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[1]Patent:US2005/38068,2005,A1.Locationinpatent:Page/Pagecolumn70
[1]Patent:US2005/38068,2005,A1.Locationinpatent:Page/Pagecolumn51
[1]Patent:US2005/38068,2005,A1.Locationinpatent:Page/Pagecolumn53
105-36-2
[1]Patent:US2005/38068,2005,A1.Locationinpatent:Page/Pagecolumn37,65
Title: Effect of A-769662, a direct AMPK activator, on Tlr-4 expression and activity in mice heart tissue.
Journal: Iranian journal of basic medical sciences 20161201
Title: Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro.
Journal: Neuropharmacology 20160901
Title: Bavachalcone-induced manganese superoxide dismutase expression through the AMP-activated protein kinase pathway in human endothelial cells.
Journal: Pharmacology 20150101
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Activation of AMP-activated protein kinase inhibits the proliferation of human endothelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20120901
Title: Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells.
Journal: The Journal of biological chemistry 20120706
Title: The ancient drug salicylate directly activates AMP-activated protein kinase.
Journal: Science (New York, N.Y.) 20120518
Title: AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.
Journal: The Biochemical journal 20120401
Title: Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells.
Journal: Cell cycle (Georgetown, Tex.) 20120301
Title: Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS).
Journal: Analytical and bioanalytical chemistry 20120101
Title: 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent.
Journal: The Journal of pharmacology and experimental therapeutics 20111201
Title: A small molecule AMPK activator protects the heart against ischemia-reperfusion injury.
Journal: Journal of molecular and cellular cardiology 20110701
Title: Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway.
Journal: The Journal of pharmacology and experimental therapeutics 20110401
Title: AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells.
Journal: Diabetologia 20110101
Title: Escherichia coli expression, purification and characterization of functional full-length recombinant alpha2beta2gamma3 heterotrimeric complex of human AMP-activated protein kinase.
Journal: Protein expression and purification 20101001
Title: Stimulation of human and mouse erythrocyte Na(+)-K(+)-2Cl(-) cotransport by osmotic shrinkage does not involve AMP-activated protein kinase, but is associated with STE20/SPS1-related proline/alanine-rich kinase activation.
Journal: The Journal of physiology 20100701
Title: AMP-activated protein kinase induces actin cytoskeleton reorganization in epithelial cells.
Journal: Biochemical and biophysical research communications 20100604
Title: Regulation of Na+-coupled glucose carrier SGLT1 by AMP-activated protein kinase.
Journal: Molecular membrane biology 20100401
Title: Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.
Journal: Free radical research 20100201
Title: Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes.
Journal: The Journal of biological chemistry 20100115
Title: AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase.
Journal: American journal of physiology. Cell physiology 20091201
Title: A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle.
Journal: American journal of physiology. Cell physiology 20091001
Title: Inhibitory effects of A-769662, a novel activator of AMP-activated protein kinase, on 3T3-L1 adipogenesis.
Journal: Biological & pharmaceutical bulletin 20090601
Title: AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells.
Journal: American journal of physiology. Cell physiology 20090401
Title: Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle.
Journal: Endocrinology 20090201
Title: Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators.
Journal: IUBMB life 20090101
Title: Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.
Journal: Chemistry & biology 20081124
Title: Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.
Journal: The Journal of biological chemistry 20071109
Title: Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.
Journal: The Journal of biological chemistry 20071109
Title: Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome.
Journal: Cell metabolism 20060601
Title: Cool B, et al. Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab, 2006, 3(6), 403-416.
Title: Sanders MJ, et al. Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family. J Biol Chem, 2007, 282(45), 32539-32548.
Title: Moreno D, et al, A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism. FEBS Lett, 2008, 583(17), 2650-2654.
Title: Yerra VG, et al. Adenosine Monophosphate-Activated Protein Kinase Abates Hyperglycaemia-Induced Neuronal Injury in Experimental Models of Diabetic Neuropathy: Effects on Mitochondrial Biogenesis, Autophagy and Neuroinflammation. Mol Neurobiol. 2017 Apr;54(3):2301-2312.
