Title: The promotion on cell growth of androgen-dependent prostate cancer by antimony via mimicking androgen activity.
Journal: Toxicology letters 20180515
Title: Assessment of endocrine disruption and oxidative potential of bisphenol-A, triclosan, nonylphenol, diethylhexyl phthalate, galaxolide, and carbamazepine, common contaminants of municipal biosolids.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180401
Title: Iminoenamine based novel androgen receptor antagonist exhibited anti-prostate cancer activity in androgen independent prostate cancer cells through inhibition of AKT pathway.
Journal: Chemico-biological interactions 20170925
Title: Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.
Journal: Chemical research in toxicology 20170515
Title: 6-(3,4-Dihydro-1H-isoquinoline-2-yl)-N-(6-methoxypyridine-2-yl) nicotinamide-26 (DIMN-26) decreases cell proliferation by induction of apoptosis and downregulation of androgen receptor signaling in human prostate cancer cells.
Journal: Chemico-biological interactions 20161225
Title: TBECH, 1,2-dibromo-4-(1,2 dibromoethyl) cyclohexane, alters androgen receptor regulation in response to mutations associated with prostate cancer.
Journal: Toxicology and applied pharmacology 20160915
Title: Sensitization of androgen refractory prostate cancer cells to anti-androgens through re-expression of epigenetically repressed androgen receptor - Synergistic action of quercetin and curcumin.
Journal: Molecular and cellular endocrinology 20160815
Title: Development and pre-validation of an in vitro transactivation assay for detection of (anti)androgenic potential compounds using 22Rv1/MMTV cells.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20160401
Title: The brominated flame retardants TBP-AE and TBP-DBPE antagonize the chicken androgen receptor and act as potential endocrine disrupters in chicken LMH cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20151201
Title: Androgen receptor functions as a negative transcriptional regulator of DEPTOR, mTOR inhibitor.
Journal: The Journal of toxicological sciences 20151201
Title: Testotoxicosis: Report of Two Cases, One with a Novel Mutation in LHCGR Gene.
Journal: Journal of clinical research in pediatric endocrinology 20150901
Title: Effects of treatment with androgen receptor ligands on microRNA expression of prostate cancer cells.
Journal: Toxicology 20150703
Title: Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells.
Journal: The Journal of biological chemistry 20150619
Title: Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601
Title: Identification of a group of brominated flame retardants as novel androgen receptor antagonists and potential neuronal and endocrine disrupters.
Journal: Environment international 20150101
Title: Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.
Journal: Nature 20140612
Title: Targeted androgen pathway suppression in localized prostate cancer: a pilot study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20140120
Title: Targeting cell cycle and hormone receptor pathways in cancer.
Journal: Oncogene 20131128
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Bisphenol A affects androgen receptor function via multiple mechanisms.
Journal: Chemico-biological interactions 20130525
Title: Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor.
Journal: Chemico-biological interactions 20130525
Title: Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130101
Title: Androgen signaling promotes translation of TMEFF2 in prostate cancer cells via phosphorylation of the α subunit of the translation initiation factor 2.
Journal: PloS one 20130101
Title: Development and validation of a highly sensitive LC-MS/MS-ESI method for the determination of bicalutamide in mouse plasma: application to a pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20121201
Title: Biopsy Gleason score and the duration of testosterone suppression among men treated with external beam radiation and 6 months of combined androgen blockade.
Journal: BJU international 20121101
Title: Exploring the cyclooxygenase 2 (COX2)/15d-Δ(12,14)PGJ(2) system in hamster Sertoli cells: regulation by FSH/testosterone and relevance to glucose uptake.
Journal: General and comparative endocrinology 20121101
Title: 3,3'-Disubstituted bipolar biphenyls as inhibitors of nuclear receptor coactivator binding.
Journal: Bioorganic & medicinal chemistry letters 20121101
Title: Images in clinical medicine. Gynecomastia induced by prostate-cancer treatment.
Journal: The New England journal of medicine 20121011
Title: Prostate-specific antigen response to deferred combined androgen blockade therapy using bicalutamide predicts survival after subsequent oestrogen and docetaxel therapies in patients with castration-resistant prostate cancer.
Journal: BJU international 20121001
Title: Editorial comment. Prostate-specific antigen response to deferred combined androgen blockade therapy using bicalutamide predicts survival after subsequent oestrogen and docetaxel therapies in patients with castration-resistant prostate cancer.
Journal: BJU international 20121001
Title: SGEF is overexpressed in prostate cancer and contributes to prostate cancer progression.
Journal: Oncology reports 20121001
Title: Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells.
Journal: International journal of cancer 20120915
Title: Autophagy regulates lipolysis and cell survival through lipid droplet degradation in androgen-sensitive prostate cancer cells.
Journal: The Prostate 20120915
Title: A randomized trial comparing tamoxifen therapy vs. tamoxifen prophylaxis in bicalutamide-induced gynecomastia.
Journal: Clinical genitourinary cancer 20120901
Title: A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer.
Journal: Investigational new drugs 20120801
Title: Upfront androgen deprivation therapy with salvage radiation may improve biochemical outcomes in prostate cancer patients with post-prostatectomy rising PSA.
Journal: International journal of radiation oncology, biology, physics 20120801
Title: Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer.
Journal: Pharmaceutical research 20120801
Title: Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models.
Journal: International journal of oncology 20120801
Title: [Prostate carcinoma with squamous differentiation after combination endocrine therapy: a case report].
Journal: Hinyokika kiyo. Acta urologica Japonica 20120801
Title: Elevation of c-FLIP in castrate-resistant prostate cancer antagonizes therapeutic response to androgen receptor-targeted therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120715
Title: A competitive inhibitor that reduces recruitment of androgen receptor to androgen-responsive genes.
Journal: The Journal of biological chemistry 20120706
Title: Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling.
Journal: Journal of natural medicines 20120701
Title: Phase I trial of tremelimumab in combination with short-term androgen deprivation in patients with PSA-recurrent prostate cancer.
Journal: Cancer immunology, immunotherapy : CII 20120701
Title: Chemical castration and anti-androgens induce differential gene expression in prostate cancer.
Journal: The Journal of pathology 20120701
Title: Antitumor agents 290. Design, synthesis, and biological evaluation of new LNCaP and PC-3 cytotoxic curcumin analogs conjugated with anti-androgens.
Journal: Bioorganic & medicinal chemistry 20120701
Title: Effects of the anti-androgen, bicalutamide, in a reduced life-cycle study with the fathead minnow (Pimephales promelas).
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120615
Title: Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.
Journal: The Prostate 20120601
Title: Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling.
Journal: Pharmaceutical research 20120601
Title: Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells.
Journal: Cancer science 20120601
Title: The long-term results with delayed-combined androgen blockade therapy in local or locally advanced prostate cancer.
Journal: Japanese journal of clinical oncology 20120601
Title: P53 and the proteasome regulate androgen receptor activity.
Journal: Cancer biology & therapy 20120501
Title: Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.
Journal: Cancer research 20120501
Title: Estrogen receptor-α and sex steroid hormones regulate Toll-like receptor-9 expression and invasive function in human breast cancer cells.
Journal: Breast cancer research and treatment 20120401
Title: [Impact of androgen deprivation on the lipid profile and atherogenic risk in prostate cancer patients].
Journal: Actas urologicas espanolas 20120401
Title: Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20120401
Title: Development and validation of stability-indicating HPLC and UPLC methods for the determination of bicalutamide.
Journal: Journal of chromatographic science 20120401
Title: Phase II study of long-term androgen suppression with bevacizumab and intensity-modulated radiation therapy (IMRT) in high-risk prostate cancer.
Journal: International journal of radiation oncology, biology, physics 20120315
Title: ARN-509: a novel antiandrogen for prostate cancer treatment.
Journal: Cancer research 20120315
Title: DCE and DW MRI in monitoring response to androgen deprivation therapy in patients with prostate cancer: a feasibility study.
Journal: Magnetic resonance in medicine 20120301
Title: Learning from estrogen receptor antagonism: structure-based identification of novel antiandrogens effective against multiple clinically relevant androgen receptor mutants.
Journal: Chemical biology & drug design 20120301
Title: Methoxychalcone inhibitors of androgen receptor translocation and function.
Journal: Bioorganic & medicinal chemistry letters 20120301
Title: Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth.
Journal: The Prostate 20120201
Title: A comparative assessment of α-lipoic acid N-phenylamides as non-steroidal androgen receptor antagonists both on and off gold nanoparticles.
Journal: Bioorganic chemistry 20120201
Title: Synthesis and characterization of bicalutamide-loaded magnetic nanoparticles as anti-tumor drug carriers.
