[1]Asaki,Tetsuo;Sugiyama,Yukiteru;Hamamoto,Taisuke;Higashioka,Masaya;Umehara,Masato;Naito,Haruna;Niwa,Tomoko[BioorganicandMedicinalChemistryLetters,2006,vol.16,#5,p.1421-1425]
[2]CurrentPatentAssignee:NIPPONSHINYAKUCOLTD-EP1702917,2006,A1Locationinpatent:Page/Pagecolumn66-67
[1]BioorganicandMedicinalChemistryLetters,2006,vol.16,p.1421-1425
[1]Asaki,Tetsuo;Sugiyama,Yukiteru;Hamamoto,Taisuke;Higashioka,Masaya;Umehara,Masato;Naito,Haruna;Niwa,Tomoko[BioorganicandMedicinalChemistryLetters,2006,vol.16,#5,p.1421-1425]
[1]Asaki,Tetsuo;Sugiyama,Yukiteru;Hamamoto,Taisuke;Higashioka,Masaya;Umehara,Masato;Naito,Haruna;Niwa,Tomoko[BioorganicandMedicinalChemistryLetters,2006,vol.16,#5,p.1421-1425]
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Title: A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib.
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Title: KIT polymorphisms and mutations determine responses of neoplastic mast cells to bafetinib (INNO-406).
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Title: Phase 1 study of INNO-406, a dual Abl/Lyn kinase inhibitor, in Philadelphia chromosome-positive leukemias after imatinib resistance or intolerance.
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Title: A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells.
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Title: Development of novel tyrosine kinase inhibitors for treatment of imatinib-resistant CML patients.
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Title: Imatinib and its successors--how modern chemistry has changed drug development.
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Title: The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias.
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Title: Comparison of imatinib, dasatinib, nilotinib and INNO-406 in imatinib-resistant cell lines.
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Title: Overcoming imatinib resistance using Src inhibitor CGP76030, Abl inhibitor nilotinib and Abl/Lyn inhibitor INNO-406 in newly established K562 variants with BCR-ABL gene amplification.
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Title: Management of patients with resistant or refractory chronic myelogenous leukemia.
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Title: Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia.
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Title: Structural factors contributing to the Abl/Lyn dual inhibitory activity of 3-substituted benzamide derivatives.
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Title: INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity.
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Title: NS-187 (INNO-406), a Bcr-Abl/Lyn dual tyrosine kinase inhibitor.
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