Home Quinolines 89-00-9
89-00-9,MFCD00006295
Catalog No.:AA00IFH0

89-00-9 | Quinolinic acid

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100g
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$15.00   $11.00
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500g
99%
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$38.00   $27.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IFH0
Chemical Name:
Quinolinic acid
CAS Number:
89-00-9
Molecular Formula:
C7H5NO4
Molecular Weight:
167.1189
MDL Number:
MFCD00006295
SMILES:
C1=CC(=C(N=C1)C(=O)O)C(=O)O
Properties
Properties
 
BP:
425 °C at 760 mmHg  
Form:
Solid  
MP:
188-190 °C (dec.)(lit.)  
Refractive Index:
1.6280 (estimate)  
Solubility:
10g/l  
Storage:
Light sensitive;Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
204  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
0.2  

Upstream Synthesis Route

[1]BioorganicandMedicinalChemistry,2001,vol.9,#8,p.2061-2071

[1]ChemischeBerichte,1895,vol.28,p.3153

[1]ChemischeBerichte,1887,vol.20,p.1351

[1]HelveticaChimicaActa,1958,vol.41,p.498,509

[1]Patent:CN102746294,2016,B,.Locationinpatent:Paragraph0077;0078

[2]Heterocycles,2002,vol.57,#10,p.1881-1890

[3]BioorganicandMedicinalChemistry,2001,vol.9,#8,p.2061-2071

[4]EuropeanJournalofMedicinalChemistry,2012,vol.55,p.58-66,9

[5]Molecules,2000,vol.5,#3,p.481-482

[6]Patent:US5801183,1998,A,

[7]ChemicalCommunications,2016,vol.52,#38,p.6471-6474

[8]Patent:CN106083846,2016,A,.Locationinpatent:Paragraph0013;0014;0015

Downstream Synthesis Route

[1]HelveticaChimicaActa,1958,vol.41,p.498,509

[1]JournaloftheIndianChemicalSociety,1933,vol.10,p.111,114

[2]Patent:CN106188047,2016,A.Locationinpatent:Paragraph0016

[1]ChemischeBerichte,1887,vol.20,p.1351

[1]ChemischeBerichte,1895,vol.28,p.3153

176967-80-9    89-00-9   
3,5-dibromo-8-nitro-quinoline 

[1]RecueildesTravauxChimiquesdesPays-Bas,1929,vol.48,p.552

Literature

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Journal: Neurobiology of disease 20120601

Title: Behavioral and histological analysis of a partial double-lesion model of parkinson-variant multiple system atrophy.

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Title: Evaluation of a multiple system atrophy model in rats using multitracer microPET.

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Title: Inducible NAD overproduction in Arabidopsis alters metabolic pools and gene expression correlated with increased salicylate content and resistance to Pst-AvrRpm1.

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Journal: Magnetic resonance in chemistry : MRC 20120501

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Journal: Journal of clinical biochemistry and nutrition 20120501

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Title: Towards a new family of photoluminescent organozinc 8-hydroxyquinolinates with a high propensity to form noncovalent porous materials.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120427

Title: Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.

Journal: Cell stem cell 20120406

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Journal: The FEBS journal 20120401

Title: Kynurenine pathway inhibition as a therapeutic strategy for neuroprotection.

Journal: The FEBS journal 20120401

Title: Quinolinic acid: neurotoxicity.

Journal: The FEBS journal 20120401

Title: The kynurenine pathway and quinolinic acid: pivotal roles in HIV associated neurocognitive disorders.

Journal: The FEBS journal 20120401

Title: Mesenchymal stem cells induced to secrete neurotrophic factors attenuate quinolinic acid toxicity: a potential therapy for Huntington's disease.

Journal: Experimental neurology 20120401

Title: Kynurenines: from the perspective of major psychiatric disorders.

Journal: The FEBS journal 20120401

Title: Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato)zincate(II) trihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20120401

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Journal: Microbiology (Reading, England) 20120301

Title: Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structure.

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Journal: Journal of psychopharmacology (Oxford, England) 20120301

Title: Potato- an important source of nutritional kynurenic acid.

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20120301

Title: Bis[[aqua-(1H-imidazo[4,5-f][1,10]phenanthroline-κN,N)cadmium]bis-(μ-pyridine-2,3-dicarboxyl-ato)-κN,O:O;κO:N,O].

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Title: Gas chromatography/tandem mass spectrometry detection of extracellular kynurenine and related metabolites in normal and lesioned rat brain.

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Title: Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum.

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Title: Regulation of quinolinic acid neosynthesis in mouse, rat and human brain by iron and iron chelators in vitro.

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Title: ConBr, a lectin from Canavalia brasiliensis seeds, protects against quinolinic acid-induced seizures in mice.

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Title: A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome.

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Journal: Behavioural brain research 20111201

Title: Impaired sensitivity to Pavlovian stimulus-outcome learning after excitotoxic lesion of the ventrolateral neostriatum.

Journal: Behavioural brain research 20111201

Title: Intracerebroventricular administration of inosine is anticonvulsant against quinolinic acid-induced seizures in mice: an effect independent of benzodiazepine and adenosine receptors.

Journal: Pharmacology, biochemistry, and behavior 20111201

Title: Poly[[hexa-aqua-(μ(2)-oxalato-κO,O:O,O)bis-(μ(3)-pyridine-2,4-dicarboxyl-ato-κN,O:O:O)dilanthanum(III)] monohydrate].

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Journal: European journal of pharmacology 20111130

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Title: Altered tryptophan metabolism in Parkinson's disease: a possible novel therapeutic approach.

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Title: Contamination of mesenchymal stem-cells with fibroblasts accelerates neurodegeneration in an experimental model of Parkinson's disease.

Journal: Stem cell reviews 20111101

Title: Tryptophan in alcoholism treatment II: inhibition of the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevation of blood acetaldehyde concentration and induction of aversion to alcohol by combined administration of tryptophan and benserazide.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20111101

Title: Tryptophan in alcoholism treatment I: kynurenine metabolites inhibit the rat liver mitochondrial low Km aldehyde dehydrogenase activity, elevate blood acetaldehyde concentration and induce aversion to alcohol.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20111101

Title: Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats.

Journal: The FEBS journal 20111101

Title: Neuroprotective effects of mesenchymal stem cell transplantation in animal model of cerebellar degeneration.

Journal: Neurological research 20111101

Title: Effect of some naturally occurring iron ion chelators on the formation of radicals in the reaction mixtures of rat liver microsomes with ADP, Fe and NADPH.

Journal: Journal of clinical biochemistry and nutrition 20111101

Title: Research on an in vitro cell system for testing the neurotoxicity of kynurenine pathway metabolites.

Journal: Die Pharmazie 20111101

Title: 6,6'-(Pyridine-2,6-di-yl)bis-(pyrrolo-[3,4-b]pyridine-5,7-dione).

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Cell signaling in NMDA preconditioning and neuroprotection in convulsions induced by quinolinic acid.

Journal: Life sciences 20111010

Title: Molecular evolution of bacterial indoleamine 2,3-dioxygenase.

Journal: Gene 20111001

Title: Human myeloid dendritic cells are refractory to tryptophan metabolites.

Journal: Human immunology 20111001

Title: Liquid chromatography/time-of-flight mass spectrometry for the analysis of plant samples: a method for simultaneous screening of common cofactors or nucleotides and application to an engineered plant line.

Journal: Plant physiology and biochemistry : PPB 20111001

Title: Indoleamine 2,3-diooxygenase in periaortic fat: mechanisms of inhibition of contraction.

Journal: American journal of physiology. Heart and circulatory physiology 20111001

Title: Unsaturated iridium pyridinedicarboxylate pincer complexes with catalytic activity in borylation of arenes.

Journal: Dalton transactions (Cambridge, England : 2003) 20110907

Title: Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis.

Journal: Journal of neurochemistry 20110901

Title: Targeting the kynurenine pathway as a potential strategy to prevent and treat Alzheimer's disease.

Journal: Medical hypotheses 20110901

Title: The tryptophan metabolite 3-hydroxyanthranilic acid plays anti-inflammatory and neuroprotective roles during inflammation: role of hemeoxygenase-1.

Journal: The American journal of pathology 20110901

Title: Systemic changes of tryptophan catabolites via the indoleamine-2,3-dioxygenase pathway in primary cervical cancer.

Journal: Anticancer research 20110801

Title: An integrated approach to characterize genetic interaction networks in yeast metabolism.

Journal: Nature genetics 20110701

Title: In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with 11C-ketoprofen methyl ester.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110701

Title: catena-Poly[[[(1,10-phenanthroline-κN,N')zinc]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O,O] monohydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110601

Title: Chloridobis(2-chloro-benz-yl)(quinolin-8-olato-κN,O)tin(IV).

Journal: Acta crystallographica. Section E, Structure reports online 20110601

Title: 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues?

Journal: Toxins 20110601

Title: Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives.

Journal: Current neuropharmacology 20110601

Title: NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways.

Journal: Behavioural brain research 20110516

Title: 2-Aminophenoxazine-3-one and 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one cause cellular apoptosis by reducing higher intracellular pH in cancer cells.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511

Title: Studies on a unique organelle localization of a liver enzyme, serine:pyruvate (or alanine:glyoxylate) aminotransferase.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511

Title: Multiple sclerosis, seizures, and antiepileptics: role of IL-18, IDO, and melatonin.

Journal: European journal of neurology 20110501

Title: Immune system to brain signaling: neuropsychopharmacological implications.

Journal: Pharmacology & therapeutics 20110501

Title: Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer.

Journal: Omics : a journal of integrative biology 20110501

Title: Proneural transcription factors Dlx2 and Pax6 are altered in adult SVZ neural precursor cells following striatal cell loss.

Journal: Molecular and cellular neurosciences 20110501

Title: catena-Poly[diimidazolium [bis-(μ-pyridine-2,5-dicarboxyl-ato)bis-[diaqua-praseodymate(III)]]-bis-(μ-pyridine-2,5-dicarboxyl-ato)].

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: Piperazine-1,4-diium pyridine-2,3-dicarboxyl-ate methanol monosolvate.

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: The new '5-HT' hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110429

Title: Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats.

Journal: Life sciences 20110425

Title: Structure and reaction mechanism in the heme dioxygenases.

Journal: Biochemistry 20110412

Title: Inflammation-associated depression: from serotonin to kynurenine.

Journal: Psychoneuroendocrinology 20110401

Title: γ-Aminobutyric acid type B receptor changes in the rat striatum and substantia nigra following intrastriatal quinolinic acid lesions.

Journal: Journal of neuroscience research 20110401

Title: Bone marrow mesenchymal stem cells can improve the motor function of a Huntington's disease rat model.

Journal: Neurological research 20110401

Title: Licofelone attenuates quinolinic acid induced Huntington like symptoms: possible behavioral, biochemical and cellular alterations.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110330

Title: Inflammation in depression: is adiposity a cause?

Journal: Dialogues in clinical neuroscience 20110301

Title: Poly[[triaqua-(μ(3)-4-oxidopyridine-2,6-dicarboxyl-ato)terbium(III)] monohydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20110301

Title: Complex formation in aqueous solution and in the solid state of the potent insulin-enhancing V(IV)O2+ compounds formed by picolinate and quinolinate derivatives.

Journal: Inorganic chemistry 20110207

Title: Attenuation of proinflammatory cytokines and apoptotic process by verapamil and diltiazem against quinolinic acid induced Huntington like alterations in rats.

Journal: Brain research 20110204

Title: Magnetic resonance imaging to assess blood-brain barrier damage in murine trypanosomiasis.

Journal: The American journal of tropical medicine and hygiene 20110204

Title: Inflammatory biomarkers and depression.

Journal: Neurotoxicity research 20110201

Title: Lead dysregulates serine/threonine protein phosphatases in human neurons.

Journal: Neurochemical research 20110201

Title: Poly[(μ(4)-pyridine-2,3-dicarboxyl-ato)lead(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

Journal: Journal of medicinal chemistry 20110127

Title: Heteronuclear (Co-Ca, Co-Ba) 2,3-pyridinedicarboxylate complexes: synthesis, structure and physico-chemical properties.

Journal: Dalton transactions (Cambridge, England : 2003) 20110114

Title: Functional gene expression profiling in yeast implicates translational dysfunction in mutant huntingtin toxicity.

Journal: The Journal of biological chemistry 20110107

Title: Comparative neuroprotective profile of statins in quinolinic acid induced neurotoxicity in rats.

Journal: Behavioural brain research 20110101

Title: Lentiviral delivery of meteorin protects striatal neurons against excitotoxicity and reverses motor deficits in the quinolinic acid rat model.

Journal: Neurobiology of disease 20110101

Title: Neuronal-immune interactions in mediating stress effects in the etiology and course of schizophrenia: role of the amygdala in developmental co-ordination.

Journal: Medical hypotheses 20110101

Title: Crystallization and preliminary X-ray crystallographic analysis of human quinolinate phosphoribosyltransferase.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20110101

Title: Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD).

Journal: Molecular neurodegeneration 20110101

Title: Neuronal degeneration in autonomic nervous system of Dystonia musculorum mice.

Journal: Journal of biomedical science 20110101

Title: The relationship between indoleamine 2,3-dioxygenase activity and post-stroke cognitive impairment.

Journal: Journal of neuroinflammation 20110101

Title: Vascular pathology and blood-brain barrier disruption in cognitive and psychiatric complications of type 2 diabetes mellitus.

Journal: Cardiovascular psychiatry and neurology 20110101

Title: Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO).

Journal: PloS one 20110101

Title: An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice to show mitochondrial permeability transition pore-driven excitotoxicity in interneurons and motoneurons.

Journal: Toxicologic pathology 20110101

Title: Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature.

Journal: Journal of medical case reports 20110101

Title: Environmental enrichment facilitates long-term potentiation in embryonic striatal grafts.

Journal: Neurorehabilitation and neural repair 20110101

Title: The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice.

Journal: PloS one 20110101

Title: Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis.

Journal: BMC medical genetics 20110101

Title: Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

Journal: PloS one 20110101

Title: HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention.

Journal: Retrovirology 20110101

Title: Adult human neurogenesis: from microscopy to magnetic resonance imaging.

Journal: Frontiers in neuroscience 20110101

Title: Neural tissue engineering using embryonic and induced pluripotent stem cells.

Journal: Stem cell research & therapy 20110101

Title: Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats.

Journal: PloS one 20110101

Title: Forebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function.

Journal: ASN neuro 20110101

Title: Toward an anti-inflammatory strategy for depression.

Journal: Frontiers in behavioral neuroscience 20110101

Title: Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome.

Journal: BMC medical genomics 20110101

Title: Tryptophan degradation in women with breast cancer: a pilot study.

Journal: BMC research notes 20110101

Title: Intragenomic diversity of Rhizobium leguminosarum bv. trifolii clover nodule isolates.

Journal: BMC microbiology 20110101

Title: The metabolic advantage of tumor cells.

Journal: Molecular cancer 20110101

Title: Risk factors for the development of depression in patients with hepatitis C taking interferon-α.

Journal: Neuropsychiatric disease and treatment 20110101

Title: The involvement of neuroinflammation and kynurenine pathway in Parkinson's disease.

Journal: Parkinson's disease 20110101

Title: Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease.

Journal: Frontiers in systems neuroscience 20110101

Title: Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease.

Journal: Neurology research international 20110101

Title: Liver Metabolic Alterations and Changes in Host Intercompartmental Metabolic Correlation during Progression of Malaria.

Journal: Journal of parasitology research 20110101

Title: A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase.

Journal: Neuropsychiatric disease and treatment 20110101

Title: HIV-1 Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38 mitogen-activated protein kinase-dependent manner.

Journal: Journal of neuroinflammation 20110101

Title: Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?

Journal: Journal of neuroinflammation 20110101

Title: Peripheral anti-inflammatory effects explain the ginsenosides paradox between poor brain distribution and anti-depression efficacy.

Journal: Journal of neuroinflammation 20110101

Title: Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models.

Journal: PloS one 20110101

Title: The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition.

