Title: Orally administered berberine ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting activation of PPAR-γ and subsequent expression of HGF in colons.
Journal: Toxicology and applied pharmacology 20180315
Title: Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.
Journal: Scientific reports 20180101
Title: Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust.
Journal: Environmental science & technology 20150818
Title: Rosiglitzone suppresses angiotensin II-induced production of KLF5 and cell proliferation in rat vascular smooth muscle cells.
Journal: PloS one 20150101
Title: Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.
Journal: Antioxidants & redox signaling 20140520
Title: Antimycotics suppress the Malassezia extract-induced production of CXC chemokine ligand 10 in human keratinocytes.
Journal: The Journal of dermatology 20140201
Title: PPARγ agonists regulate tobacco smoke-induced Toll like receptor 4 expression in alveolar macrophages.
Journal: Respiratory research 20140101
Title: Prostaglandin D2 toxicity in primary neurons is mediated through its bioactive cyclopentenone metabolites.
Journal: Neurotoxicology 20131201
Title: Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib.
Journal: Journal of lipid research 20131101
Title: Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes.
Journal: Journal of dermatological science 20130901
Title: Evidence for a luteotropic role of peroxisome proliferator-activated receptor gamma: expression and in vitro effects on enzymatic and hormonal activities in corpora lutea of pseudopregnant rabbits.
Journal: Biology of reproduction 20130301
Title: COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.
Journal: Molecular cancer therapeutics 20130101
Title: Sodium dodecyl sulfate and sodium dodecyl benzenesulfonate are ligands for peroxisome proliferator-activated receptor γ.
Journal: The Journal of toxicological sciences 20130101
Title: Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.
Journal: The Journal of biological chemistry 20121102
Title: Exploring the cyclooxygenase 2 (COX2)/15d-Δ(12,14)PGJ(2) system in hamster Sertoli cells: regulation by FSH/testosterone and relevance to glucose uptake.
Journal: General and comparative endocrinology 20121101
Title: 15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells.
Journal: The Journal of pharmacology and experimental therapeutics 20120901
Title: Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression.
Journal: The Journal of biological chemistry 20120706
Title: The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ¹²,¹⁴-prostaglandin J₂-treated endothelial cells.
Journal: Free radical biology & medicine 20120501
Title: 15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes.
Journal: Free radical biology & medicine 20120315
Title: High sodium butyrate levels induce MDR1 activation in colorectal cells: Impact of 15-deoxy-Δ(12,14)-prostaglandin J(2) on the resistance to saquinavir.
Journal: Biochemical and biophysical research communications 20120224
Title: 15-Deoxy-Δ(12,14)-prostaglandin J2 exerts pro- and anti-inflammatory effects in mesangial cells in a concentration-dependent manner.
Journal: Inflammation & allergy drug targets 20120201
Title: Changes in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J2.
Journal: Mediators of inflammation 20120101
Title: Transcription of liver X receptor is down-regulated by 15-deoxy-Δ(12,14)-prostaglandin J(2) through oxidative stress in human neutrophils.
Journal: PloS one 20120101
Title: 15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts.
Journal: Journal of cellular physiology 20111201
Title: Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells.
Journal: Chemical research in toxicology 20110815
Title: Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthase in macrophages is mediated through the activation of peroxisome proliferator-activated receptor (PPAR) gamma.
Journal: The Journal of biological chemistry 20110805
Title: 15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes.
Journal: Prostaglandins & other lipid mediators 20110801
Title: 15-Deoxy-Δ12,14-prostaglandin J2 enhanced the anti-tumor activity of camptothecin against renal cell carcinoma independently of topoisomerase-II and PPARγ pathways.
Journal: Biochemical and biophysical research communications 20110708
Title: Stable reporter cell lines for peroxisome proliferator-activated receptor γ (PPARγ)-mediated modulation of gene expression.
Journal: Analytical biochemistry 20110701
Title: 15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma.
Journal: Molecular pharmacology 20110701
Title: Effects of 15-deoxy-∆¹²,¹⁴-prostaglandin J₂ on the production of IL-8 and the expression of Toll-like receptor 2 in human primary keratinocytes stimulated with lipopolysaccharide.
Journal: Molecular biology reports 20110601
Title: Role of NF-kappaB and PPAR-gamma in lung inflammation induced by monocyte-derived microparticles.
Journal: The European respiratory journal 20110601
Title: Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists.
Journal: Brain, behavior, and immunity 20110601
Title: EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells.
Journal: Biochemical pharmacology 20110501
Title: 15-deoxy-D12,14-prostaglandin J2 suppresses RANTES expression by inhibiting NADPH oxidase activation in Helicobacter pylori-infected gastric epithelial cells.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110401
Title: Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs.
Journal: Journal of cellular biochemistry 20110201
Title: Tanshinone IIA attenuates atherosclerosis in ApoE(-/-) mice through down-regulation of scavenger receptor expression.
Journal: European journal of pharmacology 20110110
Title: Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo.
Journal: Journal of lipid research 20110101
Title: Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20110101
Title: Proteomic identification of protein targets for 15-deoxy-Δ(12,14)-prostaglandin J2 in neuronal plasma membrane.
Journal: PloS one 20110101
Title: Anticancer effects of 15d-prostaglandin-J2 in wild-type and doxorubicin-resistant ovarian cancer cells: novel actions on SIRT1 and HDAC.
Journal: PloS one 20110101
Title: 15-Deoxy-Δ¹²,¹⁴ prostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice.
Journal: PloS one 20110101
Title: Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2.
Journal: PloS one 20110101
Title: Expression of TREM-1 is inhibited by PGD2 and PGJ2 in macrophages.
Journal: Experimental cell research 20101115
Title: Concise and enantioselective total synthesis of 15-deoxy-Δ-(12,14)-prostaglandin J(2).
Journal: The Journal of organic chemistry 20101105
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1.
Journal: Biochemical and biophysical research communications 20100903
Title: Modulation of mammary cancer cell migration by 15-deoxy-delta(12,14)-prostaglandin J(2): implications for anti-metastatic therapy.
Journal: The Biochemical journal 20100815
Title: Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Journal: Journal of medicinal chemistry 20100722
Title: 15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells.
Journal: Shock (Augusta, Ga.) 20100701
Title: N-acetylcysteine and 15 deoxy-{delta}12,14-prostaglandin J2 exert a protective effect against autoimmune thyroid destruction in vivo but not against interleukin-1{alpha}/interferon {gamma}-induced inhibitory effects in thyrocytes in vitro.
