87726-17-8,MFCD00865098
Catalog No.:AA004G8J

87726-17-8 | (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(((S)-1-(1-iminoethyl)pyrrolidin-3-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
95+%
1 week  
$1,679.00   $1,175.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA004G8J
Chemical Name:
(5R,6S)-6-((R)-1-Hydroxyethyl)-3-(((S)-1-(1-iminoethyl)pyrrolidin-3-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CAS Number:
87726-17-8
Molecular Formula:
C15H21N3O4S
Molecular Weight:
339.4099
MDL Number:
MFCD00865098
SMILES:
C[C@H]([C@H]1C(=O)N2[C@@H]1CC(=C2C(=O)O)S[C@H]1CCN(C1)C(=N)C)O
Properties
Properties
 
Form:
Solid  
MP:
>190°C (dec.)  
Storage:
Light sensitive;Keep in dry area;-20 ℃;Inert atmosphere;  

Computed Properties
 
Complexity:
606  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
0  

Literature

Title: Panipenem does not alter the pharmacokinetics of the active metabolite of irinotecan SN-38 and inactive metabolite SN-38 glucuronide (SN-38G) in rats.

Journal: Anticancer research 20110901

Title: Pulmonary nocardiosis caused by Nocardia exalbida complicating Pneumocystis pneumonia in an HIV-infected patient.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110801

Title: [Campylobacter jejuni meningitis in an immunocompetent adult male].

Journal: Rinsho shinkeigaku = Clinical neurology 20100401

Title: Cat scratch disease with encephalopathy in a 9-year-old girl.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20081201

Title: Simple and rapid determination of serum carbapenem concentrations by high-performance liquid chromatography.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080201

Title: [In-vitro activity of panipenem against clinical isolates in 2006].

Journal: The Japanese journal of antibiotics 20080201

Title: Parenteral carbapenems.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080101

Title: Panipenem versus cefepime as empirical monotherapy in adult cancer patients with febrile neutropenia: a prospective randomized trial.

Journal: Japanese journal of clinical oncology 20080101

Title: A case of osteopetrosis with acute optic neuropathy.

Journal: Japanese journal of ophthalmology 20080101

Title: [Seven cases of decreased serum valproic acid concentration during concomitant use of carbapenem antibiotics].

Journal: The Korean journal of laboratory medicine 20071001

Title: [Relationship between protein binding and antimicrobial activities of antibiotics against Streptococcus pneumoniae and Haemophilus influenzae].

Journal: The Japanese journal of antibiotics 20061001

Title: Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibiotics.

Journal: Toxicology 20060501

Title: Population pharmacokinetic analysis of panipenem/betamipron in patients with various degrees of renal function.

Journal: Chemotherapy 20060101

Title: Pharmacokinetics and the most suitable regimen of panipenem/beta mipron in critically ill patients receiving continuous renal replacement therapy: a pilot study.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20060101

Title: [A case of phlegmonous esophagogastritis improved with conservative therapy].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20051201

Title: Quantitative evaluation of effect of renal failure on the pharmacokinetics of panipenem in rats.

Journal: Biological & pharmaceutical bulletin 20051101

Title: Combined effects of panipenem and aminoglycosides on methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in vitro.

Journal: Chemotherapy 20051001

Title: Increased erythrocyte distribution of valproic acid in pharmacokinetic interaction with carbapenem antibiotics in rat and human.

Journal: Journal of pharmaceutical sciences 20050801

Title: Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.

Journal: Journal of pharmaceutical sciences 20050701

Title: [Surveillance of susceptibility of clinical isolates to panipenem between 2000 and 2003].

Journal: The Japanese journal of antibiotics 20050601

Title: Isomerization kinetics of panipenem in aqueous solution.

Journal: Chemical & pharmaceutical bulletin 20050501

Title: Pharmacokinetics of panipenem/betamipron in patients with end-stage renal disease.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20050201

Title: [Epidemiology of Streptococcus pneumoniae isolates in Gifu Prefecture].

Journal: The Japanese journal of antibiotics 20040401

Title: [Antimicrobial susceptibilities of Streptococcus pneumoniae and Haemophilus influenzae isolated from children with meningitis].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20040101

Title: [Activity of cephems and carbapenems against clinically isolated Mycobacterium abscessus].

