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85511-68-8,MFCD18642601
Catalog No.:AA01KKZF

85511-68-8 | 7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$13.00   $9.00
- +
5mg
98%
in stock  
$29.00   $21.00
- +
10mg
98%
in stock  
$44.00   $31.00
- +
25mg
98%
in stock  
$74.00   $52.00
- +
50mg
98%
in stock  
$125.00   $88.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01KKZF
Chemical Name:
7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione
CAS Number:
85511-68-8
Molecular Formula:
C16H9ClF3NO2
Molecular Weight:
339.6964
MDL Number:
MFCD18642601
SMILES:
O=C1c2cccc(c2N(C1=O)Cc1ccc(cc1)C(F)(F)F)Cl
Properties

Downstream Synthesis Route

[1]Bridges,ThomasM.;Marlo,JoyE.;Niswender,ColleenM.;Jones,CarrieK.;Jadhav,SatyawanB.;Gentry,PatrickR.;Plumley,HyekyungC.;Weaver,C.David;Conn,P.Jeffrey;Lindsley,CraigW.[JournalofMedicinalChemistry,2009,vol.52,#11,p.3445-3448]

Literature

Title: Thomas M Bridges, et al. Chemical lead optimization of a pan G(q) mAChR M(1), M(3), M(5) positive allosteric modulator (PAM) lead. Part I: Development of the first highly selective M(5) PAM. Bioorg Med Chem Lett. 2010 Jan 15;20(2):558-62.

Title: Thomas M Bridges, et al. Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins. J Med Chem. 2009 Jun 11;52(11):3445-8.

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Tags:85511-68-8 Molecular Formula|85511-68-8 MDL|85511-68-8 SMILES|85511-68-8 7-Chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione