Home Other Building Blocks 852391-15-2
852391-15-2,MFCD19443135
Catalog No.:AA00G3MK

852391-15-2 | Necrostatin 2 racemate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$58.00   $40.00
- +
5mg
≥98%
in stock  
$169.00   $118.00
- +
100mg
98%
in stock  
$193.00   $135.00
- +
250mg
98%
in stock  
$403.00   $282.00
- +
1g
98%
in stock  
$1,206.00   $844.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3MK
Chemical Name:
Necrostatin 2 racemate
CAS Number:
852391-15-2
Molecular Formula:
C13H12ClN3O2
Molecular Weight:
277.7063
MDL Number:
MFCD19443135
SMILES:
CN1C(=O)C(NC1=O)Cc1c[nH]c2c1cccc2Cl
NSC Number:
745841
Properties
Computed Properties
 
Complexity:
403  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.9  

Literature

Title: Necrostatin-1 blocks both RIPK1 and IDO: consequences for the study of cell death in experimental disease models.

Journal: Cell death and differentiation 20130201

Title: Structure-activity relationship study of novel necroptosis inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20051115

Title: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.

Journal: Nature chemical biology 20050701

Title: Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19980915

Title: Takahashi N, et al. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis. 2012 Nov 29;3:e437.

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Tags:852391-15-2 Molecular Formula|852391-15-2 MDL|852391-15-2 SMILES|852391-15-2 Necrostatin 2 racemate