Journal: Kekkaku : [Tuberculosis] 20030901

Title: Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns.

Journal: International journal of antimicrobial agents 20030801

Title: Effect of basic amino acids on susceptibility to carbapenems in clinical Pseudomonas aeruginosa isolates.

Journal: International journal of medical microbiology : IJMM 20030601

Title: [Antibacterial activity of panipenem against clinical isolates in 2000 and 2001].

Journal: The Japanese journal of antibiotics 20021201

Title: [Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999].

Journal: The Japanese journal of antibiotics 20020601

Title: [Antimicrobial activity of carbapenems and the combined effect with aminoglycoside against recent clinical isolates of Pseudomonas aeruginosa].

Journal: The Japanese journal of antibiotics 20020401

Title: [Rapid bactericidal activities of carbapenems against Pseudomonas aeruginosa in simulating human plasma concentrations].

Journal: The Japanese journal of antibiotics 20020401

Title: [Bactericidal activity of biapenem against various efflux system mutants of Pseudomonas aeruginosa].

Journal: The Japanese journal of antibiotics 20020201

Title: [Comparative antibacterial activity of carbapenems against P. aeruginosa (1)].

Journal: The Japanese journal of antibiotics 20011101

Title: [Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains].

Journal: The Japanese journal of antibiotics 20010901

Title: Population pharmacokinetics of panipenem in neonates and retrospective evaluation of dosage.

Journal: The Journal of antimicrobial chemotherapy 20010101

Title: Structural features resulting in convulsive activity of carbapenem compounds: effect of C-2 side chain.

Journal: The Journal of antibiotics 19950501

Title: Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex.

Journal: Japanese journal of pharmacology 19940901

Title: Immunogenicity and allergenicity studies on two beta-lactam structures, a clavam, clavulanic acid, and a carbapenem: structure-activity relationships.

Journal: International archives of allergy and applied immunology 19880101

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SDS
Tags:87726-17-8 Molecular Formula|87726-17-8 MDL|87726-17-8 SMILES|87726-17-8 (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(((S)-1-(1-iminoethyl)pyrrolidin-3-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Catalog No.: AA004G8J
87726-17-8,MFCD00865098
87726-17-8 | (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(((S)-1-(1-iminoethyl)pyrrolidin-3-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Pack Size: 10mg
Purity: 95+%
1 week
$1,679.00 $1,175.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA004G8J
Chemical Name: (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(((S)-1-(1-iminoethyl)pyrrolidin-3-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CAS Number: 87726-17-8
Molecular Formula: C15H21N3O4S
Molecular Weight: 339.4099
MDL Number: MFCD00865098
SMILES: C[C@H]([C@H]1C(=O)N2[C@@H]1CC(=C2C(=O)O)S[C@H]1CCN(C1)C(=N)C)O
Properties
Form: Solid  
MP: >190°C (dec.)  
Storage: Light sensitive;Keep in dry area;-20 ℃;Inert atmosphere;  
Complexity: 606  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 4  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 23  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 0  
Literature fold

Title: Panipenem does not alter the pharmacokinetics of the active metabolite of irinotecan SN-38 and inactive metabolite SN-38 glucuronide (SN-38G) in rats.

Journal: Anticancer research20110901

Title: Pulmonary nocardiosis caused by Nocardia exalbida complicating Pneumocystis pneumonia in an HIV-infected patient.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy20110801

Title: [Campylobacter jejuni meningitis in an immunocompetent adult male].

Journal: Rinsho shinkeigaku = Clinical neurology20100401

Title: Cat scratch disease with encephalopathy in a 9-year-old girl.

Journal: Pediatrics international : official journal of the Japan Pediatric Society20081201

Title: Simple and rapid determination of serum carbapenem concentrations by high-performance liquid chromatography.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy20080201

Title: [In-vitro activity of panipenem against clinical isolates in 2006].

Journal: The Japanese journal of antibiotics20080201

Title: Parenteral carbapenems.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases20080101

Title: Panipenem versus cefepime as empirical monotherapy in adult cancer patients with febrile neutropenia: a prospective randomized trial.

