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842-07-9,MFCD00003911
Catalog No.:AA00ID9Y

842-07-9 | Sudan i

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25g
98% HPLC
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ID9Y
Chemical Name:
Sudan i
CAS Number:
842-07-9
Molecular Formula:
C16H12N2O
Molecular Weight:
248.2793
MDL Number:
MFCD00003911
SMILES:
Oc1ccc2c(c1/N=N/c1ccccc1)cccc2
Properties
Computed Properties
 
Complexity:
312  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
4.1  

Downstream Synthesis Route

[1]ChemischeBerichte,1900,vol.33,p.805

[2]ChemischeBerichte,1900,vol.33,p.805

[1]Hewitt;Auld[JournaloftheChemicalSociety,1902,vol.81,p.1206]

[2]Charrier;Ferreri[GazzettaChimicaItaliana,1914,vol.44I,p.176]

[1]Hewitt;Auld[JournaloftheChemicalSociety,1902,vol.81,p.1206]

[1]GazzettaChimicaItaliana,1912,vol.42II,p.123    GazzettaChimicaItaliana,1914,vol.44I,p.179

10534-89-1    842-07-9   
CASUnavailable 

[1][GmelinHandbuchderAnorganischenChemie,GmelinHandbook:Co:SVol.B2,172,page697-700]

[2]Bailar,J.C.;Callis,C.F.[JournaloftheAmericanChemicalSociety,1952,vol.74,p.6018-6021]

Literature

Title: Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo.

Journal: Toxicology 20160217

Title: Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.

Journal: International journal of molecular sciences 20150101

Title: Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions.

Journal: Toxicology 20140406

Title: Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I).

Journal: Chemical research in toxicology 20130218

Title: Solubilization of two organic dyes by cationic ester-containing gemini surfactants.

Journal: Journal of colloid and interface science 20120615

Title: Selective solid-phase extraction of Sudan I in chilli sauce by single-hole hollow molecularly imprinted polymers.

Journal: Journal of agricultural and food chemistry 20120111

Title: Molecularly imprinted polymer coated solid-phase microextraction fibers for determination of Sudan I-IV dyes in hot chili powder and poultry feed samples.

Journal: Journal of chromatography. A 20120106

Title: Molecularly imprinted microspheres as SPE sorbent for selective extraction of four Sudan dyes in catsup products.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111001

Title: Molecularly imprinted solid-phase extraction combined with ultrasound-assisted dispersive liquid-liquid microextraction for the determination of four Sudan dyes in sausage samples.

Journal: The Analyst 20110621

Title: Rational design and application of molecularly imprinted sol-gel polymer for the electrochemically selective and sensitive determination of Sudan I.

Journal: Talanta 20110415

Title: A monoclonal antibody-based immunosensor for detection of Sudan I using electrochemical impedance spectroscopy.

Journal: Talanta 20110315

Title: Metabolic influences for mutation induction curves after exposure to Sudan-1 and para red.

Journal: Mutagenesis 20100701

Title: Quantification of (15)N-nitrate in urine with gas chromatography combustion isotope ratio mass spectrometry to estimate endogenous NO production.

Journal: Analytical chemistry 20100115

Title: Determination of para red, Sudan dyes, canthaxanthin, and astaxanthin in animal feeds using UPLC.

Journal: Journal of chromatographic science 20100101

Title: Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

Journal: Journal of chromatographic science 20100101

Title: [Selection of the optimal method of extraction and determination of dye Sudan I-IV and Para Red by high-performance liquid chromatography].

Journal: Voprosy pitaniia 20100101

Title: Rapid determination of banned Sudan I in foodstuffs using a mesoporous SiO2 modified electrode.

Journal: Journal of AOAC International 20100101

Title: Mechanism of formation of (deoxy)guanosine adducts derived from peroxidase-catalyzed oxidation of the carcinogenic nonaminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I).

Journal: Chemical research in toxicology 20091101

Title: Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study.

Journal: Interdisciplinary toxicology 20090901

Title: Determining the adulteration of spices with Sudan I-II-II-IV dyes by UV-visible spectroscopy and multivariate classification techniques.

Journal: Talanta 20090815

Title: Preparation of a biologically active apo-cytochrome b5 via heterologous expression in Escherichia coli.

Journal: Protein expression and purification 20090801

Title: Development of enzyme-linked immunosorbent assays for Sudan dyes in chilli powder, ketchup and egg yolk.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090601

Title: Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole.

Journal: Interdisciplinary toxicology 20081201

Title: A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase.

Journal: Neuro endocrinology letters 20081001

Title: Experimental approaches to evaluate activities of cytochromes P450 3A.

Journal: Interdisciplinary toxicology 20080901

Title: Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2.

Journal: Interdisciplinary toxicology 20080901

Title: [Synthesis of Sudan I artificial antigen].

Journal: Wei sheng yan jiu = Journal of hygiene research 20080501

Title: Inhibition of Sudan I genotoxicity in human liver-derived HepG2 cells by the antioxidant hydroxytyrosol.

