Title: Metformin alleviated endotoxemia-induced acute lung injury via restoring AMPK-dependent suppression of mTOR.
Journal: Chemico-biological interactions20180801
Title: Vosaroxin induces mitochondrial dysfunction and apoptosis in cervical cancer HeLa cells: Involvement of AMPK/Sirt3/HIF-1 pathway.
Journal: Chemico-biological interactions20180625
Title: Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase.
Journal: Chemico-biological interactions20180601
Title: Traditional herbal medicine-derived sulforaphene promotes mitophagic cell death in lymphoma cells through CRM1-mediated p62/SQSTM1 accumulation and AMPK activation.
Journal: Chemico-biological interactions20180201
Title: Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation.
Journal: Chemico-biological interactions20171225
Title: 4-Nonylphenol induces autophagy and attenuates mTOR-p70S6K/4EBP1 signaling by modulating AMPK activation in Sertoli cells.
Journal: Toxicology letters20170205
Title: Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats.
Journal: Archives of toxicology20170101
Title: Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox(ukn) and STOP-Tox(ukk) tests.
Journal: Archives of toxicology20170101
Title: Vagal nerve stimulation improves mitochondrial dynamics via an M(3) receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia.
Journal: Journal of cellular and molecular medicine20170101
Title: Effect of A-769662, a direct AMPK activator, on Tlr-4 expression and activity in mice heart tissue.
Journal: Iranian journal of basic medical sciences20161201
Title: From the Cover: Autophagy Induction Contributes to Cadmium Toxicity in Mesenchymal Stem Cells via AMPK/FOXO3a/BECN1 Signaling.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20161101
Title: Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes.
Journal: Toxicology20160831
Title: Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs.
Journal: Molecular oncology20160601
Title: Quercetin oppositely regulates insulin-mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation.
Journal: Molecular nutrition & food research20160301
Title: Gastrodin Ameliorates Oxidative Stress and Proinflammatory Response in Nonalcoholic Fatty Liver Disease through the AMPK/Nrf2 Pathway.
Journal: Phytotherapy research : PTR20160301
Title: Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation.
Journal: Annals of the rheumatic diseases20160201
Title: Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK.
Journal: Journal of neuroinflammation20160101
Title: Suppressed translation and ULK1 degradation as potential mechanisms of autophagy limitation under prolonged starvation.
Journal: Autophagy20160101
Title: Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
Journal: Chemico-biological interactions20151005
Title: Resveratrol attenuates high glucose-induced oxidative stress and cardiomyocyte apoptosis through AMPK.
Journal: Molecular and cellular endocrinology20150905
Title: Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway.
Journal: Molecular nutrition & food research20150801
Title: Resveratrol induces brown-like adipocyte formation in white fat through activation of AMP-activated protein kinase (AMPK) α1.
Journal: International journal of obesity (2005)20150601
Title: A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression.
Journal: Experimental hematology20150501
Title: Regorafenib impairs mitochondrial functions, activates AMP-activated protein kinase, induces autophagy, and causes rat hepatocyte necrosis.
Journal: Toxicology20150102
Title: Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences.
Journal: Cell & bioscience20150101
Title: Resveratrol regulates mitochondrial reactive oxygen species homeostasis through Sirt3 signaling pathway in human vascular endothelial cells.
Journal: Cell death & disease20141201
Title: Resveratrol reduces morphine tolerance by inhibiting microglial activation via AMPK signalling.
Journal: European journal of pain (London, England)20141101
Title: Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1.
Journal: Pharmacological research20141101
Title: AMP-activated protein kinase mediates the antioxidant effects of resveratrol through regulation of the transcription factor FoxO1.
Journal: The FEBS journal20141001
Title: Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension20140901
Title: Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): a highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent.
Journal: Journal of medicinal chemistry20140522
Title: Quercetin differently regulates insulin-mediated glucose transporter 4 translocation under basal and inflammatory conditions in adipocytes.
