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875755-24-1,MFCD11045298
Catalog No.:AA008EQ8

875755-24-1 | NS8593 hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$42.00   $29.00
- +
5mg
≥98%
in stock  
$133.00   $93.00
- +
10mg
≥98%
in stock  
$246.00   $172.00
- +
25mg
≥98%
in stock  
$562.00   $393.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008EQ8
Chemical Name:
NS8593 hydrochloride
CAS Number:
875755-24-1
Molecular Formula:
C17H18ClN3
Molecular Weight:
299.7979
MDL Number:
MFCD11045298
SMILES:
c1ccc2c(c1)[C@@H](CCC2)Nc1nc2c([nH]1)cccc2.Cl
Properties
Computed Properties
 
Complexity:
332  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  

Literature

Title: Sørensen US, et al. Synthesis and structure-activity relationship studies of 2-(N-substituted)-aminobenzimidazoles as potent negative gating modulators ofsmall conductance Ca2+-activated K+ channels. J Med Chem. 2008 Dec 11;51(23):7625-34.

Title: Strøbaek D, et al. Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons. Mol Pharmacol. 2006 Nov;70(5):1771-82.

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SDS
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