Home Amines 84485-00-7
84485-00-7,MFCD04039806
Catalog No.:AA00JOBX

84485-00-7 | 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrochloride

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00JOBX
Chemical Name:
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrochloride
CAS Number:
84485-00-7
Molecular Formula:
C17H27Cl2N
Molecular Weight:
316.3090
MDL Number:
MFCD04039806
SMILES:
CC(CC(C1(CCC1)c1ccc(cc1)Cl)N(C)C)C.Cl
NSC Number:
758928
Properties
Computed Properties
 
Complexity:
275  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Sibutramine provokes apoptosis of aortic endothelial cells through altered production of reactive oxygen and nitrogen species.

Journal: Toxicology and applied pharmacology 20170101

Title: Effects of oral anorexiant sibutramine on the expression of cytochromes P450s in human hepatocytes and cancer cell lines.

Journal: Journal of biochemical and molecular toxicology 20131201

Title: Short-term effects of sibutramine on mineral status and selected biochemical parameters in obese women.

Journal: Biological trace element research 20121101

Title: Evaluation of body fat composition after linagliptin treatment in a rat model of diet-induced obesity: a magnetic resonance spectroscopy study in comparison with sibutramine.

Journal: Diabetes, obesity & metabolism 20121101

Title: Evaluation of mutagenic effect of two antiobesity drugs on mice's genetic materials.

Journal: Drug and chemical toxicology 20121001

Title: Calorimetric, FTIR and 1H NMR measurements in combination with DFT calculations for monitoring solid-state changes of dynamics of sibutramine hydrochloride.

Journal: Journal of pharmaceutical sciences 20121001

Title: Partial conversion of methanol to formaldehyde in the gas chromatography injection port and reactivity with amines.

Journal: Journal of chromatography. A 20120928

Title: Changes of cytosolic calcium and contractility of young rat vas deferens by acute treatment with amphetamine, fluoxetine or sibutramine.

Journal: European journal of pharmacology 20120915

Title: Sibutramine administration decreases serum anti-Müllerian hormone (AMH) levels in women with polycystic ovary syndrome.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20120801

Title: Rapid screening of illicit additives in weight loss dietary supplements with desorption corona beam ionisation (DCBI) mass spectrometry.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120801

Title: Safety assessment of an anti-obesity drug (sibutramine): a retrospective cohort study.

Journal: Drug safety 20120801

Title: Maintained intentional weight loss reduces cardiovascular outcomes: results from the Sibutramine Cardiovascular OUTcomes (SCOUT) trial.

Journal: Diabetes, obesity & metabolism 20120601

Title: Sibutramine promotes amygdala activity under fasting conditions in obese women.

Journal: Psychopharmacology 20120601

Title: A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20120601

Title: Prediction of weight loss and regain following dietary, lifestyle, and pharmacologic intervention.

Journal: Clinical pharmacology and therapeutics 20120601

Title: Effect of sibutramine on 5-hydroxyindole acetic acid levels and selected oxidative biomarkers on brain regions of female rats in the presence of zinc.

Journal: Basic & clinical pharmacology & toxicology 20120501

Title: Management of obesity in the National Health and Nutrition Examination Survey (NHANES), 2007-2008.

Journal: Annals of epidemiology 20120501

Title: Comparative determination of sibutramine as an adulterant in natural slimming products by HPLC and HPTLC densitometry.

Journal: Journal of pharmaceutical and biomedical analysis 20120501

Title: Food and Drug Administration's Obesity Drug Guidance Document: a short history.

Journal: Circulation 20120501

Title: Intragastric balloon in association with lifestyle and/or pharmacotherapy in the long-term management of obesity.

Journal: Obesity surgery 20120401

Title: Serotonin syndrome following overdose of a non-prescription slimming product containing sibutramine: a case report.

Journal: Human & experimental toxicology 20120401

Title: Olanzapine and sibutramine have opposing effects on the motivation for palatable food.

Journal: Behavioural pharmacology 20120401

Title: The perils of pharmacological treatment for obesity: a case of sibutramine-associated cardiomyopathy and malignant arrhythmias.

Journal: Cardiovascular journal of Africa 20120312

Title: [The pharmacological treatment of obesity: past, present and future].

Journal: Orvosi hetilap 20120311

Title: What cost weight loss?

Journal: Circulation 20120306

Title: Multidisciplinary intervention with sibutramine: assessing successful weight loss predictors in military adolescent dependents.

Journal: Military medicine 20120301

Title: Chiral discrimination of sibutramine enantiomers by capillary electrophoresis and proton nuclear magnetic resonance spectroscopy.

Journal: Archives of pharmacal research 20120301

Title: Serotonin receptor 2A -1438G/A promoter polymorphism in relation to obesity and response to sibutramine.

Journal: Genetic testing and molecular biomarkers 20120201

Title: Effects of liraglutide and sibutramine on food intake, palatability, body weight and glucose tolerance in the gubra DIO-rats.

Journal: Acta pharmacologica Sinica 20120201

Title: Weight loss significantly reduces serum lipocalin-2 levels in overweight and obese women with polycystic ovary syndrome.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20120101

Title: Use of a pharmaceutically adulterated dietary supplement, Pai You Guo, among Brazilian-born women in the United States.

Journal: Journal of general internal medicine 20120101

Title: Sibutramine for the treatment of recurrent high-flow priapism.

Journal: Journal of andrology 20120101

Title: What is the clinical effectiveness and cost-effectiveness of using drugs in treating obese patients in primary care? A systematic review.

Journal: Health technology assessment (Winchester, England) 20120101

Title: Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells.

Journal: PloS one 20120101

Title: Sibutramine-induced mania as the first manifestation of bipolar disorder.

Journal: BMC psychiatry 20120101

Title: A GC-EI-MS-MS method for simultaneous determination of seven adulterants in slimming functional foods.

Journal: Journal of chromatographic science 20120101

Title: Experimental study of the effects of Dietressa, a new weight-reducing drug.

Journal: Bulletin of experimental biology and medicine 20120101

Title: A new approach to determining pharmacologic adulteration of herbal weight loss products.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: X-ray powder diffractometry and liquid chromatography studies of sibutramine and its analogues content in herbal dietary supplements.

Journal: Journal of pharmaceutical and biomedical analysis 20111215

Title: Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites.

Journal: Journal of clinical pharmacology 20111201

Title: Long-term health benefits of appetite suppressants remain unproven.

Journal: Revista de saude publica 20111201

Title: Determination of tadalafil and N-desmethylsibutramine in health and dietary supplements using ultra-performance liquid chromatography (UPLC) coupled with quadrupole-time-of-flight mass spectrometry (Q-TOF MS).

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20111101

Title: Adherence to weight loss medications; post-marketing study from HMO pharmacy data of one million individuals.

Journal: Diabetes research and clinical practice 20111101

Title: Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods.

Journal: Journal of chromatography. A 20111021

Title: Variation of inflammatory parameters after sibutramine treatment compared to placebo in type 2 diabetic patients.

Journal: Journal of clinical pharmacy and therapeutics 20111001

Title: Inverse agonism at α2A adrenoceptors augments the hypophagic effect of sibutramine in rats.

Journal: Obesity (Silver Spring, Md.) 20111001

Title: Is there a path for approval of an antiobesity drug: what did the Sibutramine Cardiovascular Outcomes Trial find?

Journal: Current opinion in endocrinology, diabetes, and obesity 20111001

Title: Topiramate induces weight loss and improves insulin sensitivity in dietary obese rats: comparison to sibutramine.

Journal: European review for medical and pharmacological sciences 20111001

Title: Drug treatment for obesity in the post-sibutramine era.

Journal: Drug safety 20110801

Title: [Pharmacological concepts for the treatment of obesity - a therapeutic meander?].

Journal: Deutsche medizinische Wochenschrift (1946) 20110801

Title: [Simultaneous determination of 15 anti-obesity drugs in blood by high performance liquid chromatography-tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20110801

Title: Sibutramine: balanced judgment or prejudice?

Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20110601

Title: No compelling evidence that sibutramine prolongs life in rodents despite providing a dose-dependent reduction in body weight.

Journal: International journal of obesity (2005) 20110501

Title: Sibutramine on cardiovascular outcome.

Journal: Diabetes care 20110501

Title: Comparative efficiency and safety of pharmacological approaches to the management of obesity.

Journal: Diabetes care 20110501

Title: Reverse migration order of sibutramine enantiomers as a function of cyclodextrin concentration in capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20110405

Title: Reversal of sibutramine-induced anorexia with a selective 5-HT(2C) receptor antagonist.

Journal: Psychopharmacology 20110401

Title: Proteome changes in rat plasma in response to sibutramine.

Journal: Proteomics 20110401

Title: Effects of combination of sibutramine and L-carnitine compared with sibutramine monotherapy on inflammatory parameters in diabetic patients.

Journal: Metabolism: clinical and experimental 20110301

Title: Changes of body weight and inflammatory markers after 12-week intervention trial: results of a double-blind, placebo-control pilot study.

Journal: Yonsei medical journal 20110301

Title: Pharmacological treatment of obesity: a public health perspective.

Journal: Cadernos de saude publica 20110301

Title: [Long-term effects of weight-reducing drugs in hypertensive patients--a survey of a Cochrane review].

Journal: Ugeskrift for laeger 20110221

Title: Using a portable ion mobility spectrometer to screen dietary supplements for sibutramine.

Journal: Journal of pharmaceutical and biomedical analysis 20110220

Title: The identification of rimonabant polymorphs, sibutramine and analogues of both in counterfeit Acomplia bought on the internet.

Journal: Journal of pharmaceutical and biomedical analysis 20110105

Title: Effect of CYP2B6 genotype on the pharmacokinetics of sibutramine and active metabolites in healthy subjects.

Journal: Journal of clinical pharmacology 20110101

Title: The effect of weight loss and treatment with metformin on serum vaspin levels in women with polycystic ovary syndrome.

Journal: Endocrine journal 20110101

Title: [Moxibustion on the Governor Vessel for lung and kidney qi deficiency type in chronic obstructive pulmonary disease: a randomized controlled trial].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20110101

Title: Hepatic PTP1B expression involvement in the effects of Chinese medicine formula xiao-gao-jiang-zhuo using an obese rat model.

Journal: The American journal of Chinese medicine 20110101

Title: Impact of waist circumference reduction on cardiovascular risk in treated obese subjects.

Journal: Cirugia y cirujanos 20110101

Title: Acceleration of sperm transit time and reduction of sperm reserves in the epididymis of rats exposed to sibutramine.

Journal: Journal of andrology 20110101

Title: [Sibutramine and its adequate usage].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110101

Title: Systematic review of the clinical efficacy of sibutramine and orlistat in weigth loss, quality of life and its adverse effects in obese adolescents.

Journal: Nutricion hospitalaria 20110101

Title: Hypogonadotropic hypogonadism in a homozygous MC4R mutation carrier and the effect of sibutramine treatment on body weight and obesity-related health risks.

Journal: Obesity facts 20110101

Title: [Adverse drug reactions of a slimming product contaminated with sibutramine].

Journal: Nederlands tijdschrift voor geneeskunde 20110101

Title: Cost-effectiveness of pharmacotherapy to reduce obesity.

Journal: PloS one 20110101

Title: A case of sibutramine-induced hyperprolactinemia.