Journal: Molecular nutrition & food research20140501
Title: Metformin induces PGC-1α expression and selectively affects hepatic PGC-1α functions.
Journal: British journal of pharmacology20140501
Title: Inhibitory effects of resveratrol on foam cell formation are mediated through monocyte chemotactic protein-1 and lipid metabolism-related proteins.
Journal: International journal of molecular medicine20140501
Title: Resveratrol down-regulates a glutamate-induced tissue plasminogen activator via Erk and AMPK/mTOR pathways in rat primary cortical neurons.
Journal: Food & function20140501
Title: The role of AMP-activated protein kinase in quercetin-induced apoptosis of HL-60 cells.
Journal: Acta biochimica et biophysica Sinica20140501
Title: Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20140301
Title: Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1.
Journal: Journal of lipid research20140301
Title: Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes.
Journal: Toxicology and applied pharmacology20140115
Title: A high-throughput screen for teratogens using human pluripotent stem cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology20140101
Title: Protective effect of resveratrol derivatives on high-fat diet induced fatty liver by activating AMP-activated protein kinase.
Journal: Archives of pharmacal research20140101
Title: Salidroside stimulates osteoblast differentiation through BMP signaling pathway.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20131201
Title: Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway.
Journal: Autophagy20131201
Title: Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells.
Journal: The Biochemical journal20130901
Title: S-allyl cysteine attenuates free fatty acid-induced lipogenesis in human HepG2 cells through activation of the AMP-activated protein kinase-dependent pathway.
Journal: The Journal of nutritional biochemistry20130801
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters20130801
Title: Autophagic cell death induced by resveratrol depends on the Ca(2+)/AMPK/mTOR pathway in A549 cells.
Journal: Biochemical pharmacology20130715
Title: Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe.
Journal: Bioorganic & medicinal chemistry letters20130601
Title: Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20130515
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal20130415
Title: Saponins, especially platycodin D, from Platycodon grandiflorum modulate hepatic lipogenesis in high-fat diet-fed rats and high glucose-exposed HepG2 cells.
Journal: Toxicology and applied pharmacology20130301
Title: p53 modulates the AMPK inhibitor compound C induced apoptosis in human skin cancer cells.
Journal: Toxicology and applied pharmacology20130215
Title: Resveratrol pre-treatment reduces early inflammatory responses induced by status epilepticus via mTOR signaling.
Journal: Brain research20130125
Title: Quercetin but not quercitrin ameliorates tumor necrosis factor-alpha-induced insulin resistance in C2C12 skeletal muscle cells.
Journal: Biological & pharmaceutical bulletin20130101
Title: ULK1 plays a critical role in AMPK-mediated myocardial autophagy and contractile dysfunction following acute alcohol challenge.
Journal: Current pharmaceutical design20130101
Title: BMP9 is a proliferative and survival factor for human hepatocellular carcinoma cells.
Journal: PloS one20130101
Title: Potent vasodilation effect of amurensin G is mediated through the phosphorylation of endothelial nitric oxide synthase.
Journal: Biochemical pharmacology20121201
Title: AMPK inhibitor compound C suppresses cell proliferation by induction of apoptosis and autophagy in human colorectal cancer cells.
Journal: Journal of surgical oncology20121101
Title: Acute exposure to resveratrol inhibits AMPK activity in human skeletal muscle cells.
Journal: Diabetologia20121101
Title: AMP-activated protein kinase upregulates glucose uptake in thyroid PCCL3 cells independent of thyrotropin.
Journal: Thyroid : official journal of the American Thyroid Association20121001
Title: Cerulein hyperstimulation decreases AMP-activated protein kinase levels at the site of maximal zymogen activation.
Journal: American journal of physiology. Gastrointestinal and liver physiology20120915
Title: The chemokine CCL5 regulates glucose uptake and AMP kinase signaling in activated T cells to facilitate chemotaxis.
Journal: The Journal of biological chemistry20120824
Title: AMP-activated protein kinase mediates erythropoietin-induced activation of endothelial nitric oxide synthase.
Journal: Journal of cellular physiology20120801
Title: Involvement of AMP-activated protein kinase in thrombin-stimulated interleukin 6 synthesis in osteoblasts.
Journal: Journal of molecular endocrinology20120801
Title: The trifunctional protein mediates thyroid hormone receptor-dependent stimulation of mitochondria metabolism.
Journal: Molecular endocrinology (Baltimore, Md.)20120701
Title: Effects of the AMP-activated protein kinase inhibitor compound C on the postconditioned rat heart.
Journal: The journal of physiological sciences : JPS20120701
Title: AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.
Journal: Circulation research20120427
Title: BMP signaling is responsible for serum-induced Id2 expression.
Journal: Biochemical and biophysical research communications20120406
Title: Human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by AMP-activated protein kinase.
Journal: Journal of cellular physiology20120401
Title: The herbal composition GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica reduces obesity via skeletal muscle AMPK and PPARα.
Journal: Pharmaceutical biology20120401
Title: Bone morphogenetic protein (BMP) signaling regulates mitotic checkpoint protein levels in human breast cancer cells.
Journal: Cellular signalling20120401
Title: Effect of metformin on the proliferation, migration, and MMP-2 and -9 expression of human umbilical vein endothelial cells.
Journal: Molecular medicine reports20120401
Title: Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation.
Journal: European journal of immunology20120301
Title: Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway.
Journal: The Prostate20120201
Title: Role of AMP-activated protein kinase in α-lipoic acid-induced vasodilatation in spontaneously hypertensive rats.
Journal: American journal of hypertension20120201
Title: Ginsenoside Rg2 induces orphan nuclear receptor SHP gene expression and inactivates GSK3β via AMP-activated protein kinase to inhibit hepatic glucose production in HepG2 cells.
Journal: Chemico-biological interactions20120105
Title: The adenosine derivative 2',3',5'-tri-O-acetyl-N6-(3-hydroxylaniline) adenosine activates AMPK and regulates lipid metabolism in vitro and in vivo.
Journal: Life sciences20120102
Title: AMP-activated protein kinase regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts: involvement of mitogen-activated protein kinases.
Journal: Life sciences20120102
Title: Prunus yedoensis Matsum. stimulates glucose uptake in L6 rat skeletal muscle cells by activating AMP-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways.
Journal: Natural product research20120101
Title: BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm.
Journal: Developmental biology20120101
Title: Mangiferin decreases plasma free fatty acids through promoting its catabolism in liver by activation of AMPK.
Journal: PloS one20120101
Title: Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cells.
Journal: PloS one20120101
Title: AMP-activated protein kinase plays an important evolutionary conserved role in the regulation of glucose metabolism in fish skeletal muscle cells.
Journal: PloS one20120101
Title: Chlorogenic acid stimulates glucose transport in skeletal muscle via AMPK activation: a contributor to the beneficial effects of coffee on diabetes.
Journal: PloS one20120101
Title: Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20120101
Title: Compound C prevents the unfolded protein response during glucose deprivation through a mechanism independent of AMPK and BMP signaling.
Journal: PloS one20120101
Title: Identification of an annonaceous acetogenin mimetic, AA005, as an AMPK activator and autophagy inducer in colon cancer cells.
Journal: PloS one20120101
Title: Metformin stimulates FGF21 expression in primary hepatocytes.
Journal: Experimental diabetes research20120101
Title: Glomerular endothelial PI3 kinase-α couples to VEGFR2, but is not required for eNOS activation.
Journal: American journal of physiology. Renal physiology20111201
Title: AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation.
Journal: American journal of physiology. Renal physiology20111201
Title: The specificities of small molecule inhibitors of the TGFß and BMP pathways.
Journal: Cellular signalling20111101
Title: Compound C independent of AMPK inhibits ICAM-1 and VCAM-1 expression in inflammatory stimulants-activated endothelial cells in vitro and in vivo.
Journal: Atherosclerosis20111101
Title: Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway.