Journal: The American journal of pathology 20100701
Title: Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma.
Journal: Clinical and experimental immunology 20100601
Title: 15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue.
Journal: Oncogene 20100429
Title: Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2.
Journal: Biochemical and biophysical research communications 20100423
Title: The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2.
Journal: Cancer research 20100415
Title: HtrA3 is regulated by 15-deoxy-Delta12,14-prostaglandin J2 independently of PPARgamma in clear cell renal cell carcinomas.
Journal: Biochemical and biophysical research communications 20100409
Title: Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization.
Journal: Analytical biochemistry 20100401
Title: Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2).
Journal: Experimental neurology 20100401
Title: 15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state.
Journal: Molecular pharmacology 20100401
Title: PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway.
Journal: Cellular signalling 20100301
Title: 15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100301
Title: 15-Deoxy-delta 12-14-prostaglandin-J2 induces hypertrophy and loss of contractility in human testicular peritubular cells: implications for human male fertility.
Journal: Endocrinology 20100301
Title: Aspirin inhibits MMP-9 mRNA expression and release via the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways in macrophages derived from THP-1 cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100201
Title: 15-Deoxy-Delta12,14-prostaglandin J2 inhibits angiotensin II-induced fibronectin expression via hepatocyte growth factor induction in human peritoneal mesothelial cells.
Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20100201
Title: The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells.
Journal: International journal of oncology 20100101
Title: PPARgamma ligand 15-deoxy-delta 12,14-prostaglandin J2 sensitizes human colon carcinoma cells to TWEAK-induced apoptosis.
Journal: Anticancer research 20100101
Title: Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
Journal: American journal of respiratory cell and molecular biology 20091201
Title: Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism.
Journal: Endocrinology 20091201
Title: 15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest.
Journal: Biochemical pharmacology 20091115
Title: Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.
Journal: Journal of medicinal chemistry 20091008
Title: Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport.
Journal: Free radical biology & medicine 20090915
Title: Peroxisome proliferator-activated receptor-gamma ligands 15-deoxy-delta(12,14)-prostaglandin J2 and pioglitazone inhibit hydroxyl peroxide-induced TNF-alpha and lipopolysaccharide-induced CXC chemokine expression in neonatal rat cardiac myocytes.
Journal: Shock (Augusta, Ga.) 20090901
Title: Methods for imaging and detecting modification of proteins by reactive lipid species.
Journal: Free radical biology & medicine 20090801
Title: Effects of 15-deoxy-delta 12, 14-prostaglandin J2 on the expression of p53 in MCF-7 cells.
Journal: Annals of the New York Academy of Sciences 20090801
Title: 15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells.
Journal: Journal of neuropathology and experimental neurology 20090701
Title: 15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells.
Journal: Toxicology letters 20090522
Title: Elevated concentrations of 15-deoxy-Delta12,14-prostaglandin J2 in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor gamma-inducing drugs.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20090501
Title: Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells.
Journal: International journal of oncology 20090501
Title: 15-Deoxy-Delta(12,14)-prostaglandin J(2) induces mitochondrial-dependent apoptosis through inhibition of PKA/NF-kappaB in renal proximal epithelial cells.
Journal: Toxicology 20090405
Title: Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen.
Journal: Neurochemical research 20090401
Title: 15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS.
Journal: Carcinogenesis 20090401
Title: Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor.
Journal: Digestive diseases and sciences 20090201
Title: The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse.
Journal: Endocrinology 20090201
Title: Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2.
Journal: Leukemia 20090201
Title: Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.
Journal: Journal of molecular biology 20090109
Title: 15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292).
Journal: International archives of allergy and immunology 20090101
Title: Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells.
Journal: PloS one 20090101
Title: Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia.
Journal: PloS one 20090101
Title: The 15-deoxy-delta 12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFN-gamma-stimulated astrocytes through induction of MAPK phosphatase-1.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20081215
Title: 15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081201
Title: The role of 15-deoxy-delta(12,14)-prostaglandin J(2), an endogenous ligand of peroxisome proliferator-activated receptor gamma, in tumor angiogenesis.
Journal: Biochemical pharmacology 20081201
Title: 15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2.
Journal: Biochemical pharmacology 20081201
Title: 7beta-hydroxy-epiandrosterone modulation of 15-deoxy-delta12,14-prostaglandin J2, prostaglandin D2 and prostaglandin E2 production from human mononuclear cells.
Journal: The Journal of steroid biochemistry and molecular biology 20081201
Title: Ajulemic acid, a synthetic cannabinoid acid, induces an antiinflammatory profile of eicosanoids in human synovial cells.
Journal: Life sciences 20081107
Title: 15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation.
Journal: Journal of cellular physiology 20081101
Title: Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major.
Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20081101
Title: On the mechanism of inhibition of p27 degradation by 15-deoxy-Delta12,14-prostaglandin J2 in lymphoblasts of Alzheimer's disease patients.
Journal: Cellular and molecular life sciences : CMLS 20081101
Title: 15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53.
Journal: The Journal of biological chemistry 20081031
Title: Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma.
Journal: Bioorganic & medicinal chemistry letters 20081015
Title: The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system.
Journal: Hepatology (Baltimore, Md.) 20081001
Title: 15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase.
Journal: The Journal of biological chemistry 20080905
Title: 15-deoxy-Delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of toll-like receptors 4 and 9 in autoimmune T lymphocyte.
Journal: Journal of clinical immunology 20080901
Title: Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol.
Journal: Toxicology and applied pharmacology 20080815
Title: A natural PPAR-gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080801
Title: Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury.
Journal: Shock (Augusta, Ga.) 20080801
Title: Enhancement of axonal regeneration by in vitro conditioning and its inhibition by cyclopentenone prostaglandins.
Journal: Journal of cell science 20080801
Title: 15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis via JNK-mediated mitochondrial pathway in osteoblastic cells.
Journal: Toxicology 20080627
Title: PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo.
Journal: Investigational new drugs 20080601
Title: Upregulation of lipopolysaccharide-induced interleukin-10 by prostaglandin A1 in mouse peritoneal macrophages.
Journal: Journal of microbiology and biotechnology 20080601
Title: 15-Deoxy-delta12,14-prostaglandin-J(2) up-regulates cyclooxygenase-2 but inhibits prostaglandin-E(2) production through a thiol antioxidant-sensitive mechanism.
