[1]Flygare,JohnA.;Beresini,Maureen;Budha,Nageshwar;Chan,Helen;Chan,IrisT.;Cheeti,Sravanthi;Cohen,Frederick;Deshayes,Kurt;Doerner,Karl;Eckhardt,S.Gail;Elliott,LindaO.;Feng,Bainian;Franklin,MatthewC.;Reisner,StacyFrankovitz;Gazzard,Lewis;Halladay,Jason;Hymowitz,SarahG.;La,Hank;Lorusso,Patricia;Maurer,Brigitte;Murray,Lesley;Plise,Emile;Quan,Clifford;Stephan,Jean-Philippe;Young,ShinG.;Tom,Jeffrey;Tsui,Vickie;Um,Joanne;Varfolomeev,Eugene;Vucic,Domagoj;Wagner,AndrewJ.;Wallweber,HeidiJ.A.;Wang,Lan;Ware,Joseph;Wen,Zhaoyang;Wong,Harvey;Wong,JonathanM.;Wong,Melisa;Wong,Susan;Yu,Ron;Zobel,Kerry;Fairbrother,WayneJ.[JournalofMedicinalChemistry,2012,vol.55,#9,p.4101-4113]
[1]Locationinpatent:experimentalpartFlygare,JohnA.;Beresini,Maureen;Budha,Nageshwar;Chan,Helen;Chan,IrisT.;Cheeti,Sravanthi;Cohen,Frederick;Deshayes,Kurt;Doerner,Karl;Eckhardt,S.Gail;Elliott,LindaO.;Feng,Bainian;Franklin,MatthewC.;Reisner,StacyFrankovitz;Gazzard,Lewis;Halladay,Jason;Hymowitz,SarahG.;La,Hank;Lorusso,Patricia;Maurer,Brigitte;Murray,Lesley;Plise,Emile;Quan,Clifford;Stephan,Jean-Philippe;Young,ShinG.;Tom,Jeffrey;Tsui,Vickie;Um,Joanne;Varfolomeev,Eugene;Vucic,Domagoj;Wagner,AndrewJ.;Wallweber,HeidiJ.A.;Wang,Lan;Ware,Joseph;Wen,Zhaoyang;Wong,Harvey;Wong,JonathanM.;Wong,Melisa;Wong,Susan;Yu,Ron;Zobel,Kerry;Fairbrother,WayneJ.[JournalofMedicinalChemistry,2012,vol.55,#9,p.4101-4113]
[1]Flygare,JohnA.;Beresini,Maureen;Budha,Nageshwar;Chan,Helen;Chan,IrisT.;Cheeti,Sravanthi;Cohen,Frederick;Deshayes,Kurt;Doerner,Karl;Eckhardt,S.Gail;Elliott,LindaO.;Feng,Bainian;Franklin,MatthewC.;Reisner,StacyFrankovitz;Gazzard,Lewis;Halladay,Jason;Hymowitz,SarahG.;La,Hank;Lorusso,Patricia;Maurer,Brigitte;Murray,Lesley;Plise,Emile;Quan,Clifford;Stephan,Jean-Philippe;Young,ShinG.;Tom,Jeffrey;Tsui,Vickie;Um,Joanne;Varfolomeev,Eugene;Vucic,Domagoj;Wagner,AndrewJ.;Wallweber,HeidiJ.A.;Wang,Lan;Ware,Joseph;Wen,Zhaoyang;Wong,Harvey;Wong,JonathanM.;Wong,Melisa;Wong,Susan;Yu,Ron;Zobel,Kerry;Fairbrother,WayneJ.[JournalofMedicinalChemistry,2012,vol.55,#9,p.4101-4113]
[1]Flygare,JohnA.;Beresini,Maureen;Budha,Nageshwar;Chan,Helen;Chan,IrisT.;Cheeti,Sravanthi;Cohen,Frederick;Deshayes,Kurt;Doerner,Karl;Eckhardt,S.Gail;Elliott,LindaO.;Feng,Bainian;Franklin,MatthewC.;Reisner,StacyFrankovitz;Gazzard,Lewis;Halladay,Jason;Hymowitz,SarahG.;La,Hank;Lorusso,Patricia;Maurer,Brigitte;Murray,Lesley;Plise,Emile;Quan,Clifford;Stephan,Jean-Philippe;Young,ShinG.;Tom,Jeffrey;Tsui,Vickie;Um,Joanne;Varfolomeev,Eugene;Vucic,Domagoj;Wagner,AndrewJ.;Wallweber,HeidiJ.A.;Wang,Lan;Ware,Joseph;Wen,Zhaoyang;Wong,Harvey;Wong,JonathanM.;Wong,Melisa;Wong,Susan;Yu,Ron;Zobel,Kerry;Fairbrother,WayneJ.[JournalofMedicinalChemistry,2012,vol.55,#9,p.4101-4113]
[1]Flygare,JohnA.;Beresini,Maureen;Budha,Nageshwar;Chan,Helen;Chan,IrisT.;Cheeti,Sravanthi;Cohen,Frederick;Deshayes,Kurt;Doerner,Karl;Eckhardt,S.Gail;Elliott,LindaO.;Feng,Bainian;Franklin,MatthewC.;Reisner,StacyFrankovitz;Gazzard,Lewis;Halladay,Jason;Hymowitz,SarahG.;La,Hank;Lorusso,Patricia;Maurer,Brigitte;Murray,Lesley;Plise,Emile;Quan,Clifford;Stephan,Jean-Philippe;Young,ShinG.;Tom,Jeffrey;Tsui,Vickie;Um,Joanne;Varfolomeev,Eugene;Vucic,Domagoj;Wagner,AndrewJ.;Wallweber,HeidiJ.A.;Wang,Lan;Ware,Joseph;Wen,Zhaoyang;Wong,Harvey;Wong,JonathanM.;Wong,Melisa;Wong,Susan;Yu,Ron;Zobel,Kerry;Fairbrother,WayneJ.[JournalofMedicinalChemistry,2012,vol.55,#9,p.4101-4113]
Title: Toxicity profile of small-molecule IAP antagonist GDC-0152 is linked to TNF-α pharmacology.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130101
Title: Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).
Journal: Journal of medicinal chemistry 20120510
Title: Flygare JA, et al. Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). J Med Chem. 2012 May 10;55(9):4101-13.
