Home Other Building Blocks 873305-35-2
873305-35-2,MFCD22417088
Catalog No.:AA00GTXZ

873305-35-2 | Aim-100

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$9.00   $7.00
- +
5mg
98%
in stock  
$24.00   $17.00
- +
10mg
98%
in stock  
$34.00   $24.00
- +
50mg
98%
in stock  
$109.00   $76.00
- +
100mg
98%
in stock  
$169.00   $118.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GTXZ
Chemical Name:
Aim-100
CAS Number:
873305-35-2
Molecular Formula:
C23H21N3O2
Molecular Weight:
371.4317
MDL Number:
MFCD22417088
SMILES:
C1COC(C1)CNc1ncnc2c1c(c1ccccc1)c(o2)c1ccccc1
Properties
Computed Properties
 
Complexity:
492  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
5  

Literature

Title: Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and preliminary SAR.

Journal: Bioorganic & medicinal chemistry letters 20070415

Title: Further studies on lipid-peroxide formation in isolated hepatocytes.

Journal: European journal of biochemistry 19751115

Title: Mahajan K, et al.Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Am J Pathol. 2012 Apr;180(4):1386-93.

Title: Mahajan K, et al. Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer. J Biol Chem. 2012 Jun 22;287(26):22112-22.

Title: Mahajan K, et al. Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity. Prostate. 2010 Sep 1;70(12):1274-85.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:873305-35-2 Molecular Formula|873305-35-2 MDL|873305-35-2 SMILES|873305-35-2 Aim-100