Name: Name:tert-Butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
Brand: AABLOCKS
SKU: AA00GU42
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00GU42

Chemical Name: tert-Butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate

CAS Number: 866084-31-3

Molecular Formula: C32H43N7O4

Molecular Weight: 589.7283

MDL Number: MFCD28978558

SMILES: CCCOC(=C)c1c(C)c2cnc(nc2n(c1=O)C1CCCC1)Nc1ccc(cn1)N1CCN(CC1)C(=O)OC(C)(C)C

Properties

Downstream Synthesis Route

tert‑butyl4‑(6‑((6‑(1‑butoxyvinyl)‑8‑cyclopentyl‑5‑methyl‑7‑oxo‑7,8‑dihydropyrido2,3‑dpyrimidin‑2‑yl)amino)pyridin‑3‑yl)piperazine‑1‑carboxylate

107-36-8

PD0332991isethionate

[1]Patent:WO2005/5426,2005,A1.Locationinpatent:Page/Pagecolumn25;26

[2]Patent:US2005/222163,2005,A1.Locationinpatent:Page/Pagecolumn28

[3]Patent:WO2008/32157,2008,A2.Locationinpatent:Page/Pagecolumn28

1016636-76-2

866084-31-3

[1]CurrentPatentAssignee:PFIZERINC-WO2014/128588,2014,A1

[2]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2016/30439,2016,A1

[3]CurrentPatentAssignee:TETRANOVBIOPHARM-CN104447739,2016,B

[4]CurrentPatentAssignee:NANJINGNMGADDS-CN105541832,2016,A

[5]CurrentPatentAssignee:HEFEIYUANZHIPHARMACEUTICALRD-CN106220627,2016,A

[6]CurrentPatentAssignee:KINGLAWRENCE;CIPLALTD-WO2018/73574,2018,A1

[7]CurrentPatentAssignee:CHONGQINGSANSHENG-CN109336886,2019,A

[8]Su,Shang;Yang,Zimo;Gao,Hongying;Yang,Haiyan;Zhu,Songbiao;An,Zixuan;Wang,Juanjuan;Li,Qing;Chandarlapaty,Sarat;Deng,Haiteng;Wu,Wei;Rao,Yu[JournalofMedicinalChemistry,2019,vol.62,#16,p.7575-7582]

[9]CurrentPatentAssignee:JIANGXIGUOYAOPHARMACEUTICAL-CN112552297,2021,A

tert‑butyl4‑(6‑((6‑(1‑butoxyvinyl)‑8‑cyclopentyl‑5‑methyl‑7‑oxo‑7,8‑dihydropyrido2,3‑dpyrimidin‑2‑yl)amino)pyridin‑3‑yl)piperazine‑1‑carboxylate

571190-30-2

[1]Patent:WO2014/128588,2014,A1.Locationinpatent:Page/Pagecolumn39;40;41

[2]Patent:CN109336886,2019,A.Locationinpatent:Paragraph0039;0042;0043;0047

[3]Patent:CN105541832,2016,A.Locationinpatent:Paragraph0047;0048;0049;0066;0067;0068

[4]Patent:WO2016/30439,2016,A1.Locationinpatent:Page/Pagecolumn36

[5]ChemicalPapers,2019,vol.73,p.3043-3051

[6]Patent:CN104447739,2016,B

[7]Patent:CN106220627,2016,A

[8]Patent:CN106220627,2016,A

[9]Patent:CN106397431,2017,A