Name: Name:N-Methyl 4-borono-2-fluorobenzamide
Brand: AABLOCKS
SKU: AA0036DV
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0036DV

Chemical Name: N-Methyl 4-borono-2-fluorobenzamide

CAS Number: 849833-86-9

Molecular Formula: C8H9BFNO3

Molecular Weight: 196.9714

MDL Number: MFCD08436026

SMILES: CNC(=O)c1ccc(cc1F)B(O)O

Properties

Form: Solid

MP: 173-175

Storage: Keep in dry area;2-8℃;

Complexity: 215

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 14

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Downstream Synthesis Route

1002308-57-7

849833-86-9

2-fluoro-4-(3-((7-methoxyquinolin-4-yloxy)methyl)-1,2,4triazolo4,3-bpyridazin-6-yl)-N-methylbenzamide

[1]Albrecht,BrianK.;Harmange,Jean-Christophe;Bauer,David;Berry,Loren;Bode,Christiane;Boezio,AlessandroA.;Chen,April;Choquette,Deborah;Dussault,Isabelle;Fridrich,Cary;Hirai,Satoko;Hoffman,Doug;Larrow,JayF.;Kaplan-Lefko,Paula;Lin,Jasmine;Lohman,Julia;Long,AlexanderM.;Moriguchi,Jodi;O'Connor,Anne;Potashman,MicheleH.;Reese,Monica;Rex,Karen;Siegmund,Aaron;Shah,Kavita;Shimanovich,Roman;Springer,StephanieK.;Teffera,Yohannes;Yang,Yajing;Zhang,Yihong;Bellon,StevenF.[JournalofMedicinalChemistry,2008,vol.51,#10,p.2879-2882]

849833-86-9

1174728-43-8

1174721-35-7

[1]CurrentPatentAssignee:LIGANDPHARMACEUTICALSINC;TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2009/97567,2009,A1Locationinpatent:Page/Pagecolumn77

849833-86-9

1363401-52-8

1363401-51-7

[1]Guo,Chuangxing;Pairish,Mason;Linton,Angelica;Kephart,Susan;Ornelas,Martha;Nagata,Asako;Burke,Benjamin;Dong,Liming;Engebretsen,Jon;Fanjul,AndreaN.[BioorganicandMedicinalChemistryLetters,2012,vol.22,#7,p.2572-2578]

849833-86-9

1363401-54-0

1363401-55-1

[1]Guo,Chuangxing;Pairish,Mason;Linton,Angelica;Kephart,Susan;Ornelas,Martha;Nagata,Asako;Burke,Benjamin;Dong,Liming;Engebretsen,Jon;Fanjul,AndreaN.[BioorganicandMedicinalChemistryLetters,2012,vol.22,#7,p.2572-2578]

849833-86-9

(±)trans-1-(4-cyano-3-(trifluoromethyl)phenyl)-3-methyl-2-oxo-2,3,3a,6,7,7a-hexahydro-1H-benzodimidazol-5-yltrifluoromethanesulfonate

(±)-trans-4-(1-(4-cyano-3-(trifluoromethyl)phenyl)-3-methyl-2-oxo-2,3,3a,6,7,7a-hexahydro-1H-benzodimidazol-5-yl)-2-fluoro-N-methylbenzamide

[1]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-WO2013/84138,2013,A1Locationinpatent:Page/Pagecolumn99

[2]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-US2014/329858,2014,A1Locationinpatent:Paragraph0540;0541

849833-86-9 | N-Methyl 4-borono-2-fluorobenzamide