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853910-02-8,MFCD16618394
Catalog No.:AA004OUD

853910-02-8 | NVP-BAG956(BAG 956)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$53.00   $37.00
- +
5mg
≥98%
in stock  
$216.00   $151.00
- +
10mg
≥98%
in stock  
$330.00   $231.00
- +
25mg
99%
in stock  
$696.00   $487.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA004OUD
Chemical Name:
NVP-BAG956(BAG 956)
CAS Number:
853910-02-8
Molecular Formula:
C28H21N5
Molecular Weight:
427.4998
MDL Number:
MFCD16618394
SMILES:
N#CC(c1ccc(cc1)n1c(C)nc2c1c1cc(C#Cc3cccnc3)ccc1nc2)(C)C
Properties
Properties
 
Form:
Solid  
MP:
>224ºC (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
806  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
5.3  

Literature

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters 20130801

Title: Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levels.

Journal: Oncotarget 20120801

Title: Potentiation of antileukemic therapies by the dual PI3K/PDK-1 inhibitor, BAG956: effects on BCR-ABL- and mutant FLT3-expressing cells.

Journal: Blood 20080401

Title: Marone R, et al. Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors. Mol Cancer Res. 2009 Apr;7(4):601-13.

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SDS
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Tags:853910-02-8 Molecular Formula|853910-02-8 MDL|853910-02-8 SMILES|853910-02-8 NVP-BAG956(BAG 956)