Catalog No.:AA00G3AF

849214-04-6 | c-GpAp

Name: Name:c-GpAp
Brand: AABLOCKS
SKU: AA00G3AF
Availability: InStock
Rating: 90 (10 reviews)

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Purity

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1mg

98%

in stock

$369.00 $259.00

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA00G3AF

Chemical Name:

c-GpAp

CAS Number:

849214-04-6

Molecular Formula:

C20H24N10O13P2

Molecular Weight:

674.4113

MDL Number:

MFCD28411367

SMILES:

Nc1nc(=O)c2c([nH]1)n(cn2)[C@@H]1O[C@H]2[C@H]([C@H]1OP(=O)(O)OC[C@@H]1[C@@H](OP(=O)(OC2)O)[C@H]([C@@H](O1)n1cnc2c1ncnc2N)O)O

Properties

Computed Properties

Complexity:

1300

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

-5.9

Literature

Title: Wu J, et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.Science. 2013 Feb 15;339(6121):826-30.

Title: Skrnjug I, et al. Cyclic GMP-AMP displays mucosal adjuvant activity in mice. PLoS One. 2014 Oct 8;9(10):e110150.

Title: Liu Y, et al. Activated STING in a vascular and pulmonary syndrome. N Engl J Med. 2014 Aug 7;371(6):507-18.

Title: Ablasser A, et al. Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. Nature. 2013 Nov 28;503(7477):530-4.

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