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Home Other Building Blocks 878739-06-1
878739-06-1,MFCD17392577
Catalog No.:AA00GTYC

878739-06-1 | AZ 628

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
99%(HPLC)
in stock  
$86.00   $60.00
- +
10mg
99%(HPLC)
in stock  
$154.00   $108.00
- +
25mg
99%(HPLC)
in stock  
$308.00   $216.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GTYC
Chemical Name:
AZ 628
CAS Number:
878739-06-1
Molecular Formula:
C27H25N5O2
Molecular Weight:
451.5197
MDL Number:
MFCD17392577
SMILES:
N#CC(c1cccc(c1)C(=O)Nc1ccc(c(c1)Nc1ccc2c(c1)c(=O)n(cn2)C)C)(C)C
Properties
Computed Properties
 
Complexity:
845  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
4.2  

Literature

Title: Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.

Journal: Bioorganic & medicinal chemistry letters 20140415

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters 20130801

Title: Selective Raf inhibition in cancer therapy.

Journal: Expert opinion on therapeutic targets 20071201

Title: Khazak V, et al. Selective Raf inhibition in cancer therapy. Expert Opin Ther Targets. 2007 Dec;11(12):1587-609.

Title: Lau KS, et al. BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner. PLoS One. 2012;7(7):e41343.

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Tags:878739-06-1 Molecular Formula|878739-06-1 MDL|878739-06-1 SMILES|878739-06-1 AZ 628