-hydroxysteroid dehydrogenase 2 activities by phthalates.

Journal: Chemico-biological interactions 20100105

Title: Effects of in utero through lactational exposure to dicyclohexyl phthalate and p,p'-DDE in Sprague-Dawley rats.

Journal: Toxicology letters 20090825

Title: Differential developmental toxicities of di-n-hexyl phthalate and dicyclohexyl phthalate administered orally to rats.

Journal: Journal of applied toxicology : JAT 20090801

Title: Medications as a potential source of exposure to phthalates in the U.S. population.

Journal: Environmental health perspectives 20090201

Title: Screening method for phthalate esters in water using liquid-phase microextraction based on the solidification of a floating organic microdrop combined with gas chromatography-mass spectrometry.

Journal: Talanta 20080815

Title: Prenatal phenol and phthalate exposures and birth outcomes.

Journal: Environmental health perspectives 20080801

Title: Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling.

Journal: FEMS immunology and medical microbiology 20080301

Title: Phthalate levels in Norwegian indoor air related to particle size fraction.

Journal: Journal of environmental monitoring : JEM 20071201

Title: Development of dispersive liquid-liquid microextraction combined with gas chromatography-mass spectrometry as a simple, rapid and highly sensitive method for the determination of phthalate esters in water samples.

Journal: Journal of chromatography. A 20071123

Title: [Simultaneous determination of phthalates and parabens in cosmetic products by gas chromatography/mass spectrometry coupled with solid phase extraction].

Journal: Se pu = Chinese journal of chromatography 20070301

Title: Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods.

Journal: Journal of separation science 20070101

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Effects of possible endocrine disrupting chemicals on bacterial component-induced activation of NF-kappaB.

Journal: Biological & pharmaceutical bulletin 20061001

Title: [Study of dicyclohexyl phthalate on preparation and characterization of artificial antigen].

Journal: Wei sheng yan jiu = Journal of hygiene research 20060901

Title: [Determination of phthalic acid esters in textiles by solid phase extraction-gas chromatography].

Journal: Se pu = Chinese journal of chromatography 20060901

Title: Detection of thyroid system-disrupting chemicals using in vitro and in vivo screening assays in Xenopus laevis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051201

Title: Two-generation reproductive toxicity studies in rats with extra parameters for detecting endocrine disrupting activity: introductory overview of results for nine chemicals.

Journal: The Journal of toxicological sciences 20051201

Title: A two-generation reproductive toxicity study of dicyclohexyl phthalate in rats.

Journal: The Journal of toxicological sciences 20051201

Title: Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor.

Journal: Toxicology 20050601

Title: Simultaneous screening and determination eight phthalates in plastic products for food use by sonication-assisted extraction/GC-MS methods.

Journal: Talanta 20050430

Title: Conflict of estrogenic activity by various phthalates between in vitro and in vivo models related to the expression of Calbindin-D9k.

Journal: The Journal of reproduction and development 20050401

Title: Alteration of gene expression of G protein-coupled receptors in endocrine disruptors-caused hyperactive rats.

Journal: Regulatory peptides 20050315

Title: Inhibitory effects of some possible endocrine-disrupting chemicals on the isozymes of human 11beta-hydroxysteroid dehydrogenase and expression of their mRNA in gonads and adrenal glands.

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20050101

Title: Exposure to phthalate esters from indoor environment.

Journal: Journal of exposure analysis and environmental epidemiology 20041101

Title: Dicyclohexylphthalate causes hyperactivity in the rat concomitantly with impairment of tyrosine hydroxylase immunoreactivity.

Journal: Journal of neurochemistry 20041001

Title: Suppression by phthalates of the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma SH-SY5Y cells.

Journal: Toxicology 20040805

Title: Biodegradation of phthalate esters by two bacteria strains.

Journal: Chemosphere 20040401

Title: Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000.

Journal: Environmental health perspectives 20040301

Title: Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro.

Journal: Biological & pharmaceutical bulletin 20030801

Title: Effects and toxicity of phthalate esters to hemocytes of giant freshwater prawn, Macrobrachium rosenbergii.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20030619

Title: Estimated daily intake of plasticizers in 1-week duplicate diet samples following regulation of DEHP-containing PVC gloves in Japan.

Journal: Food additives and contaminants 20030401

Title: Occurrence and microbial degradation of phthalate esters in Taiwan river sediments.

Journal: Chemosphere 20021201

Title: [Contents of plasticizers in cap-sealing for bottled food and their migration into food].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021201

Title: Effect of phthalate esters and alkylphenols on steroidogenesis in human adrenocortical H295R cells.

Journal: Environmental toxicology and pharmacology 20010701

Title: Determination of phthalates in crude extracts of sewage sludges by high-resolution capillary gas chromatography with mass spectrometric detection.

Journal: Journal of AOAC International 20010101

Title: Effects of endocrine disrupting chemicals on the microtubule network in Chinese hamster V79 cells in culture and in Sertoli cells in rats.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20010101

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