84445-38-5,MFCD15145286
Catalog No.:AA004SG3

84445-38-5 | Uridine5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-

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Purity
Availability
Price(USD)
Quantity
  
1mg
2 weeks  
$949.00   $665.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA004SG3
Chemical Name:
Uridine5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-
CAS Number:
84445-38-5
Molecular Formula:
C9H11N2O13P3----
Molecular Weight:
448.1105
MDL Number:
MFCD15145286
SMILES:
O=c1ccn(c(=O)[nH]1)[C@H]1CC[C@H](O1)COP(=O)(OP(=O)(OP(=O)([O-])[O-])[O-])[O-]
Properties
Computed Properties
 
Complexity:
777  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-4.2  

Literature

Title: Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.

Journal: Journal of medicinal chemistry 20050407

Title: Investigation of the dNTP-binding site of HIV-1 reverse transcriptase using photoreactive analogs of dNTP.

Journal: Biochemistry. Biokhimiia 20010901

Title: Synthesis of the first ferrocene-labeled dideoxynucleotide and its use for 3'-redox end-labeling of 5'-modified single-stranded oligonucleotides.

Journal: Bioconjugate chemistry 20010101

Title: Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate.

Journal: Molecular pharmacology 19900201

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SDS
Tags:84445-38-5 Molecular Formula|84445-38-5 MDL|84445-38-5 SMILES|84445-38-5 Uridine5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-
Catalog No.: AA004SG3
84445-38-5,MFCD15145286
84445-38-5 | Uridine5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-
Pack Size: 1mg
Purity:
2 weeks
$949.00 $665.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA004SG3
Chemical Name: Uridine5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-
CAS Number: 84445-38-5
Molecular Formula: C9H11N2O13P3----
Molecular Weight: 448.1105
MDL Number: MFCD15145286
SMILES: O=c1ccn(c(=O)[nH]1)[C@H]1CC[C@H](O1)COP(=O)(OP(=O)(OP(=O)([O-])[O-])[O-])[O-]
Properties
Complexity: 777  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 27  
Hydrogen Bond Acceptor Count: 13  
Hydrogen Bond Donor Count: 5  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -4.2  
Literature fold

Title: Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.

Journal: Journal of medicinal chemistry20050407

Title: Investigation of the dNTP-binding site of HIV-1 reverse transcriptase using photoreactive analogs of dNTP.

Journal: Biochemistry. Biokhimiia20010901

Title: Synthesis of the first ferrocene-labeled dideoxynucleotide and its use for 3'-redox end-labeling of 5'-modified single-stranded oligonucleotides.

Journal: Bioconjugate chemistry20010101

Title: Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate.

Journal: Molecular pharmacology19900201

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