Journal: Neuro endocrinology letters 20110101

Title: Study on detection of drugs in slimming health foods using GC-MS/MS.

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20110101

Title: [The obesity and way for treatment].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20110101

Title: Simultaneous thin-layer chromatography-densitometric analysis of sibutramine and citalopram.

Journal: Folia medica 20110101

Title: Long-term changes in blood pressure following orlistat and sibutramine treatment: a meta-analysis.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20101101

Title: Effects of acute low-dose combined treatment with rimonabant and sibutramine on appetite and weight gain in rats.

Journal: Pharmacology, biochemistry, and behavior 20101101

Title: Elevation of QT dispersion after obesity drug sibutramine.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Sibutramine (Meridia) withdrawn.

Journal: The Medical letter on drugs and therapeutics 20101101

Title: Distinct modulatory effects of satiety and sibutramine on brain responses to food images in humans: a double dissociation across hypothalamus, amygdala, and ventral striatum.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20101027

Title: Contrasting effects of systemic and central sibutramine administration on the intake of a palatable diet in the rat.

Journal: Neuroscience letters 20101022

Title: European Medicines Agency withdrawal for sibutramine.

Journal: Archives of disease in childhood 20101001

Title: Hypothalamic orexin and pro-opiomelanocortin activities are essential for the anorexic effects of m-chlorophenylpiperazine in mice.

Journal: The international journal of neuropsychopharmacology 20101001

Title: Recurrent episodes of brief affective psychosis induced by sibutramine.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20101001

Title: Psychosis associated with usage of herbal slimming products adulterated with sibutramine: a case series.

Journal: Clinical toxicology (Philadelphia, Pa.) 20101001

Title: [Classified teaching of acupoints: standardized teaching in Jingluo Shuxue Xue (Channels and Acupoints science)].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20101001

Title: [Suspension of the commercialization of sibutramine and rosiglitazone in Europe].

Journal: Revue medicale de Liege 20101001

Title: Development of novel sibutramine base-loaded solid dispersion with gelatin and HPMC: physicochemical characterization and pharmacokinetics in beagle dogs.

Journal: International journal of pharmaceutics 20100915

Title: Weight loss maintenance.

Journal: American family physician 20100915

Title: Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects.

Journal: The New England journal of medicine 20100902

Title: Sibutramine--another flawed diet pill.

Journal: The New England journal of medicine 20100902

Title: Comparison of the effects of sibutramine versus sibutramine plus metformin in obese women.

Journal: Clinical and experimental medicine 20100901

Title: Enhanced weight loss following coadministration of pramlintide with sibutramine or phentermine in a multicenter trial.

Journal: Obesity (Silver Spring, Md.) 20100901

Title: Long-term characterization of the diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome.

Journal: The Journal of endocrinology 20100901

Title: Fat attack.

Journal: Scientific American 20100901

Title: [The trial that killed a drug].

Journal: Lakartidningen 20100901

Title: [Withdrawal of sibutramine for cardiovascular disease risk].

Journal: Revista peruana de medicina experimental y salud publica 20100901

Title: [Simultaneous determination of five illegal drugs in weight control foods with solid phase extraction-high performance liquid chromatography].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100901

Title: Assessment of the application of the intragastric balloon together with sibutramine: a prospective clinical study.

Journal: Obesity surgery 20100801

Title: Efficacy and safety of anti-obesity drugs in children and adolescents: systematic review and meta-analysis.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20100801

Title: Myocardial infarction associated with sibutramine use: case report and discussion.

Journal: Military medicine 20100801

Title: Drug management of obesity--efficacy versus safety.

Journal: The New England journal of medicine 20100715

Title: Analysis of adulterated herbal medicines and dietary supplements marketed for weight loss by DOSY 1H-NMR.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100701

Title: Fatal and non-fatal cardiovascular events in a general population prescribed sibutramine in New Zealand: a prospective cohort study.

Journal: Drug safety 20100701

Title: Controversy about the cardiovascular safety of sibutramine.

Journal: Drug safety 20100701

Title: The novel triple monoamine reuptake inhibitor tesofensine induces sustained weight loss and improves glycemic control in the diet-induced obese rat: comparison to sibutramine and rimonabant.

Journal: European journal of pharmacology 20100625

Title: Office-based strategies for the management of obesity.

Journal: American family physician 20100615

Title: Cardiac valve evaluation and adipokine levels in obese women treated with sibutramine.

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20100601

Title: Withdrawal of sibutramine for weight loss: where does this leave clinicians?

Journal: Obesity facts 20100601

Title: Absence of sibutramine effect on spontaneous anxiety in rats.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20100601

Title: Sibutramine: cardiovascular events.

Journal: Prescrire international 20100601

Title: Early response to sibutramine in patients not meeting current label criteria: preliminary analysis of SCOUT lead-in period.

Journal: Obesity (Silver Spring, Md.) 20100501

Title: [32-year-old patient with acute myocardial infarction possibly induced by the appetite suppressant sibutramine].

Journal: Deutsche medizinische Wochenschrift (1946) 20100501

Title: Variegate porphyria in a 46-year-old patient taking sibutramine for weight loss.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20100401

Title: Effect of the common -866G/A polymorphism of the uncoupling protein 2 gene on weight loss and body composition under sibutramine therapy in an obese Taiwanese population.

Journal: Molecular diagnosis & therapy 20100401

Title: Withdrawal of sibutramine. Editorial is judgment in advance of the facts.

Journal: BMJ (Clinical research ed.) 20100310

Title: Withdrawal of sibutramine. Magic bullets now uncontrolled.

Journal: BMJ (Clinical research ed.) 20100310

Title: Use of psychotropic drugs and analgesics among users of antiobesity drugs--a population based study.

Journal: Pharmacoepidemiology and drug safety 20100301

Title: An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex.

Journal: Human & experimental toxicology 20100301

Title: Pharmacologic therapies for obesity.

Journal: Gastroenterology clinics of North America 20100301

Title: Transient global amnesia after taking sibutramine: a case report.

Journal: The neurologist 20100301

Title: An obesity drug sibutramine reduces brain natriuretic peptide (BNP) levels in severely obese patients.

Journal: International journal of clinical practice 20100301

Title: Sibutramine & naloxone: infra-additive interaction in the regulation of appetite?

Journal: Behavioural brain research 20100211

Title: Withdrawal of sibutramine in Europe.

Journal: BMJ (Clinical research ed.) 20100209

Title: Efficacy of weight loss drugs on obesity and cardiovascular risk factors in obese adolescents: a meta-analysis of randomized controlled trials.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20100201

Title: Brain serotonin transporter occupancy by oral sibutramine dosed to steady state: a PET study using (11)C-DASB in healthy humans.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100201

Title: Effectiveness of weight management interventions in children: a targeted systematic review for the USPSTF.

Journal: Pediatrics 20100201

Title: Acute coronary syndrome in a young woman treated with sibutramine.

Journal: Revista espanola de cardiologia 20100201

Title: Enantioselective pharmacokinetics of sibutramine in rat.

Journal: Archives of pharmacal research 20100201

Title: [Clinical observation on therapeutic effect of electric-heat needle combined with acupoint sticking therapy for treatment of simple obesity].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20100201

Title: [Back at the starting point. Obesity patients the losers when sibutramine (Reductil) is recalled].

Journal: Lakartidningen 20100201

Title: Withdrawal of sibutramine leaves European doctors with just one obesity drug.

Journal: BMJ (Clinical research ed.) 20100125

Title: [Questions surrounding sibutramine for obesity].

Journal: Revue medicale suisse 20100113

Title: Enantioselective determination of sibutramine and its active metabolites in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20100105

Title: The effects of sibutramine on the microstructure of eating behaviour and energy expenditure in obese women.

Journal: Journal of psychopharmacology (Oxford, England) 20100101

Title: Weight and blood pressure response to weight management and sibutramine in diabetic and non-diabetic high-risk patients: an analysis from the 6-week lead-in period of the sibutramine cardiovascular outcomes (SCOUT) trial.

Journal: Diabetes, obesity & metabolism 20100101

Title: Sibutramine selective electrodes for batch and flow injection determinations in pharmaceutical preparations.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

Title: Enhanced solubility and bioavailability of sibutramine base by solid dispersion system with aqueous medium.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Various emetogens increase the secretion of salivary amylase in rats: a potential model in emesis research.

Journal: Journal of pharmacological sciences 20100101

Title: Sibutramine effects on the reproductive performance of pregnant overweight and non-overweight rats.

Journal: Journal of toxicology and environmental health. Part A 20100101

Title: Sibutramine and L-carnitine compared to sibutramine alone on insulin resistance in diabetic patients.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Cardiovascular risk-benefit profile of sibutramine.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101

Title: [Effect of sibutramine (meridia) on body composition, peptide YY3-36 and serotonin levels in patients with exogenous constitutional obesity].

Journal: Terapevticheskii arkhiv 20100101

Title: Effects of one year treatment of sibutramine on insulin resistance parameters in type 2 diabetic patients.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

Title: [First-episode mania with psychotic features induced by over-the-counter diet aids containing sibutramine].

Journal: Turk psikiyatri dergisi = Turkish journal of psychiatry 20100101

Title: Highly enantioselective catalytic asymmetric synthesis of a (R)-sibutramin precursor.

Journal: Chimia 20100101

Title: [Medicinal drug resemble ingredients in health foods].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20100101

Title: [About the withdrawal of sibutramine in Peru].

Journal: Revista peruana de medicina experimental y salud publica 20100101

Title: Simultaneous determination of anti-diabetes/anti-obesity drugs by LC/PDA, and targeted analysis of sibutramine analog in dietary supplements by LC/MS/MS.

Journal: Biomedical chromatography : BMC 20091201

Title: Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy.

Journal: Clinical pharmacology and therapeutics 20091201

Title: Sibutramine for weight gain attenuation during smoking cessation with varenicline: a pilot study.

Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20091201

Title: Practical methods for improving flow properties of active pharmaceutical ingredients.

Journal: Drug development and industrial pharmacy 20091201

Title: Rise in antiobesity drug prescribing for children and adolescents in the UK: a population-based study.

Journal: British journal of clinical pharmacology 20091201

Title: Association of CYP2B6, CYP3A5, and CYP2C19 genetic polymorphisms with sibutramine pharmacokinetics in healthy Korean subjects.

Journal: Clinical pharmacology and therapeutics 20091101

Title: Treatment with sibutramine prior to Roux-en-Y gastric bypass leads to an improvement of metabolic parameters and to a reduction of liver size and operative time.

Journal: Obesity surgery 20091101

Title: Evaluation of anti-obesity activity of duloxetine in comparison with sibutramine along with its anti-depressant activity: an experimental study in obese rats.

Journal: Canadian journal of physiology and pharmacology 20091101

Title: Changes in regional adiposity and cardio-metabolic function following a weight loss program with sibutramine in obese men with obstructive sleep apnea.

Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20091015

Title: Acute myocardial infarction in a 24 year-old man possibly associated with sibutramine use.

Journal: International journal of cardiology 20091002

Title: Analysis of sibutramine metabolites as N-trifluoroacetamide and O-trimethylsilyl derivatives by gas chromatography-mass spectrometry in urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

Title: What are the risks and the benefits of current and emerging weight-loss medications?

