Home Other Building Blocks 852146-73-7
852146-73-7,MFCD08705324
Catalog No.:AA00GLU7

852146-73-7 | KR-32568

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$99.00   $69.00
- +
5mg
≥98%
in stock  
$222.00   $155.00
- +
  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GLU7
Chemical Name:
KR-32568
CAS Number:
852146-73-7
Molecular Formula:
C13H12FN3O2
Molecular Weight:
261.2517
MDL Number:
MFCD08705324
SMILES:
NC(=N)NC(=O)c1ccc(o1)c1cc(F)ccc1C
Properties
Computed Properties
 
Complexity:
371  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
2.4  

Literature

Title: Hydrogen sulfide regulates Na+/H+ exchanger activity via stimulation of phosphoinositide 3-kinase/Akt and protein kinase G pathways.

Journal: The Journal of pharmacology and experimental therapeutics 20111101

Title: Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury.

Journal: Pharmacology 20051201

Title: (5-Arylfuran-2-ylcarbonyl)guanidines as cardioprotectives through the inhibition of Na+/H+ exchanger isoform-1.

Journal: Journal of medicinal chemistry 20050421

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