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Home Fluorides 886503-15-7
886503-15-7,MFCD05189458
Catalog No.:AA008A1U

886503-15-7 | 2-(2,5-Difluorophenyl)pyrrolidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$71.00   $50.00
- +
5g
98%
in stock  
$350.00   $245.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008A1U
Chemical Name:
2-(2,5-Difluorophenyl)pyrrolidine
CAS Number:
886503-15-7
Molecular Formula:
C10H11F2N
Molecular Weight:
183.1978
MDL Number:
MFCD05189458
SMILES:
Fc1ccc(c(c1)C1CCCN1)F
Properties
Computed Properties
 
Complexity:
174  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2  

Downstream Synthesis Route

[1]Patent:WO2009/140128,2009,A2.Locationinpatent:Page/Pagecolumn154

[1]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2009/140128,2009,A2Locationinpatent:Page/Pagecolumn139

[1]CurrentPatentAssignee:SHANGHAIFOSUNPHARMACEUTICAL(GROUP)CO.,LTD.-CN111138333,2020,ALocationinpatent:Paragraph0091-0094

[2]CurrentPatentAssignee:JIANGSUPHARMSYNPHARMACEUTICALTECH-CN111302997,2020,ALocationinpatent:Paragraph0053;0056;0059-0060;0061;0062;0065

[3]CurrentPatentAssignee:HANDOKINC.;CMGPHARMACEUTICALCOLTD-US2016/168156,2016,A1Locationinpatent:Paragraph0175;0181;0182

[4]Lv,Xunlei;Chen,Liang;Pan,Jing;Meng,Xue;Bi,Siju;Liu,Weiyuan;Zhou,Ting;Lin,Kuaile;Ye,Deyong;Zhou,Weicheng[Chirality,2021,vol.33,#12,p.931-937]

[5]Bernhard,LauraM.;McLachlan,Jill;Gröger,Harald[OrganicProcessResearchandDevelopment,2022,vol.26,#7,p.2067-2074]

[6]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-WO2013/88256,2013,A1Locationinpatent:Page/Pagecolumn60

[7]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2014/371217,2014,A1Locationinpatent:Paragraph0568

[8]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2015/5280,2015,A1Locationinpatent:Paragraph0545-0547

[9]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2015/368238,2015,A1Locationinpatent:Paragraph0582;0584

[10]CurrentPatentAssignee:SINOBIOPHARMACEUTICALLIMITED;SHOUYAOHOLDINGSBEIJINGCOLTD-CN108003161,2018,ALocationinpatent:Paragraph0349;0350;0362-0364

[11]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2009/140128,2009,A2Locationinpatent:Page/Pagecolumn139

[12]CurrentPatentAssignee:SHOUYAOHOLDINGSBEIJINGCOLTD;SINOBIOPHARMACEUTICALLIMITED-EP3533796,2019,A1Locationinpatent:Paragraph0074;0081;0082

[13]Chen,Fei-Fei;Chen,Qi;Li,Bo-Bo;Xu,Jian-He;Zhang,Yu-Hui;Zheng,Gao-Wei;Zhou,Xin-Yi[OrganicLetters,2020,vol.22,#9,p.3367-3372]

[14]CurrentPatentAssignee:SHANGHAIFOSUNPHARMACEUTICAL(GROUP)CO.,LTD.-CN111302995,2020,ALocationinpatent:Paragraph0042-0044;0060-0062

[1]CurrentPatentAssignee:Novartis(w/oSandoz);NOVARTISAG-WO2009/140128,2009,A2

[2]CurrentPatentAssignee:SHENZHENTARGETRXINC-CN109456331,2019,A

[3]Chen,Fei-Fei;Chen,Qi;Li,Bo-Bo;Xu,Jian-He;Zhang,Yu-Hui;Zheng,Gao-Wei;Zhou,Xin-Yi[OrganicLetters,2020,vol.22,#9,p.3367-3372]

[4]CurrentPatentAssignee:JIANGSUPHARMSYNPHARMACEUTICALTECH-CN111302997,2020,A

[5]Lv,Xunlei;Chen,Liang;Pan,Jing;Meng,Xue;Bi,Siju;Liu,Weiyuan;Zhou,Ting;Lin,Kuaile;Ye,Deyong;Zhou,Weicheng[Chirality,2021,vol.33,#12,p.931-937]

[6]Bernhard,LauraM.;McLachlan,Jill;Gröger,Harald[OrganicProcessResearchandDevelopment,2022,vol.26,#7,p.2067-2074]

[1]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2014/371217,2014,A1

[2]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2015/5280,2015,A1

[3]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2015/368238,2015,A1

[4]CurrentPatentAssignee:SINOBIOPHARMACEUTICALLIMITED;SHOUYAOHOLDINGSBEIJINGCOLTD-CN108003161,2018,A

[5]CurrentPatentAssignee:SHOUYAOHOLDINGSBEIJINGCOLTD;SINOBIOPHARMACEUTICALLIMITED-EP3533796,2019,A1

Literature
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SDS
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Tags:886503-15-7 Molecular Formula|886503-15-7 MDL|886503-15-7 SMILES|886503-15-7 2-(2,5-Difluorophenyl)pyrrolidine