Journal: Pharmacological research 20080501
Title: 15-Deoxy-Delta12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS.
Journal: Carcinogenesis 20080401
Title: Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts.
Journal: British journal of pharmacology 20080401
Title: Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages.
Journal: FEBS letters 20080319
Title: BAG-1 inhibits PPARgamma-induced cell death, but not PPARgamma-induced transcription, cell cycle arrest or differentiation in breast cancer cells.
Journal: Oncology reports 20080301
Title: Effects of 15-deoxy-Delta12, 14 prostaglandin J2 and ciglitazone on human cancer cell cycle progression and death: the role of PPARgamma.
Journal: European journal of pharmacology 20080202
Title: Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cells in vitro by blocking NF-kappaB and ERK signalling.
Journal: British journal of pharmacology 20080201
Title: Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages.
Journal: Antioxidants & redox signaling 20080201
Title: 15-Deoxy-Delta12,14-prostaglandin J2 induces chemokine expression, oxidative stress and microfilament reorganization in bovine mammary epithelial cells.
Journal: The Journal of dairy research 20080201
Title: Oxidative stress in the thyroid gland: from harmlessness to hazard depending on the iodine content.
Journal: Endocrinology 20080101
Title: Peroxisome proliferator-activated receptor-gamma agonists attenuate angiotensin II-induced collagen type I expression in adventitial fibroblasts.
Journal: Clinical and experimental pharmacology & physiology 20080101
Title: 15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses.
Journal: Chemical research in toxicology 20080101
Title: Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1.
Journal: Molecular pain 20080101
Title: Peroxisome proliferator-activated receptor gamma is required for the inhibitory effect of ciglitazone but not 15-deoxy-Delta 12,14-prostaglandin J2 on the NFkappaB pathway in human endothelial cells.
Journal: Shock (Augusta, Ga.) 20071201
Title: PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages.
Journal: British journal of pharmacology 20071201
Title: ERK-1/-2 and p38 kinase oppositely regulate 15-deoxy-delta(12,14)-prostaglandinJ(2)-Induced PPAR-gamma activation that mediates dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes.
Journal: Journal of Korean medical science 20071201
Title: Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: role of nuclear factor-kappaB, heat shock factor 1, and Akt.
Journal: Shock (Augusta, Ga.) 20071101
Title: Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes.
Journal: Molecular pharmacology 20071101
Title: Inflammation pro-resolving potential of 3,4-dihydroxyacetophenone through 15-deoxy-delta12,14-prostaglandin J2 in murine macrophages.
Journal: International immunopharmacology 20071101
Title: Accumulation of hypoxia-inducible factor-1alpha through a novel electrophilic, thiol antioxidant-sensitive mechanism.
Journal: Cellular signalling 20071001
Title: Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells.
Journal: Experimental cell research 20071001
Title: 15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways.
Journal: Experimental cell research 20071001
Title: Cyclopentenone prostaglandin, 15-deoxy-Delta12,14-PGJ2, is metabolized by HepG2 cells via conjugation with glutathione.
Journal: Chemical research in toxicology 20071001
Title: 15-deoxy-Delta 12,14-ProstaglandinJ2 regulates dedifferentiation through peroxisome proliferator-activated receptor-gamma-dependent pathway but not COX-2 expression in articular chondrocytes.
Journal: Journal of Korean medical science 20071001
Title: Apoptotic action of peroxisome proliferator-activated receptor-gamma activation in human non small-cell lung cancer is mediated via proline oxidase-induced reactive oxygen species formation.
Journal: Molecular pharmacology 20070901
Title: A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Delta 12, 14 prostaglandin J2 production.
Journal: Blood 20070901
Title: Protective effects of 15-deoxy-Delta12,14-prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutathione.
Journal: Journal of neurochemistry 20070901
Title: Activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) by atorvastatin is mediated by 15-deoxy-delta-12,14-PGJ2.
Journal: Prostaglandins & other lipid mediators 20070801
Title: An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070701
Title: The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages.
Journal: The Journal of biological chemistry 20070622
Title: Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Journal: European journal of pharmacology 20070601
Title: 15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression.
Journal: Breast cancer research and treatment 20070501
Title: Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells.
Journal: Immunology 20070501
Title: Expression and potential role of peroxisome proliferator-activated receptor gamma in the placenta of diabetic pregnancy.
Journal: Placenta 20070401
Title: 15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070401
Title: 15-deoxy-Delta12,14-prostaglandin J2 inhibits transcriptional activity of estrogen receptor-alpha via covalent modification of DNA-binding domain.
Journal: Cancer research 20070315
Title: Hepatic ischemia-reperfusion induces renal heme oxygenase-1 via NF-E2-related factor 2 in rats and mice.
Journal: Molecular pharmacology 20070301
Title: Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival.
Journal: Archives of biochemistry and biophysics 20070115
Title: Up-regulation of skeletal muscle LIM protein 1 gene by 25-hydroxycholesterol may mediate morphological changes of rat aortic smooth muscle cells.
Journal: Life sciences 20070109
Title: Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages.
Journal: Immunology and cell biology 20070101
Title: Peroxisome proliferated-activated receptor gamma ligand, Pioglitazone, does not prevent hepatic fibrosis in mice.
Journal: International journal of molecular medicine 20070101
Title: 15-Deoxy-Delta12,14-prostaglandin J2 enhances docetaxel anti-tumor activity against A549 and H460 non-small-cell lung cancer cell lines and xenograft tumors.
Journal: Anti-cancer drugs 20070101
Title: Anti- and proinflammatory effects of 15-deoxy-delta-prostaglandin J2(15d-PGJ2) on human eosinophil functions.
Journal: International archives of allergy and immunology 20070101
Title: Upregulation of VEGF by 15-deoxy-Delta12,14-prostaglandin J2 via heme oxygenase-1 and ERK1/2 signaling in MCF-7 cells.
Journal: Annals of the New York Academy of Sciences 20061201
Title: 15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors.
Journal: Biochemical pharmacology 20061130
Title: Polymer-assisted solution-phase synthesis and neurite-outgrowth-promoting activity of 15-deoxy-delta(12,14)-PGJ2 derivatives.
Journal: Chemistry, an Asian journal 20061120
Title: 15-deoxy-Delta12,14-prostaglandin J2 induces renal epithelial cell death through NF-kappaB-dependent and MAPK-independent mechanism.
Journal: Toxicology and applied pharmacology 20061101
Title: Protection of RPE cells from oxidative injury by 15-deoxy-delta12,14-prostaglandin J2 by augmenting GSH and activating MAPK.
Journal: Investigative ophthalmology & visual science 20061101
Title: Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase.
Journal: The Journal of biological chemistry 20060908
Title: PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2.
Journal: Journal of neuroimmunology 20060901
Title: Cardiomyocytic apoptosis following global cardiac ischemia and reperfusion can be attenuated by peroxisome proliferator-activated receptor alpha but not gamma activators.
Journal: Shock (Augusta, Ga.) 20060901
Title: 15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism.
Journal: Prostaglandins & other lipid mediators 20060901
Title: Rosiglitazone ameliorates cisplatin-induced renal injury in mice.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
Title: Peroxisome proliferator-activated receptor-gamma ligands inhibit proliferation and induce apoptosis in mantle cell lymphoma.
Journal: Anti-cancer drugs 20060801
Title: Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation.
Journal: Molecular pharmacology 20060701
Title: 15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis.
Journal: Molecular cancer therapeutics 20060701
Title: CYP4A11 is repressed by retinoic acid in human liver cells.
Journal: FEBS letters 20060612
Title: Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection.
Journal: Molecular carcinogenesis 20060601
Title: PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression.
Journal: Acta pharmacologica Sinica 20060601
Title: 15-Deoxy-Delta(12,14)-prostaglandin J(2) suppresses IL-6-induced STAT3 phosphorylation via electrophilic reactivity in endothelial cells.
Journal: Life sciences 20060522
Title: Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms.
Journal: The Journal of biological chemistry 20060519
Title: PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells.
Journal: Cancer letters 20060508
Title: 15-deoxy-Delta12,14-prostaglandin J2 inhibits the expression of microsomal prostaglandin E synthase type 2 in colon cancer cells.
Journal: Journal of lipid research 20060501
Title: Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia.
Journal: Intensive care medicine 20060501
Title: [The role of peroxisome proliferator-activated receptor gamma in proliferation of cardiac non myocytes].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060501
Title: Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells.
Journal: Biochemical pharmacology 20060428
Title: Peroxisome proliferator-activated receptors-gamma activator, ciglitazone, inhibits human melanocyte growth through induction of apoptosis.
Journal: Archives of dermatological research 20060401
Title: Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells.
Journal: Development, growth & differentiation 20060401
Title: Activation of peroxisome proliferator-activated receptor-gamma decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system.
Journal: Molecular cancer research : MCR 20060301
Title: Induction of the 72-kilodalton heat shock protein and protection from ultraviolet B-induced cell death in human keratinocytes by repetitive exposure to heat shock or 15-deoxy-delta(12,14)-prostaglandin J2.
Journal: Cell stress & chaperones 20060301
Title: Peroxisome proliferator-activated receptor gamma in human breast carcinoma: a modulator of estrogenic actions.
Journal: Endocrine-related cancer 20060301
Title: Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060201
Title: Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis.
Journal: Carcinogenesis 20060201
Title: Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways.
Journal: Pharmacological research 20060201
Title: 15-deoxy-Delta12,14-prostaglandin J2 attenuates development of cyclophosphamide-induced cystitis in rats.
Journal: Urology 20060201
Title: Inhibition of skin sclerosis by 15deoxy delta12,14-prostaglandin J2 and retrovirally transfected prostaglandin D synthase in a mouse model of bleomycin-induced scleroderma.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20060101
Title: 15-Deoxy-Delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues.
Journal: Placenta 20060101
Title: Effect of peroxisome proliferator activated receptor (PPAR)gamma agonists on prostaglandins cascade in joint cells.
Journal: Biorheology 20060101
Title: Peroxisome proliferator-activated receptor-gamma is expressed by rat peritoneal mesothelial cells: its potential role in peritoneal cavity local defense.
Journal: American journal of nephrology 20060101
Title: 15-Deoxy-delta12,14-prostaglandin J2, a neuroprotectant or a neurotoxicant?
Journal: Toxicology 20051215
Title: Effect of peroxisome proliferator-activated receptor-gamma ligands on the expression of retinoic acid-inducible gene-I in endothelial cells stimulated with lipopolysaccharide.
Journal: Prostaglandins & other lipid mediators 20051201
Title: The role of transcriptional coactivator TRAP220 in myelomonocytic differentiation.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20051201
Title: Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma.
Journal: Biochemical and biophysical research communications 20051118
Title: Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051115
Title: CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses.
Journal: European journal of pharmacology 20051107
Title: Physiological levels of 15-deoxy-Delta12,14-prostaglandin J2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-gamma ligation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20051101
Title: Augmentation of lipogenesis by 15-deoxy-Delta12,14-prostaglandin J2 in hamster sebaceous glands: identification of cytochrome P-450-mediated 15-deoxy-Delta12,14-prostaglandin J2 production.
Journal: The Journal of investigative dermatology 20051101
Title: Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione.
Journal: FEBS letters 20051024
Title: Trialkyltin compounds bind retinoid X receptor to alter human placental endocrine functions.
Journal: Molecular endocrinology (Baltimore, Md.) 20051001
Title: Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells.
Journal: Biology of reproduction 20050901
Title: Peroxisome proliferator-activated receptor-gamma ligands suppress fibronectin gene expression in human lung carcinoma cells: involvement of both CRE and Sp1.
Journal: American journal of physiology. Lung cellular and molecular physiology 20050901
Title: Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPAR(gamma) agonists: evidence for disparate functional effects which are independent of NF-(kappa)B and PPAR(gamma).
Journal: Cellular signalling 20050901
Title: 15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells.
Journal: The FEBS journal 20050901
Title: 15-deoxy-Delta12, 14-prostaglandin J2 activates the expression of p15INK4b gene, a cyclin-dependent kinase inhibitor.
Journal: International journal of oncology 20050801
Title: The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Title: Troglitazone and 15-deoxy-delta(12,14)-prostaglandin J2 inhibit shear-induced coupling factor 6 release in endothelial cells.
Journal: Cardiovascular research 20050701
Title: 15-Deoxy-delta12,14-PGJ2 inhibits IL-6-induced Stat3 phosphorylation in lymphocytes.
Journal: Experimental & molecular medicine 20050630
Title: Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury.
Journal: American journal of respiratory and critical care medicine 20050601
Title: 15-Deoxy-{delta}12,14-prostaglandin j2 inhibits interleukin-1{beta}-induced nuclear factor-{kappa}b in human amnion and myometrial cells: mechanisms and implications.
Journal: The Journal of clinical endocrinology and metabolism 20050601
Title: Upregulation of LPS-induced chemokine KC expression by 15-deoxy-delta12,14-prostaglandin J2 in mouse peritoneal macrophages.
Journal: Immunology and cell biology 20050601
Title: Glycolaldehyde-modified bovine serum albumin downregulates leptin expression in mouse adipocytes via a CD36-mediated pathway.
Journal: Annals of the New York Academy of Sciences 20050601
Title: Selective activation of PPARgamma in breast, colon, and lung cancer cell lines.
Journal: Molecular and cellular endocrinology 20050512
Title: Modeling MODS: what can be learned from animal models of the multiple-organ dysfunction syndrome?
Journal: Intensive care medicine 20050501
Title: The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock.
Journal: Intensive care medicine 20050501
Title: Expression of PPARgamma and beta/delta in human primary osteoblastic cells: influence of polyunsaturated fatty acids.
Journal: Calcified tissue international 20050501
Title: Thiazolidinediones inhibit apoptosis and heat shock protein 60 expression in human vascular endothelial cells.
Journal: Thrombosis and haemostasis 20050501
Title: Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.
Journal: The Journal of biological chemistry 20050408
Title: Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats.
Journal: The Journal of pharmacology and experimental therapeutics 20050401
Title: 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) signals through retinoic acid receptor-related orphan receptor-alpha but not peroxisome proliferator-activated receptor-gamma in human vascular endothelial cells: the effect of 15d-PGJ2 on tumor necrosis factor-alpha-induced gene expression.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050401
Title: Cyclopentenone prostaglandins PGA2 and 15-deoxy-delta12,14 PGJ2 suppress activation of murine microglia and astrocytes: implications for multiple sclerosis.
Journal: Journal of neuroscience research 20050401
Title: Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis.
Journal: Journal of neuroimmunology 20050401
Title: Proteasome inhibitors induce peroxisome proliferator-activated receptor transactivation through RXR accumulation and a protein kinase C-dependent pathway.
Journal: Experimental cell research 20050310
Title: The possible role of heat shock factor-1 in the negative regulation of heme oxygenase-1.
Journal: The international journal of biochemistry & cell biology 20050301
Title: Expression of survivin and bax/bcl-2 in peroxisome proliferator activated receptor-gamma ligands induces apoptosis on human myeloid leukemia cells in vitro.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050301
Title: Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARgamma-independent mechanism.
Journal: Diabetologia 20050301
Title: Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism.
Journal: Arthritis and rheumatism 20050301
Title: 15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins.
Journal: Blood 20050215
Title: Effect of rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 on bleomycin-induced lung injury.
Journal: The European respiratory journal 20050201
Title: Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor gamma for monocyte recruitment and endothelial regeneration.
Journal: European journal of pharmacology 20050131
Title: Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists.
Journal: The Journal of biological chemistry 20050128
Title: Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism.
Journal: Arthritis and rheumatism 20050101
Title: [Role of prostaglandins in rheumatoid arthritis].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050101
Title: 15-Deoxy-Delta12,14-prostaglandin J2 and peroxisome proliferator-activated receptor gamma (PPARgamma) levels in term placental tissues from control and diabetic rats: modulatory effects of a PPARgamma agonist on nitridergic and lipid placental metabolism.
Journal: Reproduction, fertility, and development 20050101
Title: Unusual astrocyte reactivity caused by the food mycotoxin ochratoxin A in aggregating rat brain cell cultures.
Journal: Neuroscience 20050101
Title: Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2.
Journal: Arthritis research & therapy 20050101
Title: A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist.
Journal: Analytical biochemistry 20041215
Title: Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.
Journal: Molecular pharmacology 20041101
Title: Human multiple myeloma cells express peroxisome proliferator-activated receptor gamma and undergo apoptosis upon exposure to PPARgamma ligands.
Journal: Clinical immunology (Orlando, Fla.) 20041101
Title: 15-Deoxy-Delta12,14-prostaglandin J(2) protects against nitrosative PC12 cell death through up-regulation of intracellular glutathione synthesis.
Journal: The Journal of biological chemistry 20041029
Title: Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias.
Journal: Molecular cancer therapeutics 20041001
Title: Induction of reversible cysteine-targeted protein oxidation by an endogenous electrophile 15-deoxy-delta12,14-prostaglandin J2.
Journal: Chemical research in toxicology 20041001
Title: Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro.
Journal: The British journal of dermatology 20041001
Title: 15-deoxy-delta12,14-prostaglandin-J2 inhibits expression of eNOS in human endothelial cells.
Journal: Prostaglandins & other lipid mediators 20041001
Title: Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells.
Journal: Biochemical and biophysical research communications 20040917
Title: A potential role of 15-deoxy-delta(12,14)-prostaglandin J2 for induction of human articular chondrocyte apoptosis in arthritis.
Journal: The Journal of biological chemistry 20040903
Title: Fenofibrate, troglitazone, and 15-deoxy-Delta12,14-prostaglandin J2 close KATP channels and induce insulin secretion.
Journal: The Journal of pharmacology and experimental therapeutics 20040901
Title: Environmental and endogenous peroxisome proliferator-activated receptor gamma agonists induce bone marrow B cell growth arrest and apoptosis: interactions between mono(2-ethylhexyl)phthalate, 9-cis-retinoic acid, and 15-deoxy-Delta12,14-prostaglandin J2.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040901
Title: 15-deoxy-Delta12,14-prostaglandin J2 inhibits IFN-inducible protein 10/CXC chemokine ligand 10 expression in human microglia: mechanisms and implications.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040901
Title: 15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity.
Journal: The Journal of biological chemistry 20040820
Title: Activators of PPARgamma antagonize protection of cardiac myocytes by endothelin-1.
Journal: Biochemical and biophysical research communications 20040820
Title: 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkappaBalpha degradation in rat chondrocytes through a PPARgamma-independent pathway.
Journal: FEBS letters 20040813
Title: The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in Mycosis fungoides/Sézary syndrome cells.
Journal: The Journal of investigative dermatology 20040801
Title: The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines.
Journal: International journal of oncology 20040801
Title: Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism.
Journal: Cancer research 20040801
Title: Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells.
Journal: Cancer letters 20040728
Title: Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway.
Journal: Experimental cell research 20040715
Title: 15-deoxy-Delta12,14-prostaglandin J2 inhibits glucocorticoid binding and signaling in macrophages through a peroxisome proliferator-activated receptor gamma-independent process.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040615
Title: 15-deoxy-delta12,14-prostaglandin J2 inhibits Bay 11-7085-induced sustained extracellular signal-regulated kinase phosphorylation and apoptosis in human articular chondrocytes and synovial fibroblasts.
Journal: The Journal of biological chemistry 20040521
Title: Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.
Journal: The Journal of biological chemistry 20040521
Title: 15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes.
Journal: The Journal of biological chemistry 20040521
Title: Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer.
Journal: Cancer research 20040515
Title: Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.
Journal: American journal of physiology. Endocrinology and metabolism 20040401
Title: Thiol antioxidant and thiol-reducing agents attenuate 15-deoxy-delta 12,14-prostaglandin J2-induced heme oxygenase-1 expression.
Journal: Life sciences 20040326
Title: Expression and function of PPARgamma in rat placental development.
Journal: Biochemical and biophysical research communications 20040305
Title: Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2).
Journal: Biochemistry 20040302
Title: Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products.
Journal: The Biochemical journal 20040301
Title: Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells.
Journal: Gut 20040301
Title: Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin.
Journal: Critical care medicine 20040301
Title: Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism.
Journal: The Journal of biological chemistry 20040227
Title: Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1.
Journal: The Journal of biological chemistry 20040220
Title: The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.
Journal: Cardiovascular research 20040215
Title: 15-deoxy prostaglandin J2 enhances allyl alcohol-induced toxicity in rat hepatocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040201
Title: Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.
Journal: Molecular pharmacology 20040201
Title: 15-Deoxy-delta(12,14)-prostaglandin J2 inhibits the IL-1beta-induced expression of granulocyte-macrophage colony-stimulating factor in BEAS-2B bronchial epithelial cells.
Journal: The Tohoku journal of experimental medicine 20040201
Title: Antiinflammatory roles of peroxisome proliferator-activated receptor gamma in human alveolar macrophages.
Journal: American journal of respiratory and critical care medicine 20040115
Title: Effect of nuclear factor-kappa B inhibitors and peroxisome proliferator-activated receptor-gamma ligands on PTHrP release from human fetal membranes.
Journal: Placenta 20040101
Title: 15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide.
Journal: The Journal of biological chemistry 20031226
Title: Expression of the murine glutathione S-transferase alpha3 (GSTA3) subunit is markedly induced during adipocyte differentiation: activation of the GSTA3 gene promoter by the pro-adipogenic eicosanoid 15-deoxy-Delta12,14-prostaglandin J2.
Journal: Biochemical and biophysical research communications 20031226
Title: Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2.
Journal: The Journal of biological chemistry 20031219
Title: Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20031215
Title: An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome.
Journal: Biochemistry 20031202
Title: Oxidized low-density lipoprotein and 15-deoxy-delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells.
Journal: American journal of physiology. Heart and circulatory physiology 20031201
Title: The effect of peroxisome proliferator-activated receptor-gamma ligand on urological cancer cells.
Journal: International journal of molecular medicine 20031201
Title: 15-Deoxy-delta12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-gamma, induces apoptosis in human hepatoma cells.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20031201
Title: 15-Deoxy-Delta(12,14)-prostaglandin J2 induces apoptosis through activation of the CHOP gene in HeLa cells.
Journal: Biochemical and biophysical research communications 20031107
Title: Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway.
Journal: The Journal of pharmacology and experimental therapeutics 20031101
Title: 15-deoxy-delta12,14-prostaglandin J2 regulates the functional state and the survival of microglial cells through multiple molecular mechanisms.
Journal: Journal of neurochemistry 20031101
Title: Effect of 15-deoxy-delta12,14-prostaglandin J2 on IL-1beta-induced expression of epithelial neutrophil-activating protein-78 in human endothelial cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20031101
Title: Peroxisome proliferator-activated receptor gamma ligands attenuate immunological symptoms of experimental allergic asthma.
Journal: Archives of biochemistry and biophysics 20031015
Title: Apoptosis in human oral squamous cell carcinomas is induced by 15-deoxy-delta 12,14-prostaglandin J2 but not by troglitazone.
Journal: Journal of dental research 20031001
Title: 15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma.
Journal: Laboratory investigation; a journal of technical methods and pathology 20031001
Title: Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma.
Journal: The Journal of clinical investigation 20030915
Title: Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.
Journal: British journal of pharmacology 20030901
Title: Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2.
Journal: Experimental & molecular medicine 20030831
Title: The PPAR-gamma ligand 15-deoxy(delta12,14) prostaglandin J2 reduces the liver injury in endotoxic shock.
Journal: European journal of pharmacology 20030829
Title: Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect.
Journal: The Journal of biological chemistry 20030815
Title: Expression and molecular pharmacology of the mouse CRTH2 receptor.
Journal: The Journal of pharmacology and experimental therapeutics 20030801
Title: Human invasive trophoblasts transformed with simian virus 40 provide a new tool to study the role of PPARgamma in cell invasion process.
Journal: Carcinogenesis 20030801
Title: Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element.
Journal: Fertility and sterility 20030801
Title: Structural requirements of cyclopentenone prostaglandins to induce endothelial cell apoptosis.
Journal: Biochemical and biophysical research communications 20030725
Title: Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030715
Title: Thioredoxin as a molecular target of cyclopentenone prostaglandins.
Journal: The Journal of biological chemistry 20030711
Title: Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells.
Journal: European journal of pharmacology 20030704
Title: 15-deoxy-delta 12,14-prostaglandin J2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells.
Journal: American journal of physiology. Heart and circulatory physiology 20030701
Title: Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli.
Journal: Shock (Augusta, Ga.) 20030701
Title: Anti-inflammatory activity of 15-deoxy-delta12,14-PGJ2 and 2-cyclopenten-1-one: role of the heat shock response.
Journal: Molecular pharmacology 20030701
Title: Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells.
Journal: Investigative ophthalmology & visual science 20030701
Title: Regulation of retinoic acid receptor beta expression by peroxisome proliferator-activated receptor gamma ligands in cancer cells.
Journal: Cancer research 20030701
Title: 15-Deoxy-delta 12,14-prostaglandin J2 inhibits the expression of granulocyte-macrophage colony-stimulating factor in endothelial cells stimulated with lipopolysaccharide.
Journal: Prostaglandins & other lipid mediators 20030701
Title: Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.
Journal: Oncogene 20030619
Title: Effects of peroxisome proliferator-activated receptor gamma ligands ciglitazone and 15-deoxy-delta 12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability.
Journal: Journal of neuroscience research 20030615
Title: Activation of nuclear receptors by prostaglandins.
Journal: Thrombosis research 20030615
Title: Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells.
Journal: The Journal of pharmacology and experimental therapeutics 20030601
Title: Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030601
Title: 15-deoxy-delta12,14 prostaglandin J2 synergizes with phorbol ester to induce proliferation in Swiss 3T3 cells independently of peroxisome proliferator-activated receptor gamma and PGD2 receptors.
Journal: Journal of cellular physiology 20030601
Title: Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2.
Journal: The Journal of biological chemistry 20030523
Title: Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells.
Journal: Biochemistry 20030513
Title: The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030501
Title: Activation-induced PPARgamma expression sensitizes primary human T cells toward apoptosis.
Journal: Journal of leukocyte biology 20030501
Title: Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells.
Journal: Molecular carcinogenesis 20030501
Title: 15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia.
Journal: The Journal of biological chemistry 20030425
Title: DR1-like element in human topoisomerase IIalpha gene involved in enhancement of etoposide-induced apoptosis by PPARgamma ligand.
Journal: Experimental hematology 20030401
Title: Possible involvement of small oligomers of amyloid-beta peptides in 15-deoxy-delta 12,14 prostaglandin J2-sensitive microglial activation.
Journal: Journal of pharmacological sciences 20030401
Title: Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma.
Journal: Cancer research 20030315
Title: 15-Deoxy-Delta(12,14)-prostaglandin J2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism.
Journal: Biochemical and biophysical research communications 20030307
Title: Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030301
Title: Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-delta12,14-prostaglandin J2.
Journal: Molecular pharmacology 20030301
Title: GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030301
Title: Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells.
Journal: Fertility and sterility 20030301
Title: Prostaglandin J2 metabolites inhibit aromatase activity by redox-sensitive mechanisms: potential implications for breast cancer therapy.
Journal: International journal of cancer 20030220
Title: The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat.
Journal: British journal of pharmacology 20030201
Title: Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030115
Title: Expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma and levels of prostaglandin E2 and 15-deoxy-delta12,14-prostaglandin J2 in human breast cancer and metastasis.
Journal: International journal of cancer 20030101
Title: Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20030101
Title: Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells.
Journal: Placenta 20030101
Title: Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2.
Journal: BMC ophthalmology 20030101
Title: 15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells.
Journal: British journal of cancer 20021202
Title: 15-Deoxy-D12,14-prostaglandin J2 inhibits CX3CL1/fractalkine expression in human endothelial cells.
Journal: Immunology and cell biology 20021201
Title: Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021201
Title: 15-Deoxy-delta12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells.
Journal: Journal of lipid research 20021101
Title: Modulation of nitric oxide concentration and lipid metabolism by 15-deoxy Delta12,14prostaglandin J2 in embryos from control and diabetic rats during early organogenesis.
Journal: Reproduction (Cambridge, England) 20021101
Title: 15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes.
Journal: Osteoarthritis and cartilage 20021101
Title: 15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma.
Journal: Biochemical and biophysical research communications 20021018
Title: Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone.
Journal: The Journal of clinical endocrinology and metabolism 20021001
Title: Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli.
Journal: Experimental hematology 20020901
Title: Agonists of peroxisome proliferator-activated receptor gamma inhibit cell growth in malignant melanoma.
Journal: The Journal of investigative dermatology 20020901
Title: 15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade.
Journal: Thrombosis and haemostasis 20020901
Title: Translational regulation of cyclin D1 by 15-deoxy-delta(12,14)-prostaglandin J(2).
Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020901
Title: MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species.
Journal: The Journal of biological chemistry 20020816
Title: 15-Deoxy-delta12,14-prostaglandin J2 induces apoptosis of a thyroid papillary cancer cell line (CG3 cells) through increasing intracellular iron and oxidative stress.
Journal: Anti-cancer drugs 20020801
Title: Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929.
Journal: Experimental cell research 20020715
Title: Inhibitory effect of peroxisome proliferator-activated receptor-gamma ligands on the expression of IgE heavy chain germline transcripts in the human B cell line DND39.
Journal: Biochemical and biophysical research communications 20020712
Title: Natural ligands of PPARgamma: are prostaglandin J(2) derivatives really playing the part?
Journal: Cellular signalling 20020701
Title: Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20020701
Title: Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020701
Title: Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2.
Journal: Brain research 20020621
Title: Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020615
Title: Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation.
Journal: Endocrinology 20020601
Title: 15-Deoxy-Delta12,14-prostaglandin J2 inhibits IL-1beta-induced cyclooxygenase-2 expression in mesangial cells.
Journal: Kidney international 20020601
Title: A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020515
Title: Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells.
Journal: Gut 20020501
Title: Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020501
Title: The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation.
Journal: Molecular pharmacology 20020501
Title: Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Delta(12,14)(12,14)-prostaglandin J(2) in activated human astrocytes, but not in human brain macrophages.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020501
Title: Peroxisome-proliferator-activated-receptor gamma (PPARgamma) independent induction of CD36 in THP-1 monocytes by retinoic acid.
Journal: Immunology 20020501
Title: Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer.
Journal: Life sciences 20020419
Title: Conjugated linoleic acid decreases production of pro-inflammatory products in macrophages: evidence for a PPAR gamma-dependent mechanism.
Journal: Biochimica et biophysica acta 20020415
Title: 15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020401
Title: 15-Deoxy-Delta12,14-prostaglandin J2 regulates mesangial cell proliferation and death.
Journal: Kidney international 20020401
Title: Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation.
Journal: Genes and immunity 20020401
Title: Effect of PPARgamma ligands on the viability of gastric epithelial cells.
Journal: Alimentary pharmacology & therapeutics 20020401
Title: Activation of the mouse heme oxygenase-1 gene by 15-deoxy-Delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2.
Journal: Antioxidants & redox signaling 20020401
Title: Inhibition of inducible prostaglandin E(2) synthase by 15-deoxy-Delta(12,14)-prostaglandin J(2) and polyunsaturated fatty acids.
Journal: Biochemical pharmacology 20020315
Title: Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells.
Journal: Pancreas 20020301
Title: Prostaglandins as modulators of immunity.
Journal: Trends in immunology 20020301
Title: Streptozotocin-pancreatic damage in the rat: modulatory effect of 15-deoxy delta12,14-prostaglandin j(2) on nitridergic and prostanoid pathway.
Journal: Nitric oxide : biology and chemistry 20020301
Title: 15 deoxy delta12,14 PGJ2 induces procoagulant activity in cultured human endothelial cells.
Journal: Thrombosis and haemostasis 20020301
Title: 15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020201
Title: Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020201
Title: Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism.
Journal: Arthritis and rheumatism 20020201
Title: Ligands of peroxisome proliferator-activated receptor-gamma block activation of pancreatic stellate cells.
Journal: The Journal of biological chemistry 20020104
Title: Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells.
Journal: Biology of reproduction 20020101
Title: Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20020101
Title: Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages.
Journal: Atherosclerosis 20020101
Title: Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells.
Journal: Immunology 20020101
Title: Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells.
Journal: International journal of gastrointestinal cancer 20020101
Title: 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells.
Journal: The Journal of biological chemistry 20011228
Title: Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells.
Journal: The Journal of biological chemistry 20011214
Title: Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature.
Journal: American journal of physiology. Renal physiology 20011201
Title: 15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells.
Journal: Prostaglandins & other lipid mediators 20011201
Title: Lipid peroxidation end products-responded induction of a preneoplastic marker enzyme glutathione S-transferase P-form (GST-P) in rat liver on admistration via the portal vein.
Journal: Mutation research 20011101
Title: Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20011101
Title: 15-Deoxy-delta(12,14)-prostaglandin J2 is a negative regulator of macrophage functions.
Journal: International immunopharmacology 20011101
Title: The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells.
Journal: Journal of cell science 20011101
Title: Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: a peroxisome proliferator-activated receptor-gamma (PPARgamma)-independent, antioxidant-related mechanism.
Journal: Biochemical pharmacology 20011015
Title: Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma -dependent and -independent pathways.
Journal: The Journal of biological chemistry 20011012
Title: 15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors.
Journal: The Journal of biological chemistry 20011012
Title: Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes.
Journal: Circulation 20011002
Title: Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20011001
Title: Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20011001
Title: Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists.
Journal: Biochemical and biophysical research communications 20010928
Title: 15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit.
Journal: The Journal of biological chemistry 20010921
Title: PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity.
Journal: International journal of oncology 20010901
Title: Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20010901
Title: PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells.
Journal: Biochemical and biophysical research communications 20010824
Title: Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells.
Journal: Journal of the American Society of Nephrology : JASN 20010801
Title: Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells.
Journal: The American journal of pathology 20010801
Title: 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways.
Journal: FEBS letters 20010713
Title: Peroxisome proliferator-activated receptor gamma-mediated transcriptional up-regulation of the hepatocyte growth factor gene promoter via a novel composite cis-acting element.
Journal: The Journal of biological chemistry 20010706
Title: Differential regulation of chemokine gene expression by 15-deoxy-delta 12,14 prostaglandin J2.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010615
Title: Peroxisome proliferator-activated receptor gamma-retinoid X receptor agonists increase CD36-dependent phagocytosis of Plasmodium falciparum-parasitized erythrocytes and decrease malaria-induced TNF-alpha secretion by monocytes/macrophages.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010601
Title: Peroxisome proliferator-activated receptor-gamma regulates airway epithelial cell activation.
Journal: American journal of respiratory cell and molecular biology 20010601
Title: Adipophilin is a sensitive marker for lipid loading in human blood monocytes.
Journal: Biochimica et biophysica acta 20010531
Title: Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2.
Journal: Biochemical and biophysical research communications 20010518
Title: 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-10 and IL-12 production by macrophages.
Journal: Biochemical and biophysical research communications 20010504
Title: Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines.
Journal: Endocrinology 20010501
Title: Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300.
Journal: The Journal of biological chemistry 20010413
Title: Dual function of troglitazone in ICAM-1 gene expression in human vascular endothelium.
Journal: Biochemical and biophysical research communications 20010406
Title: The cyclopentone prostaglandin 15-deoxy-Delta(12,14) prostaglandin J2 represses nitric oxide, TNF-alpha, and IL-12 production by microglial cells.
Journal: Journal of neuroimmunology 20010402
Title: The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis.
Journal: European journal of immunology 20010401
Title: Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Journal: Journal of leukocyte biology 20010401
Title: A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma.
Journal: Biochemical and biophysical research communications 20010216
Title: Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010215
Title: Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12-14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo.
Journal: Endocrinology 20010201
Title: 15-Deoxy-Delta(12,14)-prostaglandin J(2) facilitates thyroglobulin production by cultured human thyrocytes.
Journal: American journal of physiology. Cell physiology 20001201
Title: Regulation of leptin release by troglitazone in human adipose tissue.
Journal: Metabolism: clinical and experimental 20001101
Title: Bisphenol A diglycidyl ether (BADGE) is a PPARgamma agonist in an ECV304 cell line.
Journal: British journal of pharmacology 20001001
Title: Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways.
Journal: The Journal of biological chemistry 20000908
Title: PPAR-gamma is selectively upregulated in Caco-2 cells by butyrate.
Journal: Biochemical and biophysical research communications 20000607
Title: Troglitazone inhibits mitogenic signaling by insulin in vascular smooth muscle cells.
Journal: Journal of cardiovascular pharmacology 20000501
Title: Expression of peroxisomal proliferator-activated receptors and retinoid X receptors in the kidney.
Journal: The American journal of physiology 19991201
Title: Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo.
Journal: The Journal of biological chemistry 19990326
Title: Thiazolidinediones suppress endothelin-1 secretion from bovine vascular endothelial cells: a new possible role of PPARgamma on vascular endothelial function.
Journal: Biochemical and biophysical research communications 19990127
Title: Troglitazone induces expression of PPARgamma in liver.
Journal: Molecular cell biology research communications : MCBRC 19990101
Title: Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.
Journal: British journal of pharmacology 19980401
Title: Development of a scintillation proximity assay for peroxisome proliferator-activated receptor gamma ligand binding domain.
Journal: Analytical biochemistry 19980315
Title: Glucocorticoids repress induction by thiazolidinediones, fibrates, and fatty acids of phosphoenolpyruvate carboxykinase gene expression in adipocytes.
Journal: Journal of cellular biochemistry 19980301
Title: Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells.
Journal: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 19980301
Title: Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19970429
Title: Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs.
Journal: The Journal of biological chemistry 19970207
Title: Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19970121
Title: A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.
Journal: Cell 19951201
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