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Home Fluorides 871224-64-5
871224-64-5,MFCD22419385
Catalog No.:AA00GTY0

871224-64-5 | 2(1H)-Isoquinolineacetamide,3,4-dihydro-6,7-dimethoxy-N-methyl-a-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-, (aR,1S)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98% by HPLC
in stock  
$289.00   $202.00
- +
10mg
98% by HPLC
in stock  
$444.00   $311.00
- +
25mg
98% by HPLC
in stock  
$868.00   $608.00
- +
50mg
98% by HPLC
in stock  
$1,434.00   $1,004.00
- +
100mg
98% by HPLC
in stock  
$2,435.00   $1,705.00
- +
500mg
98% by HPLC
in stock  
$7,722.00   $5,405.00
- +
1000mg
98% by HPLC
in stock  
$12,318.00   $8,623.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GTY0
Chemical Name:
2(1H)-Isoquinolineacetamide,3,4-dihydro-6,7-dimethoxy-N-methyl-a-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-, (aR,1S)-
CAS Number:
871224-64-5
Molecular Formula:
C29H31F3N2O3
Molecular Weight:
512.5632
MDL Number:
MFCD22419385
SMILES:
CNC(=O)C(N1CCc2c(C1CCc1ccc(cc1)C(F)(F)F)cc(c(c2)OC)OC)c1ccccc1
Properties
Computed Properties
 
Complexity:
722  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
8  
XLogP3:
6  

Literature

Title: Dayot S, et al. In vitro, in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma. Oncotarget. 2018 Jan 9;9(6):6952-6967.

Title: Malherbe P, et al. Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with selective OX1 and OX2 antagonists. Mol Pharmacol. 2009 Sep;76(3):618-31.

Title: Black SW, et al. Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy. Sleep. 2013 Mar 1;36(3):325-36.

Title: Dietrich H, et al. Intact learning and memory in rats following treatment with the dual orexin receptor antagonist almorexant. Psychopharmacology (Berl). 2010 Oct;212(2):145-54.

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SDS
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Tags:871224-64-5 Molecular Formula|871224-64-5 MDL|871224-64-5 SMILES|871224-64-5 2(1H)-Isoquinolineacetamide,3,4-dihydro-6,7-dimethoxy-N-methyl-a-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-, (aR,1S)-