Journal: Japanese journal of clinical oncology20080101

Title: A case of osteopetrosis with acute optic neuropathy.

Journal: Japanese journal of ophthalmology20080101

Title: [Seven cases of decreased serum valproic acid concentration during concomitant use of carbapenem antibiotics].

Journal: The Korean journal of laboratory medicine20071001

Title: [Relationship between protein binding and antimicrobial activities of antibiotics against Streptococcus pneumoniae and Haemophilus influenzae].

Journal: The Japanese journal of antibiotics20061001

Title: Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibiotics.

Journal: Toxicology20060501

Title: Population pharmacokinetic analysis of panipenem/betamipron in patients with various degrees of renal function.

Journal: Chemotherapy20060101

Title: Pharmacokinetics and the most suitable regimen of panipenem/beta mipron in critically ill patients receiving continuous renal replacement therapy: a pilot study.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992)20060101

Title: [A case of phlegmonous esophagogastritis improved with conservative therapy].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology20051201

Title: Quantitative evaluation of effect of renal failure on the pharmacokinetics of panipenem in rats.

Journal: Biological & pharmaceutical bulletin20051101

Title: Combined effects of panipenem and aminoglycosides on methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa in vitro.

Journal: Chemotherapy20051001

Title: Increased erythrocyte distribution of valproic acid in pharmacokinetic interaction with carbapenem antibiotics in rat and human.

Journal: Journal of pharmaceutical sciences20050801

Title: Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.

Journal: Journal of pharmaceutical sciences20050701

Title: [Surveillance of susceptibility of clinical isolates to panipenem between 2000 and 2003].

Journal: The Japanese journal of antibiotics20050601

Title: Isomerization kinetics of panipenem in aqueous solution.

Journal: Chemical & pharmaceutical bulletin20050501

Title: Pharmacokinetics of panipenem/betamipron in patients with end-stage renal disease.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy20050201

Title: [Epidemiology of Streptococcus pneumoniae isolates in Gifu Prefecture].

Journal: The Japanese journal of antibiotics20040401

Title: [Antimicrobial susceptibilities of Streptococcus pneumoniae and Haemophilus influenzae isolated from children with meningitis].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases20040101

Title: [Activity of cephems and carbapenems against clinically isolated Mycobacterium abscessus].

Journal: Kekkaku : [Tuberculosis]20030901

Title: Alterations in penicillin binding protein gene of Streptococcus pneumoniae and their correlation with susceptibility patterns.

Journal: International journal of antimicrobial agents20030801

Title: Effect of basic amino acids on susceptibility to carbapenems in clinical Pseudomonas aeruginosa isolates.

Journal: International journal of medical microbiology : IJMM20030601

Title: [Antibacterial activity of panipenem against clinical isolates in 2000 and 2001].

Journal: The Japanese journal of antibiotics20021201

Title: [Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999].

Journal: The Japanese journal of antibiotics20020601

Title: [Antimicrobial activity of carbapenems and the combined effect with aminoglycoside against recent clinical isolates of Pseudomonas aeruginosa].

Journal: The Japanese journal of antibiotics20020401

Title: [Rapid bactericidal activities of carbapenems against Pseudomonas aeruginosa in simulating human plasma concentrations].

Journal: The Japanese journal of antibiotics20020401

Title: [Bactericidal activity of biapenem against various efflux system mutants of Pseudomonas aeruginosa].

Journal: The Japanese journal of antibiotics20020201

Title: [Comparative antibacterial activity of carbapenems against P. aeruginosa (1)].

Journal: The Japanese journal of antibiotics20011101

Title: [Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains].

Journal: The Japanese journal of antibiotics20010901

Title: Population pharmacokinetics of panipenem in neonates and retrospective evaluation of dosage.

Journal: The Journal of antimicrobial chemotherapy20010101

Title: Structural features resulting in convulsive activity of carbapenem compounds: effect of C-2 side chain.

Journal: The Journal of antibiotics19950501

Title: Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex.

Journal: Japanese journal of pharmacology19940901

Title: Immunogenicity and allergenicity studies on two beta-lactam structures, a clavam, clavulanic acid, and a carbapenem: structure-activity relationships.

Journal: International archives of allergy and applied immunology19880101

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