Journal: Current diabetes reports 20091001

Title: Comparative bioavailability of two formulations of sibutramine.

Journal: International journal of clinical pharmacology and therapeutics 20091001

Title: Multiple effects of sibutramine on ejaculation and on vas deferens and seminal vesicle contractility.

Journal: Toxicology and applied pharmacology 20090915

Title: Analysis of enantiomers of sibutramine and its metabolites in rat plasma by liquid chromatography-mass spectrometry using a chiral stationary-phase column.

Journal: Journal of pharmaceutical and biomedical analysis 20090908

Title: Sibutramine versus continuous positive airway pressure in obese obstructive sleep apnoea patients.

Journal: The European respiratory journal 20090901

Title: Pre-exposure to environmental cues predictive of food availability elicits hypothalamic-pituitary-adrenal axis activation and increases operant responding for food in female rats.

Journal: Addiction biology 20090901

Title: Discontinuation due to adverse events in randomized trials of orlistat, sibutramine and rimonabant: a meta-analysis.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20090901

Title: Weight loss and body fat reduction under sibutramine therapy in obesity with the C825T polymorphism in the GNB3 gene.

Journal: Pharmacogenetics and genomics 20090901

Title: Pharmacotherapy in pediatric obesity: current agents and future directions.

Journal: Reviews in endocrine & metabolic disorders 20090901

Title: A retrospective review of California poison control system data of sibutramine exposures.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090901

Title: Crude herbal drugs may be safe.

Journal: Deutsches Arzteblatt international 20090901

Title: Acute effect of weight loss on levels of total bilirubin in obese, cardiovascular high-risk patients: an analysis from the lead-in period of the Sibutramine Cardiovascular Outcome trial.

Journal: Metabolism: clinical and experimental 20090801

Title: Predictors of attrition and weight loss success: Results from a randomized controlled trial.

Journal: Behaviour research and therapy 20090801

Title: Long-term effects of weight-reducing drugs in hypertensive patients.

Journal: The Cochrane database of systematic reviews 20090708

Title: Effect of antiobesity medications in patients with type 2 diabetes mellitus.

Journal: Diabetes, obesity & metabolism 20090701

Title: Sibutramine-induced recurrent seizures.

Journal: Epilepsy & behavior : E&B 20090701

Title: Serotonin syndrome following sibutramine poisoning in a child, with sequential quantification of sibutramine and its primary and secondary amine metabolites in plasma.

Journal: Clinical toxicology (Philadelphia, Pa.) 20090701

Title: Effect of sibutramine on weight reduction and insulin resistance in women with polycystic ovary syndrome.

Journal: Fertility and sterility 20090601

Title: [Pharmaceutical treatment of binge eating disorder].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20090601

Title: A preclinical model of binge eating elicited by yo-yo dieting and stressful exposure to food: effect of sibutramine, fluoxetine, topiramate, and midazolam.

Journal: Psychopharmacology 20090501

Title: Effect of sibutramine on Na+, K+ ATPase activity and tryptophan levels on male and female rat brain.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090501

Title: Changes in symptoms of depression with weight loss: results of a randomized trial.

Journal: Obesity (Silver Spring, Md.) 20090501

Title: Serum adiponectin and resistin in rats under three isocaloric diets: The effect of sibutramine.

Journal: Cytokine 20090501

Title: Effects of sibutramine and rimonabant in rats trained to discriminate between 22- and 2-h food deprivation.

Journal: Psychopharmacology 20090401

Title: Melanin-concentrating hormone-1 receptor antagonism and anti-obesity effects of ethanolic extract from Morus alba leaves in diet-induced obese mice.

Journal: Journal of ethnopharmacology 20090318

Title: Sibutramine-induced anorexia: potent, dose-dependent and behaviourally-selective profile in male rats.

Journal: Behavioural brain research 20090317

Title: Blood pressure changes associated with sibutramine and weight management - an analysis from the 6-week lead-in period of the sibutramine cardiovascular outcomes trial (SCOUT).

Journal: Diabetes, obesity & metabolism 20090301

Title: 5-HT(1A) activation counteracts cardiovascular but not hypophagic effects of sibutramine in rats.

Journal: Obesity (Silver Spring, Md.) 20090301

Title: The anorexic agents, sibutramine and fenfluramine, depress GABA(B)-induced inhibitory postsynaptic potentials in rat mesencephalic dopaminergic cells.

Journal: British journal of pharmacology 20090301

Title: The first decade of sibutramine and orlistat: a reappraisal of their expanding roles in the treatment of obesity and associated conditions.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20090301

Title: Chinese slimming capsules containing sibutramine sold over the Internet: a case series.

Journal: Deutsches Arzteblatt international 20090301

Title: Bonghan system as mesenchymal stem cell niches and pathways of macrophages in adipose tissues.

Journal: Journal of acupuncture and meridian studies 20090301

Title: Demo-experiments of Bonghan ducts in Beijing.

Journal: Journal of acupuncture and meridian studies 20090301

Title: Comparison of methods for delivering a lifestyle modification program for obese patients: a randomized trial.

Journal: Annals of internal medicine 20090217

Title: Characterization of metabolites of sibutramine in primary cultures of rat hepatocytes by liquid chromatography-ion trap mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20090201

Title: Current pharmacotherapeutic concepts for the treatment of obesity in adults.

Journal: Therapeutic advances in cardiovascular disease 20090201

Title: Effect of sibutramine HCl on cardiac hERG K+ channel.

Journal: Molecular and cellular biochemistry 20090101

Title: Pharmacotherapy for eating disorders and obesity.

Journal: Child and adolescent psychiatric clinics of North America 20090101

Title: Recent advances in obesity pharmacotherapy.

Journal: Current clinical pharmacology 20090101

Title: Pioglitazone metabolic effect in metformin-intolerant obese patients treated with sibutramine.

Journal: Internal medicine (Tokyo, Japan) 20090101

Title: Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis.

Journal: BMC psychiatry 20090101

Title: Development and validation of a column high-performance liquid chromatographic method for determination of sibutramine in capsules.

Journal: Journal of AOAC International 20090101

Title: The use of sibutramine in the management of obesity and related disorders: an update.

Journal: Vascular health and risk management 20090101

Title: [Drug treatment of obesity].

Journal: Revue medicale de Bruxelles 20090101

Title: Pharmacotherapy and surgery treatment for the severely obese adolescent.

Journal: Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20090101

Title: Sibutramine--its impact on health-related quality of life and depression among adult obese non-diabetic patients.

Journal: Bratislavske lekarske listy 20090101

Title: What extent of weight loss can benefit the health-related quality of life in motivated obese Chinese?

Journal: Asia Pacific journal of clinical nutrition 20090101

Title: Comparison of rimonabant and sibutramine treatment effects on food compulsion in rats.

Journal: Acta cirurgica brasileira 20090101

Title: [Sibutramine-related panic attack: a clinical case of apparent resolution with paroxetine].

Journal: Rivista di psichiatria 20090101

Title: Influence of sibutramine, orlistat and Ispaghula in reducing body weight and total body fat content in obese individuals.

Journal: Journal of Ayub Medical College, Abbottabad : JAMC 20090101

Title: Crystal chemistry of sibutramine: thermal, diffractometric and spectroscopic characterization.

Journal: Journal of pharmaceutical sciences 20081201

Title: Cost-effectiveness of pharmacological anti-obesity treatments: a systematic review.

Journal: International journal of obesity (2005) 20081201

Title: A possible mechanism for severe symptomatic hyponatremia during sibutramine therapy.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20081201

Title: Hypomanic episode secondary to sibutramine in a patient with type-I bipolar disorder.

Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20081201

Title: Sibutramine-induced acute myocardial infarction in a young lady.

Journal: Clinical toxicology (Philadelphia, Pa.) 20081101

Title: Sibutramine-induced psychotic episode in an adolescent.

Journal: Journal of psychosomatic research 20081101

Title: Sibutramine effect on metabolic control of obese patients with type 2 diabetes mellitus treated with pioglitazone.

Journal: Metabolism: clinical and experimental 20081101

Title: Implementing antiobesity treatment in a patient with a mood disorder.

Journal: Journal of psychiatry & neuroscience : JPN 20081101

Title: Tolerability of sibutramine during a 6-week treatment period in high-risk patients with cardiovascular disease and/or diabetes: a preliminary analysis of the Sibutramine Cardiovascular Outcomes (SCOUT) Trial.

Journal: Journal of cardiovascular pharmacology 20081101

Title: Can sibutramine alter systemic blood pressure in obese patients? Systematic review and meta-analysis.

Journal: Sao Paulo medical journal = Revista paulista de medicina 20081101

Title: Request for slimming tablets.

Journal: BMJ (Clinical research ed.) 20081024

Title: Abdominal visceral fat reduction is associated with favorable changes of serum retinol binding protein-4 in nondiabetic subjects.

Journal: Endocrine journal 20081001

Title: The effect of sibutramine therapy on occurrence of depression symptoms among obese patients.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20081001

Title: A controlled pharmacogenetic trial of sibutramine on weight loss and body composition in obese or overweight adults.

Journal: Gastroenterology 20081001

Title: Sibutramine-associated QT interval prolongation and cardiac arrest.

Journal: The Annals of pharmacotherapy 20081001

Title: [Association of obesity and depression].

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20081001

Title: Head-to-head studies evaluating efficacy of pharmaco-therapy for obesity: a systematic review and meta-analysis.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20080901

Title: Effect of sibutramine on regional fat pads and leptin levels in rats fed with three isocaloric diets.

Journal: European cytokine network 20080901

Title: Simultaneous determination of sibutramine and N-Di-desmethylsibutramine in dietary supplements for weight control by HPLC-ESI-MS.

Journal: Journal of chromatographic science 20080901

Title: [Obesity and oral health: risk factors of obese patients in dental practice].

Journal: Odonto-stomatologie tropicale = Tropical dental journal 20080901

Title: Effectiveness of weight management programs in children and adolescents.

Journal: Evidence report/technology assessment 20080901

Title: Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats.

Journal: International journal of obesity (2005) 20080801

Title: Determination of the active metabolites of sibutramine in rat serum using column-switching HPLC.

Journal: Journal of separation science 20080801

Title: Sibutramine: current status as an anti-obesity drug and its future perspectives.

Journal: Expert opinion on pharmacotherapy 20080801

Title: Sibutramine-associated adverse effects: a practical guide for its safe use.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20080701

Title: Effects of a novel Y5 antagonist in obese mice: combination with food restriction or sibutramine.

Journal: Obesity (Silver Spring, Md.) 20080701

Title: Severe symptomatic hyponatremia during sibutramine therapy: a case report.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20080701

Title: Effects of sibutramine plus verapamil sustained release/trandolapril combination on blood pressure and metabolic variables in obese hypertensive patients.

Journal: Expert opinion on pharmacotherapy 20080701

Title: Concerns about the safety of obesity agents from a manufacturing perspective.

Journal: Postgraduate medicine 20080701

Title: Label-inconsistent use of sibutramine in spontaneous adverse drug reaction reports in Germany.

Journal: International journal of clinical pharmacology and therapeutics 20080701

Title: Electrophysiological safety of sibutramine HCl.

Journal: Human & experimental toxicology 20080701

Title: Who will lose weight on sibutramine and orlistat? Psychological correlates for treatment success.

