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90349-23-8,MFCD01051014
Catalog No.:AA00GSQM

90349-23-8 | 5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$33.00   $23.00
- +
1g
98%
in stock  
$41.00   $29.00
- +
5g
97%
in stock  
$150.00   $105.00
- +
10g
98%
in stock  
$180.00   $126.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00GSQM
Chemical Name:
5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
90349-23-8
Molecular Formula:
C9H9N3O2
Molecular Weight:
191.1867
MDL Number:
MFCD01051014
SMILES:
Cc1cc(C)n2c(n1)c(cn2)C(=O)O
Properties
Computed Properties
 
Complexity:
246  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.7  

Upstream Synthesis Route

[1]MonatsheftefurChemie,2016,vol.147,#12,p.2221-2234

[2]Patent:WO2016/73895,2016,A1,.Locationinpatent:Paragraph00220

[3]Patent:WO2012/78855,2012,A1,.Locationinpatent:Page/Pagecolumn17

[4]JournalofMedicinalChemistry,2012,vol.55,#12,p.5734-5748

[5]JournalofHeterocyclicChemistry,2018,vol.55,#1,p.214-225

[1]JournalofMedicinalChemistry,2017,vol.60,#18,p.7658-7676

[1]Patent:WO2012/78855,2012,A1,

[2]JournalofMedicinalChemistry,2012,vol.55,#12,p.5734-5748

[3]Patent:WO2016/73895,2016,A1,

Downstream Synthesis Route
90349-23-8   
5,7-dimethyl-pyrazolo1,5-apyrimidine-3-carboxylicacid1-methyl-2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl-amide 

[1]Patent:US2007/37974,2007,A1.Locationinpatent:Page/Pagecolumn23

N-((1s,4s)-4-aminocyclohexyl)-5-fluoro-2-(4'-((4-(2-(isopropylamino)-2-oxoethyl)piperazin-1-yl)methyl)-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamidehydrochloride 
  90349-23-8   
N-((1s,4s)-4-(5-fluoro-2-(4'-((4-(2-(isopropylamino)-2-oxoethyl)piperazin-1-yl)methyl)-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5,7-dimethylpyrazolo1,5-apyrimidine-3-carboxamide 

[1]Patent:WO2009/144494,2009,A1.Locationinpatent:Page/Pagecolumn272

N-((1s,4s)-4-aminocyclohexyl)-5-fluoro-2-(4'-((4-(2-hydroxyethyl)-1,4-diazepan-1-yl)methyl)-2'-(((S)-3-methylmorpholino)methyl)biphenyl-3-yloxy)nicotinamidehydrochloride 
  90349-23-8   
N-((1s,4s)-4-(5-fluoro-2-(4'-((4-(2-hydroxyethyl)-1,4-diazepan-1-yl)methyl)-2'-(((S)-3-methylmorpholino)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5,7-dimethylpyrazolo1,5-apyrimidine-2-carboxamide 

[1]Patent:WO2009/144494,2009,A1.Locationinpatent:Page/Pagecolumn274-275

N-((1s,4s)-4-aminocyclohexyl)-5-fluoro-2-(4'-((4-(2-hydroxyethyl)-1,4-diazepan-1-yl)methyl)-2'-(thiomorpholinomethyl)biphenyl-3-yloxy)nicotinamide 
  90349-23-8   
N-((1s,4s)-4-(5-fluoro-2-(4'-((4-(2-hydroxyethyl)-1,4-diazepan-1-yl)methyl)-2'-(thiomorpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5,7-dimethylpyrazolo1,5-apyrimidine-3-carboxamide 

[1]Patent:WO2009/144494,2009,A1.Locationinpatent:Page/Pagecolumn279

[1]Patent:WO2012/78855,2012,A1.Locationinpatent:Page/Pagecolumn17-18

[2]JournalofMedicinalChemistry,2012,vol.55,p.5734-5748

Literature

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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SDS
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Tags:90349-23-8 Molecular Formula|90349-23-8 MDL|90349-23-8 SMILES|90349-23-8 5,7-Dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid