Home Fluorides 864756-35-4
864756-35-4,MFCD26792560
Catalog No.:AA01ENLR

864756-35-4 | 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone

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Purity
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5mg
≥97%(HPLC)
in stock  
$1,091.00   $764.00
- +
10mg
≥97%(HPLC)
in stock  
$1,920.00   $1,344.00
- +
25mg
≥97%(HPLC)
in stock  
$4,245.00   $2,972.00
- +
50mg
≥97%(HPLC)
in stock  
$7,595.00   $5,317.00
- +
100mg
≥97%(HPLC)
in stock  
$13,625.00   $9,538.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01ENLR
Chemical Name:
4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone
CAS Number:
864756-35-4
Molecular Formula:
C24H25FN2O3
Molecular Weight:
408.4653
MDL Number:
MFCD26792560
SMILES:
Fc1ccc(cc1)COc1ccn(c(=O)c1)c1ccc(cc1)OCCN1CCCC1
Properties
Computed Properties
 
Complexity:
616  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
8  
XLogP3:
3.7  

Literature

Title: Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonists.

Journal: Bioorganic & medicinal chemistry 20110115

Title: Discovery of novel phenethylpyridone derivatives as potent melanin-concentrating hormone 1 receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20090901

Title: Ito M, et al. Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice. Eur J Pharmacol. 2009 Dec 10;624(1-3):77-83.

Title: Haga Y, et al. Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonists. Bioorg Med Chem. 2011 Jan 15;19(2):883-93.

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Tags:864756-35-4 Molecular Formula|864756-35-4 MDL|864756-35-4 SMILES|864756-35-4 4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone