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84418-43-9,MFCD00237376
Catalog No.:AA003NIB

84418-43-9 | Fmoc-nh2

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1g
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$7.00   $5.00
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5g
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$13.00   $9.00
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10g
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$16.00   $11.00
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25g
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100g
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500g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NIB
Chemical Name:
Fmoc-nh2
CAS Number:
84418-43-9
Molecular Formula:
C15H13NO2
Molecular Weight:
239.2692
MDL Number:
MFCD00237376
SMILES:
NC(=O)OCC1c2ccccc2c2c1cccc2
Properties
Properties
 
BP:
459.7°C at 760 mmHg  
Form:
Liquid  
MP:
201-204 °C  
Solubility:
dioxane: 15 mg/mL, clear, colorless  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
296  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
2.7  

Literature

Title: Synthetic procedure for N-Fmoc amino acyl-N-sulfanylethylaniline linker as crypto-peptide thioester precursor with application to native chemical ligation.

Journal: The Journal of organic chemistry 20120817

Title: Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation.

Journal: European biophysics journal : EBJ 20120201

Title: Soluble peptidyl phosphoranes for metal-free, stereoselective ligations in organic and aqueous solution.

Journal: Organic letters 20120106

Title: Improved synthesis strategy for peptide nucleic acids (PNA) appropriate for cell-specific fluorescence imaging.

Journal: International journal of medical sciences 20120101

Title: Development of a novel biosensor using cationic antimicrobial Peptide and nickel phthalocyanine ultrathin films for electrochemical detection of dopamine.

Journal: International journal of analytical chemistry 20120101

Title: Enzymatic self-assembly of nanostructures for theranostics.

Journal: Theranostics 20120101

Title: Structure based design and synthesis of peptide inhibitor of human LOX-12: in vitro and in vivo analysis of a novel therapeutic agent for breast cancer.

Journal: PloS one 20120101

Title: Using self-assembled monolayers to understand α8β1-mediated cell adhesion to RGD and FEI motifs in nephronectin.

Journal: ACS chemical biology 20111021

Title: Synthetic strategy for side chain mono-N-alkylation of Fmoc-amino acids promoted by molecular sieves.

Journal: Amino acids 20111001

Title: Characterization of spontaneously generated prion-like conformers in cultured cells.

Journal: Aging 20111001

Title: The effect of purity upon the triple-helical stability of collagenous peptides.

Journal: Biomaterials 20110901

Title: Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol.

Journal: PLoS pathogens 20110901

Title: Immobilization of aptamer-based molecular beacons onto optically-encoded micro-sized beads.

Journal: Journal of nanoscience and nanotechnology 20110701

Title: The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways.

Journal: PloS one 20110101

Title: In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe.

Journal: PloS one 20110101

Title: Small lytic peptides escape the inhibitory effect of heparan sulfate on the surface of cancer cells.

Journal: BMC cancer 20110101

Title: A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach.

Journal: PloS one 20110101

Title: Enhancement of the click chemistry for the inverse Diels Alder technology by functionalization of amide-based monomers.

Journal: International journal of medical sciences 20110101

Title: Development of a method for environmentally friendly chemical peptide synthesis in water using water-dispersible amino acid nanoparticles.

Journal: Chemistry Central journal 20110101

Title: Syntheses and self-assembling behaviors of pentagonal conjugates of tryptophane zipper-forming peptide.

Journal: International journal of molecular sciences 20110101

Title: A Mycobacterium leprae Hsp65 mutant as a candidate for mitigating lupus aggravation in mice.

Journal: PloS one 20110101

Title: Design and development of a peptide-based adiponectin receptor agonist for cancer treatment.

Journal: BMC biotechnology 20110101

Title: Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation.

Journal: PloS one 20110101

Title: NNAlign: a web-based prediction method allowing non-expert end-user discovery of sequence motifs in quantitative peptide data.

Journal: PloS one 20110101

Title: A new era of cancer treatment: carbon nanotubes as drug delivery tools.

Journal: International journal of nanomedicine 20110101

Title: Adsorption of urinary proteins on the conventionally used urine collection tubes: possible effects on urinary proteome analysis and prevention of the adsorption by polymer coating.

Journal: International journal of proteomics 20110101

Title: Activity of Antimicrobial Peptides and Conventional Antibiotics against Superantigen Positive Staphylococcus aureus Isolated from the Patients with Neoplastic and Inflammatory Erythrodermia.

Journal: Chemotherapy research and practice 20110101

Title: Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin.

Journal: Angewandte Chemie (International ed. in English) 20101227

Title: Characterization of Nα-Fmoc-protected ureidopeptides by electrospray ionization tandem mass spectrometry (ESI-MS/MS): differentiation of positional isomers.

Journal: Journal of mass spectrometry : JMS 20101201

Title: Human OGA binds substrates in a conserved peptide recognition groove.

Journal: The Biochemical journal 20101115

Title: Synthesis and splice-redirecting activity of branched, arginine-rich peptide dendrimer conjugates of peptide nucleic acid oligonucleotides.

Journal: Bioconjugate chemistry 20101020

Title: Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation.

Journal: Carbohydrate research 20101013

Title: Hydrogelation through self-assembly of fmoc-peptide functionalized cationic amphiphiles: potent antibacterial agent.

Journal: The journal of physical chemistry. B 20100408

Title: Click chemistry aided synthesis of 1,4-substituted 1,2,3-triazole based N-Fmoc protected epsilon-amino acids: isolation, characterization and synthesis of novel triazole based unnatural amino acids.

Journal: Protein and peptide letters 20100401

Title: Structural basis of cell wall cleavage by a staphylococcal autolysin.

Journal: PLoS pathogens 20100301

Title: Semi-automated microwave-assisted SPPS: Optimization of protocols and synthesis of difficult sequences.

Journal: Biopolymers 20100101

Title: Anti-infective activity of apolipoprotein domain derived peptides in vitro: identification of novel antimicrobial peptides related to apolipoprotein B with anti-HIV activity.

Journal: BMC immunology 20100101

Title: Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids.

Journal: PloS one 20100101

Title: Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistry.

Journal: International journal of medical sciences 20100101

Title: Synthesis and Biological Evaluation of New CRH Analogues.

Journal: Bioinorganic chemistry and applications 20100101

Title: Identification of myotropic neuropeptides from the brain and corpus cardiacum-corpus allatum complex of the beetle, Zophobas atratus.

Journal: Journal of insect science (Online) 20100101

Title: Homodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporter.

Journal: PloS one 20100101

Title: Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin.

Journal: PloS one 20100101

Title: Synthesis of Peptides from α- and β-Tubulin Containing Glutamic Acid Side-Chain Linked Oligo-Glu with Defined Length.

Journal: International journal of peptides 20100101

Title: Crystallographic insight into collagen recognition by discoidin domain receptor 2.

Journal: Structure (London, England : 1993) 20091209

Title: A study of the dynamic interaction of surfactants with graphite and carbon nanotubes using Fmoc-amino acids as a model system.

Journal: Langmuir : the ACS journal of surfaces and colloids 20091006

Title: Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20091001

Title: Surface aggregation of urinary proteins and aspartic Acid-rich peptides on the faces of calcium oxalate monohydrate investigated by in situ force microscopy.

Journal: Calcified tissue international 20090601

Title: An amphipathic alpha-helix controls multiple roles of brome mosaic virus protein 1a in RNA replication complex assembly and function.

Journal: PLoS pathogens 20090301

Title: Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics.

Journal: PloS one 20090101

Title: Synthesis of 4-amino-thiazole analogs of Fmoc-amino acids and thiazole linked N-orthogonally protected dipeptidomimetics.

Journal: Protein and peptide letters 20090101

Title: The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells.

Journal: BMC cancer 20090101

Title: Administration of Mycobacterium leprae rHsp65 aggravates experimental autoimmune uveitis in mice.

Journal: PloS one 20090101

Title: Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation.

Journal: Organic & biomolecular chemistry 20081107

Title: Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis.

Journal: Biochemistry 20080729

Title: RNA interference in mammalia cells by RNA-3'-PNA chimeras.

Journal: International journal of molecular sciences 20080301

Title: Solid-phase synthesis of peptide and glycopeptide thioesters through side-chain-anchoring strategies.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels.

Journal: PloS one 20080101

Title: Serum antibodies to Porphyromonas gingivalis chaperone HtpG predict health in periodontitis susceptible patients.

Journal: PloS one 20080101

Title: A simple and economical method for the production of 13C,18O-labeled Fmoc-amino acids with high levels of enrichment: applications to isotope-edited IR studies of proteins.