Journal: Genes to cells : devoted to molecular & cellular mechanisms20111101
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology20111101
Title: Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes.
Journal: Molecular and cellular endocrinology20111015
Title: Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway.
Journal: European journal of pharmacology20111001
Title: Application of small organic molecules reveals cooperative TGFβ and BMP regulation of mesothelial cell behaviors.
Journal: ACS chemical biology20110916
Title: Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells.
Journal: Toxicology and applied pharmacology20110915
Title: Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice.
Journal: American journal of physiology. Heart and circulatory physiology20110901
Title: Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells.
Journal: Anatomy & cell biology20110901
Title: Compound C stimulates heme oxygenase-1 gene expression via the Nrf2-ARE pathway to preserve human endothelial cell survival.
Journal: Biochemical pharmacology20110815
Title: Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathways.
Journal: Chemical Society reviews20110814
Title: AICAR and Compound C regulate food intake independently of AMP-activated protein kinase in lines of chickens selected for high or low body weight.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology20110801
Title: Ischemia-induced stimulation of Na-K-Cl cotransport in cerebral microvascular endothelial cells involves AMP kinase.
Journal: American journal of physiology. Cell physiology20110801
Title: Compound C inhibits vascular smooth muscle cell proliferation and migration in an AMP-activated protein kinase-independent fashion.
Journal: The Journal of pharmacology and experimental therapeutics20110801
Title: Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease.
Journal: Neuro-Signals20110801
Title: Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells.
Journal: American journal of respiratory cell and molecular biology20110701
Title: Simulated microgravity promoted differentiation of bipotential murine oval liver stem cells by modulating BMP4/Notch1 signaling.
Journal: Journal of cellular biochemistry20110701
Title: Post-stroke hypothermia provides neuroprotection through inhibition of AMP-activated protein kinase.
Journal: Journal of neurotrauma20110701
Title: Anti-tumor effect of luteolin is accompanied by AMP-activated protein kinase and nuclear factor-κB modulation in HepG2 hepatocarcinoma cells.
Journal: International journal of molecular medicine20110701
Title: Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell.
Journal: Journal of cellular physiology20110701
Title: Berberine acutely activates the glucose transport activity of GLUT1.
Journal: Biochimie20110701
Title: Identification of new inhibitors of protein kinase R guided by statistical modeling.
Journal: Bioorganic & medicinal chemistry letters20110701
Title: Adiponectin protects rat hippocampal neurons against excitotoxicity.
Journal: Age (Dordrecht, Netherlands)20110601
Title: Inhibition of AMPK-associated autophagy enhances caffeic acid phenethyl ester-induced cell death in C6 glioma cells.
Journal: Planta medica20110601
Title: Novel role of AMP-activated protein kinase signaling in cigarette smoke induction of IL-8 in human lung epithelial cells and lung inflammation in mice.
Journal: Free radical biology & medicine20110601
Title: Possible functions of Dpp in gastropod shell formation and shell coiling.
Journal: Development genes and evolution20110601
Title: Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation.
Journal: Acta pharmacologica Sinica20110501
Title: Cinnamaldehyde prevents adipocyte differentiation and adipogenesis via regulation of peroxisome proliferator-activated receptor-γ (PPARγ) and AMP-activated protein kinase (AMPK) pathways.
Journal: Journal of agricultural and food chemistry20110427
Title: Dorsomorphin promotes human embryonic stem cell self-renewal.
Journal: Angewandte Chemie (International ed. in English)20110404
Title: Fenofibrate suppresses microvascular inflammation and apoptosis through adenosine monophosphate-activated protein kinase activation.
Journal: Metabolism: clinical and experimental20110401
Title: Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic mice.
Journal: British journal of pharmacology20110401
Title: Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcification.
Journal: Tissue engineering. Part A20110401
Title: Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway.
Journal: The Journal of pharmacology and experimental therapeutics20110401
Title: Leptin controls ketone body utilization in hypothalamic neuron.
Journal: Neuroscience letters20110303
Title: BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells.
Journal: Cell death and differentiation20110201
Title: Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation.
Journal: Cardiovascular research20110201
Title: Metformin decreases GnRH- and activin-induced gonadotropin secretion in rat pituitary cells: potential involvement of adenosine 5' monophosphate-activated protein kinase (PRKA).
Journal: Biology of reproduction20110201
Title: Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells.
Journal: Journal of neuroscience research20110201
Title: Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L.
Journal: The Journal of biological chemistry20110107
Title: Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.
Journal: Autophagy20110101
Title: Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival.
Journal: American journal of physiology. Heart and circulatory physiology20110101
Title: Detection of signaling effector-complexes downstream of bmp4 using PLA, a proximity ligation assay.
Journal: Journal of visualized experiments : JoVE20110101
Title: Biomechanical forces exert anabolic effects on osteoblasts by activation of SMAD 1/5/8 through type 1 BMP receptor.
Journal: Biorheology20110101
Title: The CPT1C 5'UTR contains a repressing upstream open reading frame that is regulated by cellular energy availability and AMPK.
Journal: PloS one20110101
Title: meso-Dihydroguaiaretic acid inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
Journal: Biological & pharmaceutical bulletin20110101
Title: Potentiation of neuronal insulin signaling and glucose uptake by resveratrol: the involvement of AMPK.
Journal: Pharmacological reports : PR20110101
Title: Small molecule promoted feeder free and adherent differentiation of functional neurons from human embryonic and induced pluripotent stem cells.
Journal: Journal of stem cells20110101
Title: Astrocyte elevated gene-1 induces protective autophagy.
Journal: Proceedings of the National Academy of Sciences of the United States of America20101221
Title: Calcitonin gene-related peptide promotes angiogenesis via AMP-activated protein kinase.
Journal: American journal of physiology. Cell physiology20101201
Title: Differential roles of AMPKα1 and AMPKα2 in regulating 4-HNE-induced RPE cell death and permeability.
Journal: Experimental eye research20101201
Title: The rational design of a novel potent analogue of the 5'-AMP-activated protein kinase inhibitor compound C with improved selectivity and cellular activity.
Journal: Bioorganic & medicinal chemistry letters20101115
Title: AMP-activated protein kinase is required for induction of apoptosis and epithelial-to-mesenchymal transition.
Journal: Cellular signalling20101101
Title: Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells.
Journal: The international journal of biochemistry & cell biology20101101
Title: AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts.
Journal: Bone20101101
Title: A role for AMPK in increased insulin action after serum starvation.
Journal: American journal of physiology. Cell physiology20101101
Title: Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice.
Journal: Biochemical and biophysical research communications20101008
Title: Adiponectin-mediated heme oxygenase-1 induction protects against iron-induced liver injury via a PPARα dependent mechanism.
Journal: The American journal of pathology20101001
Title: High-efficiency induction of neural conversion in human ESCs and human induced pluripotent stem cells with a single chemical inhibitor of transforming growth factor beta superfamily receptors.
Journal: Stem cells (Dayton, Ohio)20101001
Title: Role of AMPK throughout meiotic maturation in the mouse oocyte: evidence for promotion of polar body formation and suppression of premature activation.
Journal: Molecular reproduction and development20101001
Title: Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells.
Journal: International journal of radiation oncology, biology, physics20100901
Title: Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists.
Journal: British journal of pharmacology20100901
Title: Identification of early requirements for preplacodal ectoderm and sensory organ development.
Journal: PLoS genetics20100901
Title: Rosiglitazone inhibits monocyte/macrophage adhesion through de novo adiponectin production in human monocytes.
Journal: Journal of cellular biochemistry20100815
Title: AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha and nuclear respiratory factor 1 expression in rat visual cortical neurons.
Journal: Neuroscience20100811
Title: Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1.
Journal: Experimental cell research20100801
Title: A pharmacological activator of AMP-activated protein kinase protects hypoxic neurons in a concentration-dependent manner.
Journal: Neurochemical research20100801
Title: AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARalpha, but not PPARgamma, in rat insulinoma cell line INS-1.
Journal: Acta pharmacologica Sinica20100801
Title: The antioxidant effects of genistein are associated with AMP-activated protein kinase activation and PTEN induction in prostate cancer cells.
Journal: Journal of medicinal food20100801
Title: [Genetic basis for skeletal disease. Establishment of novel treatments for fibrodysplasia ossificans progressiva (FOP)].
Journal: Clinical calcium20100801
Title: Inhibition of AMP-activated protein kinase pathway sensitizes human leukemia K562 cells to nontoxic concentration of doxorubicin.
Journal: Molecular and cellular biochemistry20100701
Title: Adenosine monophosphate activated protein kinase regulates ABCG1-mediated oxysterol efflux from endothelial cells and protects against hypercholesterolemia-induced endothelial dysfunction.
Journal: Arteriosclerosis, thrombosis, and vascular biology20100701
Title: SU11248 (sunitinib) directly inhibits the activity of mammalian 5'-AMP-activated protein kinase (AMPK).
Journal: Cancer biology & therapy20100701
Title: Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro.
Journal: Acta pharmacologica Sinica20100701
Title: Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the muscle microcirculation increases nitric oxide synthesis and microvascular perfusion.
Journal: Arteriosclerosis, thrombosis, and vascular biology20100601
Title: Metformin-induced regulation of the intestinal D-glucose transporters.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20100601
Title: Acadesine inhibits tissue factor induction and thrombus formation by activating the phosphoinositide 3-kinase/Akt signaling pathway.
Journal: Arteriosclerosis, thrombosis, and vascular biology20100501
Title: AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.
Journal: The Journal of biological chemistry20100319
Title: Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.
Journal: Oncogene20100318
Title: BMP Inhibition with dorsomorphin limits adipogenic potential of preadipocytes.
Journal: The Journal of veterinary medical science20100301
Title: In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors.
Journal: ACS chemical biology20100219
Title: Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation.
Journal: Journal of agricultural and food chemistry20100210
Title: Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype.
Journal: Cardiovascular research20100201
Title: Expression and role of adiponectin receptor 1 in lipopolysaccharide-induced proliferation of cultured rat adventitial fibroblasts.
Journal: Cell biology international20100201
Title: BMP4 regulates vascular progenitor development in human embryonic stem cells through a Smad-dependent pathway.
Journal: Journal of cellular biochemistry20100201
Title: Metformin increases phagocytosis and acidifies lysosomal/endosomal compartments in AMPK-dependent manner in rat primary microglia.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20100201
Title: Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction.
Journal: Cardiovascular drugs and therapy20100201
Title: Beta-adrenergic-AMPK pathway phosphorylates acetyl-CoA carboxylase in a high-epinephrine rat model, SPORTS.
Journal: Obesity (Silver Spring, Md.)20100101
Title: Bone morphogenetic protein receptors and signal transduction.
Journal: Journal of biochemistry20100101
Title: AICAR (5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside) increases the production of toxic molecules and affects the profile of cytokines release in LPS-stimulated rat primary microglial cultures.
Journal: Neurotoxicology20100101
Title: Ambivalent effects of compound C (dorsomorphin) on inflammatory response in LPS-stimulated rat primary microglial cultures.
Journal: Naunyn-Schmiedeberg's archives of pharmacology20100101
Title: The novel function of nesfatin-1: anti-hyperglycemia.
Journal: Biochemical and biophysical research communications20100101
Title: Suppression effects of AICAR on insulin secretion involved in peroxisome proliferator-activated receptor gamma changes in INS-1 cells.
Journal: Journal of endocrinological investigation20100101
Title: Metabolic regulation of neuronal plasticity by the energy sensor AMPK.
Journal: PloS one20100101
Title: The role of hypothalamic AMP-activated protein kinase in ovariectomy-induced obesity in rats.
Journal: Menopause (New York, N.Y.)20100101
Title: The zebrafish embryo as a model for assessing off-target drug effects.
