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89-86-1,MFCD00002451
Catalog No.:AA003FQE

89-86-1 | 2,4-Dihydroxybenzoic acid

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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003FQE
Chemical Name:
2,4-Dihydroxybenzoic acid
CAS Number:
89-86-1
Molecular Formula:
C7H6O4
Molecular Weight:
154.1201
MDL Number:
MFCD00002451
SMILES:
Oc1ccc(c(c1)O)C(=O)O
FEMA Number:
3798
Properties
Properties
 
BP:
414.833 °C at 760 mmHg  
Form:
Solid  
MP:
225-227 °C  
Refractive Index:
1.6710 (estimate)  
Solubility:
8g/l  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
157  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
1  
XLogP3:
1.6  

Literature

Title: Degradation of 2,4-dihydroxibenzoic acid by vacuum UV process in aqueous solution: kinetic, identification of intermediates and reaction pathway.

Journal: Journal of hazardous materials 20121030

Title: Synthesis and characterization of molecules containing thiazole and oxazole moieties and study of ESIPT phenomenon.

Journal: Journal of fluorescence 20120901

Title: Rietveld refinement of the cocrystal 2,4-dihydroxybenzoic acid-N'-(propan-2-ylidene)nicotinohydrazide (1/1).

Journal: Acta crystallographica. Section C, Crystal structure communications 20120901

Title: Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.

Journal: The Journal of biological chemistry 20120706

Title: Polyphenols in red wine aged in acacia (Robinia pseudoacacia) and oak (Quercus petraea) wood barrels.

Journal: Analytica chimica acta 20120630

Title: The complexity of hydration of phloroglucinol: a comprehensive structural and thermodynamic characterization.

Journal: The journal of physical chemistry. B 20120405

Title: Electrochemical and spectroscopic investigations of isoniazide and its analogs with ds.DNA at physiological pH: evaluation of biological activities.

Journal: European journal of medicinal chemistry 20120101

Title: Three new phenolic compounds from the lichen Thamnolia vermicularis and their antiproliferative effects in prostate cancer cells.

Journal: Planta medica 20111201

Title: Determination of zearalenone and its metabolites in endometrial cancer by coupled separation techniques.

Journal: Analytical and bioanalytical chemistry 20111001

Title: Direct screening of G-quadruplex ligands from Kalopanax septemlobus (Thunb.) Koidz extract by high performance liquid chromatography.

Journal: Journal of chromatography. A 20110916

Title: Specific ion effects on adsorption at the solid/electrolyte interface: a probe into the concentration limit.

Journal: Langmuir : the ACS journal of surfaces and colloids 20110719

Title: Benzyl benzoates: New phlorizin analogs as mushroom tyrosinase inhibitors.

Journal: Bioorganic & medicinal chemistry 20110201

Title: Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

Journal: Journal of medicinal chemistry 20110127

Title: Analysis of phenolic compounds in health care products by low-pressure liquid-chromatography with monolithic column and chemiluminescent detection.

Journal: Luminescence : the journal of biological and chemical luminescence 20110101

Title: Effect of subinhibitory concentrations of plant-derived molecules in increasing the sensitivity of multidrug-resistant Salmonella enterica serovar Typhimurium DT104 to antibiotics.

Journal: Foodborne pathogens and disease 20101001

Title: Molecular cloning and characterization of a novel tomato xylosyltransferase specific for gentisic acid.

Journal: Journal of experimental botany 20101001

Title: Bis(μ-2,4-dihy-droxy-benzoato-κO:O')bis-[aqua-(2,4-dihy-droxy-benzoato-κO)(1,10-phenanthroline-κN,N')cadmium(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20100701

Title: beta-Resorcylic acid lactones from a Paecilomyces fungus.

Journal: Journal of natural products 20100528

Title: Bis(μ-4-chloro-2-oxidobenzoato)bis-[(1,10-phenanthroline)copper(II)] dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Hyperglycemia impairs proteasome function by methylglyoxal.

Journal: Diabetes 20100301

Title: Kinetics and Mechanisms of the Chromium(III) Reactions with 2,4- and 2,5-Dihydroxybenzoic Acids in Weak Acidic Aqueous Solutions.

Journal: Bioinorganic chemistry and applications 20100101

Title: Molecular modeling of peroxidase and polyphenol oxidase: substrate specificity and active site comparison.

Journal: International journal of molecular sciences 20100101

Title: A study of oleic acid and 2,4-DHB acid aerosols using an IR-VUV-ITMS: insights into the strengths and weaknesses of the technique.

Journal: Physical chemistry chemical physics : PCCP 20090928

Title: Formation of bromoform in irradiated titanium dioxide suspensions with varying photocatalyst, dissolved organic carbon and bromide concentrations.

Journal: Water research 20090901

Title: Compatibility study of trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (TNAD) with some energetic components and inert materials.

Journal: Journal of hazardous materials 20081230

Title: Solid-state changes in ligand-to-metal charge-transfer spectra of (NH3)5Ru(III)(2,4-dihydroxybenzoate) and (NH3)5Ru(III)(xanthine) chromophores.

Journal: Inorganic chemistry 20081103

Title: Effect of the template and functional monomer on the textural properties of molecularly imprinted polymers.

Journal: Biosensors & bioelectronics 20080915

Title: Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080901

Title: Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acids.

Journal: Bioorganic & medicinal chemistry 20080415

Title: Formation of brominated products in irradiated titanium dioxide suspensions containing bromide and dissolved organic carbon.

Journal: Water research 20080301

Title: DFT and ab initio study of structure of dyes derived from 2-hydroxy and 2,4-dihydroxy benzoic acids.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080201

Title: 2,4-Dihydr-oxy-N'-(4-methoxy-benzyl-idene)benzohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: Inter-individual variability in esterases in human liver.

Journal: Biochemical pharmacology 20070915

Title: Iron-doped carbon aerogels: novel porous substrates for direct growth of carbon nanotubes.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070424

Title: Structure and hydrogen bonding in 2,4-dihydroxybenzoic acid at 90, 100, 110 and 150 K; a theoretical and single-crystal X-ray diffraction study.

Journal: Acta crystallographica. Section B, Structural science 20070401

Title: 3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

Journal: Bioorganic & medicinal chemistry 20070301

Title: Chemistry and biology of resorcylic acid lactones.

Journal: Chemical communications (Cambridge, England) 20070107

Title: [Inhibitory effects of Lantana camera and its contained phenolic compounds in Eichhornia crassipes growth].

Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20060901

Title: Molecularly imprinted polymers with a streamlined mimic for zearalenone analysis.

Journal: Journal of chromatography. A 20060526

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Determination of resorcylic acid lactones in biological samples by GC-MS. Discrimination between illegal use and contamination with fusarium toxins.

Journal: Analytical and bioanalytical chemistry 20060301

Title: Determination of aerobic-anaerobic metabolism-related compounds in a Chaoborus flavicans population by infusion ion trap mass spectrometry of extracts of individual larvae.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Comparison of highly-fluorinated chloroformates as direct aqueous sample derivatizing agents for hydrophilic analytes and drinking-water disinfection by-products.

Journal: Journal of the American Society for Mass Spectrometry 20050601

Title: Formation of graphitic structures in cobalt- and nickel-doped carbon aerogels.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050329

Title: FT-IR and NMR spectroscopic studies of salicylic acid derivatives. II. Comparison of 2-hydroxy- and 2,4- and 2,5-dihydroxy derivatives.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20040901

Title: Antibacterial activities of naturally occurring compounds against antibiotic-resistant Bacillus cereus vegetative cells and spores, Escherichia coli, and Staphylococcus aureus.

Journal: Journal of food protection 20040801

Title: Beta-thujaplicin: new quantitative CZE method and adsorption to goethite.

Journal: Journal of agricultural and food chemistry 20040324

Title: Influence of amide linkages on acidity determinations of humic substances Testing with model-mixtures.

Journal: Talanta 20040310

Title: Improvements in ion signal reproducibility obtained using a homogeneous laser beam for on-line laser desorption/ionization of single particles.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Altered balance of half-reactions in p-hydroxybenzoate hydroxylase caused by substituting the 2'-carbon of FAD with fluorine.

Journal: The Journal of biological chemistry 20030620

Title: Kinetic model for phenolic compound oxidation by Fenton's reagent.

Journal: Chemosphere 20011001

Title: Degradation products of cyanidin glycosides from tart cherries and their bioactivities.

Journal: Journal of agricultural and food chemistry 20011001

Title: Specific inhibition of a family 1A dihydroorotate dehydrogenase by benzoate pyrimidine analogues.

Journal: Journal of medicinal chemistry 20010830

Title: Determination of calcium dobesilate in human plasma using ion-pairing extraction and high-performance liquid chromatography.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010505

Title: Complexation equilibria and spectrophotometric determination of iron(III) with resorcylic acid.

Journal: Journal of AOAC International 20010101

Title: Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring.

Journal: Biochemistry 19940823

Title: Seeram NP, et al. Degradation products of cyanidin glycosides from tart cherries and their bioactivities. J Agric Food Chem. 2001 Oct;49(10):4924-9.

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Tags:89-86-1 Molecular Formula|89-86-1 MDL|89-86-1 SMILES|89-86-1 2,4-Dihydroxybenzoic acid |Organic_Building_Blocks