Journal: Journal of nanoscience and nanotechnology 20120201
Title: Antiandrogenic, maspin induction, and antiprostate cancer activities of tanshinone IIA and its novel derivatives with modification in ring A.
Journal: Journal of medicinal chemistry 20120126
Title: Galbanic acid decreases androgen receptor abundance and signaling and induces G1 arrest in prostate cancer cells.
Journal: International journal of cancer 20120101
Title: Higher percentage of positive biopsy cores and Gleason score are associated with a greater degree of prostate gland shrinkage after neoadjuvant cytoreductive therapy.
Journal: Brachytherapy 20120101
Title: Understanding the performance of melt-extruded poly(ethylene oxide)-bicalutamide solid dispersions: characterisation of microstructural properties using thermal, spectroscopic and drug release methods.
Journal: Journal of pharmaceutical sciences 20120101
Title: Combined treatment with bicalutamide and anastrozole in a young boy with peripheral precocious puberty due to McCune-Albright Syndrome.
Journal: Endocrine journal 20120101
Title: Design, synthesis, and biological evaluation of 4-phenylpyrrole derivatives as novel androgen receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20120101
Title: Short-term clinicopathological outcome of neoadjuvant chemohormonal therapy comprising complete androgen blockade, followed by treatment with docetaxel and estramustine phosphate before radical prostatectomy in Japanese patients with high-risk localized prostate cancer.
Journal: World journal of surgical oncology 20120101
Title: The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation.
Journal: Breast cancer research : BCR 20120101
Title: The relative bioavailability study and fasting and fed states pharmacokinetics of bicalutamide 50-mg tablets in healthy Chinese volunteers.
Journal: Arzneimittel-Forschung 20120101
Title: ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.
Journal: Neoplasia (New York, N.Y.) 20120101
Title: Photosensitive drug eruption induced by bicalutamide within the UVB action spectrum.
Journal: European journal of dermatology : EJD 20120101
Title: Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening.
Journal: PloS one 20120101
Title: Successful Treatment of Advanced Metastatic Prostate Cancer following Chemotherapy Based on Molecular Profiling.
Journal: Case reports in oncology 20120101
Title: A study of plasma bicalutamide concentrations in hemodialysis patients.
Journal: Urologia internationalis 20120101
Title: [Clinico-pathological conference report: sudden deterioration of general condition, hypokalemia and diabetes in an elderly man].
Journal: Duodecim; laaketieteellinen aikakauskirja 20120101
Title: Clinical efficacy of primary combined androgen blockade for Japanese men with clinically localized prostate cancer unsuitable for local definitive treatment: a single institution experience.
Journal: International journal of clinical oncology 20111201
Title: Interstitial pneumonitis induced by bicalutamide given for prostate cancer.
Journal: International journal of clinical oncology 20111201
Title: Circadian rhythm of hot flashes and activity levels among prostate cancer patients on androgen deprivation therapy.
Journal: The aging male : the official journal of the International Society for the Study of the Aging Male 20111201
Title: Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models.
Journal: Endocrinology 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Liquid antisolvent precipitation process for solubility modulation of bicalutamide.
Journal: Acta pharmaceutica (Zagreb, Croatia) 20111201
Title: Modulation of the tumor cell death pathway by androgen receptor in response to cytotoxic stimuli.
Journal: Journal of cellular physiology 20111101
Title: Androgen deprivation therapy influences the uptake of 11C-choline in patients with recurrent prostate cancer: the preliminary results of a sequential PET/CT study.
Journal: European journal of nuclear medicine and molecular imaging 20111101
Title: Androgen suppresses proliferation of castration-resistant LNCaP 104-R2 prostate cancer cells through androgen receptor, Skp2, and c-Myc.
Journal: Cancer science 20111101
Title: Tetrahydroquinolines as a novel series of nonsteroidal selective androgen receptor modulators: structural requirements for better physicochemical and biological properties.
Journal: Bioorganic & medicinal chemistry letters 20111101
Title: Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening.
Journal: Journal of medicinal chemistry 20110922
Title: Androgen receptor and heterogeneous nuclear ribonucleoprotein K colocalize in the nucleoplasm and are modulated by bicalutamide and 4-hydroxy-tamoxifen in prostatic cancer cell lines.
Journal: The Prostate 20110915
Title: Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291.
Journal: The Prostate 20110901
Title: Hunterian Lecture. Characterisation of human prostate epithelial progenitor differentiation in response to androgens.
Journal: Annals of the Royal College of Surgeons of England 20110901
Title: Targeting androgen receptor in estrogen receptor-negative breast cancer.
Journal: Cancer cell 20110712
Title: Antivascular effects of neoadjuvant androgen deprivation for prostate cancer: an in vivo human study using susceptibility and relaxivity dynamic MRI.
Journal: International journal of radiation oncology, biology, physics 20110701
Title: Preliminary study with bicalutamide in heterosexual and homosexual patients with prostate cancer: a possible implication of androgens in male homosexual arousal.
Journal: BJU international 20110701
Title: Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies.
Journal: The Journal of clinical investigation 20110701
Title: Unexpected binding orientation of bulky-B-ring anti-androgens and implications for future drug targets.
Journal: Journal of medicinal chemistry 20110609
Title: Bicalutamide monotherapy preserves bone mineral density, muscle strength and has significant health-related quality of life benefits for osteoporotic men with prostate cancer.
Journal: BJU international 20110601
Title: Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer.
Journal: BJU international 20110601
Title: Androgen receptor-positive salivary duct carcinoma: a disease entity with promising new treatment options.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601
Title: Up-regulation of insulin-like growth factor-binding protein 3 by 5-fluorouracil (5-FU) leads to the potent anti-proliferative effect of androgen deprivation therapy combined with 5-FU in human prostate cancer cell lines.
Journal: International journal of oncology 20110601
Title: [Results of 125-iodine seed implant with preplanning system in 250 patients with prostate cancer].
Journal: Actas urologicas espanolas 20110601
Title: [Alternative antiandrogen therapy with flutamide in patients with castration-resistant prostate cancer : a single center experience].
Journal: Hinyokika kiyo. Acta urologica Japonica 20110601
Title: Adjuvant androgen deprivation for high-risk prostate cancer after radical prostatectomy: SWOG S9921 study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520
Title: Mechanism of androgen receptor antagonism by bicalutamide in the treatment of prostate cancer.
Journal: Biochemistry 20110517
Title: The antiandrogenic effect of finasteride against a mutant androgen receptor.
Journal: Cancer biology & therapy 20110515
Title: Residual prostate cancer in patients treated with endocrine therapy with or without radical radiotherapy: a side study of the SPCG-7 randomized trial.
Journal: International journal of radiation oncology, biology, physics 20110501
Title: Comment on 'Androgen-hypersensitive preclinical model of prostate cancer' by Kawata et al.
Journal: The Prostate 20110501
Title: Androgen stimulates endothelial cell proliferation via an androgen receptor/VEGF/cyclin A-mediated mechanism.
Journal: American journal of physiology. Heart and circulatory physiology 20110401
Title: Testosterone, not 5α-dihydrotestosterone, stimulates LRH-1 leading to FSH-independent expression of Cyp19 and P450scc in granulosa cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20110401
Title: Prostate adenocarcinoma with orbital metastasis in an HIV+ man.
Journal: The Canadian journal of urology 20110401
Title: Influence of short polyglutamine tracts and p160 coactivators on the transactivation of the androgen receptor.
Journal: Cancer biotherapy & radiopharmaceuticals 20110401
Title: Monte Carlo studies of drug nucleation 1: formation of crystalline clusters of bicalutamide in water.
Journal: The journal of physical chemistry. B 20110331
Title: Design and synthesis of tricyclic tetrahydroquinolines as a new series of nonsteroidal selective androgen receptor modulators (SARMs).
Journal: Bioorganic & medicinal chemistry letters 20110315
Title: Cell-cycle regulators cdk2ap1 and bicalutamide suppress malignant biological interactions between prostate cancer and bone cells.
Journal: The Prostate 20110301
Title: Dehydroepiandrosterone fatty acyl esters in high density lipoprotein: interaction with human vascular endothelial cells and vascular responses ex vivo.
Journal: Steroids 20110301
Title: Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells.
Journal: International journal of oncology 20110301
Title: Formation of bicalutamide nanodispersion for dissolution rate enhancement.
Journal: International journal of pharmaceutics 20110214
Title: Depression related to (neo)adjuvant hormonal therapy for prostate cancer.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110201
Title: Arylpiperazines for management of benign prostatic hyperplasia: design, synthesis, quantitative structure-activity relationships, and pharmacokinetic studies.
Journal: Journal of medicinal chemistry 20110113
Title: Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells.
