Home Other Building Blocks 864953-39-9
864953-39-9,MFCD23098797
Catalog No.:AA00GTZ6

864953-39-9 | BMS 663068 (Tris)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$126.00   $88.00
- +
2mg
95%
1 week  
$157.00   $110.00
- +
5mg
95%
1 week  
$226.00   $158.00
- +
100mg
98+%
1 week  
$263.00   $184.00
- +
250mg
98+%
1 week  
$391.00   $274.00
- +
1g
98+%
1 week  
$988.00   $692.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00GTZ6
Chemical Name:
BMS 663068 (Tris)
CAS Number:
864953-39-9
Molecular Formula:
C29H37N8O11P
Molecular Weight:
704.6248
MDL Number:
MFCD23098797
SMILES:
OCC(CO)(CO)N.COc1cnc(c2c1c(cn2COP(=O)(O)O)C(=O)C(=O)N1CCN(CC1)C(=O)c1ccccc1)n1cnc(n1)C
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-US2005/209246,2005,A1Locationinpatent:Page/Pagecolumn46-48;54

[1]CurrentPatentAssignee:GLAXOSMITHKLINEPLC-US2007/155702,2007,A1Locationinpatent:Page/Pagecolumn12

701213-36-7   
1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium(3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo2,3-cpyridin-1-yl)methylhydrogenphosphate 

[1]Fox,RichardJ.;Tripp,JonathanC.;Schultz,MitchellJ.;Payack,JosephF.;Fanfair,DayneD.;Mudryk,BoguslawM.;Murugesan,Saravanababu;Chen,Chung-PinH.;LaCruz,ThomasE.;Ivy,SabrinaE.;Broxer,Sévrine;Cullen,Ryan;Erdemir,Deniz;Geng,Peng;Xu,Zhongmin;Fritz,Alan;Doubleday,WendelW.;Conlon,DavidA.[OrganicProcessResearchandDevelopment,2017,vol.21,#8,p.1095-1109]

[2]Fox,RichardJ.;Tripp,JonathanC.;Schultz,MitchellJ.;Payack,JosephF.;Fanfair,DayneD.;Mudryk,BoguslawM.;Murugesan,Saravanababu;Chen,Chung-PinH.;LaCruz,ThomasE.;Ivy,SabrinaE.;Broxer,Sévrine;Cullen,Ryan;Erdemir,Deniz;Geng,Peng;Xu,Zhongmin;Fritz,Alan;Doubleday,WendelW.;Conlon,DavidA.[OrganicProcessResearchandDevelopment,2017,vol.21,#8,p.1095-1109]

[3]Wang,Tao;Ueda,Yasu;Zhang,Zhongxing;Yin,Zhiwei;Matiskella,John;Pearce,BradleyC.;Yang,Zheng;Zheng,Ming;Parker,DawnD.;Yamanaka,GregoryA.;Gong,Yi-Fei;Ho,Hsu-Tso;Colonno,RichardJ.;Langley,DavidR.;Lin,Pin-Fang;Meanwell,NicholasA.;Kadow,JohnF.[JournalofMedicinalChemistry,2018,vol.61,#14,p.6308-6327]

Literature

Title: Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56(7):3498-507.

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SDS
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