Journal: Disease models & mechanisms20100101
Title: Metformin has adenosine-monophosphate activated protein kinase (AMPK)-independent effects on LPS-stimulated rat primary microglial cultures.
Journal: Pharmacological reports : PR20100101
Title: Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells.
Journal: Atherosclerosis20091201
Title: AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.
Journal: Journal of lipid research20091201
Title: AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase.
Journal: American journal of physiology. Cell physiology20091201
Title: Adiponectin downregulates galectin-3 whose cellular form is elevated whereas its soluble form is reduced in type 2 diabetic monocytes.
Journal: FEBS letters20091119
Title: Adenosine monophosphate-activated protein kinase inhibits cardiac hypertrophy through reactivating peroxisome proliferator-activated receptor-alpha signaling pathway.
Journal: European journal of pharmacology20091012
Title: Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway.
Journal: Molecular pharmacology20091001
Title: Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin.
Journal: Cell host & microbe20090917
Title: Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner.
Journal: Hepatology (Baltimore, Md.)20090901
Title: Central AMPK contributes to sleep homeostasis in mice.
Journal: Neuropharmacology20090901
Title: Eicosapentaenoic acid stimulates AMP-activated protein kinase and increases visfatin secretion in cultured murine adipocytes.
Journal: Clinical science (London, England : 1979)20090814
Title: The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.
Journal: Proceedings of the National Academy of Sciences of the United States of America20090804
Title: Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations.
Journal: Endocrinology20090801
Title: AMPK inhibits myoblast differentiation through a PGC-1alpha-dependent mechanism.
Journal: American journal of physiology. Endocrinology and metabolism20090801
Title: Kidney bean husk extracts exert antitumor effect by inducing apoptosis involving AMP-activated protein kinase signaling pathway.
Journal: Annals of the New York Academy of Sciences20090801
Title: Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells.
Journal: Annals of the New York Academy of Sciences20090801
Title: Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR-induced AMPK activation.
Journal: Obesity (Silver Spring, Md.)20090701
Title: AMP-activated protein kinase influences metabolic remodeling in H9c2 cells hypertrophied by arginine vasopressin.
Journal: American journal of physiology. Heart and circulatory physiology20090601
Title: AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C.
Journal: Biochemical pharmacology20090601
Title: Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.
Journal: Circulation20090519
Title: Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose.
Journal: American journal of physiology. Endocrinology and metabolism20090501
Title: Regulation of erythrocyte survival by AMP-activated protein kinase.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20090401
Title: AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin.
Journal: Experimental & molecular medicine20090331
Title: Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva.
Journal: The Journal of biological chemistry20090313
Title: AMP-activated protein kinase is involved in neural stem cell growth suppression and cell cycle arrest by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and glucose deprivation by down-regulating phospho-retinoblastoma protein and cyclin D.
Journal: The Journal of biological chemistry20090306
Title: Regulation of Cl(-) secretion by AMPK in vivo.
Journal: Pflugers Archiv : European journal of physiology20090301
Title: AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633.
Journal: Circulation research20090227
Title: Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells.
Journal: Biochemical and biophysical research communications20090227
Title: Caloric restriction stimulates revascularization in response to ischemia via adiponectin-mediated activation of endothelial nitric-oxide synthase.
Journal: The Journal of biological chemistry20090116
Title: Applications of small molecule BMP inhibitors in physiology and disease.
Journal: Cytokine & growth factor reviews20090101
Title: A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor.
Journal: Biochemical and biophysical research communications20081219
Title: Differential regulation of AMP-activated kinase and AKT kinase in response to oxygen availability in crucian carp (Carassius carassius).
Journal: American journal of physiology. Regulatory, integrative and comparative physiology20081201
Title: AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells.
Journal: Oncology reports20081201
Title: BMP type I receptor inhibition reduces heterotopic [corrected] ossification.
Journal: Nature medicine20081201
Title: Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated kinase activity.
Journal: Regulatory peptides20081129
Title: Leptin reduces Alzheimer's disease-related tau phosphorylation in neuronal cells.
Journal: Biochemical and biophysical research communications20081121
Title: Compound C inhibits clonal expansion of preadipocytes by increasing p21 level irrespectively of AMPK inhibition.
Journal: Archives of biochemistry and biophysics20081101
Title: AMP-activated protein kinase and hypoxic pulmonary vasoconstriction.
Journal: European journal of pharmacology20081024
Title: AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology20081001
Title: Effects of an AMP-activated protein kinase inhibitor, compound C, on adipogenic differentiation of 3T3-L1 cells.
Journal: Biological & pharmaceutical bulletin20080901
Title: In vitro metformin anti-neoplastic activity in epithelial ovarian cancer.
Journal: Gynecologic oncology20080801
Title: Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors.
Journal: Bioorganic & medicinal chemistry letters20080801
Title: Small molecule antagonizes autoinhibition and activates AMP-activated protein kinase in cells.
Journal: The Journal of biological chemistry20080606
Title: Activation of AMP-activated protein kinase, inhibition of pyruvate dehydrogenase activity, and redistribution of substrate partitioning mediate the acute insulin-sensitizing effects of troglitazone in skeletal muscle cells.
Journal: Journal of cellular physiology20080501
Title: Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation.
Journal: Molecular and cellular endocrinology20080326
Title: AMP-activated protein kinase phosphorylates transcription factors of the CREB family.
Journal: Journal of applied physiology (Bethesda, Md. : 1985)20080201
Title: Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism.
Journal: Nature chemical biology20080101
Title: Small-molecule dissection of BMP signaling.
Journal: Nature chemical biology20080101
Title: Macropinocytosis is decreased in diabetic mouse macrophages and is regulated by AMPK.
Journal: BMC immunology20080101
Title: Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells.
Journal: PloS one20080101
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal20071215
Title: Compound C inhibits hypoxic activation of HIF-1 independent of AMPK.
Journal: FEBS letters20071211
Title: The relationship between p38 mitogen-activated protein kinase and AMP-activated protein kinase during myocardial ischemia.
Journal: Cardiovascular research20071201
Title: Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line.
Journal: American journal of physiology. Endocrinology and metabolism20071201
Title: Rosiglitazone reduces glucose-induced oxidative stress mediated by NAD(P)H oxidase via AMPK-dependent mechanism.
Journal: Arteriosclerosis, thrombosis, and vascular biology20071201
Title: Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling.
Journal: American journal of physiology. Endocrinology and metabolism20071201
Title: Nicotine-induced activation of AMP-activated protein kinase inhibits fatty acid synthase in 3T3L1 adipocytes: a role for oxidant stress.
Journal: The Journal of biological chemistry20070914
Title: Possible role of 5'AMP-activated protein kinase in the metformin-mediated arrest of bovine oocytes at the germinal vesicle stage during in vitro maturation.
Journal: Biology of reproduction20070901
Title: Resveratrol stimulates AMP kinase activity in neurons.
Journal: Proceedings of the National Academy of Sciences of the United States of America20070424
Title: Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway.
Journal: Cancer letters20070308
Title: Critical role of 5'-AMP-activated protein kinase in the stimulation of glucose transport in response to inhibition of oxidative phosphorylation.
Journal: American journal of physiology. Cell physiology20070101
Title: The changing AMPK expression profile in differentiating mouse skeletal muscle myoblast cells helps confer increasing resistance to apoptosis.
Journal: Experimental physiology20070101
Title: Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity.
Journal: Diabetologia20070101
Title: AMP-activated protein kinase and the regulation of autophagic proteolysis.
Journal: The Journal of biological chemistry20061117
Title: Role of AMP-activated protein kinase in mechanism of metformin action.
Journal: The Journal of clinical investigation20011015
Title: Noncanonical BMP signaling regulates cyclooxygenase-2 transcription.
Journal: Molecular endocrinology (Baltimore, Md.)