Journal: Free radical research 20080201

Title: Assay of the set of all Sudan azodye (I, II, III, IV, and Para-Red) contaminating agents by liquid chromatography-tandem mass spectrometry and isotope dilution methodology.

Journal: Journal of agricultural and food chemistry 20080109

Title: The induction of cytochrome P450 1A1 by sudan dyes.

Journal: Journal of biochemical and molecular toxicology 20080101

Title: A simple 2-directional high-performance thin-layer chromatographic method for the simultaneous determination of curcumin, metanil yellow, and sudan dyes in turmeric, chili, and curry powders.

Journal: Journal of AOAC International 20080101

Title: [Simultaneous determination of canthaxanthin and Sudan Red in salted duck egg yolk by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20071101

Title: Determination of banned 10 azo-dyes in hot chili products by gel permeation chromatography-liquid chromatography-electrospray ionization-tandem mass spectrometry.

Journal: Journal of chromatography. A 20070914

Title: [Determination of Sudan Red I-IV in duck egg yolk using ultra performance liquid chromatography-tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20070901

Title: Development of a new method for analysis of Sudan dyes by pressurized CEC with amperometric detection.

Journal: Electrophoresis 20070601

Title: Synthesis and characterization of a molecularly imprinted silica gel sorbent for the on-line determination of trace Sudan I in Chilli powder through high-performance liquid chromatography.

Journal: Journal of agricultural and food chemistry 20070516

Title: Sudan I induces genotoxic effects and oxidative DNA damage in HepG2 cells.

Journal: Mutation research 20070305

Title: Flow injection chemiluminescence determination of sudan I in hot chilli sauce.

Journal: Journal of agricultural and food chemistry 20070207

Title: Binding of Sudan II and IV to lecithin liposomes and E. coli membranes: insights into the toxicity of hydrophobic azo dyes.

Journal: BMC structural biology 20070101

Title: Fast cleanup method for the analysis of Sudan I-IV and para red in various foods and paprika color (oleoresin) by high-performance liquid chromatography/diode array detection: focus on removal of fat and oil as fatty acid methyl esters prepared by transesterification of acylglycerols.

Journal: Journal of AOAC International 20070101

Title: Direct method for determination of Sudan I in FD&C Yellow No. 6 and D&C Orange No. 4 by reversed-phase liquid chromatography.

Journal: Journal of AOAC International 20070101

Title: Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

Journal: Neuro endocrinology letters 20061201

Title: Development and optimization of an analytical method for the determination of Sudan dyes in hot chilli pepper by high-performance liquid chromatography with on-line electrogenerated BrO- -luminol chemiluminescence detection.

Journal: Journal of chromatography. A 20060929

Title: Determination of lycopene and beta-carotene by high-performance liquid chromatography using sudan I as internal standard.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060621

Title: [Effect of Sudan I, III and IV on proliferation of HepG-2 and SGC-7901].

Journal: Huan jing ke xue= Huanjing kexue 20060601

Title: Development of a fast analytical method for the determination of sudan dyes in chili- and curry-containing foodstuffs by high-performance liquid chromatography-photodiode array detection.

Journal: Journal of agricultural and food chemistry 20060208

Title: [Sudan and other illegal dyes--food adulteration].

Journal: Roczniki Panstwowego Zakladu Higieny 20060101

Title: Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers.

Journal: Cancer letters 20050408

Title: In vitro and in vivo metabolism of ethyl 4-[(2-hydroxy-1-naphthyl)azo]benzoate.

Journal: European journal of drug metabolism and pharmacokinetics 20050101

Title: Determination of 1-phenylazo-2-naphthol (Sudan I) in chilli powder and in chilli-containing food products by GPC clean-up and HPLC with LC/MS confirmation.

Journal: Food additives and contaminants 20041001

Title: Development and in-house validation of a liquid chromatography-electrospray-tandem mass spectrometry method for the simultaneous determination of Sudan I, Sudan II, Sudan III and Sudan IV in hot chilli products.

Journal: Journal of chromatography. A 20040709

Title: Fast determination of Sudan I by HPLC/APCI-MS in hot chilli, spices, and oven-baked foods.

Journal: Journal of agricultural and food chemistry 20040225

Title: Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Journal: Cancer research 20021015

Title: Modified short-term guinea pig sensitization tests for detecting contact allergens as an alternative to the conventional test.

Journal: Contact dermatitis 20010301

Title: Allergic contact dermatitis releases soluble factors that stimulate melanogenesis through activation of protein kinase C-related signal-transduction pathway.

Journal: The Journal of investigative dermatology 19921001

Title: Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis.

Journal: Toxicology and applied pharmacology 19890101

Title: Use of rat liver altered focus models for testing chemicals that have completed two-year carcinogenicity studies.

Journal: Toxicologic pathology 19890101

Title: Hongmiao Pan, et al. Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria. Anaerobe. 2012 Aug;18(4):445-53.

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