Journal: Frontiers in neuroanatomy 20110101

Title: Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis.

Journal: Surgical neurology international 20110101

Title: Somatostatin receptor 1 and 5 double knockout mice mimic neurochemical changes of Huntington's disease transgenic mice.

Journal: PloS one 20110101

Title: Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders.

Journal: Molecular neurodegeneration 20110101

Title: Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts.

Journal: Journal of inflammation (London, England) 20110101

Title: Some aspects of purinergic signaling in the ventricular system of porcine brain.

Journal: Acta veterinaria Scandinavica 20110101

Title: Huntington's Disease and Striatal Signaling.

Journal: Frontiers in neuroanatomy 20110101

Title: 3-Hydroxy kynurenine treatment controls T. cruzi replication and the inflammatory pathology preventing the clinical symptoms of chronic Chagas disease.

Journal: PloS one 20110101

Title: Differential effects of accumbens core vs. shell lesions in a rat concurrent conditioned place preference paradigm for cocaine vs. social interaction.

Journal: PloS one 20110101

Title: Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis.

Journal: Molecular neurodegeneration 20110101

Title: Inducible ASABF-type antimicrobial peptide from the sponge Suberites domuncula: microbicidal and hemolytic activity in vitro and toxic effect on molluscs in vivo.

Journal: Marine drugs 20110101

Title: Tryptophan oxidative metabolism catalyzed by geobacillus stearothermophilus: a thermophile isolated from kuwait soil contaminated with petroleum hydrocarbons.

Journal: International journal of tryptophan research : IJTR 20110101

Title: Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.

Journal: International journal of tryptophan research : IJTR 20110101

Title: Acetaminophen: beyond pain and Fever-relieving.

Journal: Frontiers in pharmacology 20110101

Title: Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT)-I/II null mutant mice.

Journal: Journal of neuroinflammation 20110101

Title: Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470.

Journal: International journal of molecular imaging 20110101

Title: Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide.

Journal: Journal of neuroinflammation 20110101

Title: Cytokine production by leukocytes of military personnel with depressive symptoms after deployment to a combat-zone: a prospective, longitudinal study.

Journal: PloS one 20110101

Title: Acetylcholine and memory-enhancing activity of Ficus racemosa bark.

Journal: Pharmacognosy research 20110101

Title: Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury.

Journal: PloS one 20110101

Title: Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System.

Journal: International journal of Alzheimer's disease 20110101

Title: Gold nanoparticles in biology and medicine: recent advances and prospects.

Journal: Acta naturae 20110101

Title: Near-infrared luminescence from visible-light-sensitized hybrid materials covalently linked with tris(8-hydroxyquinolinate)-lanthanide [Er(III), Nd(III), and Yb(III)] derivatives.

Journal: The journal of physical chemistry. B 20101216

Title: Type 1 cannabinoid receptor mapping with [18F]MK-9470 PET in the rat brain after quinolinic acid lesion: a comparison to dopamine receptors and glucose metabolism.

Journal: European journal of nuclear medicine and molecular imaging 20101201

Title: Dual role of the carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase: mitochondrial-targeting signal and enzymatic activity.

Journal: Journal of biochemistry 20101201

Title: Targeting kynurenine 3-monooxygenase (KMO): implications for therapy in Huntington's disease.

Journal: CNS & neurological disorders drug targets 20101201

Title: Striatal ablation of GABAergic neurons prevents the in vivo neuroprotective effect of DCG-IV against the MPP+-induced neurotoxicity on dopaminergic nerve terminals.

Journal: Neurochemistry international 20101201

Title: Poly[hexa-aqua-hexa-kis-(μ-pyridine-2,4-dicarboxyl-ato)tricopper(II)dieuropium(III)].

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Hexaaqua-zinc(II) bis-[tris-(3-carb-oxy-pyridine-2-carboxyl-ato)zincate(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Poly[[triaqua-(μ(3)-4-oxidopyridine-2,6-dicarboxyl-ato)europium(III)] monohydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats.

Journal: Neuroscience 20101124

Title: Proteomic definition of the cell wall of Mycobacterium tuberculosis.

Journal: Journal of proteome research 20101105

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20101027

Title: Mechanism for the formation of substituted manganese(V) cyanidonitrido complexes: crystallographic and kinetic study of the substitution reactions of trans-[MnN(H2O)(CN)4]2- with monodentate pyridine and bidentate pyridine-carboxylate ligands.

Journal: Inorganic chemistry 20101018

Title: BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease.

Journal: Gene therapy 20101001

Title: Triimidazolium tris-(pyridine-2,6-di-carboxyl-ato)dysprosate(III) trihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20101001

Title: Quinolinate induces selective loss of melanin-concentrating hormone neurons, rather than orexin neurons, in the hypothalamus of mice and young rats.

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Title: Antiperoxidative and antiinflammatory effect of Sida cordifolia Linn. on quinolinic acid induced neurotoxicity.

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Title: Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii.

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Title: Molybdenum peroxo nanohybrid compounds in different structures and catalytic properties.

Journal: Journal of nanoscience and nanotechnology 20100901

Title: Molecular basis of vascular events following spinal cord injury.

Journal: Journal of medicine and life 20100815

Title: The kynurenine pathway and inflammation in amyotrophic lateral sclerosis.

Journal: Neurotoxicity research 20100801

Title: Synthesis, characterization, DNA interaction, and cytotoxicity of novel Pd(II) and Pt(II) complexes.

Journal: Journal of enzyme inhibition and medicinal chemistry 20100801

Title: Pioglitazone ameliorates behavioral, biochemical and cellular alterations in quinolinic acid induced neurotoxicity: possible role of peroxisome proliferator activated receptor-Upsilon (PPARUpsilon) in Huntington's disease.

Journal: Pharmacology, biochemistry, and behavior 20100801

Title: In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects.

Journal: Human molecular genetics 20100801

Title: Kynurenines, neurodegeneration and Alzheimer's disease.

Journal: Journal of cellular and molecular medicine 20100801

Title: Neuroprotective actions of the synthetic estrogen 17alpha-ethynylestradiol in the hippocampus.

Journal: Cellular and molecular neurobiology 20100701

Title: Acute intrastriatal administration of quinolinic acid provokes hyperphosphorylation of cytoskeletal intermediate filament proteins in astrocytes and neurons of rats.

Journal: Experimental neurology 20100701

Title: Lithium reduces apoptosis and autophagy after neonatal hypoxia-ischemia.

Journal: Cell death & disease 20100701

Title: Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression.

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Title: Selective lesions of the dorsomedial striatum impair serial spatial reversal learning in rats.

Journal: Behavioural brain research 20100626

Title: PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells.

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Title: RAFT polymerization of luminescent boron quinolate monomers.

Journal: Chemical communications (Cambridge, England) 20100607

Title: Neurotoxicity of quinolinic acid to spiral ganglion cells in rats.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100601

Title: [Analysis of quinolinic acid neurotoxicity to excitability of spiral ganglion cells and its mechanism in rat].

Journal: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20100601

Title: Developmental regulation and neuroprotective effects of striatal tonic GABAA currents.

Journal: Neuroscience 20100519

Title: Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?

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Title: On the early toxic effect of quinolinic acid: involvement of RAGE.

Journal: Neuroscience letters 20100426

Title: An analytical method for the measurement of acid metabolites of tryptophan-NAD pathway and related acids in urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415

Title: CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression.

Journal: Molecular psychiatry 20100401

Title: Autonomic, behavioral, and neural analyses of mild conditioned negative affect in marmosets.

Journal: Behavioral neuroscience 20100401

Title: 4,4'-Bipyridinium bis-(μ-4-oxo-1,4-dihydropyridine-2,6-dicarboxyl-ato)bis-[aqua-hydroxido-anti-monate(III)] dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Biomarkers predicting progression of human immunodeficiency virus-related disease.

Journal: Journal of clinical medicine research 20100401

Title: Systemic transplantation of mesenchymal stem cells can reduce cognitive and motor deficits in rats with unilateral lesions of the neostriatum.

Journal: Neurological research 20100301

Title: Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock.

Journal: Scandinavian journal of infectious diseases 20100301

Title: Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats.

Journal: Neurotoxicology 20100301

Title: Ruthenium(II)-arene complexes with functionalized pyridines: synthesis, characterization and cytotoxic activity.

Journal: European journal of medicinal chemistry 20100301

Title: Adenoviral gene delivery of pigment epithelium-derived factor protects striatal neurons from quinolinic acid-induced excitotoxicity.

Journal: Journal of neuropathology and experimental neurology 20100301

Title: Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients.

Journal: Anaesthesia and intensive care 20100301

Title: Complete genomic sequence of bacteriophage felix o1.

Journal: Viruses 20100301

Title: Capillary electrophoresis for the monitoring of carboxylic acid production by Gluconobacter oxydans.

Journal: Journal of chromatography. A 20100226

Title: Roles for cationic residues at the quinolinic acid binding site of quinolinate phosphoribosyltransferase.

Journal: Biochemistry 20100223

Title: Interactions at the 2 and 5 positions of 5-phosphoribosyl pyrophosphate are essential in Salmonella typhimurium quinolinate phosphoribosyltransferase.

Journal: Biochemistry 20100223

Title: NAD(P)H oxidase contributes to neurotoxicity in an excitotoxic/prooxidant model of Huntington's disease in rats: protective role of apocynin.

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Title: Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease.

Journal: Progress in neurobiology 20100209

Title: Neuroprotective effects of (-)-epigallocatechin-3-gallate against quinolinic acid-induced excitotoxicity via PI3K pathway and NO inhibition.

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Title: Haemostatic system, biochemical profiles, kynurenines and the prevalence of cardiovascular disease in peritoneally dialyzed patients.

Journal: Thrombosis research 20100201

Title: Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model.

Journal: Experimental neurology 20100201

Title: Longitudinal MRI and MRSI characterization of the quinolinic acid rat model for excitotoxicity: peculiar apparent diffusion coefficients and recovery of N-acetyl aspartate levels.

Journal: NMR in biomedicine 20100201

Title: Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease.

Journal: Neurotoxicity research 20100101

Title: Protective effect of tert-butylhydroquinone on the quinolinic-acid-induced toxicity in rat striatal slices: role of the Nrf2-antioxidant response element pathway.

Journal: Neuro-Signals 20100101

Title: Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20100101

Title: Hyperfibrinolysis, uPA/suPAR system, kynurenines, and the prevalence of cardiovascular disease in patients with chronic renal failure on conservative treatment.

Journal: The American journal of the medical sciences 20100101

Title: Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons.

Journal: The FEBS journal 20100101

Title: Bioanalytical inaccuracy: a threat to the integrity and efficiency of research.

Journal: Journal of psychiatry & neuroscience : JPN 20100101

Title: COX-2 inhibitors as antidepressants and antipsychotics: clinical evidence.

Journal: Current opinion in investigational drugs (London, England : 2000) 20100101

Title: Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake.

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Title: Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage.

Journal: International journal of molecular sciences 20100101

Title: NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity.

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Title: Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease.

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Title: Time-course correlation of early toxic events in three models of striatal damage: modulation by proteases inhibition.

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Title: Comparison of transplant efficiency between spontaneously derived and noggin-primed human embryonic stem cell neural precursors in the quinolinic acid rat model of Huntington's disease.

Journal: Cell transplantation 20100101

Title: Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders.

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Title: Effect of dipterinyl calcium pentahydrate on hepatitis B virus replication in transgenic mice.

Journal: Journal of translational medicine 20100101

Title: Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection.

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Title: Genetic mouse models of Huntington's disease: focus on electrophysiological mechanisms.

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Title: Pain perception in neurodevelopmental animal models of schizophrenia.

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Title: Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression.

Journal: Malaria journal 20100101

Title: Systemic levels of MMP2/TIMP2 and cardiovascular risk in CAPD patients.

Journal: Nephron. Clinical practice 20100101

Title: Kynurenine pathway - a new link between endothelial dysfunction and carotid atherosclerosis in chronic kidney disease patients.

Journal: Advances in medical sciences 20100101

Title: Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism--effects of medication.

Journal: Behavioral and brain functions : BBF 20100101

Title: Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection.

Journal: AIDS research and therapy 20100101

Title: The Waddlia genome: a window into chlamydial biology.

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Title: The Ayurvedic drug, Ksheerabala, ameliorates quinolinic acid-induced oxidative stress in rat brain.

Journal: International journal of Ayurveda research 20100101

Title: Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention.

Journal: Behavioral and brain functions : BBF 20100101

Title: A novel anti-virulence gene revealed by proteomic analysis in Shigella flexneri 2a.

Journal: Proteome science 20100101

Title: Kynurenine and its metabolites in Alzheimer's disease patients.

Journal: Advances in medical sciences 20100101

Title: Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures.

Journal: Journal of neuroinflammation 20100101

Title: Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans.

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Title: Circulating Antibodies to IDO/THO Pathway Metabolites in Alzheimer's Disease.

Journal: International journal of Alzheimer's disease 20100101

Title: Role of nicotinamide in DNA damage, mutagenesis, and DNA repair.

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Title: Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus.

Journal: Molecular brain 20100101

Title: Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease.

Journal: BMC neuroscience 20100101

Title: Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease.

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Title: Viable mouse gene ablations that robustly alter brain Aβ levels are rare.

Journal: BMC neuroscience 20100101

Title: Inflammatory responses are not sufficient to cause delayed neuronal death in ATP-induced acute brain injury.

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Title: Nucleus Accumbens Core and Shell are Necessary for Reinforcer Devaluation Effects on Pavlovian Conditioned Responding.

Journal: Frontiers in integrative neuroscience 20100101

Title: A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production.

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Title: Characterisation of the expression of NMDA receptors in human astrocytes.

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Title: Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide.

Journal: Journal of neuroinflammation 20100101

Title: Differential fate and functional outcome of lithium chloride primed adult neural progenitor cell transplants in a rat model of Huntington disease.

Journal: Stem cell research & therapy 20100101

Title: Contribution of CNS cells in NeuroAIDS.

Journal: Journal of pharmacy & bioallied sciences 20100101

Title: Molecular biology research in neuropsychiatry: India's contribution.

Journal: Indian journal of psychiatry 20100101

Title: Endogenous Kynurenine Aminotransferases Inhibitor is Proposed to Act as 'Glia Depressing Factor' (GDF).

Journal: International journal of tryptophan research : IJTR 20100101

Title: Editorial ISTRY Special Issue.

Journal: International journal of tryptophan research : IJTR 20100101

Title: On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Indoleamine 2,3-dioxygenase in human hematopoietic stem cell transplantation.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD Concentration in Human Primary Astrocytes.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Understanding the roles of the kynurenine pathway in multiple sclerosis progression.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection.

Journal: International journal of tryptophan research : IJTR 20100101

Title: Novel mechanisms of central nervous system damage in HIV infection.

Journal: HIV/AIDS (Auckland, N.Z.) 20100101

Title: Crystal structure of bovine 3-hydroxyanthranilate 3,4-dioxygenase.

Journal: Biopolymers 20091201

Title: Delayed onset of the diurnal melatonin rise in patients with Huntington's disease.

Journal: Journal of neurology 20091201

Title: Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: role in excitotoxicity.

Journal: Neurobiology of disease 20091201

Title: Profiles of the biosynthesis and metabolism of pyridine nucleotides in potatoes (Solanum tuberosum L.).

Journal: Planta 20091201

Title: Effects of caffeic acid, rofecoxib, and their combination against quinolinic acid-induced behavioral alterations and disruption in glutathione redox status.

Journal: Neuroscience bulletin 20091201

Title: Synaptotagmins in neurodegeneration.

Journal: Anatomical record (Hoboken, N.J. : 2007) 20091201

Title: p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms.

Journal: The European journal of neuroscience 20091201

Title: Effect of magnesium oxide on the activity of standard anti-epileptic drugs against experimental seizures in rats.

Journal: Indian journal of pharmacology 20091201

Title: Lactate is an alternative energy fuel to glucose in neurons under anesthesia.

Journal: Neuroreport 20091125

Title: [11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20091101

Title: Effects of rodent prefrontal lesions on object-based, visual scene memory.

Journal: Neurobiology of learning and memory 20091101

Title: Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20091101

Title: Spermine improves recognition memory deficit in a rodent model of Huntington's disease.

Journal: Neurobiology of learning and memory 20091101

Title: Mechanistic studies on the effects of nicotinamide on megakaryocytic polyploidization and the roles of NAD+ levels and SIRT inhibition.

Journal: Experimental hematology 20091101

Title: Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.

Journal: Brain : a journal of neurology 20091101

Title: The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis.

Journal: The FEBS journal 20091101

Title: Slowed progression in models of Huntington disease by adipose stem cell transplantation.

Journal: Annals of neurology 20091101

Title: Neuroprotective effect of MK-801 against intra-striatal quinolinic acid induced behavioral, oxidative stress and cellular alterations in rats.

Journal: Indian journal of experimental biology 20091101

Title: Established therapies and novel targets in the treatment of Parkinson's disease.

Journal: Expert review of clinical pharmacology 20091101

Title: Thalidomide inhibition of vascular remodeling and inflammatory reactivity in the quinolinic acid-injected rat striatum.

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Title: Nitric oxide production and monoamine oxidase activity in cancer patients during interferon-alpha therapy.

Journal: Amino acids 20091001

Title: Prefrontostriatal circuitry regulates effort-related decision making.

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Title: Acute intrastriatal administration of quinolinic acid affects the expression of the coat protein AP-2 and its interaction with membranes.

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Title: [The transcription of the amyloid precursor protein and tryptophan 2,3-dioxygenase genes are increased by aging in the rat brain].

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Title: Effects of lesions of the nucleus accumbens core on inter-temporal choice: further observations with an adjusting-delay procedure.

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Title: Remote electronic control in the regioselective reduction of succinimides: a practical, scalable synthesis of Ep4 antagonist MF-310.

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Title: Kynurenines and oxidative status are independently associated with thrombomodulin and von Willebrand factor levels in patients with end-stage renal disease.

Journal: Thrombosis research 20090901

Title: Constructing mixed-metal coordination polymers from copper(II)-pyridinedicarboxylate metalloligands.

Journal: Acta crystallographica. Section C, Crystal structure communications 20090901

Title: Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression.

Journal: Dialogues in clinical neuroscience 20090901

Title: The impact of neuroimmune dysregulation on neuroprotection and neurotoxicity in psychiatric disorders--relation to drug treatment.

Journal: Dialogues in clinical neuroscience 20090901

Title: The neurotrophic and neuroprotective effects of psychotropic agents.

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Title: Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity.

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Title: Poly[[diaqua-(ethanol)bis-(μ(3)-pyridine-2,3-dicarboxyl-ato)dimanganese(II)] monohydrate].

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Title: The anterior cingulate cortex is involved in retrieval of long-term/long-lasting but not short-term memory for step-through inhibitory avoidance in rats.

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Title: The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection.

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Title: In vitro antioxidant activity of Valeriana officinalis against different neurotoxic agents.

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Title: Effects of kynurenine metabolites on mesangial cell proliferation and gene expression.

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Title: Atorvastatin prevents hippocampal cell death due to quinolinic acid-induced seizures in mice by increasing Akt phosphorylation and glutamate uptake.

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Title: Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.

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Title: Early nerve ending rescue from oxidative damage and energy failure by L: -carnitine as post-treatment in two neurotoxic models in rat: recovery of antioxidant and reductive capacities.

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Title: Effect of caffeic acid and rofecoxib and their combination against intrastriatal quinolinic acid induced oxidative damage, mitochondrial and histological alterations in rats.

Journal: Inflammopharmacology 20090801

Title: Impulsive choice in hippocampal but not orbitofrontal cortex-lesioned rats on a nonspatial decision-making maze task.

Journal: The European journal of neuroscience 20090801

Title: Benzyl-chloridobis(quinolin-8-olato)tin(IV).

Journal: Acta crystallographica. Section E, Structure reports online 20090801

Title: Impact of co administration of selenium and quinolinic acid in the rat's brain.

Journal: Brain research 20090724

Title: New evidence on hypoglycemic effect of quinolinic acid in diabetic rats.

Journal: Pakistan journal of biological sciences : PJBS 20090715

Title: Convergent, not serial, striatal and pallidal circuits regulate opioid-induced food intake.

Journal: Neuroscience 20090707

Title: Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.

Journal: Neurotoxicity research 20090701

Title: Kynurenine, quinolinic acid--the new factors linked to carotid atherosclerosis in patients with end-stage renal disease.

Journal: Atherosclerosis 20090601

Title: Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601

Title: Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease.

Journal: Neurobiology of disease 20090601

Title: Chemokines direct neural progenitor cell migration following striatal cell loss.

Journal: Molecular and cellular neurosciences 20090601

Title: Activin A is essential for neurogenesis following neurodegeneration.

Journal: Stem cells (Dayton, Ohio) 20090601

Title: Molecular evolutionary consequences of niche restriction in Francisella tularensis, a facultative intracellular pathogen.

Journal: PLoS pathogens 20090601

Title: Targeting oxidative/nitrergic stress ameliorates motor impairment, and attenuates synaptic mitochondrial dysfunction and lipid peroxidation in two models of Huntington's disease.

Journal: Behavioural brain research 20090516

Title: Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease.

Journal: Journal of neuroscience methods 20090515

Title: Structural and photophysical studies of highly stable lanthanide complexes of tripodal 8-hydroxyquinolinate ligands based on 1,4,7-triazacyclononane.

Journal: Inorganic chemistry 20090504

Title: Simultaneous two-voxel localized (1)H-observed (13)C-edited spectroscopy for in vivo MRS on rat brain at 9.4T: Application to the investigation of excitotoxic lesions.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20090501

Title: Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.

Journal: Brain : a journal of neurology 20090501

Title: Metallothionein treatment attenuates microglial activation and expression of neurotoxic quinolinic acid following traumatic brain injury.

Journal: Neurotoxicity research 20090501

Title: Differential expression of activating transcription factor-2 and c-Jun in the immature and adult rat hippocampus following lithium-pilocarpine induced status epilepticus.

Journal: Yonsei medical journal 20090430

Title: Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats.

Journal: European journal of nutrition 20090401

Title: On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo.

Journal: Journal of neurochemistry 20090401

Title: [Effects of excess nicotinic acid on growth and the urinary excretion of B-group vitamins and the metabolism of tryptophan in weaning rats].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20090401

Title: Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum.

Journal: Neuroscience 20090303

Title: Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid.

Journal: Journal of neurochemistry 20090301

Title: Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behavior.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090301

Title: Graft outcomes influenced by co-expression of Pax7 in graft and host tissue.

Journal: Journal of anatomy 20090301

Title: Phosphodiesterase type IV inhibition prevents sequestration of CREB binding protein, protects striatal parvalbumin interneurons and rescues motor deficits in the R6/2 mouse model of Huntington's disease.

Journal: The European journal of neuroscience 20090301

Title: Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.

Journal: PLoS pathogens 20090301

Title: Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors.

Journal: Central nervous system agents in medicinal chemistry 20090301

Title: Tetra-aqua-(2,2'-diamino-4,4'-bi-1,3-thia-zole-κN,N)nickel(II) bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)nickel(II) trihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: Bis(3,5-dimethyl-1H-pyrazole-κN)(pyridine-2,6-dicarboxyl-ato-κO,N,O)copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: catena-Poly[[(pyridine-κN)copper(II)]-μ(3)-pyridine-2,6-dicarboxylato-κO:O,N,O:O].

Journal: Acta crystallographica. Section E, Structure reports online 20090301

Title: Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090218

Title: Pre-surgical training ameliorates orbitofrontal-mediated impairments in spatial reversal learning.

Journal: Behavioural brain research 20090211

Title: Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease.

Journal: Diabetes 20090201

Title: Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria.

Journal: International journal for parasitology 20090201

Title: NAD biosynthesis evolution in bacteria: lateral gene transfer of kynurenine pathway in Xanthomonadales and Flavobacteriales.

Journal: Molecular biology and evolution 20090201

Title: The natural xanthone alpha-mangostin reduces oxidative damage in rat brain tissue.

Journal: Nutritional neuroscience 20090201

Title: Prolonged survival and expression of neural markers by bone marrow-derived stem cells transplanted into brain lesions.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20090201

Title: Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity.

Journal: Journal of medicinal chemistry 20090122

Title: Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D(2/3) receptor antagonist sulpiride.

Journal: Psychopharmacology 20090101

Title: Anti-infectious activity of tryptophan metabolites in the L-tryptophan-L-kynurenine pathway.

Journal: Biological & pharmaceutical bulletin 20090101

Title: A trouble shared is a trouble halved: social context and status affect pain in mouse dyads.

Journal: PloS one 20090101

Title: Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort.

Journal: BMC gastroenterology 20090101

Title: Differential expression of neurotrophins in postnatal C57BL/6 mice striatum.

Journal: International journal of biological sciences 20090101

Title: Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders.

Journal: CNS drugs 20090101

Title: Normal aging modulates the neurotoxicity of mutant huntingtin.

Journal: PloS one 20090101

Title: New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6.

Journal: Trials 20090101

Title: Acetaminophen inhibits neuronal inflammation and protects neurons from oxidative stress.

Journal: Journal of neuroinflammation 20090101

Title: QPRT: a potential marker for follicular thyroid carcinoma including minimal invasive variant; a gene expression, RNA and immunohistochemical study.

Journal: BMC cancer 20090101

Title: Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons.

Journal: PloS one 20090101

Title: Nicotinic acid-mediated activation of both membrane and nuclear receptors towards therapeutic glucocorticoid mimetics for treating multiple sclerosis.

Journal: PPAR research 20090101

Title: The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens.

Journal: BMC microbiology 20090101

Title: Genetic characterization of type A enterotoxigenic Clostridium perfringens strains.

Journal: PloS one 20090101

Title: Activin signaling as an emerging target for therapeutic interventions.

Journal: Cell communication and signaling : CCS 20090101

Title: The excitotoxin quinolinic acid induces tau phosphorylation in human neurons.

Journal: PloS one 20090101

Title: NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats.

Journal: Journal of neuroinflammation 20090101

Title: [Tryptophan and its metabolites in renal allograft recipients].

Journal: Przeglad lekarski 20090101

Title: The formin-homology protein SmDia interacts with the Src kinase SmTK and the GTPase SmRho1 in the gonads of Schistosoma mansoni.

Journal: PloS one 20090101

Title: Quantitative assessment of stereotyped and challenged locomotion after lesion of the striatum: a 3D kinematic study in rats.

Journal: PloS one 20090101

Title: Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth.

Journal: PloS one 20090101

Title: Status epilepticus affects the gigantocellular network of the pontine reticular formation.

Journal: BMC neuroscience 20090101

Title: Breaching the blood-brain barrier as a gate to psychiatric disorder.

Journal: Cardiovascular psychiatry and neurology 20090101

Title: Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease.

Journal: Journal of neuroinflammation 20090101

Title: Acute seizure activity promotes lipid peroxidation, increased nitrite levels and adaptive pathways against oxidative stress in the frontal cortex and striatum.

Journal: Oxidative medicine and cellular longevity 20090101

Title: Aqua-(1,10-phenanthroline)(pyridine-2,6-dicarboxyl-ato)nickel(II) pyridine-2,6-di-carboxylic acid solvate tetra-hydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20090101

Title: 4,4'-Bipyridinium bis-(2-carboxy-pyridine-3-carboxyl-ate).

Journal: Acta crystallographica. Section E, Structure reports online 20090101

Title: Kynurenine pathway metabolites in humans: disease and healthy States.

Journal: International journal of tryptophan research : IJTR 20090101

Title: Paolo guidetti.

Journal: International journal of tryptophan research : IJTR 20090101

Title: Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model.

Journal: International journal of tryptophan research : IJTR 20090101

Title: Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons.

Journal: International journal of tryptophan research : IJTR 20090101

Title: The physiological action of picolinic Acid in the human brain.

Journal: International journal of tryptophan research : IJTR 20090101

Title: Effect of quinolinic acid-induced lesions of the subthalamic nucleus on performance on a progressive-ratio schedule of reinforcement: a quantitative analysis.

Journal: Behavioural brain research 20081222

Title: Effects of simvastatin on neuroprotection and modulation of Bcl-2 and BAX in the rat quinolinic acid model of Huntington's disease.

Journal: Neuroscience letters 20081219

Title: Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation.

Journal: The Journal of organic chemistry 20081205

Title: Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation.

Journal: European journal of nuclear medicine and molecular imaging 20081201

Title: Microanatomical evidences for potential of mesenchymal stem cells in amelioration of striatal degeneration.

Journal: Neurological research 20081201

Title: Changes in pyridine metabolism profile during growth of trigonelline-forming Lotus japonicus cell cultures.

Journal: Phytochemistry 20081201

Title: Exploring the mechanism of tryptophan 2,3-dioxygenase.

Journal: Biochemical Society transactions 20081201

Title: Differential gene repertoire in Mycobacterium ulcerans identifies candidate genes for patho-adaptation.

Journal: PLoS neglected tropical diseases 20081201

Title: catena-Poly[[[aqua-(1,10-phenanthroline-κN,N')cadmium(II)]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O,O] dihydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20081201

Title: Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.

Journal: Journal of medicinal chemistry 20081127

Title: Polyfunctional recognition of pyridinedicarboxylate anions with macrocyclic polyamine receptors containing heteroaromatic groups.

Journal: The Journal of organic chemistry 20081107

Title: Synthesis, characterization and fluorescence properties of novel pyridine dicarboxylic acid derivatives and corresponding Tb(III) complexes.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081101

Title: Role of the striatum in the humoral immune response to thymus-independent and thymus-dependent antigens in rats.

Journal: Immunology letters 20081030

Title: Lesions of the medial striatum in monkeys produce perseverative impairments during reversal learning similar to those produced by lesions of the orbitofrontal cortex.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081022

Title: Characterization of quinolinate synthases from Escherichia coli, Mycobacterium tuberculosis, and Pyrococcus horikoshii indicates that [4Fe-4S] clusters are common cofactors throughout this class of enzymes.

Journal: Biochemistry 20081014

Title: Migration of neurotrophic factors-secreting mesenchymal stem cells toward a quinolinic acid lesion as viewed by magnetic resonance imaging.

Journal: Stem cells (Dayton, Ohio) 20081001

Title: Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2.

Journal: Journal of neurochemistry 20081001

Title: Neurotoxic and neuroprotective metabolites of kynurenine in patients with renal cell carcinoma treated with interferon-alpha: course and relationship with psychiatric status.

Journal: Psychiatry and clinical neurosciences 20081001

Title: Characterization of L-aspartate oxidase and quinolinate synthase from Bacillus subtilis.

Journal: The FEBS journal 20081001

Title: The Arabidopsis onset of leaf death5 mutation of quinolinate synthase affects nicotinamide adenine dinucleotide biosynthesis and causes early ageing.

Journal: The Plant cell 20081001

Title: catena-Poly[[[triaqua-copper(II)]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O] monohydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20081001

Title: catena-Poly[[[diaqua-manganese(II)]-μ(3)-pyridine-2,3-dicarboxyl-ato-κN,O:O:O] dihydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20081001

Title: catena-Poly[[[aqua-cadmium(II)]bis-(μ-4-hydroxy-pyridine-2,6-dicarboxyl-ato)[aqua-cadmium(II)]di-μ-aqua] tetra-hydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20081001

Title: Binding synergy and cooperativity in dihydrodipicolinate reductase: implications for mechanism and the design of biligand inhibitors.

Journal: Biochemistry 20080923

Title: Intact intracortical microstimulation (ICMS) representations of rostral and caudal forelimb areas in rats with quinolinic acid lesions of the medial or lateral caudate-putamen in an animal model of Huntington's disease.

Journal: Brain research bulletin 20080905

Title: A functional dissociation of the anterior and posterior pedunculopontine tegmental nucleus: excitotoxic lesions have differential effects on locomotion and the response to nicotine.

Journal: Brain structure & function 20080901

Title: Quinolinate-induced rat striatal excitotoxicity impairs endoplasmic reticulum Ca2+-ATPase function.

Journal: Neurochemical research 20080901

Title: The basal ganglia and cerebellum interact in the expression of dystonic movement.

Journal: Brain : a journal of neurology 20080901

Title: Neurogenesis in the chronic lesions of multiple sclerosis.

Journal: Brain : a journal of neurology 20080901

Title: Melatonin combats molecular terrorism at the mitochondrial level.

Journal: Interdisciplinary toxicology 20080901

Title: Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: a quantitative analysis.

Journal: Behavioural brain research 20080822

Title: The [4Fe-4S] cluster of quinolinate synthase from Escherichia coli: investigation of cluster ligands.

Journal: FEBS letters 20080820

Title: Regulation of the activity of Escherichia coli quinolinate synthase by reversible disulfide-bond formation.

Journal: Biochemistry 20080819

Title: Tenascin-R promotes neuronal differentiation of embryonic stem cells and recruitment of host-derived neural precursor cells after excitotoxic lesion of the mouse striatum.

Journal: Stem cells (Dayton, Ohio) 20080801

Title: Gravity-flow open tubular cation chromatography.

Journal: Journal of separation science 20080801

Title: AAV-BDNF mediated attenuation of quinolinic acid-induced neuropathology and motor function impairment.

Journal: Gene therapy 20080701

Title: Measurement of the (14)N nuclear quadrupole resonance frequencies by the solid effect.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20080701

Title: Somatostatin in medium-sized aspiny interneurons of striatum is responsible for their preservation in quinolinic acid and N-methyl-D-asparate-induced neurotoxicity.

Journal: Journal of molecular neuroscience : MN 20080701

Title: Urinary excretory ratio of anthranilic acid/kynurenic acid as an index of the tolerable amount of tryptophan.

Journal: Bioscience, biotechnology, and biochemistry 20080701

Title: Contrasting effects of selective lesions of nucleus accumbens core or shell on inhibitory control and amphetamine-induced impulsive behaviour.

Journal: The European journal of neuroscience 20080701

Title: Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons.

Journal: Brain research 20080618

Title: Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease.

Journal: Neurobiology of disease 20080601

Title: A psychoneuroimmunological perspective to Emil Kraepelins dichotomy: schizophrenia and major depression as inflammatory CNS disorders.

Journal: European archives of psychiatry and clinical neuroscience 20080601

Title: Hot Pepper (Capsicum spp.) protects brain from sodium nitroprusside- and quinolinic acid-induced oxidative stress in vitro.

Journal: Journal of medicinal food 20080601

Title: AAV-mediated expression of Bcl-xL or XIAP fails to induce neuronal resistance against quinolinic acid-induced striatal lesioning.

Journal: Neuroscience letters 20080516

Title: An organotellurium compound with antioxidant activity against excitotoxic agents without neurotoxic effects in brain of rats.

Journal: Brain research bulletin 20080515

Title: Antioxidant and iron-binding properties of curcumin, capsaicin, and S-allylcysteine reduce oxidative stress in rat brain homogenate.

Journal: Journal of agricultural and food chemistry 20080514

Title: Expression profiles of the organic acid metabolism-associated genes during rat liver regeneration.

Journal: Amino acids 20080501

Title: Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine.

Journal: Journal of neurochemistry 20080501

Title: Kynurenine pathway metabolism in human blood-brain-barrier cells: implications for immune tolerance and neurotoxicity.

Journal: Journal of neurochemistry 20080501

Title: Neurotoxic lesions of the medial prefrontal cortex or medial striatum impair multiple-location place learning in the water task: evidence for neural structures with complementary roles in behavioural flexibility.

Journal: Experimental brain research 20080501

Title: Expression of amphetamine sensitization is associated with recruitment of a reactive neuronal population in the nucleus accumbens core.

Journal: Psychopharmacology 20080501

Title: DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080501

Title: A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression.

Journal: Stress (Amsterdam, Netherlands) 20080501

Title: Suppression of activity in the forelimb motor cortex temporarily enlarges forelimb representation in the homotopic cortex in adult rats.

Journal: The European journal of neuroscience 20080501

Title: Quinolinic acid induced neurodegeneration in the striatum: a combined in vivo and in vitro analysis of receptor changes and microglia activation.

Journal: European journal of nuclear medicine and molecular imaging 20080401

Title: Effect of quinolinic acid-induced lesions of the nucleus accumbens core on performance on a progressive ratio schedule of reinforcement: implications for inter-temporal choice.

Journal: Psychopharmacology 20080401

Title: Indoleamine 2,3-dioxygenase-dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model.

Journal: The Journal of allergy and clinical immunology 20080401

Title: Effect of PK11195 on attenuating the enhancement of glucose utilization induced by quinolinic acid infusion in the rat brain.

Journal: Synapse (New York, N.Y.) 20080401

Title: Bax deficiency promotes an up-regulation of Bim(EL) and Bak during striatal and cortical postnatal development, and after excitotoxic injury.

Journal: Molecular and cellular neurosciences 20080401

Title: Excitotoxic neuronal death and the pathogenesis of Huntington's disease.

Journal: Archives of medical research 20080401

Title: Comprehensive X-ray structural studies of the quinolinate phosphoribosyl transferase (BNA6) from Saccharomyces cerevisiae.

Journal: Biochemistry 20080401

Title: Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions.

Journal: Neuroscience 20080327

Title: Spermine attenuates behavioral and biochemical alterations induced by quinolinic acid in the striatum of rats.

Journal: Brain research 20080310

Title: Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by quinolinic acid.

Journal: Neurobiology of disease 20080301

Title: Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques.

Journal: Psychopharmacology 20080301

Title: Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling.

Journal: Neurobiology of disease 20080301

Title: Cytoplasmic calcium mediates oxidative damage in an excitotoxic /energetic deficit synergic model in rats.

Journal: The European journal of neuroscience 20080301

Title: Pharmacodynamics of memantine: an update.

Journal: Current neuropharmacology 20080301

Title: Hepatic alteration of tryptophan metabolism in an acute porphyria model Its relation with gluconeogenic blockage.

Journal: Biochemical pharmacology 20080201

Title: Neurotoxic damage to the dorsomedial striatum exaggerates the behavioral influence of a context-specific inhibitory association mediated by the ventral hippocampus.

Journal: Behavioral neuroscience 20080201

Title: Poly[propane-1,3-diammonium [cuprate(II)-bis-(μ(2)-pyridine-2,3-dicarboxyl-ato)] trihydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: catena-Poly[[triaqua-cadmium(II)]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O].

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: catena-Poly[[[diaqua-iron(II)]-μ-pyridine-2,5-dicarboxyl-ato-[tetra-aqua-iron(II)]-μ-pyridine-2,5-dicarboxyl-ato] tetra-hydrate].

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: Behavioural and neurochemical characterization of the adenosine A2A receptor antagonist ST1535.

Journal: European journal of pharmacology 20080128

Title: Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys.

Journal: Behavioural brain research 20080125

Title: Quinolinic acid-induced seizures stimulate glutamate uptake into synaptic vesicles from rat brain: effects prevented by guanine-based purines.

Journal: Neurochemical research 20080101

Title: The association between tick-borne infections, Lyme borreliosis and autism spectrum disorders.

Journal: Medical hypotheses 20080101

Title: Microglial activation, macrophage infiltration, and evidence of cell death in the fetal brain after uteroplacental administration of lipopolysaccharide in sheep in late gestation.

Journal: American journal of obstetrics and gynecology 20080101

Title: Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model.

Journal: Arthritis research & therapy 20080101

Title: Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice.

Journal: Epilepsia 20080101

Title: Human embryonic stem cells: preclinical perspectives.

Journal: Journal of translational medicine 20080101

Title: Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease.

Journal: Journal of neuroinflammation 20080101

Title: Investigation of Zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) Porphyrazine for Application as Photosensitizer in Photodynamic Therapy of Cancer.

Journal: Metal-based drugs 20080101

Title: Transplants of encapsulated rat choroid plexus cells exert neuroprotection in a rodent model of Huntington's disease.

Journal: Cell transplantation 20080101

Title: Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia.

Journal: Journal of neuroinflammation 20080101

Title: Pillaring of CdCl2-like layers in lanthanide metal-organic frameworks: synthesis, structure, and photophysical properties.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult.

Journal: Journal of neuroinflammation 20080101

Title: Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells.

Journal: International journal of medical sciences 20080101

Title: Iron porphyrinate Fe(TPPS) reduces brain cell damage in rats intrastriatally lesioned by quinolinate.

Journal: Neurotoxicology and teratology 20080101

Title: Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.

Journal: Journal of neuroinflammation 20080101

Title: Potential developmental neurotoxicity of pesticides used in Europe.

Journal: Environmental health : a global access science source 20080101

Title: Excitation Control: Balancing PSD-95 Function at the Synapse.

Journal: Frontiers in molecular neuroscience 20080101

Title: A possible central mechanism in autism spectrum disorders, part 1.

Journal: Alternative therapies in health and medicine 20080101

Title: Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder.

Journal: BMC medical genetics 20080101

Title: A role for non-antimicrobial actions of tetracyclines in combating oxidative stress in periodontal and metabolic diseases: a literature review.

Journal: The open dentistry journal 20080101

Title: HIV-1 Antigens in Neurons of Cocaine-Abusing Patients.

Journal: The open virology journal 20080101

Title: Psychological factors in asthma.

Journal: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101

Title: Piperazinediium bis-(2-carboxy-pyridine-3-carboxyl-ate).

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Evaluation of glutathione metabolism in NMDA preconditioning against quinolinic acid-induced seizures in mice cerebral cortex and hippocampus.

Journal: Brain research 20071212

Title: Citicoline is not protective in experimental models of Huntington's disease.

Journal: Neurobiology of aging 20071201

Title: IDO expression in the brain: a double-edged sword.

Journal: Journal of molecular medicine (Berlin, Germany) 20071201

Title: Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071201

Title: N-methyl-D-aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus.

Journal: Journal of neuroscience research 20071201

Title: Tryptophan, adenosine, neurodegeneration and neuroprotection.

Journal: Metabolic brain disease 20071201

Title: The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation.

Journal: Neuro endocrinology letters 20071201

Title: 4-pyridone-3-carboxamide ribonucleoside triphosphate accumulating in erythrocytes in end stage renal failure originates from tryptophan metabolism.

Journal: Clinical and experimental medicine 20071201

Title: The involvement of astrocytes and kynurenine pathway in Alzheimer's disease.

Journal: Neurotoxicity research 20071201

Title: Cannabinoids in health and disease.

Journal: Dialogues in clinical neuroscience 20071201

Title: A series of lanthanide-transition metal frameworks based on 1-, 2-, and 3D metal-organic motifs linked by different 1D copper(I) halide motifs.

Journal: Inorganic chemistry 20071126

Title: The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression.

Journal: Molecular psychiatry 20071101

Title: Effects of quinolinic acid-induced lesions of the nucleus accumbens core on inter-temporal choice: a quantitative analysis.

Journal: Psychopharmacology 20071101

Title: Time-related changes in constitutive and inducible nitric oxide synthases in the rat striatum in a model of Huntington's disease.

Journal: Neurotoxicology 20071101

Title: IDO expands human CD4+CD25high regulatory T cells by promoting maturation of LPS-treated dendritic cells.

Journal: European journal of immunology 20071101

Title: Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens.

Journal: Journal of molecular biology 20071026

Title: Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20071001

Title: IFN-gamma-induced IDO and WRS expression in microglia is differentially regulated by IL-4.

Journal: Glia 20071001

Title: Inflammation, depression and dementia: are they connected?

Journal: Neurochemical research 20071001

Title: The role of Phe181 in the hexamerization of Helicobacter pylori quinolinate phosphoribosyltransferase.

Journal: The protein journal 20071001

Title: Altered kynurenine metabolism correlates with infarct volume in stroke.

Journal: The European journal of neuroscience 20071001

Title: Distinct contributions of frontal areas to emotion and social behaviour in the rat.

Journal: The European journal of neuroscience 20071001

Title: Central tegmental field and sexual behavior in the male rat: effects of neurotoxic lesions.

Journal: Neuroscience 20070921

Title: Poly(ADP-ribose) polymerase-1 is involved in the neuronal death induced by quinolinic acid in rats.

Journal: Neuroscience letters 20070920

Title: A comparison between the determination of free Pb(II) by two techniques: absence of gradients and Nernstian equilibrium stripping and resin titration.

Journal: Analytica chimica acta 20070905

Title: L-NAME reverses quinolinic acid-induced toxicity in rat corticostriatal slices: Involvement of src family kinases.

Journal: Journal of neuroscience research 20070901

Title: The anti-allergic drug, N-(3',4'-dimethoxycinnamonyl) anthranilic acid, exhibits potent anti-inflammatory and analgesic properties in arthritis.

Journal: Rheumatology (Oxford, England) 20070901

Title: Adenosine A(2A) receptors modulate BDNF both in normal conditions and in experimental models of Huntington's disease.

Journal: Purinergic signalling 20070901

Title: Dopamine receptor activation reveals a novel, kynurenate-sensitive component of striatal N-methyl-D-aspartate neurotoxicity.

Journal: Neuroscience 20070810

Title: Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions.

Journal: Neuroscience letters 20070809

Title: Involvement of P-glycoprotein and multidrug resistance associated protein 1 in the transport of tanshinone IIB, a primary active diterpenoid quinone from the roots of Salvia miltiorrhiza, across the blood-brain barrier.

Journal: Drug metabolism letters 20070801

Title: An operant serial implicit learning task (SILT) in rats: task acquisition, performance and the effects of striatal lesions.

Journal: Journal of neuroscience methods 20070730

Title: Changes in neuronal protein expression in LP-BM5-infected mice.

Journal: Neuroscience letters 20070711

Title: The role of the agranular insular cortex in anticipation of reward contrast.

Journal: Neurobiology of learning and memory 20070701

Title: nadA and nadB of Shigella flexneri 5a are antivirulence loci responsible for the synthesis of quinolinate, a small molecule inhibitor of Shigella pathogenicity.

Journal: Microbiology (Reading, England) 20070701

Title: Different transfer of nociceptive sensitivity from rats with postnatal hippocampal lesions to control rats.

Journal: The European journal of neuroscience 20070701

Title: Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070701

Title: Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.

Journal: Biochemistry 20070626

Title: Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders.

Journal: Journal of the neurological sciences 20070615

Title: Temporal profile of subventricular zone progenitor cell migration following quinolinic acid-induced striatal cell loss.

Journal: Neuroscience 20070608

Title: Effect of prefrontal cortex inactivation on behavioral and neurochemical abnormalities in rats with excitotoxic lesions of the entorhinal cortex.

Journal: Synapse (New York, N.Y.) 20070601

Title: AAV-mediated delivery of BDNF augments neurogenesis in the normal and quinolinic acid-lesioned adult rat brain.

Journal: The European journal of neuroscience 20070601

Title: Plastic changes in the vibrissa motor cortex in adult rats after output suppression in the homotopic cortex.

Journal: The European journal of neuroscience 20070601

Title: Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070601

Title: Neuropsychiatric manifestations of depression in multiple sclerosis: neuroinflammatory, neuroendocrine, and neurotrophic mechanisms in the pathogenesis of immune-mediated depression.

Journal: Dialogues in clinical neuroscience 20070601

Title: Nuclear factor-kappaB-dependent cyclin D1 induction and DNA replication associated with N-methyl-D-aspartate receptor-mediated apoptosis in rat striatum.

Journal: Journal of neuroscience research 20070501

Title: Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration.

Journal: Journal of neuropathology and experimental neurology 20070501

Title: Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.

Journal: Current drug metabolism 20070501

Title: Neurotoxic lesions of the caudate-putamen on a reaching for food task in the rat: acute sensorimotor neglect and chronic qualitative motor impairment follow lateral lesions and improved success follows medial lesions.

Journal: Neuroscience 20070425

Title: Dopamine efflux in the nucleus accumbens during within-session extinction, outcome-dependent, and habit-based instrumental responding for food reward.

Journal: Psychopharmacology 20070401

Title: Interleukin-1beta but not tumor necrosis factor-alpha potentiates neuronal damage by quinolinic acid: protection by an adenosine A2A receptor antagonist.

Journal: Journal of neuroscience research 20070401

Title: Identification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK.

Journal: Molecular microbiology 20070401

Title: Non-steroidal anti-inflammatory agents, tolmetin and sulindac attenuate quinolinic acid (QA)-induced oxidative stress in primary hippocampal neurons and reduce QA-induced spatial reference memory deficits in male Wistar rats.

Journal: Life sciences 20070320

Title: Hippocalcin protects hippocampal neurons against excitotoxin damage by enhancing calcium extrusion.

Journal: Neuroscience 20070316

Title: Investigation of the antioxidant activity of African potato (Hypoxis hemerocallidea).

Journal: Journal of agricultural and food chemistry 20070307

Title: Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease.

Journal: Experimental brain research 20070301

Title: Depletion of neutrophils reduces neuronal degeneration and inflammatory responses induced by quinolinic acid in vivo.

Journal: Glia 20070301

Title: Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy.

Journal: Journal of neurochemistry 20070301

Title: Perinatal kynurenine 3-hydroxylase inhibition in rodents: pathophysiological implications.

Journal: Journal of neuroscience research 20070301

Title: Factors in AIDS dementia complex trial design: results and lessons from the abacavir trial.

Journal: PLoS clinical trials 20070301

Title: Dietary protein level and dietary interaction affect quinolinic acid concentration in rats.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070301

Title: Potential of adult neural stem cells for cellular therapy.

Journal: Biologics : targets & therapy 20070301

Title: Determination of kynurenine levels in rat plasma by high-performance liquid chromatography with pre-column fluorescence derivatization.

Journal: Analytica chimica acta 20070219

Title: Mechanisms by which acyclovir reduces the oxidative neurotoxicity and biosynthesis of quinolinic acid.

Journal: Life sciences 20070213

Title: Environmental enrichment brings a beneficial effect on beam walking and enhances the migration of doublecortin-positive cells following striatal lesions in rats.

Journal: Neuroscience 20070209

Title: Heterologous expression and purification of kynurenine-3-monooxygenase from Pseudomonas fluorescens strain 17400.

Journal: Protein expression and purification 20070201

Title: In vitro effect of quinolinic acid on energy metabolism in brain of young rats.

Journal: Neuroscience research 20070201

Title: Beneficial effects of rolipram in a quinolinic acid model of striatal excitotoxicity.

Journal: Neurobiology of disease 20070201

Title: Excess dietary lysine increases growth of chicks fed niacin-deficient diets, but dietary quinolinic acid has no niacin-sparing activity.

Journal: Poultry science 20070201

Title: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism.

Journal: The FEBS journal 20070201

Title: Adenosine A2A receptor blockade before striatal excitotoxic lesions prevents long term behavioural disturbances in the quinolinic rat model of Huntington's disease.

Journal: Behavioural brain research 20070125

Title: Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors.

Journal: Neuroscience 20070119

Title: Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis.

Journal: Biochemistry 20070109

Title: Integrative hypothesis for Huntington's disease: a brief review of experimental evidence.

Journal: Physiological research 20070101

Title: Proteasome activator enhances survival of Huntington's disease neuronal model cells.

Journal: PloS one 20070101

Title: Mechanisms of copper ion mediated Huntington's disease progression.

Journal: PloS one 20070101

Title: Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli.

Journal: BMC bioinformatics 20070101

Title: Stem cell therapy for autism.

Journal: Journal of translational medicine 20070101

Title: Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat.

Journal: Journal of neuroinflammation 20070101

Title: Animal models of Huntington's disease.

Journal: ILAR journal 20070101

Title: Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase.

Journal: BMC structural biology 20070101

Title: Aging reduces the neuroprotective capacity, VEGF secretion, and metabolic activity of rat choroid plexus epithelial cells.

Journal: Cell transplantation 20070101

Title: Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice.

Journal: BMC genomics 20070101

Title: Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains.

Journal: The European journal of neuroscience 20061201

Title: Morphological and cellular changes within embryonic striatal grafts associated with enriched environment and involuntary exercise.

Journal: The European journal of neuroscience 20061201

Title: Evidence that quinolinic acid severely impairs energy metabolism through activation of NMDA receptors in striatum from developing rats.

Journal: Journal of neurochemistry 20061201

Title: Therapeutic Strategies in Huntington's Disease.

Journal: Journal of clinical neurology (Seoul, Korea) 20061201

Title: Sensitive femtosecond coherent anti-Stokes Raman spectroscopy discrimination between dipicolinic acid and dinicotinic acid.

Journal: Optics letters 20061101

Title: Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment.

Journal: Clinical and experimental pharmacology & physiology 20061101

Title: Is the functional interaction between adenosine A(2A) receptors and metabotropic glutamate 5 receptors a general mechanism in the brain? Differences and similarities between the striatum and the hippocampus.

Journal: Purinergic signalling 20061101

Title: Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease.

Journal: Neuroreport 20061023

Title: Synthesis, structure and fluorescent studies of novel uranium coordination polymers in the pyridinedicarboxylic acid system.

Journal: Dalton transactions (Cambridge, England : 2003) 20061021

Title: Nucleus accumbens lesions decrease sensitivity to rapid changes in the delay to reinforcement.

Journal: Behavioural brain research 20061016

Title: The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum.

Journal: Neuropharmacology 20061001

Title: Inflammation and depression: is there a causal connection with dementia?

Journal: Neurotoxicity research 20061001

Title: Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains.

Journal: The European journal of neuroscience 20061001

Title: Combined minocycline plus pyruvate treatment enhances effects of each agent to inhibit inflammation, oxidative damage, and neuronal loss in an excitotoxic animal model of Huntington's disease.

Journal: Neuroscience 20060915

Title: Crystal structure of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase: insight into the active site and catalytic mechanism of a novel decarboxylation reaction.

Journal: Biochemistry 20060905

Title: Non-steroidal anti-inflammatory agents, tolmetin and sulindac, attenuate oxidative stress in rat brain homogenate and reduce quinolinic acid-induced neurodegeneration in rat hippocampal neurons.

Journal: Metabolic brain disease 20060901

Title: Acetylsalicylic acid and acetaminophen protect against oxidative neurotoxicity.

Journal: Metabolic brain disease 20060901

Title: Interferon-induced depressive illness in hep C patients responds to SSRI antidepressant treatments.

Journal: Neuropsychiatric disease and treatment 20060901

Title: Tryptophan metabolism in the central nervous system: medical implications.

Journal: Expert reviews in molecular medicine 20060831

Title: Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro.

Journal: Brain research 20060830

Title: A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060801

Title: Time course of oxidative events in the hippocampus following intracerebroventricular infusion of quinolinic acid in mice.

Journal: Neuroscience research 20060801

Title: Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys.

Journal: Neurobiology of disease 20060801

Title: Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice.

Journal: Neurobiology of disease 20060701

Title: Early steps in the biosynthesis of NAD in Arabidopsis start with aspartate and occur in the plastid.

Journal: Plant physiology 20060701

Title: Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060701

Title: Protective effects of PACAP in excitotoxic striatal lesion.

Journal: Annals of the New York Academy of Sciences 20060701

Title: The role of the dorsolateral tegmentum in the control of male sexual behavior: a reevaluation.

Journal: Behavioural brain research 20060630

Title: Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.

Journal: Cell 20060616

Title: The effects of lateralized training on spontaneous forelimb preference, lesion deficits, and graft-mediated functional recovery after unilateral striatal lesions in rats.

Journal: Experimental neurology 20060601

Title: Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease.

Journal: Experimental neurology 20060601

Title: Quinolinic acid modulates the activity of src family kinases in rat striatum: in vivo and in vitro studies.

Journal: Journal of neurochemistry 20060601

Title: 4-chloro-3-hydroxyanthranilate reduces local quinolinic acid synthesis, improves functional recovery, and preserves white matter after spinal cord injury.

Journal: Journal of neurotrauma 20060601

Title: Is the L-tryptophan metabolite quinolinic acid responsible for eosinophilic fasciitis?

Journal: Clinical and experimental medicine 20060601

Title: Changes in the immune system in depression and dementia: causal or coincidental effects?

Journal: Dialogues in clinical neuroscience 20060601

Title: Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060531

Title: Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Immunopathogenesis of cerebral malaria.

Journal: International journal for parasitology 20060501

Title: Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease.

Journal: Journal of neuroscience methods 20060415

Title: Normal sensitivity to excitotoxicity in a transgenic Huntington's disease rat.

Journal: Brain research bulletin 20060414

Title: Crystal structure of 3-hydroxyanthranilic acid 3,4-dioxygenase from Saccharomyces cerevisiae: a special subgroup of the type III extradiol dioxygenases.

Journal: Protein science : a publication of the Protein Society 20060401

Title: Gene expression changes by amyloid beta peptide-stimulated human postmortem brain microglia identify activation of multiple inflammatory processes.

Journal: Journal of leukocyte biology 20060301

Title: Inhibition of nociceptive responses of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla.

Journal: Journal of neuroscience research 20060301

Title: Lesion of the caudal ventrolateral medulla prevents the induction of hypertension by adenosine receptor blockade in rats.

Journal: Brain research 20060216

Title: Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion.

Journal: Experimental neurology 20060201

Title: Wild-type huntingtin protects neurons from excitotoxicity.

Journal: Journal of neurochemistry 20060201

Title: Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs.

Journal: Brain research 20060119

Title: Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: Implications for Huntington's disease.

Journal: Experimental neurology 20060101

Title: Tryptophan metabolism and oxidative stress in patients with chronic brain injury.

Journal: European journal of neurology 20060101

Title: Striatal modulation of cAMP-response-element-binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington's disease.

Journal: The European journal of neuroscience 20060101

Title: Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation.

Journal: Journal of neuroinflammation 20060101

Title: Melatonin in Alzheimer's disease and other neurodegenerative disorders.

Journal: Behavioral and brain functions : BBF 20060101

Title: HIV-1 associated dementia: symptoms and causes.

Journal: Retrovirology 20060101

Title: NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions.

Journal: Journal of experimental botany 20060101

Title: Gene expression in cortex and hippocampus during acute pneumococcal meningitis.

Journal: BMC biology 20060101

Title: Glutamate receptors in neuroinflammatory demyelinating disease.

Journal: Mediators of inflammation 20060101

Title: Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway.

Journal: BMC genomics 20060101

Title: Kynurenines, Parkinson's disease and other neurodegenerative disorders: preclinical and clinical studies.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Human malarial disease: a consequence of inflammatory cytokine release.

Journal: Malaria journal 20060101

Title: HIV neurotoxicity: potential therapeutic interventions.

Journal: Journal of biomedicine & biotechnology 20060101

Title: Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease.

Journal: BMC neuroscience 20060101

Title: In vitro culture duration does not impact the ability of encapsulated choroid plexus transplants to prevent neurological deficits in an excitotoxin-lesioned rat model of Huntington's disease.

Journal: Cell transplantation 20060101

Title: Selenium reduces the proapoptotic signaling associated to NF-kappaB pathway and stimulates glutathione peroxidase activity during excitotoxic damage produced by quinolinate in rat corpus striatum.

Journal: Synapse (New York, N.Y.) 20051215

Title: Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy.

Journal: Brain research bulletin 20051215

Title: Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism.

Journal: Biochemical and biophysical research communications 20051209

Title: Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20051201

Title: Long-term functional consequences of quinolinic acid striatal lesions and their alteration following an addition of a globus pallidus lesion assessed using pharmacological magnetic resonance imaging.

Journal: Experimental neurology 20051201

Title: Transplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damage.

Journal: Journal of neuroscience research 20051201

Title: Deprenyl enhances the striatal neuronal damage produced by quinolinic acid.

Journal: Brain research. Molecular brain research 20051118

Title: Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum.

Journal: Neurobiology of disease 20051101

Title: Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity.

Journal: Neurobiology of disease 20051101

Title: Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites.

Journal: American journal of physiology. Cell physiology 20051101

Title: Neuronal localization of indoleamine 2,3-dioxygenase in mice.

Journal: Neuroscience letters 20051021

Title: Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.

Journal: Blood 20051001

Title: Melatonin neutralizes neurotoxicity induced by quinolinic acid in brain tissue culture.

Journal: Journal of pineal research 20051001

Title: The uncoupling agent 2,4-dinitrophenol improves mitochondrial homeostasis following striatal quinolinic acid injections.

Journal: Journal of neurotrauma 20051001

Title: [Animal models of parkinsonism].

Journal: Revue neurologique 20051001

Title: Quantitative analysis of the generation of different striatal neuronal subtypes in the adult brain following excitotoxic injury.

Journal: Experimental neurology 20050901

Title: Cerebrospinal fluid and serum markers of inflammation in autism.

Journal: Pediatric neurology 20050901

Title: Kynurenic acid inhibits the release of the neurotrophic fibroblast growth factor (FGF)-1 and enhances proliferation of glia cells, in vitro.

Journal: Cellular and molecular neurobiology 20050901

Title: Riluzole improves motor deficits and attenuates loss of striatal neurons in a sequential double lesion rat model of striatonigral degeneration (parkinson variant of multiple system atrophy).

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20050801

Title: Kynurenine metabolism in multiple sclerosis.

Journal: Acta neurologica Scandinavica 20050801

Title: Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus.

Journal: Neuropathology and applied neurobiology 20050801

Title: Quinolinic acid toxicity on orexin neurons blocked by gamma aminobutyric acid type A receptor stimulation.

Journal: Neuroreport 20050801

Title: Pig xenografts to the immunocompetent rat brain: Survival rates using distinct neurotoxic lesions in the nigrostriatal pathway and two rat strains.

Journal: Experimental neurology 20050801

Title: The nadA gene of Pseudomonas fluorescens PGPR strain 267.1.

Journal: Current microbiology 20050801

Title: Three-dimensional 3d-4f heterometallic coordination polymers: synthesis, structures, and magnetic properties.

Journal: Inorganic chemistry 20050725

Title: Analysis of the heteromeric CsdA-CsdE cysteine desulfurase, assisting Fe-S cluster biogenesis in Escherichia coli.

Journal: The Journal of biological chemistry 20050722

Title: Crystal structure of the NAD biosynthetic enzyme quinolinate synthase.

Journal: The Journal of biological chemistry 20050722

Title: Quinolinate synthetase, an iron-sulfur enzyme in NAD biosynthesis.

Journal: FEBS letters 20050704

Title: Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model.

Journal: Neuroscience research 20050701

Title: Glucocorticoid enhances the neurotoxic actions of quinolinic acid in the striatum in a cell-specific manner.

Journal: Journal of neuroendocrinology 20050701

Title: Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys.

Journal: Movement disorders : official journal of the Movement Disorder Society 20050701

Title: 6-Hydroxymelatonin protects against quinolinic-acid-induced oxidative neurotoxicity in the rat hippocampus.

Journal: The Journal of pharmacy and pharmacology 20050701

Title: Aciclovir protects against quinolinic-acid-induced oxidative neurotoxicity.

Journal: The Journal of pharmacy and pharmacology 20050701

Title: Role of kynurenines in the central and peripheral nervous systems.

Journal: Current neurovascular research 20050701

Title: Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype.

Journal: Biochimica et biophysica acta 20050620

Title: Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds.

Journal: Journal of experimental botany 20050601

Title: The vulnerability of striatal projection neurons and interneurons to excitotoxicity is differentially regulated by dopamine during development.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050601

Title: Cytokine regulation of tryptophan metabolism in the hypothalamic-pituitary-adrenal (HPA) axis: implications for protective and toxic consequences in neuroendocrine regulation.

Journal: Cellular and molecular neurobiology 20050601

Title: Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade.

Journal: Purinergic signalling 20050601

Title: The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilate.

Journal: Biochemistry 20050531

Title: Structural studies on 3-hydroxyanthranilate-3,4-dioxygenase: the catalytic mechanism of a complex oxidation involved in NAD biosynthesis.

Journal: Biochemistry 20050531

Title: Escherichia coli quinolinate synthetase does indeed harbor a [4Fe-4S] cluster.

Journal: Journal of the American Chemical Society 20050525

Title: In vivo effects of local activation and blockade of 5-HT1B receptors on globus pallidus neuronal spiking.

Journal: Brain research 20050510

Title: Crystal structure of a nicotinate phosphoribosyltransferase from Thermoplasma acidophilum.

Journal: The Journal of biological chemistry 20050506

Title: Tryptophan metabolism and oxidative stress in patients with Huntington's disease.

Journal: Journal of neurochemistry 20050501

Title: [Evaluation of the survival of bone marrow mononucleate cells transplanted in a rat model of striatal lesion with quinolinic acid].

Journal: Revista de neurologia 20050501

Title: Involvement of the rat anterior cingulate cortex in control of instrumental responses guided by reward expectancy.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20050501

Title: Serotonin 5-HT4 receptors and their mRNAs in rat and guinea pig brain: distribution and effects of neurotoxic lesions.

Journal: The Journal of comparative neurology 20050418

Title: Susceptibility to excitotoxic and metabolic striatal neurodegeneration in the mouse is genotype dependent.

Journal: Brain research 20050408

Title: In vivo imaging of adenosine A2A receptors in rat and primate brain using [11C]SCH442416.

Journal: European journal of nuclear medicine and molecular imaging 20050401

Title: Substrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions.

Journal: American journal of physiology. Renal physiology 20050401

Title: 'Compulsive' lever pressing in rats is enhanced following lesions to the orbital cortex, but not to the basolateral nucleus of the amygdala or to the dorsal medial prefrontal cortex.

Journal: The European journal of neuroscience 20050401

Title: In vivo quinolinic acid increases synaptosomal glutamate release in rats: reversal by guanosine.

Journal: Neurochemical research 20050401

Title: Divergent regulatory mechanisms governing BDNF mRNA expression in cerebral cortex and substantia nigra in response to striatal target ablation.

Journal: Experimental neurology 20050301

Title: Increase of adenine nucleotide hydrolysis in rat hippocampal slices after seizures induced by quinolinic acid.

Journal: Neurochemical research 20050301

Title: N-methyl-D-aspartate receptors are involved in the quinolinic acid, but not in the malonate pro-oxidative activity in vitro.

Journal: Neurochemical research 20050301

Title: Gestational and postnatal malnutrition affects sensitivity of young rats to picrotoxin and quinolinic acid and uptake of GABA by cortical and hippocampal slices.

Journal: Brain research. Developmental brain research 20050208

Title: Failure of caspase inhibition in the double-lesion rat model of striatonigral degeneration (multiple system atrophy).

Journal: Acta neuropathologica 20050201

Title: Minocycline in phenotypic models of Huntington's disease.

Journal: Neurobiology of disease 20050201

Title: Evaluation of [123I]IBZM pinhole SPECT for the detection of striatal dopamine D2 receptor availability in rats.

Journal: NeuroImage 20050201

Title: Brain-derived neurotrophic factor prevents changes in Bcl-2 family members and caspase-3 activation induced by excitotoxicity in the striatum.

Journal: Journal of neurochemistry 20050201

Title: Caspase-1 inhibitor Ac-YVAD-CHO attenuates quinolinic acid-induced increases in p53 and apoptosis in rat striatum.

Journal: Acta pharmacologica Sinica 20050201

Title: Krebs cycle intermediates modulate thiobarbituric acid reactive species (TBARS) production in rat brain in vitro.

Journal: Neurochemical research 20050201

Title: The pyridine ring of NAD is formed by a nonenzymatic pericyclic reaction.

Journal: Journal of the American Chemical Society 20050126

Title: The effect of orbital prefrontal cortex lesions on performance on a progressive ratio schedule: implications for models of inter-temporal choice.

Journal: Behavioural brain research 20050106

Title: Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons.

Journal: Glia 20050101

Title: Behavioral and anatomical effects of quinolinic acid in the striatum of the hemiparkinsonian rat.

Journal: Synapse (New York, N.Y.) 20050101

Title: Effects of chronic administered guanosine on behavioral parameters and brain glutamate uptake in rats.

Journal: Journal of neuroscience research 20050101

Title: Studying the immunosuppressive role of indoleamine 2,3-dioxygenase: tryptophan metabolites suppress rat allogeneic T-cell responses in vitro and in vivo.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050101

Title: Involvement of quinolinic acid in AIDS dementia complex.

Journal: Neurotoxicity research 20050101

Title: Identification of kynurenine pathway enzyme mRNAs and metabolites in human placenta: up-regulation by inflammatory stimuli and with clinical infection.

Journal: American journal of obstetrics and gynecology 20050101

Title: [The effects of lesions in the compact part of the substantia nigra on glutamate and GABA release in the pedunculopontine nucleus].

Journal: Revista de neurologia 20050101

Title: Intracerebroventricular guanine-based purines protect against seizures induced by quinolinic acid in mice.

Journal: Neurochemical research 20050101

Title: Training specificity, graft development and graft-mediated functional recovery in a rodent model of Huntington's disease.

Journal: Neuroscience 20050101

Title: Communication and re-use of chemical information in bioscience.

Journal: BMC bioinformatics 20050101

Title: Quinolinic acid promotes albumin deposition in Purkinje cell, astrocytic activation and lipid peroxidation in fetal brain.

Journal: Neuroscience 20050101

Title: Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex.

Journal: Journal of neuroinflammation 20050101

Title: Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: protective role of iron porphyrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III).

Journal: Neuroscience 20050101

Title: Analysis of Escherichia coli nicotinate mononucleotide adenylyltransferase mutants in vivo and in vitro.

Journal: BMC biochemistry 20050101

Title: A computational method to predict genetically encoded rare amino acids in proteins.

Journal: Genome biology 20050101

Title: Lesions of the dorsolateral striatum impair the acquisition of a simplified stimulus-response dependent conditional discrimination task.

Journal: Neuroscience 20050101

Title: Effects of some naturally occurring iron ion chelators on in vitro superoxide radical formation.

Journal: Biological trace element research 20050101

Title: Imaging D2-receptors in quinolinic acid lesioned rat striatum with high resolution pinhole SPECT.

Journal: Nuklearmedizin. Nuclear medicine 20050101

Title: Implications for the kynurenine pathway and quinolinic acid in amyotrophic lateral sclerosis.

Journal: Neuro-degenerative diseases 20050101

Title: Peroxynitrite decomposition catalyst, iron metalloporphyrin, reduces quinolinate-induced neurotoxicity in rats.

Journal: Synapse (New York, N.Y.) 20041215

Title: S-Allylcysteine, a garlic-derived antioxidant, ameliorates quinolinic acid-induced neurotoxicity and oxidative damage in rats.

Journal: Neurochemistry international 20041201

Title: Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease.

Journal: Neurobiology of disease 20041201

Title: Pharmacological manipulation of brain kynurenine metabolism.

Journal: Annals of the New York Academy of Sciences 20041201

Title: Neuroprotection by encapsulated choroid plexus in a rodent model of Huntington's disease.

Journal: Neuroreport 20041115

Title: Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression.

Journal: Biochimica et biophysica acta 20041108

Title: Multiple areas of magnetic bistability in the topological ferrimagnet [Co3(NC5H3(CO2)2-2,5)2(mu3-OH)2(OH2)2].

Journal: Journal of the American Chemical Society 20041020

Title: Charge-transfer matrixes as a tool to desorb intact labile molecules by matrix-assisted laser desorption/ionization. Use of 2,7-dimethoxynaphthalene in the ionization of polymetallic porphyrins.

Journal: Analytical chemistry 20041015

Title: Insulin growth factor-1 protects against excitotoxicity in the rat striatum.

Journal: Neuroreport 20041005

Title: Phthalate esters enhance quinolinate production by inhibiting alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD), a key enzyme of the tryptophan pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041001

Title: Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum.

Journal: Neurochemistry international 20041001

Title: Poloxamer 188 volumetrically decreases neuronal loss in the rat in a time-dependent manner.

Journal: Neurosurgery 20041001

Title: Assessment of the macrophage marker quinolinic acid in cerebrospinal fluid after pediatric traumatic brain injury: insight into the timing and severity of injury in child abuse.

Journal: Journal of neurotrauma 20040901

Title: Quinolinic acid promotes seizures and decreases glutamate uptake in young rats: reversal by orally administered guanosine.

Journal: Brain research 20040820

Title: Changes in quinolinic acid production and its related enzymes following D-galactosamine and lipopolysaccharide-induced hepatic injury.

Journal: Archives of biochemistry and biophysics 20040815

Title: Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy.

Journal: Intensive care medicine 20040801

Title: Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion.

Journal: Journal of neurochemistry 20040801

Title: Surfactant poloxamer 188-related decreases in inflammation and tissue damage after experimental brain injury in rats.

Journal: Journal of neurosurgery 20040801

Title: Human neural stem cell transplants improve motor function in a rat model of Huntington's disease.

Journal: The Journal of comparative neurology 20040719

Title: Progressive behavioural changes in the spatial open-field in the quinolinic acid rat model of Huntington's disease.

Journal: Behavioural brain research 20040709

Title: HIV in central nervous system and behavioral development: an HIV-2287 macaque model of AIDS.

Journal: AIDS (London, England) 20040702

Title: Overexpression, purification, and characterization of ATP-NAD kinase of Sphingomonas sp. A1.

Journal: Protein expression and purification 20040701

Title: Enhanced locomotor activity in rats with excitotoxic lesions of the entorhinal cortex, a neurodevelopmental animal model of schizophrenia: behavioral and in vivo microdialysis studies.

Journal: Neuroscience letters 20040701

Title: Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.

Journal: Journal of neuroscience research 20040701

Title: NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice.

Journal: Epilepsia 20040701

Title: Contributions of the anterior cingulate cortex and amygdala to pain- and fear-conditioned place avoidance in rats.

Journal: Pain 20040701

Title: The effects of nerve growth factor upon the neuropeptide content of the suprachiasmatic nucleus of rats withdrawn from ethanol are mediated by the nucleus basalis magnocellularis.

Journal: Journal of neurocytology 20040701

Title: Effects of hippocampus and medial caudate nucleus lesions on memory for direction information in rats.

Journal: Behavioral neuroscience 20040601

Title: Brain virus burden and indoleamine-2,3-dioxygenase expression during lentiviral infection of rhesus monkey are concomitantly lowered by 6-chloro-2',3'-dideoxyguanosine.

Journal: The European journal of neuroscience 20040601

Title: Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity.

Journal: Journal of neurochemistry 20040601

Title: Polyamines reduces lipid peroxidation induced by different pro-oxidant agents.

Journal: Brain research 20040522

Title: Effects of dietary di(2-ethylhexyl)phthalate, a putative endocrine disrupter, on enzyme activities involved in the metabolism of tryptophan to niacin in rats.

Journal: Biochimica et biophysica acta 20040503

Title: Evaluation of three quinoline-carboxamide derivatives as potential radioligands for the in vivo pet imaging of neurodegeneration.

Journal: Neurochemistry international 20040501

Title: Molecular biology of pyridine nucleotide and nicotine biosynthesis.

Journal: Frontiers in bioscience : a journal and virtual library 20040501

Title: CSF quinolinic acid levels are determined by local HIV infection: cross-sectional analysis and modelling of dynamics following antiretroviral therapy.

Journal: Brain : a journal of neurology 20040501

Title: Blockade of quinolinic acid-induced neurotoxicity by pyruvate is associated with inhibition of glial activation in a model of Huntington's disease.

Journal: Experimental neurology 20040501

Title: Characterization of striatal cultures with the effect of QUIN and NMDA.

Journal: Neuroscience research 20040501

Title: AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20040501

Title: Anticonvulsant effect of GMP depends on its conversion to guanosine.

Journal: Brain research 20040416

Title: Dorsal striatum and stimulus-response learning: lesions of the dorsolateral, but not dorsomedial, striatum impair acquisition of a simple discrimination task.

Journal: Behavioural brain research 20040402

Title: The effects of intracortical endothelin-1 injections on skilled forelimb use: implications for modelling recovery of function after stroke.

Journal: Behavioural brain research 20040402

Title: On-line process monitoring of water-soluble ions in pulp and paper machine waters by capillary electrophoresis.

Journal: Journal of chromatography. A 20040402

Title: Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease.

Journal: Molecular psychiatry 20040401

Title: Glutamatergic regulation of long-term grafts of fetal lateral ganglionic eminence in a rat model of Huntington's disease.

Journal: Neurobiology of disease 20040401

Title: Quinolinic acid lesions of the caudate putamen in the rat lead to a local increase of ciliary neurotrophic factor.

Journal: Journal of anatomy 20040401

Title: Age- and sex-dependent laterality of rat hippocampal cholinergic system in relation to animal models of neurodevelopmental and neurodegenerative disorders.

Journal: Neurochemical research 20040401

Title: Amelioration of behavioral deficits in a rat model of Huntington's disease by an excitotoxic lesion to the globus pallidus.

Journal: Experimental neurology 20040301

Title: Ascorbyl palmitate vesicles (Aspasomes): formation, characterization and applications.

Journal: International journal of pharmaceutics 20040301

Title: Association between inflammation and nigral neuronal damage following striatal excitotoxic lesion.

Journal: Brain research 20040213

Title: Inhibition of dopamine synthesis with alpha-methyl-p-tyrosine abolishes the enhancement of methamphetamine-induced extracellular dopamine levels in the amygdala of rats with excitotoxic lesions of the entorhinal cortex.

Journal: Neuroscience letters 20040206

Title: Evaluation with alpha-[11C]methyl-L-tryptophan positron emission tomography for reoperation after failed epilepsy surgery.

Journal: Epilepsia 20040201

Title: Excitotoxic degeneration of hypothalamic orexin neurons in slice culture.

Journal: Neurobiology of disease 20040201

Title: No nerve growth factor response to treatment with memantine in adult rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20040201

Title: The surfactant poloxamer-188 protects against glutamate toxicity in the rat brain.

Journal: Neuroreport 20040119

Title: Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment.

Journal: Neurology 20040113

Title: The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-alpha-induced depression.

Journal: Journal of psychiatry & neuroscience : JPN 20040101

Title: Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.

Journal: Bioscience, biotechnology, and biochemistry 20040101

Title: Environmental enrichment affects striatal graft morphology and functional recovery.

Journal: The European journal of neuroscience 20040101

Title: [Lesions in the pars compacta substantiae nigra and the subthalamic nucleus modify the density of muscarinic receptors in different nuclei of the basal ganglia].

Journal: Revista de neurologia 20040101

Title: Effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in mice.

Journal: Experimental animals 20040101

Title: Basal forebrain neurons modulate the synthesis and expression of neuropeptides in the rat suprachiasmatic nucleus.

Journal: Neuroscience 20040101

Title: A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases.

Journal: BMC bioinformatics 20040101

Title: Neuroprotective effects of encapsulated CNTF-producing cells in a rodent model of Huntington's disease are dependent on the proximity of the implant to the lesioned striatum.

Journal: Cell transplantation 20040101

Title: Transgenic nonhuman primates for neurodegenerative diseases.

Journal: Reproductive biology and endocrinology : RB&E 20040101

Title: Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease.

Journal: Neuroscience 20040101

Title: Basic science behind the catastrophic epilepsies.

Journal: Epilepsia 20040101

Title: Quinolinic acid induces NMDA receptor-mediated lipid peroxidation in rat brain microvessels.

Journal: Redox report : communications in free radical research 20040101

Title: Development of pathogenic concepts in glutaryl-CoA dehydrogenase deficiency: the challenge.

Journal: Journal of inherited metabolic disease 20040101

Title: Glutaric aciduria type I and kynurenine pathway metabolites: a modified hypothesis.

Journal: Journal of inherited metabolic disease 20040101

Title: Adenosine A2A receptor antagonism and neuroprotection: mechanisms, lights, and shadows.

Journal: Critical reviews in neurobiology 20040101

Title: Neurotoxic and neurobehavioral effects of kynurenines in adult insects.

Journal: Biochemical and biophysical research communications 20031226

Title: A beta 1-42 induces production of quinolinic acid by human macrophages and microglia.

Journal: Neuroreport 20031219

Title: Modulation of glutamate release and excitotoxicity by adenosine A2A receptors.

Journal: Neurology 20031209

Title: Hypothalamic digoxin, hemispheric chemical dominance, and oncogenesis: evidence from multiple myeloma.

Journal: The International journal of neuroscience 20031201

Title: Deficits induced by quinolinic acid lesion to the striatum in a position discrimination and reversal task are ameliorated by permanent and temporary lesion to the globus pallidus: a potential novel treatment in a rat model of Huntington's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20031201

Title: How to find 'missing' genes.

Journal: Chemistry & biology 20031201

Title: NAD biosynthesis: identification of the tryptophan to quinolinate pathway in bacteria.

Journal: Chemistry & biology 20031201

Title: Enkephalinergic striatal projection neurons become less affected by quinolinic acid than substance P-containing striatal projection neurons as rats age.

Journal: Experimental neurology 20031201

Title: Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference.

Journal: Brain research 20031114

Title: Expression of BDNF mRNA in substantia nigra is dependent on target integrity and independent of neuronal activation.

Journal: Journal of neurochemistry 20031101

Title: A hypothalamic digoxin-mediated model for autism.

Journal: The International journal of neuroscience 20031101

Title: Motor training effects on recovery of function after striatal lesions and striatal grafts.

Journal: Experimental neurology 20031101

Title: Modulation of stress-induced dopamine release by excitotoxic damage of the entorhinal cortex in the rat.

Journal: Brain research 20031031

Title: [(Th2F5)(NC7H5O4)2(H2O)][NO3]: an actinide-organic open framework.

Journal: Journal of the American Chemical Society 20031022

Title: Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents.

Journal: Experimental neurology 20031001

Title: c-fos and tyrosine hydroxylase expression after an excitotoxic lesion on the nigrostriatal system: a study on the effects of hypoxia used as a preconditioning stimulus.

Journal: Experimental neurology 20031001

Title: Neuroprotective effects of pyruvate in the quinolinic acid rat model of Huntington's disease.

Journal: Experimental neurology 20031001

Title: Reactions of the dirhenium(II) complex Re2Cl4(mu-dppm)2 with pyridinecarboxylic acids. Examples of bidentate O,O versus N,O coordination and tridentate O,N,O coordination and structural isomers that contain the pyridine-2,6-dicarboxylate ligand.

Journal: Inorganic chemistry 20030922

Title: Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria.

Journal: The Journal of infectious diseases 20030915

Title: A one-dimensional zigzag coordination polymer: catena-poly[[diaquapyridinenickel(II)]-mu-pyridine-2,3-dicarboxylato-kappa3N,O2:O3].

Journal: Acta crystallographica. Section C, Crystal structure communications 20030901

Title: Regioselective hydroxylation of quinolinic acid, lutidinic acid and isocinchomeronic acid by resting cells of pyridine dicarboxylic acid-degrading microorganisms.

Journal: Applied microbiology and biotechnology 20030901

Title: Co-localization of brain-derived neurotrophic factor (BDNF) and wild-type huntingtin in normal and quinolinic acid-lesioned rat brain.

Journal: The European journal of neuroscience 20030901

Title: Preserved sensitivity to outcome value after lesions of the basolateral amygdala.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030820

Title: Copper blocks quinolinic acid neurotoxicity in rats: contribution of antioxidant systems.

Journal: Free radical biology & medicine 20030815

Title: Synthesis, structure, and photoelectronic effects of a uranium-zinc-organic coordination polymer containing infinite metal oxide sheets.

Journal: Journal of the American Chemical Society 20030806

Title: Effects of undernutrition on glutamatergic parameters in rat brain.

Journal: Neurochemical research 20030801

Title: Quinolinate dehydrogenase and 6-hydroxyquinolinate decarboxylase involved in the conversion of quinolinic acid to 6-hydroxypicolinic acid by Alcaligenes sp. strain UK21.

Journal: Archives of microbiology 20030801

Title: Tryptophan and the immune response.

Journal: Immunology and cell biology 20030801

Title: Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspects.

Journal: Current medicinal chemistry 20030801

Title: Hypothalamic digoxin, hemispheric chemical dominance, and eating behavior.

Journal: The International journal of neuroscience 20030801

Title: A one-dimensional zigzag coordination polymer of diaqua(pyridine-2,3-dicarboxylato)cobalt(II).

Journal: Acta crystallographica. Section C, Crystal structure communications 20030801

Title: Adenosine A(2A) antagonism increases striatal glutamate outflow in the quinolinic acid rat model of Huntington's disease.

Journal: Brain research 20030725

Title: Chronically administered guanosine is anticonvulsant, amnesic and anxiolytic in mice.

Journal: Brain research 20030704

Title: Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: Behavioral/neurophysiological investigation of effects of combining a quinolinic acid entopeduncular lesion with a fetal mesencephalic tissue transplant in striatum of the 6-OHDA hemilesioned rat.

Journal: Synapse (New York, N.Y.) 20030701

Title: Crystallization and preliminary X-ray crystallographic analysis of quinolinate phosphoribosyltransferase of Helicobacter pylori.

Journal: Acta crystallographica. Section D, Biological crystallography 20030701

Title: Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: in vitro and in vivo studies.

Journal: Journal of neurochemistry 20030701

Title: The concept of cerebral chemical dominance.

Journal: The International journal of neuroscience 20030701

Title: Tryptophan metabolites and brain disorders.

Journal: Clinical chemistry and laboratory medicine 20030701

Title: GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults.

Journal: The Journal of comparative neurology 20030630

Title: Effects of lomefloxacin and norfloxacin on pancreatic beta-cell ATP-sensitive K(+) channels.

Journal: Life sciences 20030613

Title: Cytokines, neurophysiology, neuropsychology, and psychiatric symptoms.

Journal: Dialogues in clinical neuroscience 20030601

Title: Hypothalamic digoxin, cerebral chemical dominance and myalgic encephalomyelitis.

Journal: The International journal of neuroscience 20030501

Title: Hypothalamic digoxin, hemispheric dominance, and neurobiology of love and affection.

Journal: The International journal of neuroscience 20030501

Title: [Glutamate receptor dysfunction and psychosis-like behavior in an animal model].

Journal: Ceskoslovenska fysiologie 20030501

Title: Contribution of quinolinic acid in the development of anemia in renal insufficiency.

Journal: American journal of physiology. Renal physiology 20030401

Title: [Septic encephalopathy. Diagnosis und therapy].

Journal: Der Anaesthesist 20030401

Title: Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury.

Journal: Journal of molecular neuroscience : MN 20030401

Title: Hypothalamic digoxin-mediated model for Parkinson's disease.

Journal: The International journal of neuroscience 20030401

Title: Hypothalamic digoxin, hemispheric chemical dominance, and creativity.

Journal: The International journal of neuroscience 20030401

Title: Pre- or post-treatment with the mitochondrial uncoupler 2,4-dinitrophenol attenuates striatal quinolinate lesions.

Journal: Brain research 20030321

Title: Capillary electrophoretic separation of dicarboxylic acids in atmospheric aerosol particles.

Journal: Journal of chromatography. A 20030321

Title: Effects of adrenal medulla graft on recovery of GABAergic and dopaminergic neuron deficits in mice: behavioural, pharmacological and immunohistochemical study.

Journal: Behavioural brain research 20030318

Title: Quinolinic acid upregulates chemokine production and chemokine receptor expression in astrocytes.

Journal: Glia 20030301

Title: Hypothalamic digoxin, hemispheric chemical dominance, and Alzheimer's disease.

Journal: The International journal of neuroscience 20030301

Title: Hypothalamic digoxin, hemispheric chemical dominance, and spirituality.

Journal: The International journal of neuroscience 20030301

Title: Time-dependent relationship between the dorsal hippocampus and the prefrontal cortex in spatial memory.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215

Title: Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells.

Journal: The Journal of biological chemistry 20030207

Title: Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxygenase.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030201

Title: Hypothalamic digoxin--central role in conscious perception, neuroimmunoendocrine integration and coordination of cellular function--relation to hemispheric dominance.

Journal: Medical hypotheses 20030201

Title: Quetiapine produces a prolonged reversal of the sensorimotor gating-disruptive effects of basolateral amygdala lesions in rats.

Journal: Behavioral neuroscience 20030201

Title: Dipicolinic acid prevents the copper-dependent oxidation of low density lipoprotein.

Journal: The Journal of nutritional biochemistry 20030201

Title: The action of mexidol on the state of conditioned reflex activity after traumatic brain lesions.

Journal: Neuroscience and behavioral physiology 20030201

Title: Ciliary neurotrophic factor overexpression in neural progenitor cells (ST14A) increases proliferation, metabolic activity, and resistance to stress during differentiation.

Journal: Journal of neuroscience research 20030115

Title: alpha-[11C]-Methyl-L-tryptophan PET identifies the epileptogenic tuber and correlates with interictal spike frequency.

Journal: Epilepsy research 20030101

Title: Homocysteine-induced brain lipid peroxidation: effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition.

Journal: Neurotoxicity research 20030101

Title: Isoprenoid pathway related cascade in multiple myeloma.

Journal: Pathology oncology research : POR 20030101

Title: Comparative inhibition by substrate analogues 3-methoxy- and 3-hydroxydesaminokynurenine and an improved 3 step purification of recombinant human kynureninase.

Journal: BMC biochemistry 20030101

Title: Basolateral amygdala lesions impair both cue- and cocaine-induced reinstatement in animals trained on a discriminative stimulus task.

Journal: Neuroscience 20030101

Title: Cytokine-serotonin interaction through IDO: a neurodegeneration hypothesis of depression.

Journal: Medical hypotheses 20030101

Title: Hypothalamic digoxin-mediated model for trisomy 21.

Journal: Pediatric pathology & molecular medicine 20030101

Title: Quinolinic acid up-regulates chemokine production and chemokine receptor expression in astrocytes.

Journal: Advances in experimental medicine and biology 20030101

Title: Expression of the kynurenine pathway enzymes in human microglia and macrophages.

Journal: Advances in experimental medicine and biology 20030101

Title: Studies on the neuroprotective action of kynurenine mono-oxygenase inhibitors in post-ischemic brain damage.

Journal: Advances in experimental medicine and biology 20030101

Title: 3-Hydroxykynurenine and quinolinate: pathogenic synergism in early grade Huntington's disease?

Journal: Advances in experimental medicine and biology 20030101

Title: Accumulation of quinolinic acid with neuroinflammation: does it mean excitotoxicity?

Journal: Advances in experimental medicine and biology 20030101

Title: Quinolinic acid in the pathogenesis of Alzheimer's disease.

Journal: Advances in experimental medicine and biology 20030101

Title: Kynurenine metabolism in central nervous system in experimental chronic renal failure.

Journal: Advances in experimental medicine and biology 20030101

Title: Neurokynurenines--seizures or/and anxiety in children with epilepsy?

Journal: Advances in experimental medicine and biology 20030101

Title: Neuropeptide-containing cells in the cortex and striatum of mice with cerebral malaria.

Journal: Advances in experimental medicine and biology 20030101

Title: Increase in conversion of tryptophan to niacin in pregnant rats.

Journal: Advances in experimental medicine and biology 20030101

Title: Identification and expression of alpha cDNA encoding human 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD): a key enzyme for the tryptophan-niacine pathway and quinolinate hypothesis.

Journal: Advances in experimental medicine and biology 20030101

Title: Dietary linoleic acid suppresses gene expression of rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) and increases quinolinic acid in serum.

Journal: Advances in experimental medicine and biology 20030101

Title: ECNI GC-MS analysis of picolinic and quinolinic acids and their amides in human plasma, CSF, and brain tissue.

Journal: Advances in experimental medicine and biology 20030101

Title: Sustainable production of bioactive compounds from sponges: primmorphs as bioreactors.

Journal: Progress in molecular and subcellular biology 20030101

Title: The frontal cortex of the rat and visual attentional performance: dissociable functions of distinct medial prefrontal subregions.

Journal: Cerebral cortex (New York, N.Y. : 1991) 20021201

Title: Effects of quinolinic acid-induced lesions of the orbital prefrontal cortex on inter-temporal choice: a quantitative analysis.

Journal: Psychopharmacology 20021201

Title: Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions.

Journal: Experimental neurology 20021201

Title: Hypothalamic digoxin and regulation of body mass index.

Journal: Neurology India 20021201

Title: Identification of a toxic mechanism of the plasticizers, phtahlic acid esters, which are putative endocrine disrupters: time-dependent increase in quinolinic acid and its metabolites in rats fed di(2-ethylhexyl)phthalate.

Journal: Bioscience, biotechnology, and biochemistry 20021201

Title: Synthesis of the neurotoxin quinolinic acid in apoptotic tissue from Suberites domuncula: cell biological, molecular biological, and chemical analyses.

Journal: Marine biotechnology (New York, N.Y.) 20021201

Title: Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease.

Journal: Human gene therapy 20021101

Title: Adenosine A2A receptor imaging with [11C]KF18446 PET in the rat brain after quinolinic acid lesion: comparison with the dopamine receptor imaging.

Journal: Annals of nuclear medicine 20021101

Title: T cell apoptosis by tryptophan catabolism.

Journal: Cell death and differentiation 20021001

Title: Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Neopterin and quinolinic acid are surrogate measures of disease activity in the juvenile idiopathic inflammatory myopathies.

Journal: Clinical chemistry 20021001

Title: HIV-1-associated dementia: a metabolic encephalopathy perpetrated by virus-infected and immune-competent mononuclear phagocytes.

Journal: Journal of acquired immune deficiency syndromes (1999) 20021001

Title: Characterization of neurotransmitters and dopamine attenuation of inducible nitric oxide synthase in glioma cells.

Journal: Journal of neuroimmunology 20021001

Title: Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and 'quinolinate hypothesis'.

Journal: The Journal of biological chemistry 20020920

Title: Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures.

Journal: Journal of neurochemistry 20020901

Title: Drug targeting to the brain: transfer of picolinic acid along the olfactory pathways.

Journal: Journal of drug targeting 20020901

Title: SCH 58261 differentially influences quinolinic acid-induced effects in striatal and in hippocampal slices.

Journal: European journal of pharmacology 20020830

Title: Learning and memory in two different reward tasks in a radial arm maze in rats.

Journal: Behavioural brain research 20020821

Title: Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts.

Journal: American journal of veterinary research 20020801

Title: Cholinergic receptor activity after quinolinic acid caused cerebral injury in rats.

Journal: Chinese medical journal 20020801

Title: N-Methyl-D-aspartate receptor subtype-selectivity of homoquinolinate: an electrophysiological and radioligand binding study using both native and recombinant receptors.

Journal: Journal of neurochemistry 20020801

Title: Apoptosis of oligodendrocytes in secondary cultures from neonatal rat brains.

Journal: Neuroscience letters 20020719

Title: LC/MS analysis of NAD biosynthesis using stable isotope pyridine precursors.

Journal: Analytical biochemistry 20020715

Title: The pharmacological manipulation of glutamate receptors and neuroprotection.

Journal: European journal of pharmacology 20020705

Title: Habituation and cross-sensitization of stress-induced hypothalamic-pituitary-adrenal activity: effect of lesions in the paraventricular nucleus of the thalamus or bed nuclei of the stria terminalis.

Journal: Journal of neuroendocrinology 20020701

Title: Effects of systemic and central nervous system localized inflammation on the contributions of metabolic precursors to the L-kynurenine and quinolinic acid pools in brain.