Journal: Diabetes, obesity & metabolism 20080601

Title: Orlistat and sibutramine beyond weight loss.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20080601

Title: Use of sibutramine to assist obese women with weight loss can be successful in dietitian-led clinics: another tool in the dietitian's toolbox.

Journal: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 20080601

Title: Sibutramine: balancing weight loss benefit and possible cardiovascular risk.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20080601

Title: Pharmacotherapy for obesity in menopausal women.

Journal: Menopause international 20080601

Title: Metformin plus sibutramine for olanzapine-associated weight gain and metabolic dysfunction in schizophrenia: a 12-week double-blind, placebo-controlled pilot study.

Journal: Psychiatry research 20080530

Title: Effect of sibutramine on weight reduction in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial.

Journal: Fertility and sterility 20080501

Title: Peripheral endocannabinoid system activity in patients treated with sibutramine.

Journal: Obesity (Silver Spring, Md.) 20080501

Title: [Sibutramine associated psychotic episode: a case report].

Journal: Revista medica de Chile 20080501

Title: Sibutramine-associated psychosis (case report).

Journal: Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20080501

Title: Effect of hypocaloric diet plus sibutramine treatment on hormonal and metabolic features in overweight and obese women with polycystic ovary syndrome: a randomized, 24-week study.

Journal: International journal of obesity (2005) 20080401

Title: Sympathetic-leptin relationship in obesity: effect of weight loss.

Journal: Metabolism: clinical and experimental 20080401

Title: Development and validation of high performance liquid chromatography method for analysis of sibutramine hydrochloride and its impurity.

Journal: Pakistan journal of pharmaceutical sciences 20080401

Title: [Pharmacological therapy of obesity].

Journal: Giornale italiano di cardiologia (2006) 20080401

Title: Long-term effects of weight-reducing interventions in hypertensive patients: systematic review and meta-analysis.

Journal: Archives of internal medicine 20080324

Title: Effects of sibutramine and orlistat on mood in obese and overweight subjects: a randomised study.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20080301

Title: Another dangerous combination for hypoglycemic coma: concurrent use of sibutramine and lorazepam.

Journal: QJM : monthly journal of the Association of Physicians 20080301

Title: Oral administration of the antiobesity drugs, sibutramine and rimonabant, increases acetylcholine efflux selectively in the medial prefrontal cortex of the rat.

Journal: Molecular psychiatry 20080301

Title: A novel promoter polymorphism in the human gene GNAS affects binding of transcription factor upstream stimulatory factor 1, Galphas protein expression and body weight regulation.

Journal: Pharmacogenetics and genomics 20080201

Title: Effects of sibutramine on gastric emptying, intestinal motility and rectal tone in dogs.

Journal: Digestive diseases and sciences 20080101

Title: Psychopathology in the context of obesity: the adiponectin hypothesis.

Journal: Medical hypotheses 20080101

Title: The development of tolerance to drugs that suppress food intake.

Journal: Pharmacology & therapeutics 20080101

Title: Efficacy of sibutramine for the treatment of binge eating disorder: a randomized multicenter placebo-controlled double-blind study.

Journal: The American journal of psychiatry 20080101

Title: [Pharmacotherapy of obesity].

Journal: Der Internist 20080101

Title: Catatonia and psychosis associated with sibutramine: a case report and pathophysiologic correlation.

Journal: Journal of psychosomatic research 20080101

Title: Binge eating disorder: the search for better treatments.

Journal: The American journal of psychiatry 20080101

Title: Successful treatment of a morbidly obese and growth-retarded adolescent with Williams-Beuren Syndrome by combining the medication of growth hormone and sibutramine.

Journal: Singapore medical journal 20080101

Title: Obesity: a review of pathogenesis and management strategies.

Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20080101

Title: Emerging concepts in the medical and surgical treatment of obesity.

Journal: Frontiers of hormone research 20080101

Title: The effect of sibutramine intake on resting and exercise physiological responses.

Journal: Annals of nutrition & metabolism 20080101

Title: [Study on the interaction of serum albumin and micromolecule compounds by modified fluorescence spectra].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20080101

Title: Effect of isocaloric diets and sibutramine on food intake, body mass variation and serum TNF-alpha levels in rats.

Journal: Pharmacology 20080101

Title: Development and validation of sensitive methods for determination of sibutramine hydrochloride monohydrate and direct enantiomeric separation on a protein-based chiral stationary phase.

Journal: Journal of AOAC International 20080101

Title: Fundamentals of cardiometabolic risk factor reduction: achieving and maintaining weight loss with pharmacotherapy or bariatric surgery.

Journal: Clinical cornerstone 20080101

Title: The endocannabinoid system as a target for obesity treatment.

Journal: Clinical cornerstone 20080101

Title: Cardiovascular responses to weight management and sibutramine in high-risk subjects: an analysis from the SCOUT trial.

Journal: European heart journal 20071201

Title: Sibutramine in cardiovascular disease: is SCOUT the new STORM on the horizon?

Journal: European heart journal 20071201

Title: Sibutramine and psychosis.

Journal: Journal of clinical psychopharmacology 20071201

Title: Pharmacotherapy for obesity.

Journal: Current atherosclerosis reports 20071201

Title: [Effect of weight loss on blood pressure].

Journal: MMW Fortschritte der Medizin 20071129

Title: [Antiobesity drugs--new limitations].

Journal: Revue medicale suisse 20071128

Title: Sibutramine usage in New Zealand: an analysis of prescription data by the Intensive Medicines Monitoring Programme.

Journal: Pharmacoepidemiology and drug safety 20071101

Title: Impact sibutramine therapy in children with hypothalamic obesity or obesity with aggravating syndromes.

Journal: The Journal of clinical endocrinology and metabolism 20071101

Title: The obese older female patient: CV risk and the SCOUT study.

Journal: International journal of obesity (2005) 20071101

Title: Myocardial infarction induced by appetite suppressants in Malaysia.

Journal: The New England journal of medicine 20071101

Title: The safety profiles of orlistat and sibutramine: results of prescription-event monitoring studies in England.

Journal: Obesity (Silver Spring, Md.) 20071101

Title: [Obesity: a review of currently used antiobesity drugs and new compounds in clinical development].

Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20071019

Title: [Obesity in adults].

Journal: Praxis 20071017

Title: Long-term persistence with orlistat and sibutramine in a population-based cohort.

Journal: International journal of obesity (2005) 20071001

Title: Drugs in the treatment of obesity: sibutramine, orlistat and rimonabant.

Journal: Public health nutrition 20071001

Title: Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up.

Journal: Journal of the American Dietetic Association 20071001

Title: Cardiovascular effects of sibutramine.

Journal: Pediatrics 20071001

Title: Strategies to reduce vascular risk associated with obesity.

Journal: Current vascular pharmacology 20071001

Title: Impact of weight loss on the metabolic syndrome.

Journal: International journal of obesity (2005) 20070901

Title: The obesity pandemic--how did we get here?

Journal: The Annals of pharmacotherapy 20070901

Title: Pharmacotherapeutic options for overweight adolescents.

Journal: The Annals of pharmacotherapy 20070901

Title: [Pharmacotherapy for weight loss in patients with type 2 diabetes].

Journal: Ugeskrift for laeger 20070813

Title: Pharmacogenomics and serotonergic agents: research observations and potential clinical practice implications.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070801

Title: NPY5R antagonism does not augment the weight loss efficacy of orlistat or sibutramine.

Journal: Obesity (Silver Spring, Md.) 20070801

Title: Alteration of gastric functions and candidate genes associated with weight reduction in response to sibutramine.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070701

Title: Cardiovascular effects of sibutramine in the treatment of obese adolescents: results of a randomized, double-blind, placebo-controlled study.

Journal: Pediatrics 20070701

Title: The cost-effectiveness of sibutramine in non-diabetic obese patients: evidence from four Western countries.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20070701

Title: National trends in the use and costs of anti-obesity medications in England 1998-2005.

Journal: Journal of public health (Oxford, England) 20070601

Title: Psychosis with sibutramine.

Journal: Journal of clinical psychopharmacology 20070601

Title: A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders.

Journal: Bipolar disorders 20070601

Title: Adulteration of over-the-counter slimming products with pharmaceutical analogue--an emerging threat.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20070601

Title: Sibutramine plus meal replacement therapy for body weight loss and maintenance in obese patients.

Journal: Obesity (Silver Spring, Md.) 20070601

Title: Open channel block of A-type, kv4.3, and delayed rectifier K+ channels, Kv1.3 and Kv3.1, by sibutramine.

Journal: The Journal of pharmacology and experimental therapeutics 20070501

Title: Drug treatment of the overweight patient.

Journal: Gastroenterology 20070501

Title: Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.

Journal: Circulation 20070417

Title: The obese hypertensive: the weight of evidence against beta-blockers.

Journal: Circulation 20070417

Title: [New therapeutic aspects for the control of risk factors in obesity].

Journal: Medicina clinica 20070407

Title: Placebo response in binge eating disorder.

Journal: The International journal of eating disorders 20070401

Title: The effect of sibutramine on energy expenditure and body composition in obese adolescents.

Journal: The Journal of clinical endocrinology and metabolism 20070401

Title: Sympathetic vasomotor tone determines blood pressure response to long-term sibutramine treatment.

Journal: The Journal of clinical endocrinology and metabolism 20070401

Title: Therapeutic options for modifying cardiometabolic risk factors.

Journal: The American journal of medicine 20070301

Title: Acute effects of sibutramine administration on the autonomic nervous system in obese subjects.

Journal: Clinical pharmacology and therapeutics 20070301

Title: [Childhood obesity. Recommendations of the Nutrition Committee of the Spanish Association of Pediatrics. Part II. Diagnosis. Comorbidities. Treatment].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20070301

Title: Weight management for type 2 diabetes mellitus: global cardiovascular risk reduction.

Journal: The American journal of cardiology 20070219

Title: Incorrect use of orlistat and sibutramine in clinical practice.

Journal: European journal of clinical pharmacology 20070201

Title: A double-blind, placebo-controlled trial of sibutramine for clozapine-associated weight gain.

Journal: Acta psychiatrica Scandinavica 20070201

Title: Rapid and sensitive method for the determination of sibutramine active metabolites in human plasma by reversed-phase liquid chromatography-tandem mass spectroscopy.

Journal: Journal of chromatographic science 20070201

Title: Exposure to sibutramine during pregnancy.

Journal: Canadian family physician Medecin de famille canadien 20070201

Title: Drug treatments for obesity: orlistat, sibutramine, and rimonabant.

Journal: Lancet (London, England) 20070106

Title: The effect of sibutramine-assisted weight loss in men with obstructive sleep apnoea.

Journal: International journal of obesity (2005) 20070101

Title: The obesity epidemic: current and future pharmacological treatments.

Journal: Annual review of pharmacology and toxicology 20070101

Title: Phentermine, sibutramine and metformin could be used for the prevention and treatment of steroid-induced weight gain.

Journal: Medical hypotheses 20070101

Title: Detection of sibutramine administration: a gas chromatography/mass spectrometry study of the main urinary metabolites.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Detection of sibutramine, its two metabolites and one analogue in a herbal product for weight loss by liquid chromatography triple quadrupole mass spectrometry and time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Currently available drugs for the treatment of obesity: Sibutramine and orlistat.

