[1]BiologicalandPharmaceuticalBulletin,2001,vol.24,p.1113-1116
[1]BiologicalandPharmaceuticalBulletin,2001,vol.24,p.1113-1116
[1]CurrentPatentAssignee:CHONGQINGSHENGHUAXIPHARMACEUTICALSCOLTD-CN112174966,2021,ALocationinpatent:Paragraph0006;0011;0014;0015;0016;0019;0020
[1]CurrentPatentAssignee:CHONGQINGSHENGHUAXIPHARMACEUTICALSCOLTD-CN112174966,2021,A
Title: A Case of Sudden Cardiac Death due to Pilsicainide-Induced Torsades de Pointes.
Journal: Korean circulation journal 20140301
Title: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201
Title: Rate-dependent and site-specific conduction block at the posterior right atrium and drug effects evaluated using a noncontact mapping system in patients with typical atrial flutter.
Journal: Journal of cardiovascular electrophysiology 20120801
Title: Electrophysiological effects of the class Ic antiarrhythmic drug pilsicainide on the guinea-pig pulmonary vein myocardium.
Journal: Journal of pharmacological sciences 20120101
Title: Pharmacologic atrial defibrillation by drug delivery into the temporarily occluded coronary sinus. A canine study.
Journal: International heart journal 20120101
Title: A sodium channel blocker, pilsicainide, produces atrial post-repolarization refractoriness through the reduction of sodium channel availability.
Journal: The Tohoku journal of experimental medicine 20110901
Title: A new criteria differentiating type 2 and 3 Brugada patterns from ordinary incomplete right bundle branch block.
Journal: International heart journal 20110101
Title: Right ventricular dysfunction in patients with Brugada-like electrocardiography: a two dimensional strain imaging study.
Journal: Cardiovascular ultrasound 20110101
Title: [Two elderly case reports of renal excretion type drug poisoning caused by dehydration that was due to poor eating in home care].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20101201
Title: Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline.
Journal: The American journal of cardiology 20101101
Title: Ischemia-induced Brugada-type ST-segment alternans and Brugada syndrome.
Journal: International journal of cardiology 20101029
Title: What variables were associated with the inducibility of ventricular fibrillation during electrophysiologic stimulation test in patients without apparent organic heart disease?
Journal: Journal of cardiology 20100701
Title: Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Journal: British journal of pharmacology 20100701
Title: Conduction delay in right ventricle as a marker for identifying high-risk patients with Brugada syndrome.
Journal: Journal of cardiovascular electrophysiology 20100601
Title: Genotype-phenotype correlation in tissue models of Brugada syndrome simulating patients with sodium and calcium channelopathies.
Journal: Heart rhythm 20100601
Title: Ventricular fibrillation diagnosed during electrophysiological study for non-sustained tachycardia.
Journal: Aviation, space, and environmental medicine 20100601
Title: Pilsicainide.
Journal: Drugs 20100305
Title: Ventricular late potential in patients with apparently normal electrocardiogram; predictor of Brugada syndrome.
Journal: Pacing and clinical electrophysiology : PACE 20100301
Title: A novel microsatellite polymorphism of sodium channel beta1-subunit gene (SCN1B) may underlie abnormal cardiac excitation manifested by coved-type ST-elevation compatible with Brugada syndrome in Japanese.
Journal: International journal of clinical pharmacology and therapeutics 20100201
Title: A predictor of positive drug provocation testing in individuals with saddle-back type ST-segment elevation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091001
Title: Predicting the efficacy of antiarrhythmic agents for interrupting persistent atrial fibrillation according to spectral analysis of the fibrillation waves on the surface ECG.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090701
Title: Simultaneous assessment of pharmacokinetics of pilsicainide transdermal patch and its electropharmacological effects on atria of chronic atrioventricular block dogs.
Journal: Journal of pharmacological sciences 20090701
Title: Pilsicainide-induced ST segment elevation and ST segment depression in two patients with variant forms of Brugada-type electrocardiographic abnormalities.
Journal: Pacing and clinical electrophysiology : PACE 20090601
Title: Early termination of spiral wave reentry by combined blockade of Na+ and L-type Ca2+ currents in a perfused two-dimensional epicardial layer of rabbit ventricular myocardium.
