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Title: Rational design of highly selective spleen tyrosine kinase inhibitors.
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Title: Discovery and development of spleen tyrosine kinase (SYK) inhibitors.
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Title: Comprehensive analysis of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111030
Title: Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures.
Journal: Protein science : a publication of the Protein Society 20110201
Title: Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry.
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Title: Structural insights for design of potent spleen tyrosine kinase inhibitors from crystallographic analysis of three inhibitor complexes.
Journal: Chemical biology & drug design 20090401
Title: Pharmacophore modeling study based on known spleen tyrosine kinase inhibitors together with virtual screening for identifying novel inhibitors.
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Title: Developmental toxicity associated with receptor tyrosine kinase Ret inhibition in reproductive toxicity testing.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20090201
Title: R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation.
Journal: The Journal of pharmacology and experimental therapeutics 20061201