Journal: Mini reviews in medicinal chemistry 20070101

Title: A sibutramine-induced delusional disorder relapse.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20070101

Title: Weight loss and quality of life improvement in obese subjects treated with sibutramine: a double-blind randomized multicenter study.

Journal: Annals of nutrition & metabolism 20070101

Title: [Patients with type III obesity given sibutramine 15 mg/day lose weight in amounts proportional to those in types I and II, but waist circumferences does not decrease proportionally].

Journal: Gaceta medica de Mexico 20070101

Title: Weight loss in obese African American and Caucasian adolescents: secondary analysis of a randomized clinical trial of behavioral therapy plus sibutramine.

Journal: The Journal of cardiovascular nursing 20070101

Title: Anti-obesity drug use before professional treatment in Taiwan.

Journal: Asia Pacific journal of clinical nutrition 20070101

Title: [Hazard for human health and life by unintentional use of synthetic sibutramine, which was sold as Chinese herbal product 'meizitanc'].

Journal: Przeglad lekarski 20070101

Title: [Side effects after the usage of Chinese dieting product Meizitanc].

Journal: Przeglad lekarski 20070101

Title: Anorexic effect of (R)-sibutramine: comparison with (RS)-sibutramine [corrected] and (S)-sibutramine.

Journal: Indian journal of physiology and pharmacology 20070101

Title: Comparison of the effects of sibutramine and orlistat on obese, poorly-controlled type 2 diabetic patients.

Journal: Chang Gung medical journal 20070101

Title: Comparison of lipid lowering effect of sibutramine in patients treated or not treated with statins--3 month follow-up.

Journal: Prague medical report 20070101

Title: Assessment of clinical and economic benefits of weight management with sibutramine in general practice in Germany.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20061201

Title: Sibutramine for obesity in adolescents.

Journal: Expert opinion on pharmacotherapy 20061201

Title: Metabolic syndrome treatment strategies.

Journal: Pharmacotherapy 20061201

Title: The sibutramine metabolite M2 improves muscle glucose uptake and reduces hepatic glucose output: preliminary data.

Journal: Diabetes & vascular disease research 20061201

Title: [Pharmacotherapy of obesity].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20061201

Title: Tolerability and effectiveness of fluoxetine, metformin and sibutramine in reducing anthropometric and metabolic parameters in obese patients.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20061201

Title: Comparison of orlistat and sibutramine in an obesity management program: efficacy, compliance, and weight regain after noncompliance.

Journal: Eating and weight disorders : EWD 20061201

Title: Locomotor and peripheral effects of sibutramine modulated by 5-HT2 receptors.

Journal: Canadian journal of physiology and pharmacology 20061201

Title: Reduced left ventricular mass after treatment of obese patients with sibutramine: An echocardiographic multicentre study.

Journal: Diabetes, obesity & metabolism 20061101

Title: Baseline serum folate level may be a predictive factor of weight loss in a morbid-obesity-management programme.

Journal: The British journal of nutrition 20061101

Title: The primary amine metabolite of sibutramine stimulates lipolysis in adipocytes isolated from lean and obese mice and in isolated human adipocytes.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20061101

Title: Serotonin and norepinephrine reuptake inhibition and eating behavior.

Journal: Annals of the New York Academy of Sciences 20061101

Title: Current and novel approaches to the drug therapy of obesity.

Journal: European journal of clinical pharmacology 20061001

Title: Identification of a sibutramine-metabolite in patient urine after intake of a 'pure herbal' Chinese slimming product.

Journal: Therapeutic drug monitoring 20061001

Title: Pharmacotherapy of obesity.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20061001

Title: Anorectic sibutramine detected in a Chinese herbal drug for weight loss.

Journal: Forensic science international 20060912

Title: Metabolite profile of sibutramine in human urine: a liquid chromatography-electrospray ionization mass spectrometric study.

Journal: Journal of mass spectrometry : JMS 20060901

Title: Bruising associated with sibutramine: results from postmarketing surveillance in New Zealand.

Journal: International journal of obesity (2005) 20060801

Title: Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats.

Journal: British journal of pharmacology 20060801

Title: Norepinephrine transporter inhibition prevents tilt-induced pre-syncope.

Journal: Journal of the American College of Cardiology 20060801

Title: Weight loss medications--where do they fit in?

Journal: Australian family physician 20060801

Title: Pharmacologic treatment for obesity. Options for today...and tomorrow.

Journal: Advance for nurse practitioners 20060801

Title: Peripheral mechanisms of sibutramine involving proximal gastric motility in dogs.

Journal: Obesity (Silver Spring, Md.) 20060801

Title: Summaries for patients. Effects of drug treatment for obesity in adolescence.

Journal: Annals of internal medicine 20060718

Title: Effects of sibutramine treatment in obese adolescents: a randomized trial.

Journal: Annals of internal medicine 20060718

Title: What constitutes successful weight management in adolescents?

Journal: Annals of internal medicine 20060718

Title: The obesity epidemic and its cardiovascular consequences.

Journal: Current opinion in cardiology 20060701

Title: Short-term sibutramine therapy is associated with weight loss and improved endothelial function in obese patients with coronary artery disease.

Journal: The American journal of cardiology 20060601

Title: Use of lifestyle changes treatment plans and drug therapy in controlling cardiovascular and metabolic risk factors.

Journal: Obesity (Silver Spring, Md.) 20060601

Title: Influence of weight reduction by sibutramine on female sexual function.

Journal: International journal of obesity (2005) 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Effect of sibutramine and of cognitive-behavioural weight loss therapy in obesity and subclinical binge eating disorder.

Journal: Diabetes, obesity & metabolism 20060501

Title: Influence of sibutramine treatment on sympathetic vasomotor tone in obese subjects.

Journal: Clinical pharmacology and therapeutics 20060501

Title: Use of sibutramine in obese mexican adolescents: a 6-month, randomized, double-blind, placebo-controlled, parallel-group trial.

Journal: Clinical therapeutics 20060501

Title: QT interval prolongation associated with sibutramine treatment.

Journal: British journal of clinical pharmacology 20060401

Title: Locomotion is the major determinant of sibutramine-induced increase in energy expenditure.

Journal: Pharmacology, biochemistry, and behavior 20060401

Title: Keeping weight-loss drugs in perspective. If you're dangerously overweight, diet pills may help--but not without major lifestyle changes.

Journal: Harvard women's health watch 20060401

Title: Pharmacological treatment of obesity.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20060401

Title: Chronic treatment with either dexfenfluramine or sibutramine in diet-switched diet-induced obese mice.

Journal: Endocrine 20060401

Title: [Pharmacotherapy in the treatment of obesity].

Journal: MMW Fortschritte der Medizin 20060302

Title: Neurochemical, neuroautonomic and neuropharmacological acute effects of sibutramine in healthy subjects.

Journal: Neurotoxicology 20060301

Title: Prediction of response to sibutramine therapy in obese non-diabetic and diabetic patients.

Journal: Diabetes, obesity & metabolism 20060301

Title: Clinical trial issues in weight-loss therapy.

Journal: American heart journal 20060301

Title: Weight loss as a treatment for nonalcoholic fatty liver disease.

Journal: Journal of clinical gastroenterology 20060301

Title: Effects of sibutramine on the appetitive and consummatory aspects of feeding in non-human primates.

Journal: Physiology & behavior 20060227

Title: Cardiovascular responses to melanocortin 4-receptor stimulation in conscious unrestrained normotensive rats.

Journal: Peptides 20060201

Title: Central nervous system biogenic amine targets for control of appetite and energy expenditure.

Journal: Endocrine 20060201

Title: [Spectroscopic studies on the binding of sibutramine hydrochloride and bovine serum albumin].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060201

Title: [Drug treatment of obesity].

Journal: Ugeskrift for laeger 20060109

Title: Pharmacotherapy for obesity.

Journal: Appetite 20060101

Title: Pharmacologic treatment of obesity.

Journal: Advances in psychosomatic medicine 20060101

Title: Sibutramine as an adjuvant therapy in adolescents suffering from morbid obesity.

Journal: The Israel Medical Association journal : IMAJ 20060101

Title: [Reducing obesity].

Journal: Presse medicale (Paris, France : 1983) 20060101

Title: Early first-trimester sibutramine exposure : pregnancy outcome and neonatal follow-up.

Journal: Drug safety 20060101

Title: Assessment and management of the obese adult female: a clinical update for providers.

Journal: Journal of midwifery & women's health 20060101

Title: Determination of N-desmethyl- and N-bisdesmethyl metabolites of Sibutramine in doping control analysis using liquid chromatography-tandem mass spectrometry.

Journal: European journal of mass spectrometry (Chichester, England) 20060101

Title: Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures.

Journal: The Annals of pharmacotherapy 20060101

Title: Emerging pharmacotherapy for treating obesity and associated cardiometabolic risk.

Journal: Asia Pacific journal of clinical nutrition 20060101

Title: Valuable lessons from research on drugs for adolescent obesity in Mexico.

Journal: Advances in therapy 20060101

Title: Liquid chromatography/electrospray ionization tandem mass spectrometry validated method for the simultaneous quantification of sibutramine and its primary and secondary amine metabolites in human plasma and its application to a bioequivalence study.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Medical management of obesity.

Journal: Acta clinica Belgica 20060101

Title: Effects of sibutramine on thermogenesis in obese patients assessed via immersion calorimetry.

Journal: Advances in therapy 20060101

Title: Obesity.

Journal: Annual review of clinical psychology 20060101

Title: Sibutramine therapy in obese women--effects on plasma neuropeptide Y (NPY), insulin, leptin and beta-endorphin concentrations.

Journal: Neuro endocrinology letters 20051201

Title: Serotonin syndrome and the anaesthetist.

Journal: Anaesthesia and intensive care 20051201

Title: Randomized trial of lifestyle modification and pharmacotherapy for obesity.

Journal: The New England journal of medicine 20051117

Title: Pharmacotherapy for obesity--promise and uncertainty.

Journal: The New England journal of medicine 20051117

Title: Sibutramine use associated with reversible hepatotoxicity.

Journal: Annals of internal medicine 20051115

Title: Rapid treatment of posttraumatic stress disorder with sibutramine.

Journal: Epilepsy & behavior : E&B 20051101

Title: Pharmacologic agents for the treatment of obesity.

Journal: Clinics in geriatric medicine 20051101

Title: Trends in obesity and overweight-related office visits and drug prescriptions in Canada, 1998 to 2004.

Journal: Obesity research 20051101

Title: Sibutramine in pregnancy.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20051001

Title: Efficacy and safety of sibutramine in 2225 subjects with cardiovascular risk factors: short-term, open-label, observational study.

Journal: Journal of human hypertension 20050901

Title: Sibutramine does not worsen sleep apnea syndrome: a randomized double-blind placebo-controlled study.

Journal: Sleep medicine 20050901

Title: New options for drug treatment of obesity in patients with Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050901

Title: Childhood obesity. Treatment options.

Journal: Best practice & research. Clinical endocrinology & metabolism 20050901

Title: [Effects of sibutramine on blood glucose and lipids, body fat mass and insulin resistance in obese patients: a multi-center clinical trial].

Journal: Zhonghua nei ke za zhi 20050901

Title: New drug policy in childhood obesity.

Journal: International journal of obesity (2005) 20050901

Title: Sibutramine improves insulin sensitivity without alteration of serum adiponectin in obese subjects with Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050801

Title: Long-term maintenance of weight loss with sibutramine in a GP setting following a specialist guided very-low-calorie diet: a double-blind, placebo-controlled, parallel group study.

Journal: European journal of clinical nutrition 20050801

Title: Effects of sibutramine in overweight, poorly controlled Chinese female type 2 diabetic patients: a randomised, double-blind, placebo-controlled study.

Journal: International journal of clinical practice 20050701

Title: Control of diastereoselectivity by solvent effects in the addition of Grignard reagents to enantiopure t-butylsulfinimine: syntheses of the stereoisomers of the hydroxyl derivatives of sibutramine.

Journal: Organic letters 20050623

Title: Two-year outcome of a combination of weight loss therapies for type 2 diabetes.

Journal: Diabetes care 20050601

Title: Sibutramine and the sympathetic nervous system in obese humans.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20050601

Title: Paradoxical effect of sibutramine on autonomic cardiovascular regulation in obese hypertensive patients--sibutramine and blood pressure.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20050601

Title: Obesity.

Journal: Clinical evidence 20050601

Title: Influence of Sibutramine on blood pressure: evidence from placebo-controlled trials.

Journal: International journal of obesity (2005) 20050501

Title: Effects of sibutramine on abdominal fat mass, insulin resistance and blood pressure in obese hypertensive patients.

Journal: Diabetes, obesity & metabolism 20050501

Title: A double-blind, placebo-controlled trial of sibutramine for olanzapine-associated weight gain.

Journal: The American journal of psychiatry 20050501

Title: Effects of oleoyl-estrone with dexfenfluramine, sibutramine or phentermine on overweight rats.

Journal: European journal of pharmacology 20050425

Title: Effect of sibutramine on weight management and metabolic control in type 2 diabetes: a meta-analysis of clinical studies.

Journal: Diabetes care 20050401

Title: Pharmacological treatments for obesity.

Journal: Professional nurse (London, England) 20050401

Title: Obesity and cardiovascular physiology: impact of some pharmacological agents.

Journal: Current vascular pharmacology 20050401

Title: [Obesity pharmacological treatment].

Journal: Revista clinica espanola 20050401

Title: [Evaluation of the sibutramine effect on satiety with a visual analogue scale in obese adolescents].

Journal: Arquivos brasileiros de endocrinologia e metabologia 20050401

Title: Sibutramine: possible cause of a reversible cardiomyopathy.

Journal: International journal of cardiology 20050330

Title: Disconnection between the early onset anorectic effects by C75 and hypothalamic fatty acid synthase inhibition in rodents.

Journal: European journal of pharmacology 20050321

Title: Treatment of obese adolescents with sibutramine: a randomized, double-blind, controlled study.

Journal: The Journal of clinical endocrinology and metabolism 20050301

Title: Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity.

Journal: Current drug targets 20050301

Title: The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes.

Journal: The Journal of pharmacy and pharmacology 20050301

Title: A review of the metabolic effects of sibutramine.

Journal: Current medical research and opinion 20050301

Title: Clinical evidence for drug treatments in obesity-associated hypertensive patients--a discussion paper.

Journal: Methods and findings in experimental and clinical pharmacology 20050301

Title: Safety pharmacology of sibutramine mesylate, an anti-obesity drug.

Journal: Human & experimental toxicology 20050301

Title: [Obesity and metabolic syndrome: clinical and therapeutic review].

Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20050301

Title: Psychobehavioral and nutritional predictors of weight loss in obese women treated with sibutramine.

Journal: International journal of obesity (2005) 20050201

Title: Sibutramine treatment in obesity: initial eating behaviour in relation to weight loss results and changes in mood.

Journal: Pharmacological research 20050201

Title: Effects of sibutramine-induced weight loss on cardiovascular system in obese subjects.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20050201

Title: Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus.

Journal: The Cochrane database of systematic reviews 20050125

Title: Efficacy and safety comparative evaluation of orlistat and sibutramine treatment in hypertensive obese patients.

Journal: Diabetes, obesity & metabolism 20050101

Title: Does prior authorization of sibutramine improve medication compliance or weight loss?

Journal: Obesity research 20050101

Title: Use of sibutramine, an inhibitor of the reuptake of serotonin and noradrenaline, in the treatment of binge eating disorder: a placebo-controlled study.

Journal: Advances in therapy 20050101

Title: Cost-effectiveness of sibutramine in the LOSE Weight Study: evaluating the role of pharmacologic weight-loss therapy within a weight management program.

Journal: Journal of managed care pharmacy : JMCP 20050101

Title: Effect of sibutramine on blood pressure in patients with obesity and well-controlled hypertension or normotension.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20050101

Title: Pharmacotherapy to reduce visceral fat.

Journal: Clinical cornerstone 20050101

Title: Use of sibutramine in obese Hispanic adolescents.

Journal: Advances in therapy 20050101

Title: [The 'problem obesity': viewpoint of the internist].

Journal: Annali italiani di chirurgia 20050101

Title: Diets, drugs, exercise, and behavioral modification: Where these work and where they do not.

Journal: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 20050101

Title: Sibutramine may be associated with memory impairment.

Journal: BMJ (Clinical research ed.) 20041204

Title: Modern, new pharmacotherapy for obesity. A gastrointestinal approach.

Journal: Best practice & research. Clinical gastroenterology 20041201

Title: Sibutramine improves fat distribution and insulin resistance, and increases serum adiponectin levels in Korean obese nondiabetic premenopausal women.

Journal: Diabetes research and clinical practice 20041201

Title: Efficacy of sibutramine, orlistat and combination therapy on short-term weight management in obese patients.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20041201

Title: Medical management of obesity in women: office-based approaches to weight management.

Journal: Clinical obstetrics and gynecology 20041201

Title: Sibutramine in the treatment of obesity in type 2 diabetic patients and in nondiabetic subjects.

Journal: Acta diabetologica 20041201

Title: Long-term pharmacotherapy for obesity.

Journal: Obesity research 20041201

Title: Relative bioavailability and pharmacokinetics of a new sibutramine formulation in healthy male subjects: a randomized, open-label, two-period, comparative crossover study.

Journal: Clinical therapeutics 20041201

Title: A pilot study to evaluate the pharmacokinetics of sibutramine in healthy subjects under fasting and fed conditions.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20041112

Title: Effects of sibutramine on anxiety-related behaviours in rats.

Journal: Pharmacological research 20041101

Title: Combined dietary and pharmacological weight management in obese hypopituitary patients.

Journal: Obesity research 20041101

Title: [Sibutramin in obesity treatment (multicenter, open, prospective 12-month-long study)].

Journal: Vnitrni lekarstvi 20041101

Title: [Pharmacotherapy of obesity].

Journal: Ugeskrift for laeger 20041018

Title: Clinical pharmacotherapy for obesity: current drugs and those in advanced development.

Journal: Current drug targets 20041001

Title: Quantitative body composition analysis in awake mice and rats by magnetic resonance relaxometry.

Journal: Obesity research 20041001

Title: A perspective on the current strategies for the treatment of obesity.

Journal: Current drug targets. CNS and neurological disorders 20041001

Title: Treatment effect of sibutramine compared to fluoxetine on leptin levels in polycystic ovary disease.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20041001

Title: Exposure to sibutramine during pregnancy: a case series.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20040910

Title: Use of sibutramine in overweight adult hispanic patients with type 2 diabetes mellitus: a 12-month, randomized, double-blind, placebo-controlled clinical trial.

Journal: Clinical therapeutics 20040901

Title: [A multicenter and open study on efficacy and safety of sibutramine in obese subjects].

Journal: Zhonghua yi xue za zhi 20040802

Title: Sibutramine use in pregnancy: report of two cases.

Journal: Birth defects research. Part A, Clinical and molecular teratology 20040801

Title: The novel antiobesic HMR1426 reduces food intake without affecting energy expenditure in rats.

Journal: Obesity research 20040801

Title: Comparison of the acute pharmacodynamic responses after single doses of ephedrine or sibutramine in healthy, overweight volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20040801

Title: Comparison of metabolic effects of orlistat and sibutramine treatment in Type 2 diabetic obese patients.

Journal: Diabetes, nutrition & metabolism 20040801

Title: Efficacy of pharmacotherapy for weight loss in adults with type 2 diabetes mellitus: a meta-analysis.

Journal: Archives of internal medicine 20040712

Title: [Pharmacotherapy of obesity].

Journal: Wiener medizinische Wochenschrift (1946) 20040701

Title: Pharmacological and surgical treatment of obesity.

Journal: Evidence report/technology assessment (Summary) 20040701

Title: The Long-term Outcomes of Sibutramine Effectiveness on Weight (LOSE Weight) study: evaluating the role of drug therapy within a weight management program in a group-model health maintenance organization.

Journal: The American journal of managed care 20040601

Title: Prediction of successful weight reduction under sibutramine therapy.

Journal: Pharmacogenetics 20040601

Title: [Binge eating disorder: an emerging entity that responds to pharmacotherapy].

Journal: Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20040601

Title: [Sibutramine administration in polycystic ovary syndrome treatment].

Journal: Ginekologia polska 20040601

Title: Croatian experience with sibutramine in the treatment of obesity--multicenter prospective study.

Journal: Collegium antropologicum 20040601

Title: Obesity.

Journal: Clinical evidence 20040601

Title: The efficacy and safety of sibutramine for weight loss: a systematic review.

Journal: Archives of internal medicine 20040510

Title: Systematic review of the long-term effects and economic consequences of treatments for obesity and implications for health improvement.

Journal: Health technology assessment (Winchester, England) 20040501

Title: Comparison of efficacy of sibutramine or orlistat versus their combination in obese women.

Journal: Endocrine research 20040501

Title: [Sustained weight reduction after cessation of obesity treatment with Sibutramine].

Journal: Deutsche medizinische Wochenschrift (1946) 20040430

Title: Health-related quality of life in a randomised placebo-controlled trial of sibutramine in obese patients with type II diabetes.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040401

Title: Food intake with an antiobesity drug (sibutramine) versus placebo and rorschach data: a crossover within-subjects study.

Journal: Journal of personality assessment 20040401

Title: Modest weight loss and reduction in waist circumference after medical treatment are associated with favorable changes in serum adipocytokines.

Journal: Metabolism: clinical and experimental 20040401

Title: Weight reduction by sibutramine in obese subjects in primary care medicine: the SAT Study.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20040401

Title: The effect of 1-yr sibutramine treatment on glucose tolerance, insulin sensitivity and serum lipid profiles in obese subjects.

Journal: Diabetes, nutrition & metabolism 20040401

Title: Acute cardiovascular effects of sibutramine in conscious rats.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: Effect of low-dose metoprolol in combination with sibutramine therapy in normotensive obese patients: a randomized controlled study.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040301

Title: 5-HT has contrasting effects in the frontal cortex, but not the hypothalamus, on changes in noradrenaline efflux induced by the monoamine releasing-agent, d-amphetamine, and the reuptake inhibitor, BTS 54 354.

Journal: Neuropharmacology 20040301

Title: Sibutramine and the management of obesity.

Journal: Expert opinion on pharmacotherapy 20040301

Title: Orlistat, sibutramine, or combination therapy: which performs better on waist circumference in relation with body mass index in obese patients?

Journal: The Tohoku journal of experimental medicine 20040301

Title: [Studies of the effects of sibutramine hydrochloride on perinatal development and maternal function in mice].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040301

Title: Sibutramine induces potential-dependent exocytotic release but not carrier-mediated release of dopamine and 5-hydroxytryptamine.

Journal: European journal of pharmacology 20040126

Title: [Struggle about the best reducing diet, Fat gone by means of more fat?].

Journal: MMW Fortschritte der Medizin 20040115

Title: Effects of the sibutramine therapy on pulmonary artery pressure in obese patients.

Journal: Diabetes, obesity & metabolism 20040101

Title: Obesity management in patients with type 2 diabetes mellitus.

Journal: Mymensingh medical journal : MMJ 20040101

Title: What role for weight-loss medication? Weighing the pros and cons for obese patients.

Journal: Postgraduate medicine 20040101

Title: Clinical use of sibutramine.

Journal: Drugs of today (Barcelona, Spain : 1998) 20040101

Title: Cost-effectiveness of sibutramine in the treatment of obesity.

Journal: Medical decision making : an international journal of the Society for Medical Decision Making 20040101

Title: [Sibutramine in treatment of obesity. Therapeutic premises in patients with essential hypertension, diabetes, hyperlipidemia].

Journal: Przeglad lekarski 20040101

Title: Long-term pharmacotherapy for obesity and overweight.

Journal: The Cochrane database of systematic reviews 20040101

Title: [Pharmacological treatment of obesity].

Journal: Revista de medicina de la Universidad de Navarra 20040101

Title: Metformin versus sibutramine in the treatment of hyperinsulinemia in chronically anovulating women.

Journal: Bratislavske lekarske listy 20040101

Title: [Pharmacological treatment for obesity].

Journal: Gaceta medica de Mexico 20040101

Title: Managing type 2 diabetes mellitus in patients with obesity.

Journal: Treatments in endocrinology 20040101

Title: Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized controlled trials.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20031201

Title: Great expectations: 'I'm losing 25% of my weight no matter what you say'.

Journal: Journal of consulting and clinical psychology 20031201

Title: Obesity and pharmacologic therapy.

Journal: Endocrinology and metabolism clinics of North America 20031201

Title: Obesity.

Journal: Clinical evidence 20031201

Title: [Serum leptin and insulin resistance in obesity and effects of sibutramine on them].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20031201

Title: [Effectiveness of therapeutic interventions in obesity].

Journal: Praxis 20031119

Title: Sibutramine has a positive effect on clinical and metabolic parameters in obese patients with polycystic ovary syndrome.

Journal: Fertility and sterility 20031101

Title: A randomized, double-blind, placebo-controlled study of sibutramine in the treatment of binge-eating disorder.

Journal: Archives of general psychiatry 20031101

Title: Sibutramine treatment in obesity: predictors of weight loss including rorschach personality data.

Journal: Obesity research 20031101

Title: Effect of sibutramine on macronutrient selection in male and female rats.

Journal: Physiology & behavior 20031101

Title: Pharmacokinetics of sibutramine hydrochloride in Chinese healthy volunteers.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20031101

Title: [New therapeutic options in obesity].

Journal: MMW Fortschritte der Medizin 20031016

Title: The implementation of nutritional advice for people with diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20031001

Title: Advances in eating disorders offer food for thought.

Journal: JAMA 20030917

Title: Management of the overweight patient with Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20030901

Title: Sibutramine enhances insulin sensitivity ameliorating metabolic parameters in a double-blind, randomized, placebo-controlled trial.

Journal: Diabetes, obesity & metabolism 20030901

Title: Effect of sibutramine on weight loss and blood pressure: a meta-analysis of controlled trials.

Journal: Obesity research 20030901

Title: The effects of sibutramine and orlistat on the ultrasonographic findings, insulin resistance and liver enzyme levels in obese patients with non-alcoholic steatohepatitis.

Journal: Romanian journal of gastroenterology 20030901

Title: Prediction of successful weight reduction under sibutramine therapy through genotyping of the G-protein beta3 subunit gene (GNB3) C825T polymorphism.

Journal: Pharmacogenetics 20030801

Title: Sibutramine in the management of obesity.

Journal: The Journal of family practice 20030801

Title: Sibutramine sensitivity assay revealed a unique phenotype of bombesin BB3 receptor-deficient mice.

Journal: European journal of pharmacology 20030718

Title: [What effect does losing weight have on hypertension?].

Journal: MMW Fortschritte der Medizin 20030710

Title: Interaction between sibutramine and cyclosporine.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030701

Title: Severe bullous drug eruption due to sibutramine (Reductil).

Journal: The British journal of dermatology 20030701

Title: Postmarketing surveillance for drug abuse.

Journal: Drug and alcohol dependence 20030605

Title: Pharmacological therapy of obesity: past, present, and future.

Journal: The Journal of clinical endocrinology and metabolism 20030601

Title: Short-term effects of sibutramine (Reductil) on appetite and eating behaviour and the long-term therapeutic outcome.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20030601

Title: Health risks, past usage, and intention to use weight loss products in normal weight women with high and low body dysphoria.

Journal: Eating and weight disorders : EWD 20030601

Title: Use of sibutramine to treat obesity.

Journal: Primary care 20030601

Title: Potential for sibutramine-yohimbine interaction?

Journal: Lancet (London, England) 20030524

Title: [A drug help in reducing? Risk profile decides whether and how].

Journal: MMW Fortschritte der Medizin 20030522

Title: [Abuse potential of sibutramine].

Journal: Medicina clinica 20030503

Title: Effects of sibutramine on binge eating, hunger, and fullness in a laboratory human feeding paradigm.

Journal: Obesity research 20030501

Title: Experimental drugs take aim at obesity.

Journal: JAMA 20030409

Title: Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial.

Journal: JAMA 20030409

Title: Preferential effects of the cannabinoid CB1 receptor antagonist, SR 141716, on food intake and body weight gain of obese (fa/fa) compared to lean Zucker rats.

Journal: Psychopharmacology 20030401

Title: Sibutramine decreases body weight gain and increases energy expenditure in obese Zucker rats without changes in NPY and orexins.

Journal: Nutritional neuroscience 20030401

Title: Effects of preexposure to dexfenfluramine, phentermine, dexfenfluramine-phentermine, or fluoxetine on sibutramine-induced hypophagia in the adult rat.

Journal: Pharmacology, biochemistry, and behavior 20030401

Title: [Overweight patient has tried many times to lose weight. What helps against stubborn fat padding?].

Journal: MMW Fortschritte der Medizin 20030306

Title: Determination of the active metabolite of sibutramine by liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305

Title: Postmarketing surveillance of abuse liability of sibutramine.

Journal: Drug and alcohol dependence 20030301

Title: Phenylethanolamine N-methyltransferase G-148A genetic variant and weight loss in obese women.

Journal: Obesity research 20030301

Title: Ask the doctor. I took the diet drug sibutramine (Meridia) for two months but stopped when I heard that its use had been linked to some deaths. During this time I developed mitral valve regurgitation. Could this have been a side effect of Meridia?

Journal: Harvard heart letter : from Harvard Medical School 20030301

Title: [Weight loss via drug therapy].

Journal: Der Internist 20030301

Title: Obesity drug pipeline not so fat.

Journal: Science (New York, N.Y.) 20030207

Title: Medical management of obesity: a clinical imperative?

Journal: Current diabetes reports 20030201

Title: A randomized trial of sibutramine in the management of obese type 2 diabetic patients treated with metformin.

Journal: Diabetes care 20030101

Title: Bombesin receptor subtype-3 modulates plasma insulin concentration.

Journal: Peptides 20030101

Title: Obesity.

Journal: Clinical medicine (London, England) 20030101

Title: Weight management and current options in pharmacotherapy: orlistat and sibutramine.

Journal: Clinical therapeutics 20030101

Title: Medical management of obesity: present and future therapy.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20030101

Title: Safety and efficacy of sibutramine in overweight Hispanic patients with hypertension.

Journal: Advances in therapy 20030101

Title: A benefit-risk assessment of sibutramine in the management of obesity.

Journal: Drug safety 20030101

Title: Long-term pharmacotherapy for obesity and overweight.

Journal: The Cochrane database of systematic reviews 20030101

Title: Sibutramine: its mode of action and efficacy.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20021201

Title: Metabolic benefits associated with sibutramine therapy.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20021201

Title: Sibutramine and its cardiovascular profile.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20021201

Title: Pharmacotherapy of obesity.

Journal: Best practice & research. Clinical endocrinology & metabolism 20021201

Title: Pharmacological management of obesity.

Journal: Expert opinion on pharmacotherapy 20021201

Title: New antiobesity agents in type 2 diabetes: overview of clinical trials with sibutramine and orlistat.

Journal: Diabetes & metabolism 20021201

Title: First application of tunable alkyl or aryl sulfinamides to the stereoselective synthesis of a chiral amine: asymmetric synthesis of (R)-didesmethylsibutramine ((R)-DDMS) using (R)-triethylmethylsulfinamide ((R)-TESA).

Journal: Organic letters 20021114

Title: Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia.

Journal: Organic letters 20021114

Title: Paradoxical effect of sibutramine on autonomic cardiovascular regulation.

Journal: Circulation 20021105

Title: The new role of pharmacotherapy for weight reduction in obesity.

Journal: International journal of clinical practice 20021101

Title: New pharmacological tools for obesity.

Journal: Journal of endocrinological investigation 20021101

Title: Add-on combination and maintenance treatment: case series of five obese patients with different eating behavior.

Journal: Journal of clinical psychopharmacology 20021001

Title: Sibutramine and panic attacks.

Journal: The American journal of psychiatry 20021001

Title: Sibutramine for compulsive eating in hypothalamic deficiency.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 20021001

Title: Major depressive episodes and diet pills.

Journal: Expert opinion on pharmacotherapy 20021001

Title: Effectiveness of sibutramine.

Journal: The Journal of family practice 20021001

Title: Comparison of the thermogenic and hypophagic effects of sibutramine's metabolite 2 and other monoamine reuptake inhibitors.

Journal: European journal of pharmacology 20020927

Title: [Cardiac safety and sibutramine].

Journal: Medicina clinica 20020921

Title: [Weight loss lowers blood pressure, lipids and blood glucose. Sibutramine also helps diabetics with weight loss].

Journal: MMW Fortschritte der Medizin 20020912

Title: Mechanism of the thermogenic effect of Metabolite 2 (BTS 54 505), a major pharmacologically active metabolite of the novel anti-obesity drug, sibutramine.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20020901

Title: Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction.

Journal: American heart journal 20020901

Title: Treatment of fibromyalgia with sibutramine hydrochloride monohydrate: comment on the article by Goldenberg et al.

Journal: Arthritis and rheumatism 20020901

Title: Sibutramine-induced mania episode in a bipolar patient.

Journal: The international journal of neuropsychopharmacology 20020901

Title: Sibutramine lost and found.

Journal: Eating and weight disorders : EWD 20020901

Title: Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats.

Journal: Diabetes 20020801

Title: Drugs under investigation for attention-deficit hyperactivity disorder.