Journal: Heart rhythm 20090501
Title: Mapping ventricular fibrillation: a simplified experimental model leads to a complicated result.
Journal: Heart rhythm 20090501
Title: Effect of pilsicainide on dominant frequency in the right and left atria and pulmonary veins during atrial fibrillation: association with its atrial fibrillation terminating effect.
Journal: European journal of pharmacology 20090417
Title: Action potential alternans in the right ventricular outflow tract in a patient with asymptomatic Brugada syndrome.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090301
Title: An open-label, single-dose, parallel-group, dose-increasing study comparing the pharmacokinetics and tolerability of pilsicainide hydrochloride in healthy Korean and Japanese male subjects.
Journal: Clinical therapeutics 20090301
Title: A randomized study on the efficacy of intravenous cibenzoline and pilsicainide administered prior to electrical cardioversion in patients with lone paroxysmal and persistent atrial fibrillation.
Journal: Journal of cardiology 20090201
Title: Pilsicainide intoxication presenting as left ventricular dyssynchrony in a patient on hemodialysis.
Journal: Journal of cardiology 20090201
Title: Acute fatal poisoning with pilsicainide and atenolol.
Journal: International journal of legal medicine 20081101
Title: Menstruation-dependent idiopathic ventricular arrhythmia.
Journal: Gender medicine 20080601
Title: Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080501
Title: Re: Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
Journal: Journal of cardiovascular electrophysiology 20080401
Title: Longer repolarization in the epicardium at the right ventricular outflow tract causes type 1 electrocardiogram in patients with Brugada syndrome.
Journal: Journal of the American College of Cardiology 20080325
Title: Clinical and electrophysiological characteristics of patients having atrial flutter with 1:1 atrioventricular conduction.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080301
Title: Clinical significance of macroscopic T-wave alternans after sodium channel blocker administration in patients with Brugada syndrome.
Journal: Journal of cardiovascular electrophysiology 20080101
Title: Pilsicainide-induced Brugada-type ECG and ventricular arrhythmias originating from the left posterior fascicle in a case with Brugada syndrome associated with idiopathic left ventricular tachycardia.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080101
Title: Sodium channel blockers enhance the temporal QT interval variability in the right precordial leads in Brugada syndrome.
Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20080101
Title: Mechanisms of the preventive effect of pilsicainide on atrial fibrillation originating from the pulmonary vein.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20071101
Title: [Elderly Brugada syndrome with recurrent syncope, diagnosed by pilsicainide challenge test].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070610
Title: Pilsicainide-induced ventricular tachycardia originating from right ventricular outflow tract.
Journal: Journal of cardiovascular electrophysiology 20070501
Title: Incidence and initial characteristics of pilsicainide-induced ventricular arrhythmias in patients with Brugada syndrome.
Journal: Pacing and clinical electrophysiology : PACE 20070501
Title: Discrimination of Brugada syndrome patients from individuals with the saddle-back type ST-segment elevation using a marker of the standard 12-lead electrocardiography.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070401
Title: Temperature modulation of ventricular arrhythmogenicity in a canine tissue model of Brugada syndrome.
Journal: Heart rhythm 20070201
Title: How can a single mutation cause such arrhythmic havoc?
Journal: Heart rhythm 20070201
Title: Different effect of the pure Na+ channel-blocker pilsicainide on the ST-segment response in the right precordial leads in patients with normal left ventricular function.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070101
Title: High-frequency potentials developed in wavelet-transformed electrocardiogram as a novel indicator for detecting Brugada syndrome.
Journal: Heart rhythm 20061201
Title: Comment on severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency.
Journal: Clinical pharmacology and therapeutics 20061201
Title: Multiple premature beats triggered ventricular arrhythmias during pilsicainide infusion in a patient with inferior ST-segment elevation.
Journal: Pacing and clinical electrophysiology : PACE 20061201
Title: Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation.
Journal: Pacing and clinical electrophysiology : PACE 20060901
Title: Effects of antiarrhythmic drugs on apoptotic pathways in H9c2 cardiac cells.
Journal: Journal of pharmacological sciences 20060801
Title: Pharmacological conversion of persistent atrial fibrillation into sinus rhythm with oral pilsicainide: pilsicainide suppression trial for persistent atrial fibrillation II.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20060601
Title: Randomized crossover study of the long-term effects of pilsicainide and cibenzoline in preventing recurrence of symptomatic paroxysmal atrial fibrillation: influence of the duration of arrhythmia before therapy.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20060601
Title: The full stomach test as a novel diagnostic technique for identifying patients at risk of Brugada syndrome.
Journal: Journal of cardiovascular electrophysiology 20060601
Title: Cellular basis for trigger and maintenance of ventricular fibrillation in the Brugada syndrome model: high-resolution optical mapping study.
Journal: Journal of the American College of Cardiology 20060516
Title: Pilsicainide-induced verapamil sensitive idiopathic left ventricular tachycardia.
Journal: Pacing and clinical electrophysiology : PACE 20060501
Title: Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2.
Journal: Clinical pharmacology and therapeutics 20060401
Title: Population pharmacokinetic and pharmacodynamic analysis of a class IC antiarrhythmic, pilsicainide, in patients with cardiac arrhythmias.
Journal: Journal of clinical pharmacology 20060101
Title: [Case in which magnesium sulfate effectively treated ventricular tachycardia due to overdose of pilsicainide hydrochloride].
Journal: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20060101
Title: Pilsicainide for atrial fibrillation.
Journal: Drugs 20060101
Title: Hybrid therapy with pilsicainide and pulmonary vein isolation for atrial fibrillation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20051201
Title: Heart rate variability is a useful parameter for evaluation of anticholinergic effect associated with inducibility of atrial fibrillation.
Journal: Pacing and clinical electrophysiology : PACE 20051101
Title: A simple in vivo atrial fibrillation model of rat induced by transesophageal atrial burst pacing.
Journal: Journal of pharmacological sciences 20050701
Title: Pilsicainide-induced coronary vasospasm in a patient with Brugada-type electrocardiogram.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20050701
Title: Effect of sodium channel blocker, pilsicainide hydrochloride, on net inward current of atrial myocytes in thyroid hormone toxicosis rats.
Journal: Thyroid : official journal of the American Thyroid Association 20050701
Title: Long-term efficacy of hybrid pharmacologic and ablation therapy in patients with pilsicainide-induced atrial flutter.
Journal: Clinical cardiology 20050701
Title: Effect of protein binding of pilsicainide on the pharmacokinetics.
Journal: Drug metabolism and pharmacokinetics 20050601
Title: Pilsicainide in breast milk from a mother: comparison with disopyramide and propafenone.
Journal: British journal of clinical pharmacology 20050101
Title: Three elderly cases with Brugada-type electrocardiographic pattern unmasked by pilsicainide at the toxic level.
Journal: Internal medicine (Tokyo, Japan) 20050101
Title: Mexiletine protects myocardium during acute ischemia by opening sarcolemmal K-ATP channel: studies in closed-chest acute ischemia model in rabbits.
Journal: Journal of cardiovascular pharmacology 20041201
Title: Effects of the NA+ channel blocker pilsicainide on the electrophysiologic properties of pulmonary veins in patients with atrial fibrillation.
Journal: Journal of cardiovascular electrophysiology 20041201
Title: A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings.
Journal: Japanese heart journal 20041101
Title: The effects of class Ic antiarrhythmics on tetrodotoxin-resistant Na+ currents in rat sensory neurons.
Journal: Anesthesia and analgesia 20040801
Title: Brugada syndrome-like ST-segment elevation increase exacerbated by vomiting.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20040701
Title: Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide.
Journal: Cardiovascular drugs and therapy 20040701
Title: Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
Journal: Annals of nuclear medicine 20040501
Title: Mechanism of ST elevation and ventricular arrhythmias in an experimental Brugada syndrome model.
Journal: Circulation 20040106
Title: Brugada-like electrocardiographic pattern unmasked by fever.
Journal: Japanese heart journal 20040101
Title: Ventricular arrhythmia induced by sodium channel blocker in patients with Brugada syndrome.
Journal: Journal of the American College of Cardiology 20031105
Title: [Brugada syndrome associated with ventricular fibrillation induced by administration of pilsicainide: a case report].
Journal: Journal of cardiology 20031101
Title: Intravenous administration of class I antiarrhythmic drug induced T wave alternans in an asymptomatic Brugada syndrome patient.
Journal: Pacing and clinical electrophysiology : PACE 20030901
Title: Right bundle branch block and coved-type ST-segment elevation mimicked by acute cholecystitis.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20030901
Title: Effects of Na+ channel blocker, pilsicainide, on HERG current expressed in HEK-293 cells.
Journal: Journal of cardiovascular pharmacology 20030901
Title: [Factors for successful conversion of atrial fibrillation using intravenous injection of pilsicainide hydrochloride].
Journal: Journal of cardiology 20030801
Title: Risk stratification for asymptomatic patients with Brugada syndrome.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20030401
Title: Effect of pilsicainide on atrial electrophysiologic properties in the canine rapid atrial stimulation model.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20030401
Title: Therapeutic monitoring of class I antiarrhythmic agents using high-resolution electrocardiography instead of blood samples.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20030301
Title: Widening of the excitable gap and enlargement of the core of reentry during atrial fibrillation with a pure sodium channel blocker in canine atria.
Journal: Circulation 20030218
Title: Evaluation of the effect of bepridil on paroxysmal atrial fibrillation: relationship between efficacy and the f-f interval in surface ECG recordings.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20030101
Title: Bepridil prevents paroxysmal atrial fibrillation by a class III antiarrhythmic drug effect.
Journal: Pacing and clinical electrophysiology : PACE 20030101
Title: Enhancement of J-ST-segment elevation by the glucose and insulin test in Brugada syndrome.
Journal: Pacing and clinical electrophysiology : PACE 20030101
Title: Low-dose flecainide infusion followed by oral pilsicainide is highly effective and safe for paroxysmal atrial fibrillation.
Journal: Cardiovascular drugs and therapy 20030101
Title: Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20021001
Title: [Brugada syndrome occurring in an identical twin: a case report].
Journal: Journal of cardiology 20020901
Title: Pilsicanide-induced marked T wave alternans and ventricular fibrillation in a patient with Brugada syndrome.
Journal: Journal of cardiovascular electrophysiology 20020801
Title: Quantification of pilsicainide in serum by capillary electrophoresis.
Journal: Journal of pharmaceutical and biomedical analysis 20020720
Title: Class I antiarrhythmic drug and coronary vasospasm-induced T wave alternans and ventricular tachyarrhythmia in a patient with Brugada syndrome and vasospastic angina.
Journal: Journal of cardiovascular electrophysiology 20020201
Title: J wave and ST segment elevation in the inferior leads: a latent type of variant Brugada syndrome?
Journal: Japanese heart journal 20020101
Title: Effects of ionic remodeling on cardiac antiarrhythmic drug actions.
Journal: Journal of cardiovascular pharmacology 20011201
Title: Electropharmacologic effects of pilsicainide, a pure sodium channel blocker, on the remodeled atrium subjected to chronic rapid pacing.
Journal: Journal of cardiovascular pharmacology 20011201
Title: Images in cardiology: Successful treatment of atrial tachycardia-induced cardiomyopathy with pilsicainide.
Journal: Heart (British Cardiac Society) 20011201
Title: Paradoxic abbreviation of repolarization in epicardium of the right ventricular outflow tract during augmentation of Brugada-type ST segment elevation.
Journal: Journal of cardiovascular electrophysiology 20011201
Title: ELISA for the quantification of pilsicainide.
Journal: Biological & pharmaceutical bulletin 20011001
Title: [Efficacy of pilsicainide for the long-term prevention of paroxysmal atrial fibrillation: analysis based on the time of onset].
Journal: Journal of cardiology 20011001
Title: Appropriate dosing of pilsicainide hydrochloride in patients on hemodialysis.
Journal: Nephron 20010601
Title: ST segment elevation in the right precordial leads following administration of class Ic antiarrhythmic drugs.
Journal: Heart (British Cardiac Society) 20010101
Title: Relatively benign clinical course in asymptomatic patients with brugada-type electrocardiogram without family history of sudden death.
Journal: Journal of cardiovascular electrophysiology 20010101
Title: Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs.
Journal: Journal of electrocardiology 20010101
Title: New antiarrhythmic agents for atrial fibrillation.
Journal: Current opinion in investigational drugs (London, England : 2000) 20010101
Title: A case of sinus pause due to the proarrhythmia of pilsicainide.
Journal: Japanese heart journal 20000501
Title: General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system.
Journal: Arzneimittel-Forschung 19881001