Journal: Molecular and cellular endocrinology 20110101
Title: Combined androgen blockade for prostate cancer: review of efficacy, safety and cost-effectiveness.
Journal: Cancer science 20110101
Title: Daily phosphodiesterase type 5 inhibitor therapy as rescue for recurrent ischemic priapism after failed androgen ablation.
Journal: Journal of andrology 20110101
Title: [Disseminated carcinomatosis of the bone marrow in two patients with prostate cancer].
Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20110101
Title: Androgen receptor antagonists and anti-prostate cancer activities of some synthesized steroidal candidates.
Journal: Chemical & pharmaceutical bulletin 20110101
Title: [Impact of neoadjuvant hormonal therapy on the permanent ¹²⁵I-seed brachytherapy for localized high-risk prostate cancer].
Journal: Zhonghua yi xue za zhi 20101228
Title: Preferential induction of G1 arrest in androgen-responsive human prostate cancer cells by androgen receptor signaling antagonists DL3 and antiandrogen bicalutamide.
Journal: Cancer letters 20101208
Title: Interaction between AR signalling and CRKL bypasses casodex inhibition in prostate cancer.
Journal: Cellular signalling 20101201
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer.
Journal: Bioorganic & medicinal chemistry 20101201
Title: Relative bioavailability and tolerability of two formulations of bicalutamide 50-mg tablets: a randomized-sequence, open-label, two-period crossover study in healthy Korean male subjects.
Journal: Clinical therapeutics 20101201
Title: Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.
Journal: Human molecular genetics 20101115
Title: Novel selective anti-androgens with a diphenylpentane skeleton.
Journal: Bioorganic & medicinal chemistry letters 20101115
Title: An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.
Journal: The Journal of biological chemistry 20101112
Title: Salvage therapy with bicalutamide 150 mg in nonmetastatic castration-resistant prostate cancer.
Journal: Urology 20101101
Title: Alternative antiandrogen therapy in patients with castration-resistant prostate cancer: a single-center experience.
Journal: International journal of urology : official journal of the Japanese Urological Association 20101101
Title: No long-term effects of hormonal therapy preceding brachytherapy on urinary function and health-related quality of life among prostate cancer patients.
Journal: Urology 20101101
Title: The antiandrogen bicalutamide activates the androgen receptor (AR) with a mutation in codon 741 through the mitogen activated protein kinase (MARK) pathway in human prostate cancer PC3 cells.
Journal: Oncology reports 20101101
Title: Developments in nonsteroidal antiandrogens targeting the androgen receptor.
Journal: ChemMedChem 20101004
Title: Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men.
Journal: American journal of physiology. Endocrinology and metabolism 20101001
Title: Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: a mechanistic model supporting prevention strategies.
Journal: International journal of oncology 20101001
Title: Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival.
Journal: Anticancer research 20101001
Title: Bicalutamide plus anastrozole for the treatment of gonadotropin-independent precocious puberty in boys with testotoxicosis: a phase II, open-label pilot study (BATT).
Journal: Journal of pediatric endocrinology & metabolism : JPEM 20101001
Title: Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR.
Journal: British journal of cancer 20100928
Title: A prospective phase III randomized trial of hypofractionation versus conventional fractionation in patients with high-risk prostate cancer.
Journal: International journal of radiation oncology, biology, physics 20100901
Title: Detection of androgen receptor mutations in circulating tumor cells in castration-resistant prostate cancer.
Journal: Clinical chemistry 20100901
Title: Efficacy of maximal androgen blockade versus castration alone in the treatment of advanced prostate cancer: a retrospective clinical experience from a Chinese medical centre.
Journal: Asian journal of andrology 20100901
Title: Bicalutamide and third-generation aromatase inhibitors in testotoxicosis.
Journal: Pediatrics 20100901
Title: 5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors.
Journal: The Prostate 20100801
Title: Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0(2,6)]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20100801
Title: AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model.
Journal: Journal of cellular biochemistry 20100801
Title: Is prophylactic breast radiotherapy necessary in all patients with prostate cancer and gynecomastia and/or breast pain?
Journal: The Journal of urology 20100801
Title: Androgen blockade for the treatment of high-flow priapism.
Journal: The journal of sexual medicine 20100701
Title: Telomerase as an important target of androgen signaling blockade for prostate cancer treatment.
Journal: Molecular cancer therapeutics 20100701
Title: Management of thrombotic thrombocytopenic purpura in metastatic prostate cancer with only endocrine therapy.
Journal: Annals of the Academy of Medicine, Singapore 20100701
Title: Comparative study of new shell-type, sub-2 micron fully porous and monolith stationary phases, focusing on mass-transfer resistance.
Journal: Journal of chromatography. A 20100604
Title: Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity.
Journal: The Prostate 20100515
Title: Relationship between bone mineral density and androgen-deprivation therapy in Japanese prostate cancer patients.
Journal: Urology 20100501
Title: Structure-activity relationships of bioisosteric replacement of the carboxylic acid in novel androgen receptor pure antagonists.
Journal: Bioorganic & medicinal chemistry 20100501
Title: Editorial comment.
Journal: Urology 20100501
Title: Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC).
Journal: Journal of medicinal chemistry 20100408
Title: Androgen receptor interacts with telomeric proteins in prostate cancer cells.
Journal: The Journal of biological chemistry 20100402
Title: Establishment and characterization of an androgen receptor-dependent, androgen-independent human prostate cancer cell line, LNCaP-CS10.
Journal: The Prostate 20100401
Title: Frequency of zoledronic acid to prevent further bone loss in osteoporotic patients undergoing androgen deprivation therapy for prostate cancer.
Journal: BJU international 20100401
Title: 1{alpha},25-Dihydroxyvitamin D3 inhibits growth of VCaP prostate cancer cells despite inducing the growth-promoting TMPRSS2:ERG gene fusion.
Journal: Endocrinology 20100401
Title: Antiandrogen monotherapy in patients with localized or locally advanced prostate cancer: final results from the bicalutamide Early Prostate Cancer programme at a median follow-up of 9.7 years.
Journal: BJU international 20100401
Title: Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase.
Journal: Prostate cancer and prostatic diseases 20100301
Title: Subjective and objective measures of late genitourinary morbidity following hypofractionated radiotherapy in men with prostate cancer.
Journal: Prostate cancer and prostatic diseases 20100301
Title: Physicochemical characterization of hot melt extruded bicalutamide-polyvinylpyrrolidone solid dispersions.
Journal: Journal of pharmaceutical sciences 20100301
Title: Antagonistic interaction between bicalutamide (Casodex) and radiation in androgen-positive prostate cancer LNCaP cells.
Journal: The Prostate 20100301
Title: Self-assembling methoxypoly(ethylene glycol)-b-poly(carbonate-co-L-lactide) block copolymers for drug delivery.
Journal: Biomaterials 20100301
Title: REDD1 is a major target of testosterone action in preventing dexamethasone-induced muscle loss.
Journal: Endocrinology 20100301
Title: The pure anti-androgen bicalutamide inhibits cyclin A expression both in androgen-dependent and -independent cell lines.
Journal: International journal of oncology 20100301
Title: [Bicalutamide].
Journal: Revue de l'infirmiere 20100301
Title: Antiandrogen withdrawal syndrome and alternative antiandrogen therapy associated with the W741C mutant androgen receptor in a novel prostate cancer xenograft.
Journal: The Prostate 20100215
Title: Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.
Journal: The Journal of biological chemistry 20100212
Title: An open, randomised, multicentre, phase 3 trial comparing the efficacy of two tamoxifen schedules in preventing gynaecomastia induced by bicalutamide monotherapy in prostate cancer patients.
Journal: European urology 20100201
Title: A randomized controlled trial of add-back estrogen or placebo on cognition in men with prostate cancer receiving an antiandrogen and a gonadotropin-releasing hormone analog.
Journal: Psychoneuroendocrinology 20100201
Title: Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A.
Journal: International journal of cancer 20100201
Title: Induction of bicalutamide sensitivity in prostate cancer cells by an epigenetic Puralpha-mediated decrease in androgen receptor levels.
Journal: The Prostate 20100201
Title: Metastatic prostatic adenocarcinoma mimicking inflammatory breast carcinoma: a case report.
Journal: Clinical breast cancer 20100201
Title: Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors.
Journal: Urologia internationalis 20100101
Title: Hormonal therapy of prostate cancer.
Journal: Progress in brain research 20100101
Title: Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer.
Journal: PloS one 20100101
Title: The effect of concurrent androgen deprivation and 3D conformal radiotherapy on prostate volume and clinical organ doses during treatment for prostate cancer.
Journal: The British journal of radiology 20091201
Title: Organotypic cultures of prepubertal mouse testes: a method to study androgen action in sertoli cells while preserving their natural environment.
