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858102-79-1,MFCD22572774
Catalog No.:AA01CCD0

858102-79-1 | Rolapitant hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$352.00   $247.00
- +
5mg
95%
1 week  
$791.00   $554.00
- +
10mg
95%
1 week  
$1,101.00   $771.00
- +
25mg
95%
1 week  
$1,623.00   $1,136.00
- +
50mg
95%
1 week  
$2,172.00   $1,520.00
- +
100mg
95%
1 week  
$2,915.00   $2,040.00
- +
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  • Technical Information
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Technical Information
Catalog Number:
AA01CCD0
Chemical Name:
Rolapitant hydrochloride
CAS Number:
858102-79-1
MDL Number:
MFCD22572774
Properties
Computed Properties
 
Complexity:
731  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  

Literature

Title: Duffy RA, et al. Rolapitant (SCH 619734): a potent, selective and orally active neurokininNK1 receptor antagonist with centrally-mediated antiemetic effects inferrets. Pharmacol Biochem Behav. 2012 Jul;102(1):95-100.

Title: Rapoport B, et al. Study of rolapitant, a novel, long-acting, NK-1 receptor antagonist, for the prevention of chemotherapy-induced nausea and vomiting (CINV) due to highly emetogenic chemotherapy (HEC). Support Care Cancer. 2015 Nov;23(11):3281-8.

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SDS
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