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899431-18-6,MFCD17215929
Catalog No.:AA00GT96

899431-18-6 | A 438079 hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$128.00   $89.00
- +
10mg
≥98%
in stock  
$240.00   $168.00
- +
25mg
≥98%
in stock  
$472.00   $330.00
- +
50mg
95%
in stock  
$729.00   $510.00
- +
100mg
95%
in stock  
$1,241.00   $869.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GT96
Chemical Name:
A 438079 hydrochloride
CAS Number:
899431-18-6
Molecular Formula:
C13H10Cl3N5
Molecular Weight:
342.6110
MDL Number:
MFCD17215929
SMILES:
C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl
Properties
Computed Properties
 
Complexity:
319  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  

Literature

Title: McGaraughty S, et al. P2X7-related modulation of pathological nociception in rats. Neuroscience. 2007 Jun 8;146(4):1817-28.

Title: Mesuret G, et al. CNS Neurosci Ther. 2014 Jun;20(6):556-64.

Title: Marcellino D, et al. On the role of P2X(7) receptors in dopamine nerve cell degeneration in a rat model of Parkinson's disease: studies with the P2X(7) receptor antagonist A-438079. J Neural Transm (Vienna). 2010 Jun;117(6):681-7.

Title: Martins JP, et al. The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice. Br J Pharmacol. 2012 Jan;165(1):183-96.

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SDS
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Tags:899431-18-6 Molecular Formula|899431-18-6 MDL|899431-18-6 SMILES|899431-18-6 A 438079 hydrochloride