Home Pyridines 845861-39-4
845861-39-4,MFCD03453293
Catalog No.:AA01CC4X

845861-39-4 | 1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-,monohydrochloride

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1mg
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5mg
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$123.00   $86.00
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10mg
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$218.00   $152.00
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25mg
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50mg
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01CC4X
Chemical Name:
1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-,monohydrochloride
CAS Number:
845861-39-4
Molecular Formula:
C15H20ClN3O
Molecular Weight:
293.7918
MDL Number:
MFCD03453293
SMILES:
CCCOc1ccc2c(n1)c(c[nH]2)C1=CCNCC1.Cl
Properties
Computed Properties
 
Complexity:
331  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  

Literature

Title: Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.

Journal: Neurobiology of disease 20120901

Title: The effect of serotonin 5HT1B receptor ligands on amphetamine self-administration in rats.

Journal: European journal of pharmacology 20120227

Title: Serotonin 1B autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior.

Journal: Biological psychiatry 20110415

Title: Activation of serotonin 5-HT(1B) receptor in the dorsal raphe nucleus affects REM sleep in the rat.

Journal: Behavioural brain research 20100105

Title: Neonatal DSP-4 treatment impairs 5-HT(1B) receptor reactivity in adult rats. Behavioral and biochemical studies.

Journal: Pharmacological reports : PR 20100101

Title: Serotonin 1B receptor stimulation reduces D1 receptor agonist-induced dyskinesia.

Journal: Neuroreport 20090923

Title: Effects of systemic 5-HT(1B) receptor compounds on ventral tegmental area intracranial self-stimulation thresholds in rats.

Journal: European journal of pharmacology 20090214

Title: Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia.

Journal: Brain : a journal of neurology 20081201

Title: MDMA treatment 6 months earlier attenuates the effects of CP-94,253, a 5-HT1B receptor agonist, on motor control but not sleep inhibition.

Journal: Brain research 20080922

Title: 5-HT(1B) receptor inhibition of alcohol-heightened aggression in mice: comparison to drinking and running.

Journal: Psychopharmacology 20080301

Title: 5-HT 1B receptor-mediated serotoninergic modulation of methylphenidate-induced locomotor activation in rats.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080201

Title: Effects of serotonin (5-HT)(1B) receptor ligands on cocaine-seeking behavior in rats.

Journal: Pharmacological reports : PR 20080101

Title: Anti-aggressive effects of agonists at 5-HT1B receptors in the dorsal raphe nucleus of mice.

Journal: Psychopharmacology 20070801

Title: Effect of 5-HT1B receptor agonists injected into the prefrontal cortex on maternal aggression in rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070601

Title: Effects of serotonin 5-HT1B receptor ligands on the cocaine- and food-maintained self-administration in rats.

Journal: European journal of pharmacology 20070322

Title: Serotonin reciprocally regulates melanocortin neurons to modulate food intake.

Journal: Neuron 20060720

Title: Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.

Journal: European journal of pharmacology 20060710

Title: 5-HT(1B) receptors, ventral orbitofrontal cortex, and aggressive behavior in mice.

Journal: Psychopharmacology 20060501

Title: Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse.

Journal: Psychopharmacology 20060301

Title: Acute and long-term effects of a single dose of MDMA on aggression in Dark Agouti rats.

Journal: The international journal of neuropsychopharmacology 20060201

Title: Involvement of 5-HT1B receptors within the ventral tegmental area in ethanol-induced increases in mesolimbic dopaminergic transmission.

Journal: Brain research 20051026

Title: Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action.

Journal: European journal of pharmacology 20050523

Title: The anxiolytic-like effect of 5-HT1B receptor ligands in rats: a possible mechanism of action.

Journal: The Journal of pharmacy and pharmacology 20050201

Title: Effects of a selective 5-HT1B receptor agonist and antagonists in animal models of anxiety and depression.

Journal: Behavioural pharmacology 20041201

Title: Role of alcohol consumption in escalation to violence.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Tonic regulation of satiety by 5-HT receptors in the mouse: converging evidence from behavioural and c-fos immunoreactivity studies?

Journal: The European journal of neuroscience 20040601

Title: 5-HT1B receptors modulate components of satiety in the rat: behavioural and pharmacological analyses of the selective serotonin1B agonist CP-94,253.

Journal: Psychopharmacology 20021001

Title: Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems.

Journal: Psychopharmacology 20021001

Title: Stimulation of serotonin1B receptors induces conditioned place aversion and facilitates cocaine place conditioning in rats.

Journal: Psychopharmacology 20020901

Title: Anxiogenic-like effect of serotonin(1B) receptor stimulation in the rat elevated plus-maze.

Journal: Pharmacology, biochemistry, and behavior 20020401

Title: Role of 5-hT2C receptors in the hypophagic effect of m-CPP, ORG 37684 and CP-94,253 in the rat.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020401

Title: The role of 5-HT1B receptors in the regulation of serotonin cell firing and release in the rat brain.

Journal: Journal of neurochemistry 20011001

Title: Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse.

Journal: The Journal of pharmacology and experimental therapeutics 20010901

Title: Serotonergic effects and extracellular brain levels of eletriptan, zolmitriptan and sumatriptan in rat brain.

Journal: European journal of pharmacology 20010817

Title: Role of 5-HT(1B) receptors in the sensitization to amphetamine in mice.

Journal: European journal of pharmacology 20010622

Title: Effect of serotonin (5-HT)1B receptor ligands on cocaine sensitization in rats.

Journal: Behavioural pharmacology 20010401

Title: Serotonin1B receptor stimulation enhances cocaine reinforcement.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19981201

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Tags:845861-39-4 Molecular Formula|845861-39-4 MDL|845861-39-4 SMILES|845861-39-4 1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-,monohydrochloride