Journal: Journal of neurochemistry 20020701

Title: [Microanalysis of tryptophan metabolites and suppressor factor of delayed-type hypersensitivity in mice].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020701

Title: Neurobiology of ammonia.

Journal: Progress in neurobiology 20020701

Title: Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer.

Journal: British journal of cancer 20020605

Title: Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes.

Journal: Neurochemistry international 20020601

Title: Synaptic localization of GABA(A) receptor subunits in the substantia nigra of the rat: effects of quinolinic acid lesions of the striatum.

Journal: The European journal of neuroscience 20020601

Title: Endogenous sodium-potassium ATPase inhibition related biochemical cascade in trisomy 21 and Huntington's disease: neural regulation of genomic function.

Journal: Neurology India 20020601

Title: Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.

Journal: Bioscience, biotechnology, and biochemistry 20020601

Title: Central role of hypothalamic digoxin in conscious perception, neuroimmunoendocrine integration, and coordination of cellular function: relation to hemispheric dominance.

Journal: The International journal of neuroscience 20020601

Title: Tryptophan metabolism in alcoholism.

Journal: Nutrition research reviews 20020601

Title: Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra.

Journal: Experimental neurology 20020501

Title: Maintenance of susceptibility to neurodegeneration following intrastriatal injections of quinolinic acid in a new transgenic mouse model of Huntington's disease.

Journal: Experimental neurology 20020501

Title: Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+.

Journal: Biochimica et biophysica acta 20020429

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Excitatory amino acids differentially regulate the expression of GDNF, neurturin, and their receptors in the adult rat striatum.

Journal: Experimental neurology 20020401

Title: Positron emission tomography and ex vivo and in vitro autoradiography studies on dopamine D2-like receptor degeneration in the quinolinic acid-lesioned rat striatum: comparison of [11C]raclopride, [11C]nemonapride and [11C]N-methylspiperone.

Journal: Nuclear medicine and biology 20020401

Title: Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain.

Journal: Neurochemical research 20020401

Title: Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS.

Journal: The European journal of neuroscience 20020401

Title: Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent.

Journal: Journal of neurochemistry 20020401

Title: Neuroprotective effects of lithium in cultured cells and animal models of diseases.

Journal: Bipolar disorders 20020401

Title: Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors.

Journal: The Journal of comparative neurology 20020318

Title: Hunting for excitement: NMDA receptors in Huntington's disease.

Journal: Neuron 20020314

Title: Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease.

Journal: Neuron 20020314

Title: Quinolinate phosphoribosyltransferase: kinetic mechanism for a type II PRTase.

Journal: Biochemistry 20020312

Title: Mechanisms of the protective effect of L-alanine to D-galactosamine-induced hepatocellular injury: comparative studies of L-alanine and pyruvate.

Journal: Biochemical and biophysical research communications 20020308

Title: The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria.

Journal: The Journal of infectious diseases 20020301

Title: Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure.

Journal: Nephron 20020301

Title: Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301

Title: Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease.

Journal: Journal of neurobiology 20020301

Title: Enhanced neuronal damage by co-administration of quinolinic acid and free radicals, and protection by adenosine A2A receptor antagonists.

Journal: British journal of pharmacology 20020301

Title: Effect of systemic L-DOPA administration on extracellular kynurenate levels in the rat striatum.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020301

Title: Endogenous neurotoxine-quinolinic acid is increased in renal allograft recipients.

Journal: Transplantation proceedings 20020301

Title: Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alterations produced by intra-striatal quinolinic acid administration in the rat.

Journal: Neuroscience letters 20020201

Title: Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry.

Journal: Analytical biochemistry 20020201

Title: Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice.

Journal: Journal of neuroscience research 20020201

Title: The effects of prelimbic and infralimbic lesions on working memory for visual objects in rats.

Journal: Neurobiology of learning and memory 20020101

Title: Identification of CD40 ligand in Alzheimer's disease and in animal models of Alzheimer's disease and brain injury.

Journal: Neurobiology of aging 20020101

Title: Function of the hypothalamo-pituitary-adrenocortical system during ontogenesis in rats with inherited stress-induced arterial hypertension.

Journal: Neuroscience and behavioral physiology 20020101

Title: The role of the ventrolateral nucleus of the thalamus in the switching of descending influences to motor activity in the rat.

Journal: Neuroscience and behavioral physiology 20020101

Title: Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease.

Journal: Neurosurgery 20020101

Title: Effects of nerve and fibroblast growth factors on the production of nitric oxide in experimental model of Huntington's disease.

Journal: Vojnosanitetski pregled 20020101

Title: Fetal striatal transplants restore electrophysiological sensitivity to dopamine in the lesioned striatum of rats with experimental Huntington's disease.

Journal: Journal of biomedical science 20020101

Title: Detailed localization of regulator of G protein signaling 2 messenger ribonucleic acid and protein in the rat brain.

Journal: Neuroscience 20020101

Title: Dynamic diversity of the tryptophan pathway in chlamydiae: reductive evolution and a novel operon for tryptophan recapture.

Journal: Genome biology 20020101

Title: Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus.

Journal: Physiological research 20020101

Title: Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease.

Journal: Redox report : communications in free radical research 20020101

Title: A 'single toxin-double lesion' rat model of striatonigral degeneration by intrastriatal 1-methyl-4-phenylpyridinium ion injection: a motor behavioural analysis.

Journal: Neuroscience 20020101

Title: Immunohistochemical visualization of newly formed quinolinate in the normal and excitotoxically lesioned rat striatum.

Journal: Experimental brain research 20011201

Title: TrkB and TrkC are differentially regulated by excitotoxicity during development of the basal ganglia.

Journal: Experimental neurology 20011201

Title: Metabolic changes in quinolinic acid-lesioned rat striatum detected non-invasively by in vivo (1)H NMR spectroscopy.

Journal: Journal of neuroscience research 20011201

Title: 17Beta-estradiol attenuates quinolinic acid insult in the rat hippocampus.

Journal: Metabolic brain disease 20011201

Title: Kynurenine and its metabolites in the rat with experimental renal insufficiency.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201

Title: IFN-beta1b induces kynurenine pathway metabolism in human macrophages: potential implications for multiple sclerosis treatment.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20011201

Title: Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome.

Journal: The European journal of neuroscience 20011201

Title: Hypothalamic digoxin mediated model for oncogenesis.

Journal: Journal of experimental & clinical cancer research : CR 20011201

Title: Lesions of the basolateral amygdala disrupt selective aspects of reinforcer representation in rats.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011115

Title: Localizing value of alpha-methyl-L-tryptophan PET in intractable epilepsy of neocortical origin.

Journal: Neurology 20011113

Title: Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages.

Journal: Journal of neuroimmunology 20011101

Title: Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine.

Journal: The European journal of neuroscience 20011101

Title: Resistance to NMDA toxicity correlates with appearance of nuclear inclusions, behavioural deficits and changes in calcium homeostasis in mice transgenic for exon 1 of the huntington gene.

Journal: The European journal of neuroscience 20011101

Title: The possible crucial role of iron accumulation combined with low tryptophan, zinc and manganese in carcinogenesis.

Journal: Medical hypotheses 20011101

Title: IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures.

Journal: Journal of inherited metabolic disease 20011101

Title: Differential expression of active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates following quinolinic acid excitotoxicity in the rat.

Journal: Brain research. Molecular brain research 20011019

Title: The role of the primate amygdala in conditioned reinforcement.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011001

Title: Increased cortical kynurenate content in schizophrenia.

Journal: Biological psychiatry 20011001

Title: Kynurenine production and catabolism in fetal sheep with embolized or nonembolized placentas.

Journal: American journal of obstetrics and gynecology 20011001

Title: Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.

Journal: Bioscience, biotechnology, and biochemistry 20011001

Title: Effect of orally administered guanosine on seizures and death induced by glutamatergic agents.

Journal: Brain research 20010907

Title: Basolateral amygdala lesions disrupt latent inhibitionin rats.

Journal: Brain research bulletin 20010901

Title: In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum.

Journal: Neuroreport 20010828

Title: The role of rat dorsomedial prefrontal cortex in working memory for egocentric responses.

Journal: Neuroscience letters 20010810

Title: Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection.

Journal: Journal of neurochemistry 20010801

Title: Glyoxylate determination in rat urine by capillary electrophoresis.

Journal: International journal of urology : official journal of the Japanese Urological Association 20010801

Title: Role of the medial and lateral caudate-putamen in mediating an auditory conditional response association.

Journal: Neurobiology of learning and memory 20010701

Title: Differential effects of unilateral striatal and nigrostriatal lesions on grip strength, skilled paw reaching and drug-induced rotation in the rat.

Journal: Brain research bulletin 20010701

Title: Kynurenines in the CNS: from endogenous obscurity to therapeutic importance.

Journal: Progress in neurobiology 20010601

Title: Role of the striatum and nucleus accumbens in paced copulatory behavior in the female rat.

Journal: Behavioural brain research 20010601

Title: Time course of glial proliferation and glial apoptosis following excitotoxic CNS injury.

Journal: Brain research 20010601

Title: Similarities and differences in the neuronal death processes activated by 3OH-kynurenine and quinolinic acid.

Journal: Journal of neurochemistry 20010601

Title: Expression of cyclin-dependent kinase 5 and its activator p35 in models of induced apoptotic death in neurons of the substantia nigra in vivo.

Journal: Journal of neurochemistry 20010601

Title: Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease.

Journal: Neurobiology of disease 20010601

Title: Quinolinic acid accumulation during neuroinflammation. Does it imply excitotoxicity?

Journal: Annals of the New York Academy of Sciences 20010601

Title: Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.

Journal: Bioscience, biotechnology, and biochemistry 20010601

Title: [Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010601

Title: Excitotoxic injury stimulates pro-drug-induced 7-chlorokynurenate formation in the rat striatum in vivo.

Journal: Neuroscience letters 20010525

Title: Rolipram reduces excitotoxic neuronal damage.

Journal: Neuroreport 20010525

Title: Prenatal exposure to methyl mercury in rats: focus on changes in kynurenine pathway.

Journal: Brain research bulletin 20010515

Title: Elevated cerebrospinal fluid quinolinic acid levels are associated with region-specific cerebral volume loss in HIV infection.

Journal: Brain : a journal of neurology 20010501

Title: Dissociable contributions of the orbitofrontal and lateral prefrontal cortex of the marmoset to performance on a detour reaching task.

Journal: The European journal of neuroscience 20010501

Title: Quinolinic acid-iron(ii) complexes: slow autoxidation, but enhanced hydroxyl radical production in the Fenton reaction.

Journal: Free radical research 20010501

Title: Changes in kynurenic, anthranilic, and quinolinic acid concentrations in rat brain tissue during development.

Journal: Neurochemical research 20010501

Title: Prostaglandin A(1) protects striatal neurons against excitotoxic injury in rat striatum.

Journal: The Journal of pharmacology and experimental therapeutics 20010401

Title: Kynurenic acid antagonists and kynurenine pathway inhibitors.

Journal: Expert opinion on investigational drugs 20010401

Title: Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease.

Journal: Neurochemical research 20010401

Title: Oligodendrocyte killing by quinolinic acid in vitro.

Journal: Brain research 20010330

Title: Quinolinic acid induces oxidative stress in rat brain synaptosomes.

Journal: Neuroreport 20010326

Title: CPI-1189 attenuates effects of suspected neurotoxins associated with AIDS dementia: a possible role for ERK activation.

Journal: Brain research 20010302

Title: Neuroprotection by estrogen via extracellular signal-regulated kinase against quinolinic acid-induced cell death in the rat hippocampus.

Journal: The European journal of neuroscience 20010201

Title: Kynurenic acid influences the respiratory parameters of rat heart mitochondria.

Journal: Pharmacology 20010201

Title: The effects of excitotoxic lesions of the nucleus accumbens core or shell regions on intravenous heroin self-administration in rats.

Journal: Psychopharmacology 20010201

Title: The effects of nucleus accumbens core and shell lesions on intravenous heroin self-administration and the acquisition of drug-seeking behaviour under a second-order schedule of heroin reinforcement.

Journal: Psychopharmacology 20010201

Title: A sensitive and reliable method for the detection of lipid peroxidation in biological tissues.

Journal: The Journal of pharmacy and pharmacology 20010201

Title: Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat.

Journal: Journal of neurovirology 20010201

Title: Endogenous neurotoxins from tryptophan.

Journal: Toxicon : official journal of the International Society on Toxinology 20010101

Title: The nicotinamide biosynthetic pathway is a by-product of the RNA world.

Journal: Journal of molecular evolution 20010101

Title: N-methyl-D-aspartate receptors mediating hippocampal noradrenaline and striatal dopamine release display differential sensitivity to quinolinic acid, the HIV-1 envelope protein gp120, external pH and protein kinase C inhibition.

Journal: Journal of neurochemistry 20010101

Title: Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101

Title: The biosynthesis of nicotinamide adenine dinucleotides in bacteria.

Journal: Vitamins and hormones 20010101

Title: Simultaneous intrastriatal 6-hydroxydopamine and quinolinic acid injection: a model of early-stage striatonigral degeneration.

Journal: Experimental neurology 20010101

Title: The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity.

Journal: Experimental neurology 20010101

Title: Regional changes in kynurenic acid, quinolinic acid, and glial fibrillary acidic protein concentrations in the fetal sheep brain after experimentally induced placental insufficiency.

Journal: American journal of obstetrics and gynecology 20010101

Title: Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis.

Journal: Neuroscience 20010101

Title: Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme.

Journal: BMC biochemistry 20010101

Title: Effects of red nucleus ablation and exogenous neurotrophin-3 on corticospinal axon terminal distribution in the adult rat.

Journal: Neuroscience 20010101

Title: A hypothalamic digoxin mediated model for conscious and subliminal perception.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101

Title: The role of cerebral oedema in the pathogenesis of cerebral malaria.

Journal: Redox report : communications in free radical research 20010101

Title: Oxidative damage and metabolic dysfunction in experimental Huntington's disease: selective vulnerability of the striatum and hippocampus.

Journal: Vojnosanitetski pregled 20010101

Title: Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease.

Journal: Neuroscience 20010101

Title: Hypothalamic digoxin, hemispheric dominance and the acquired immunodeficiency syndrome.

Journal: Neuroimmunomodulation 20010101

Title: Accumulation of toxic products degradation of kynurenine in hemodialyzed patients.

Journal: International urology and nephrology 20010101

Title: (R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 19990601

Title: Preclinical characterization of MDL 27,192 as a potential broad spectrum anticonvulsant agent with neuroprotective properties.

Journal: Epilepsy research 19970401

Title: Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease.

Journal: Neuroscience 19950201

Title: Lesions of the entopeduncular nucleus and the subthalamic nucleus reduce dopamine receptor antagonist-induced catalepsy in the rat.

Journal: Behavioural brain research 19940530

Title: Nicotine potentiation of haloperidol-induced catalepsy: striatal mechanisms.

Journal: Pharmacology, biochemistry, and behavior 19931001

Title: Neural grafts and pharmacological intervention in a model of Huntington's disease.

Journal: Brain research bulletin 19900901

Title: MK801 prevents quinolinic acid-induced behavioral deficits and neurotoxicity in the striatum.

Journal: Brain research bulletin 19900301

Title: Dextromethorphan does not protect against quinolinic acid neurotoxicity in rat striatum.

Journal: Neuroscience letters 19881219

Title: Episodic barrel rotations induced by intrastriatal injection of quinolinic acid in rats. Inhibition by anticonvulsants.

Journal: Pharmacology, biochemistry, and behavior 19880901

Title: Norepinephrine modulates seizures induced by quinolinic acid in rats: selective and distinct roles of alpha-adrenoceptor subtypes.

Journal: European journal of pharmacology 19870626

Title: Antagonism of kynurenine-induced seizures by picolinic, kynurenic and xanthurenic acids.

Journal: Journal of neural transmission 19830101

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Tags:89-00-9 Molecular Formula|89-00-9 MDL|89-00-9 SMILES|89-00-9 Quinolinic acid |Heterocyclic_Building_Blocks |Organic_Building_Blocks