Journal: Organic letters 20071122

Title: Solid-phase peptide synthesis using nanoparticulate amino acids in water.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20070701

Title: Enantioseparation by CE with vancomycin as chiral selector: Improving the separation performance by dynamic coating of the capillary with poly(dimethylacrylamide).

Journal: Electrophoresis 20070301

Title: Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding.

Journal: BMC neuroscience 20070101

Title: Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides.

Journal: BMC structural biology 20070101

Title: Self-assembling Fmoc dipeptide hydrogel for in situ 3D cell culturing.

Journal: BMC biotechnology 20070101

Title: Synthesis of libraries of 16beta-aminopropyl estradiol derivatives for targeting two key steroidogenic enzymes.

Journal: ChemMedChem 20061101

Title: [Separation of enantiomers of amino acid derivatives by high performance liquid chromatography on teicoplanin chiral stationary phase].

Journal: Se pu = Chinese journal of chromatography 20060301

Title: Chemical synthesis of analogs of the glycopeptide contulakin-G, an analgetically active conopeptide from Conus geographus.

Journal: Carbohydrate research 20060116

Title: Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: synthesis, characterization and cellular uptake.

Journal: Biomacromolecules 20060101

Title: Synthesis of spirohydantoins and spiro-2,5-diketopiperazines via resin-bound cyclic alpha,alpha-disubstituted alpha-amino esters.

Journal: Journal of combinatorial chemistry 20060101

Title: Facile solid-phase synthesis of C-terminal peptide aldehydes and hydroxamates from a common Backbone Amide-Linked (BAL) intermediate.

Journal: The journal of peptide research : official journal of the American Peptide Society 20051201

Title: Incorporation of pseudoproline derivatives allows the facile synthesis of human IAPP, a highly amyloidogenic and aggregation-prone polypeptide.

Journal: Organic letters 20050217

Title: Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization.

Journal: BMC immunology 20050101

Title: Identification of Fmoc-beta-Ala-OH and Fmoc-beta-Ala-amino acid-OH as new impurities in Fmoc-protected amino acid derivatives.

Journal: The journal of peptide research : official journal of the American Peptide Society 20050101

Title: Functional and structural characteristics of anticancer peptide Pep27 analogues.

Journal: Cancer cell international 20050101

Title: Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: Geometrical and conformational preferences of the 9-fluorenylmethoxycarbonyl-amino moiety.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20040701

Title: Small molecule hydrogels based on a class of antiinflammatory agents.

Journal: Chemical communications (Cambridge, England) 20040121

Title: Combinatorial library of peptidotriazoles: identification of [1,2,3]-triazole inhibitors against a recombinant Leishmania mexicana cysteine protease.

Journal: Journal of combinatorial chemistry 20040101

Title: Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein.

Journal: BMC structural biology 20040101

Title: Synthesis of various 3-substituted 1,2,4-oxadiazole-containing chiral beta 3- and alpha-amino acids from Fmoc-protected aspartic acid.

Journal: The Journal of organic chemistry 20030919

Title: The fluorenylmethoxycarbonyl group in solid phase synthesis.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20030901

Title: Antimicrobial peptides containing arginine.

Journal: Biochemistry. Biokhimiia 20030801

Title: Understanding protease catalysed solid phase peptide synthesis.

Journal: Organic & biomolecular chemistry 20030421

Title: Extensively stereodiversified scaffolds for use in diversity-oriented library synthesis.

Journal: Organic letters 20030306

Title: Traceless liquid phase synthesis of piperazinediones.

Journal: Combinatorial chemistry & high throughput screening 20030301

Title: Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides.

Journal: Journal of medicinal chemistry 20030213

Title: Liquid-phase peptide synthesis on polyethylene glycol (PEG) supports using strategies based on the 9-fluorenylmethoxycarbonyl amino protecting group: application of PEGylated peptides in biochemical assays.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20020901

Title: Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides.

Journal: The Journal of organic chemistry 20020503

Title: Cellular responses to Plasmodium falciparum erythrocyte membrane protein-1: use of relatively conserved synthetic peptide pools to determine CD4 T cell responses in malaria-exposed individuals in Benin, West Africa.

Journal: Malaria journal 20020101

Title: The 2-chlorotrityl resin: a worthy addition to the medicinal chemist's toolbox.

Journal: Current medicinal chemistry 20010501

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