Journal: Current opinion in investigational drugs (London, England : 2000) 20020801

Title: [The anti-obesity drug sibutramine for overweight diabetic patients. 'Blood pressure is not elevated')].

Journal: MMW Fortschritte der Medizin 20020711

Title: Options for pharmacological management of obesity in patients treated with atypical antipsychotics.

Journal: International clinical psychopharmacology 20020701

Title: Combining behavioral and pharmacological treatments for obesity.

Journal: Obesity research 20020601

Title: Sibutramine warning: hypertension and cardiac arrhythmias reported.

Journal: Obesity surgery 20020601

Title: Obesity drug sibutramine (Meridia): hypertension and cardiac arrhythmias.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020514

Title: [Extra pounds despite sports and diets. Genetics can also be involved].

Journal: MMW Fortschritte der Medizin 20020509

Title: I have tried everything I can think of to lose weight on my own and am now thinking of using weight-loss medications. Are they safe?

Journal: Heart advisor 20020501

Title: The discovery and status of sibutramine as an anti-obesity drug.

Journal: European journal of pharmacology 20020412

Title: The cerebrospinal fluid/serum leptin ratio during pharmacological therapy for obesity.

Journal: The Journal of clinical endocrinology and metabolism 20020401

Title: [Anti-obesity drugs: sibutramine and orlistat].

Journal: Medicina clinica 20020330

Title: [Treatment of obesity in practice - more necessary than ever].

Journal: Deutsche medizinische Wochenschrift (1946) 20020322

Title: [Sibutramine in clinical practice - a PMS-study with positive effects on blood pressure and metabolic parameters].

Journal: Deutsche medizinische Wochenschrift (1946) 20020322

Title: Regulation of body weight and carcass composition by sibutramine in rats.

Journal: Obesity research 20020301

Title: Sibutramine-dependent brown fat activation in rats: an immunohistochemical study.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20020301

Title: Can drugs help you lose weight?

Journal: Harvard heart letter : from Harvard Medical School 20020301

Title: Pharmacotherapy for obesity: a quantitative analysis of four decades of published randomized clinical trials.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20020201

Title: Organic hypomania secondary to sibutramine-citalopram interaction.

Journal: The Journal of clinical psychiatry 20020201

Title: Role of sibutramine in the treatment of obese Type 2 diabetic patients receiving sulphonylurea therapy.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20020201

Title: Effects of sibutramine on the treatment of obesity in patients with arterial hypertension.

Journal: Arquivos brasileiros de cardiologia 20020201

Title: Effects of sibutramine in non-dieting obese women.

Journal: Journal of endocrinological investigation 20020201

Title: [Study of heart valve function on obese patients treated with sibutramine].

Journal: Medicina clinica 20020126

Title: Risk factor modification through weight loss enhanced with pharmacotherapy.

Journal: Current atherosclerosis reports 20020101

Title: Measuring the effect of sibutramine for weight loss.

Journal: JAMA 20020101

Title: An open-label trial of sibutramine in obese patients with binge-eating disorder.

Journal: The Journal of clinical psychiatry 20020101

Title: Sibutramine and blood pressure: a therapeutic dilemma.

Journal: Journal of human hypertension 20020101

Title: Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors.

Journal: Journal of human hypertension 20020101

Title: Efficacy and safety of sibutramine for weight loss in obese patients with hypertension well controlled by beta-adrenergic blocking agents: a placebo-controlled, double-blind, randomised trial.

Journal: Journal of human hypertension 20020101

Title: Evaluation of the safety and efficacy of sibutramine, orlistat and metformin in the treatment of obesity.

Journal: Diabetes, obesity & metabolism 20020101

Title: The clinical effectiveness and cost-effectiveness of sibutramine in the management of obesity: a technology assessment.

Journal: Health technology assessment (Winchester, England) 20020101

Title: [Weight reduction. Antiobesity drug treatment in type-2 diabetics].

Journal: Pharmazie in unserer Zeit 20020101

Title: Evaluation of efficacy, reliability, and tolerability of sibutramine in obese patients, with an echocardiographic study.

Journal: Revista do Hospital das Clinicas 20020101

Title: Pharmacologic agents for weight reduction.

Journal: The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20020101

Title: Obesity, cardiovascular risk and pharmacotherapy.

Journal: Blood pressure 20020101

Title: [Obesity: gradual-schedule therapy and long-term results].

Journal: MMW Fortschritte der Medizin 20011213

Title: American College of Sports Medicine position stand. Appropriate intervention strategies for weight loss and prevention of weight regain for adults.

Journal: Medicine and science in sports and exercise 20011201

Title: Does long-term use of sibutramine (Meridia) result in continued weight loss in short-term responders?

Journal: The Journal of family practice 20011201

Title: Is sibutramine more than a slim hope?

Journal: Drug and therapeutics bulletin 20011201

Title: Sibutramine in clinical practice.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20011201

Title: When, for whom and how to use sibutramine?

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20011201

Title: Sibutramine in overweight/obese hypertensive patients.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20011201

Title: The importance of obesity in diabetes and its treatment with sibutramine.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20011201

Title: The role of sibutramine in weight management--towards a blueprint for a sibutramine weight management system.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20011201

Title: How does sibutramine work?

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20011201

Title: [Drugs for obesity. Why are obese patients diferent?].

Journal: Medicina clinica 20011103

Title: Effects of sibutramine in obese female subjects with type 2 diabetes and poor blood glucose control.

Journal: Diabetes care 20011101

Title: Current methods used for defining, measuring, and treating obesity.

Journal: Seminars in urologic oncology 20011101

Title: Long-term medication use and weight loss maintenance: an observational study.

Journal: Obesity research 20011001

Title: Long-term weight loss with sibutramine: a randomized controlled trial.

Journal: JAMA 20010919

Title: Effects of sibutramine on body weight and serum lipids: a double-blind, randomized, placebo-controlled study in 322 overweight and obese patients with dyslipidemia.

Journal: American heart journal 20010901

Title: Effect of moderate weight loss on health-related quality of life: an analysis of combined data from 4 randomized trials of sibutramine vs placebo.

Journal: The American journal of managed care 20010901

Title: Weight loss and health-related quality of life.

Journal: The American journal of managed care 20010901

Title: [Pharma-clinics. Medication of the month. Sibutramine (Reductil)].

Journal: Revue medicale de Liege 20010901

Title: Obesity: a new paradigm in endocrinology.

Journal: Eating and weight disorders : EWD 20010901

Title: The advances on the knowledge base of obesity and future therapeutic directions.

Journal: Eating and weight disorders : EWD 20010901

Title: [A randomized, double-blind, placebo-controlled, multicenter study on sibutramine in over-weighted and obese subjects].

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20010901

Title: Clinical evaluation of sibutramine in obese type 2 diabetic patients refractory to dietary management.

Journal: The Journal of the Association of Physicians of India 20010901

Title: Synergy of sibutramine and low-dose leptin in treatment of diet-induced obesity in rats.

Journal: Metabolism: clinical and experimental 20010801

Title: Obesity treatment with a progressive clinical tri-therapy combining sibutramine and a supervised diet--exercise intervention.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010801

Title: Insulin-leptin-visceral fat relation during weight loss.

Journal: Pancreas 20010801

Title: Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety.

Journal: Archives of internal medicine 20010801

Title: Relationship between insulin resistance, weight loss, and coronary heart disease risk in healthy, obese women.

Journal: Metabolism: clinical and experimental 20010701

Title: Metabolic changes following sibutramine-assisted weight loss in obese individuals: role of plasma free fatty acids in the insulin resistance of obesity.

Journal: Metabolism: clinical and experimental 20010701

Title: Drug treatment for obesity. We need more studies in men at higher risk of coronary events.

Journal: BMJ (Clinical research ed.) 20010609

Title: Randomized placebo-controlled trial of long-term treatment with sibutramine in mild to moderate obesity.

Journal: The Journal of family practice 20010601

Title: Treating obesity in the family practice setting.

Journal: Postgraduate medicine 20010601

Title: Achieving weight-loss maintenance.

Journal: Postgraduate medicine 20010601

Title: Exploring synergies in the treatment of obesity.

Journal: Postgraduate medicine 20010601

Title: Emerging strategies for weight management. Summary.

Journal: Postgraduate medicine 20010601

Title: [The effect of sibutramine for the maintenance of weight loss. A randomized controlled clinical trial].

Journal: Ugeskrift for laeger 20010521

Title: Second phase of a double-blind study clinical trial on Sibutramine for the treatment of patients suffering essential obesity: 6 months after treatment cross-over.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010501

Title: Current pharmacological approaches to the treatment of obesity.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010501

Title: Drug therapy for management of obesity.

Journal: Lancet (London, England) 20010421

Title: [Weight reduction. Doubly effective with drug support].

Journal: MMW Fortschritte der Medizin 20010412

Title: [Observational study. Sibutramine in general practice].

Journal: MMW Fortschritte der Medizin 20010412

Title: [Sibutramine--antidepressive agent tested against obesity].

Journal: Lakartidningen 20010411

Title: Sibutramine reduces feeding, body fat and improves insulin resistance in dietary-obese male Wistar rats independently of hypothalamic neuropeptide Y.

Journal: British journal of pharmacology 20010401

Title: Sibutramine metabolites increase glucose transport by cultured rat muscle cells.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010401

Title: Predictors of weight loss and maintenance during 2 years of treatment by sibutramine in obesity. Results from the European multi-centre STORM trial. Sibutramine Trial of Obesity Reduction and Maintenance.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010401

Title: Influence of sibutramine on energy expenditure in African American women.

Journal: Obesity research 20010401

Title: Toward optimal health: the experts discuss weight control drugs. Interview by Jodi Godfrey Meisler.

Journal: Journal of women's health & gender-based medicine 20010301

Title: Diet drug helps keep weight off.

Journal: Health news (Waltham, Mass.) 20010201

Title: Benefits of lifestyle modification in the pharmacologic treatment of obesity: a randomized trial.

Journal: Archives of internal medicine 20010122

Title: Serotonin syndrome: potential consequences of Meridia combined with Demerol or fentanyl.

Journal: Plastic and reconstructive surgery 20010101

Title: [Clinical study of the month. After the storm over central anorectic agents, the 'STORM' study of sibutramine].

Journal: Revue medicale de Liege 20010101

Title: Treating obesity: a new target for prevention of coronary heart disease.

Journal: Progress in cardiovascular nursing 20010101

Title: Epidemiology, morbidity, and treatment of overweight and obesity.

Journal: The Journal of clinical psychiatry 20010101

Title: Weight loss can be as simple as 10, 20, 30--Knoll launches blueprint for the use of sibutramine in weight management.

Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20010101

Title: An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action.

Journal: Obesity reviews : an official journal of the International Association for the Study of Obesity 20001001

Title: [Obesity: principles of drug therapy].

Journal: Therapeutische Umschau. Revue therapeutique 20000801

Title: Sibutramine: a serotonin-norepinephrine reuptake-inhibitor for the treatment of obesity.

Journal: The Annals of pharmacotherapy 19990901

Title: Sibutramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 19980801

Title: Sibutramine: a review of the pharmacology of a novel anti-obesity agent.

Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 19970301

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Tags:84485-00-7 Molecular Formula|84485-00-7 MDL|84485-00-7 SMILES|84485-00-7 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrochloride