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883564-93-0,MFCD31715330
Catalog No.:AA01FVG6

883564-93-0 | t-butyl acetate-PEG2-CH2COOH

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250mg
97%
1 week  
$65.00   $45.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01FVG6
Chemical Name:
t-butyl acetate-PEG2-CH2COOH
CAS Number:
883564-93-0
Molecular Formula:
C12H22O7
Molecular Weight:
278.2989
MDL Number:
MFCD31715330
SMILES:
OC(=O)COCCOCCOCC(=O)OC(C)(C)C
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2006/42215,2006,A1Locationinpatent:Page/Pagecolumn40

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2006/42215,2006,A1Locationinpatent:Page/Pagecolumn40

883564-93-0   
(3S,3’S,4S,4’S)-1,1’-(2-aminoterephthaloyl)-bis(N3,N4-bis((1S,2R)-2-phenylcyclopropyl)pyrrolidine-3,4-dicarboxamide) 
 
tert-butyl2-(2-(2-(2-((2,5-bis((3S,4S)-3,4-bis(((1S,2R)-2-phenylcyclopropyl)carbamoyl)pyrrolidine-1-carbonyl)phenyl)amino)-2-oxoethoxy)ethoxy)ethoxy)acetate 

[1]CurrentPatentAssignee:THEUNIVERSITYOFTEXASSYSTEM;SCRIPPSRESEARCH-WO2018/5812,2018,A1Locationinpatent:Page/Pagecolumn269;270;274;275

883564-93-0   
4-(3,5-dimethoxy-4-(piperazin-1-ylmethyl)phenyl)-2-methyl-2,7-naphthyridin-1(2H)-onehydrochloride 
 
tert-butyl2-(2-(2-(2-(4-(2,6-dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)piperazin-1-yl)-2-oxoethoxy)ethoxy)ethoxy)acetate 

[1]Zoppi,Vittoria;Hughes,ScottJ.;Maniaci,Chiara;Testa,Andrea;Gmaschitz,Teresa;Wieshofer,Corinna;Koegl,Manfred;Riching,KristinM.;Daniels,DanetteL.;Spallarossa,Andrea;Ciulli,Alessio[JournalofMedicinalChemistry,2019,vol.62,#2,p.699-726]

[1]CurrentPatentAssignee:KYMERATHERAPEUTICSINC-US2019/192668,2019,A1

[2]CurrentPatentAssignee:KYMERATHERAPEUTICSINC-WO2020/113233,2020,A1

Literature

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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