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Home Amines 886366-20-7
886366-20-7,MFCD03646032
Catalog No.:AA008AD1

886366-20-7 | 5-Bromo-2-cyclopropylaminopyrimidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$6.00   $4.00
- +
250mg
98%
in stock  
$7.00   $5.00
- +
1g
98%
in stock  
$26.00   $18.00
- +
5g
98%
in stock  
$128.00   $89.00
- +
25g
98%
in stock  
$610.00   $427.00
- +
100g
98%
in stock  
$1,640.00   $1,148.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008AD1
Chemical Name:
5-Bromo-2-cyclopropylaminopyrimidine
CAS Number:
886366-20-7
Molecular Formula:
C7H8BrN3
Molecular Weight:
214.0625
MDL Number:
MFCD03646032
SMILES:
Brc1cnc(nc1)NC1CC1
Properties
Computed Properties
 
Complexity:
130  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.8  

Downstream Synthesis Route

[1]Zhang,Dongfeng;Li,Peng;Gao,Yongxin;Song,Yaoyao;Zhu,Yaqin;Su,Hong;Yang,Beibei;Li,Li;Li,Gang;Gong,Ningbo;Lu,Yang;Shao,Huanjie;Yu,Chunrong;Huang,Haihong[JournalofMedicinalChemistry,2021,vol.64,#11,p.7434-7452]

[2]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-WO2011/22473,2011,A1Locationinpatent:Page/Pagecolumn167-168

[3]CurrentPatentAssignee:GUANGZHOUHEALTHQUESTPHARMA-EP2594567,2013,A1Locationinpatent:Paragraph0054;0055

[4]CurrentPatentAssignee:GUANGZHOUHEALTHQUESTPHARMA-US2013/196985,2013,A1Locationinpatent:Paragraph0125;0135-0137

[5]CurrentPatentAssignee:ASTARBIOTECH-US2014/31354,2014,A1Locationinpatent:Paragraph0287;0327;0328

[6]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-US2018/296543,2018,A1Locationinpatent:Paragraph0706;0710;0711

[7]Li,Yupeng;Shen,Mengjie;Zhang,Zhang;Luo,Jinfeng;Pan,Xiaofen;Lu,Xiaoyun;Long,Huoyou;Wen,Donghai;Zhang,Fengxiang;Leng,Fang;Li,Yingjun;Tu,Zhengchao;Ren,Xiaomei;Ding,Ke[JournalofMedicinalChemistry,2012,vol.55,#22,p.10033-10046]

[8]CurrentPatentAssignee:SUN,SHUPING-CN103370324,2016,BLocationinpatent:Paragraph0167-0169

[1]Thomas,Mathew;Huang,Wei-Sheng;Wen,David;Zhu,Xiaotian;Wang,Yihan;Metcalf,ChesterA.;Liu,Shuangying;Chen,Ingrid;Romero,Jan;Zou,Dong;Sundaramoorthi,Raji;Li,Feng;Qi,Jiwei;Cai,Lisi;Zhou,Tianjun;Commodore,Lois;Xu,Qihong;Keats,Jeff;Wang,Frank;Wardwell,Scott;Ning,Yaoyu;Snodgrass,JosephT.;Broudy,MarcI.;Russian,Karin;Iuliucci,John;Rivera,VictorM.;Sawyer,TomiK.;Dalgarno,DavidC.;Clackson,Tim;Shakespeare,WilliamC.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#12,p.3743-3748]

[2]Li,Yupeng;Shen,Mengjie;Zhang,Zhang;Luo,Jinfeng;Pan,Xiaofen;Lu,Xiaoyun;Long,Huoyou;Wen,Donghai;Zhang,Fengxiang;Leng,Fang;Li,Yingjun;Tu,Zhengchao;Ren,Xiaomei;Ding,Ke[JournalofMedicinalChemistry,2012,vol.55,#22,p.10033-10046]

[3]CurrentPatentAssignee:ASTARBIOTECH-US2014/31354,2014,A1

[4]CurrentPatentAssignee:SUN,SHUPING-CN103370324,2016,B

[5]Zhang,Dongfeng;Li,Peng;Gao,Yongxin;Song,Yaoyao;Zhu,Yaqin;Su,Hong;Yang,Beibei;Li,Li;Li,Gang;Gong,Ningbo;Lu,Yang;Shao,Huanjie;Yu,Chunrong;Huang,Haihong[JournalofMedicinalChemistry,2021,vol.64,#11,p.7434-7452]

[1]Thomas,Mathew;Huang,Wei-Sheng;Wen,David;Zhu,Xiaotian;Wang,Yihan;Metcalf,ChesterA.;Liu,Shuangying;Chen,Ingrid;Romero,Jan;Zou,Dong;Sundaramoorthi,Raji;Li,Feng;Qi,Jiwei;Cai,Lisi;Zhou,Tianjun;Commodore,Lois;Xu,Qihong;Keats,Jeff;Wang,Frank;Wardwell,Scott;Ning,Yaoyu;Snodgrass,JosephT.;Broudy,MarcI.;Russian,Karin;Iuliucci,John;Rivera,VictorM.;Sawyer,TomiK.;Dalgarno,DavidC.;Clackson,Tim;Shakespeare,WilliamC.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#12,p.3743-3748]

886366-20-7    1066-54-2   
N-cyclopropyl-5-(2-(trimethylsilyl)ethynyl)pyrimidin-2-amine 

[1]Locationinpatent:schemeortableThomas,Mathew;Huang,Wei-Sheng;Wen,David;Zhu,Xiaotian;Wang,Yihan;Metcalf,ChesterA.;Liu,Shuangying;Chen,Ingrid;Romero,Jan;Zou,Dong;Sundaramoorthi,Raji;Li,Feng;Qi,Jiwei;Cai,Lisi;Zhou,Tianjun;Commodore,Lois;Xu,Qihong;Keats,Jeff;Wang,Frank;Wardwell,Scott;Ning,Yaoyu;Snodgrass,JosephT.;Broudy,MarcI.;Russian,Karin;Iuliucci,John;Rivera,VictorM.;Sawyer,TomiK.;Dalgarno,DavidC.;Clackson,Tim;Shakespeare,WilliamC.[BioorganicandMedicinalChemistryLetters,2011,vol.21,#12,p.3743-3748]

[2]Li,Yupeng;Shen,Mengjie;Zhang,Zhang;Luo,Jinfeng;Pan,Xiaofen;Lu,Xiaoyun;Long,Huoyou;Wen,Donghai;Zhang,Fengxiang;Leng,Fang;Li,Yingjun;Tu,Zhengchao;Ren,Xiaomei;Ding,Ke[JournalofMedicinalChemistry,2012,vol.55,#22,p.10033-10046]

[3]CurrentPatentAssignee:ASTARBIOTECH-US2014/31354,2014,A1Locationinpatent:Paragraph0329;0330

[4]CurrentPatentAssignee:SUN,SHUPING-CN103370324,2016,BLocationinpatent:Paragraph0170-0172

[5]Zhang,Dongfeng;Li,Peng;Gao,Yongxin;Song,Yaoyao;Zhu,Yaqin;Su,Hong;Yang,Beibei;Li,Li;Li,Gang;Gong,Ningbo;Lu,Yang;Shao,Huanjie;Yu,Chunrong;Huang,Haihong[JournalofMedicinalChemistry,2021,vol.64,#11,p.7434-7452]

Literature
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