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87-32-1,MFCD00005644
Catalog No.:AA003SM3

87-32-1 | N-Acetyl-DL-Tryptophan

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1g
>98.0%(T)(HPLC)
in stock  
$19.00   $13.00
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5g
98%(HPLC)
in stock  
$24.00   $17.00
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25g
98%
in stock  
$33.00   $23.00
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100g
98%
in stock  
$78.00   $55.00
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500g
98%
in stock  
$311.00   $218.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003SM3
Chemical Name:
N-Acetyl-DL-Tryptophan
CAS Number:
87-32-1
Molecular Formula:
C13H14N2O3
Molecular Weight:
246.2619
MDL Number:
MFCD00005644
SMILES:
CC(=O)NC(C(=O)O)Cc1c[nH]c2c1cccc2
Properties
Properties
 
BP:
586.6°C at 760 mmHg  
Form:
Solid  
MP:
204-206 °C (dec.)(lit.)  
Refractive Index:
1.6450 (estimate)  
Storage:
Room Temperature;Light sensitive;Inert atmosphere;  

Computed Properties
 
Complexity:
332  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.1  

Downstream Synthesis Route

[1]Snyder;MacDonald[JournaloftheAmericanChemicalSociety,1955,vol.77,p.1257,1258]

[1]Snyder;Smith[JournaloftheAmericanChemicalSociety,1944,vol.66,p.350]Hellmann;Lingens[Hoppe-Seyler'sZeitschriftfurPhysiologischeChemie,1954,vol.297,p.283,285]

[1]Snyder;Smith[JournaloftheAmericanChemicalSociety,1944,vol.66,p.350]

[2]CurrentPatentAssignee:DOWINC-US2847420,1953,A

[1]duVigneaud;Sealock[JournalofBiologicalChemistry,1932,vol.96,p.511,512,514]

[2]Berg;Rose;Marvel[JournalofBiologicalChemistry,1930,vol.85,p.209]

[3]Kolb;Toennies[JournalofBiologicalChemistry,1942,vol.144,p.195,197]

[1]Albertson[JournaloftheAmericanChemicalSociety,1951,vol.73,p.452]

Literature

Title: Ultrafast dynamics of nonequilibrium electron transfer in photoinduced redox cycle: solvent mediation and conformation flexibility.

Journal: The journal of physical chemistry. B 20120802

Title: Substance P-induced changes in cell genesis following diffuse traumatic brain injury.

Journal: Neuroscience 20120712

Title: Treatment with a substance P receptor antagonist is neuroprotective in the intrastriatal 6-hydroxydopamine model of early Parkinson's disease.

Journal: PloS one 20120101

Title: Characterization of N-acetyltryptophan degradation products in concentrated human serum albumin solutions and development of an automated high performance liquid chromatography-mass spectrometry method for their quantitation.

Journal: Journal of chromatography. A 20111014

Title: A substance P antagonist improves outcome when administered 4 h after onset of ischaemic stroke.

Journal: Brain research 20110601

Title: Industrial stabilizers caprylate and N-acetyltryptophanate reduce the efficacy of albumin in liver patients.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20110601

Title: One-step preparation of S-nitrosated human serum albumin with high biological activities.

Journal: Nitric oxide : biology and chemistry 20100915

Title: Infusions of albumin increase free fraction of naproxen in healthy volunteers: a randomized crossover study.

Journal: Acta anaesthesiologica Scandinavica 20100401

Title: Substance P is associated with the development of brain edema and functional deficits after traumatic brain injury.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090801

Title: Electron transfer between guanosine radicals and amino acids in aqueous solution. II. Reduction of guanosine radicals by tryptophan.

Journal: The journal of physical chemistry. B 20080306

Title: Infusion of albumin attenuates changes in serum protein binding of drugs in surgical patients compared with volume replacement with HAES.

Journal: Acta anaesthesiologica Scandinavica 20080301

Title: Electron transfer from aromatic amino acids to triplet quinones.

Journal: Journal of photochemistry and photobiology. B, Biology 20070925

Title: 15N-CIDNP investigations during tryptophan, N-acetyl-L-tryptophan, and melatonin nitration with reactive nitrogen species.

Journal: Free radical research 20070501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Stabilizing mechanisms in commercial albumin preparations: octanoate and N-acetyl-L-tryptophanate protect human serum albumin against heat and oxidative stress.

Journal: Biochimica et biophysica acta 20041001

Title: A substance P antagonist increases brain intracellular free magnesium concentration after diffuse traumatic brain injury in rats.

Journal: Journal of the American College of Nutrition 20041001

Title: Degradation of N-acetyl tryptophan by low-energy (<12 eV) electrons.

Journal: Journal of the American Chemical Society 20040929

Title: Nitration and nitrosation of N-acetyl-L-tryptophan and tryptophan residues in proteins by various reactive nitrogen species.

Journal: Free radical biology & medicine 20040901

Title: Pharmaceutical-grade albumin: impaired drug-binding capacity in vitro.

Journal: BMC clinical pharmacology 20040101

Title: More chemistry of the thaxtomin phytotoxins.

Journal: Phytochemistry 20031101

Title: Interpretation of fluorescence decays using a power-like model.

Journal: Biophysical journal 20030701

Title: Regiospecific nitrosation of N-terminal-blocked tryptophan derivatives by N2O3 at physiological pH.

Journal: The Journal of biological chemistry 20030404

Title: Isolation of bovine plasma albumin by liquid chromatography and its polymerization for use in immunohematology.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010801

Title: Intra and intermolecular charge effects on the reaction of the superoxide radical anion with semi-oxidized tryptophan in peptides and N-acetyl tryptophan.

Journal: Free radical research 19981101

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Tags:87-32-1 Molecular Formula|87-32-1 MDL|87-32-1 SMILES|87-32-1 N-Acetyl-DL-Tryptophan