Journal: Biology of reproduction 20091201
Title: Comparative pharmacokinetic evaluation of two formulations of bicalutamide 50-mg tablets: an open-label, randomized-sequence, single-dose, two-period crossover study in healthy Korean male volunteers.
Journal: Clinical therapeutics 20091201
Title: Treatment of familial male-limited precocious puberty (testotoxicosis) with anastrozole and bicalutamide in a boy with a novel mutation in the luteinizing hormone receptor.
Journal: Journal of pediatric endocrinology & metabolism : JPEM 20091201
Title: Disseminated intravascular coagulation secondary to metastatic prostate cancer: case report and review of the literature.
Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20091201
Title: Development of carcinoid tumour in hormonally treated adenocarcinoma of the prostate.
Journal: European urology 20091101
Title: A 16-year clinical experience with intermittent androgen deprivation for prostate cancer: oncological results.
Journal: World journal of urology 20091001
Title: Pathological effects of prostate cancer correlate with neuroendocrine differentiation and PTEN expression after bicalutamide monotherapy.
Journal: The Journal of urology 20091001
Title: Dutasteride and bicalutamide in patients with hormone-refractory prostate cancer: the Therapy Assessed by Rising PSA (TARP) study rationale and design.
Journal: The Canadian journal of urology 20091001
Title: Design and synthesis of androgen receptor antagonists with bulky side chains for overcoming antiandrogen resistance.
Journal: Journal of medicinal chemistry 20090910
Title: Radiation dose predicts for biochemical control in intermediate-risk prostate cancer patients treated with low-dose-rate brachytherapy.
Journal: International journal of radiation oncology, biology, physics 20090901
Title: Long-term changes in bone mineral density and predicted fracture risk in patients receiving androgen-deprivation therapy for prostate cancer, with stratification of treatment based on presenting values.
Journal: BJU international 20090901
Title: Characterization of choline uptake in prostate cancer cells following bicalutamide and docetaxel treatment.
Journal: European journal of nuclear medicine and molecular imaging 20090901
Title: Micellar delivery of bicalutamide and embelin for treating prostate cancer.
Journal: Pharmaceutical research 20090901
Title: Bicalutamide demonstrates biologic effectiveness in prostate cancer cell lines and tumor primary cultures irrespective of Her2/neu expression levels.
Journal: Urology 20090801
Title: Twenty years of controversy surrounding combined androgen blockade for advanced prostate cancer.
Journal: Cancer 20090801
Title: Combined androgen blockade with bicalutamide for advanced prostate cancer: long-term follow-up of a phase 3, double-blind, randomized study for survival.
Journal: Cancer 20090801
Title: Androgen deprivation therapy regulation of beta1C integrin expression in prostate cancer.
Journal: Oncology reports 20090801
Title: [Androgens stimulate the expression of SOCS-3 and inhibits their effect on proliferation and secretion].
Journal: Aktuelle Urologie 20090801
Title: Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090801
Title: Interactions of methoxyacetic acid with androgen receptor.
Journal: Toxicology and applied pharmacology 20090715
Title: Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.
Journal: Toxicology and applied pharmacology 20090715
Title: Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts.
Journal: The Journal of steroid biochemistry and molecular biology 20090701
Title: High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats.
Journal: Talanta 20090615
Title: Duration of androgen suppression in the treatment of prostate cancer.
Journal: The New England journal of medicine 20090611
Title: Structure determination of chiral sulfoxide in diastereomeric bicalutamide derivatives.
Journal: Chirality 20090601
Title: Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090520
Title: Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo.
Journal: The Prostate 20090515
Title: Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy.
Journal: Cancer research 20090515
Title: Development of a second-generation antiandrogen for treatment of advanced prostate cancer.
Journal: Science (New York, N.Y.) 20090508
Title: Functional AR signaling is evident in an in vitro mouse follicle culture bioassay that encompasses most stages of folliculogenesis.
Journal: Biology of reproduction 20090401
Title: Genome-wide impact of androgen receptor trapped clone-27 loss on androgen-regulated transcription in prostate cancer cells.
Journal: Cancer research 20090401
Title: Phase I-II trial of weekly bicalutamide in men with elevated prostate-specific antigen and negative prostate biopsies.
Journal: Cancer prevention research (Philadelphia, Pa.) 20090401
Title: Nanosized bicalutamide and its molecular structure in solvents.
Journal: International journal of pharmaceutics 20090331
Title: Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor.
Journal: Endocrine-related cancer 20090301
Title: Hot flashes during androgen deprivation therapy with luteinizing hormone-releasing hormone agonist combined with steroidal or nonsteroidal antiandrogen for prostate cancer.
Journal: Urology 20090301
Title: Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer.
Journal: Anti-cancer drugs 20090301
Title: Inhibition of androgen receptor transcriptional activity as a novel mechanism of action of arsenic.
Journal: Molecular endocrinology (Baltimore, Md.) 20090301
Title: Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2.
Journal: Molecular cancer therapeutics 20090301
Title: Profound bicalutamide withdrawal syndrome in a hormone-refractory T4N1 prostate cancer permitting both salvage radiotherapy and cessation of hormonal therapy.
Journal: International journal of urology : official journal of the Japanese Urological Association 20090301
Title: [Unreliable survival analysis].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090226
Title: [Incorrect about hormone treatment in prostatic cancer].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090226
Title: Mechanistic studies on the synthesis of bicalutamide.
Journal: Organic & biomolecular chemistry 20090221
Title: Individual variations of serum testosterone in patients with prostate cancer receiving androgen deprivation therapy.
Journal: BJU international 20090201
Title: Differential mechanisms of bicalutamide-induced apoptosis in prostate cell lines.
Journal: Prostate cancer and prostatic diseases 20090101
Title: Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists.
Journal: Prostate cancer and prostatic diseases 20090101
Title: A dynamic kinetic asymmetric transformation in the alpha-hydroxylation of racemic malonates and its application to biologically active molecules.
Journal: Angewandte Chemie (International ed. in English) 20090101
Title: Effect of androgen suppression compared with androgen receptor blockade on arterial stiffness in men with prostate cancer.
Journal: Journal of andrology 20090101
Title: Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival.
Journal: PloS one 20090101
Title: Long-term survival and PSA control with radiation and immunotherapy for node positive prostate cancer.
Journal: Clinical & developmental immunology 20090101
Title: 68Ga-DOTATOC-PET/CT detects neuroendocrine differentiation of prostate cancer metastases.
Journal: Nuklearmedizin. Nuclear medicine 20090101
Title: Bicalutamide failure in prostate cancer treatment: involvement of Multi Drug Resistance proteins.
Journal: European journal of pharmacology 20081228
Title: Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.
Journal: Molecular and cellular endocrinology 20081216
Title: Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer.
Journal: International journal of cancer 20081215
Title: Skip metastase on the left neck lymph nodes of the prostatic adenocarcinoma with neuroendocrine differentiation and accompanying thyroid micropapillary carcinoma.
Journal: Pathology oncology research : POR 20081201
Title: Evaluation of quality of life in patients with previously untreated advanced prostate cancer receiving maximum androgen blockade therapy or LHRHa monotherapy: a multicenter, randomized, double-blind, comparative study.
Journal: Journal of cancer research and clinical oncology 20081201
Title: Bicalutamide inhibits androgen-mediated adhesion of prostate cancer cells exposed to ionizing radiation.
Journal: The Prostate 20081201
Title: Prolonged androgen receptor loading onto chromatin and the efficient recruitment of p160 coactivators contribute to androgen-independent growth of prostate cancer cells.
Journal: The Prostate 20081201
Title: Anaemia following initiation of androgen deprivation therapy for metastatic prostate cancer: a retrospective chart review.
Journal: The aging male : the official journal of the International Society for the Study of the Aging Male 20081201
Title: Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival.
Journal: Oncogene 20081127
Title: [Hormone treatment of prostate cancer in Norway].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20081120
Title: Genistein combined polysaccharide enhances activity of docetaxel, bicalutamide and Src kinase inhibition in androgen-dependent and independent prostate cancer cell lines.
Journal: BJU international 20081101
Title: Molecular basis of agonicity and antagonicity in the androgen receptor studied by molecular dynamics simulations.
Journal: Journal of molecular graphics & modelling 20081101
Title: Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081020
Title: A novel dietary flavonoid fisetin inhibits androgen receptor signaling and tumor growth in athymic nude mice.
Journal: Cancer research 20081015
Title: Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins.
Journal: The Prostate 20081001
Title: Nucleation and crystal growth in supersaturated solutions of a model drug.
Journal: Journal of colloid and interface science 20080915
Title: Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.
Journal: Carcinogenesis 20080901
Title: Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade.
Journal: The Journal of urology 20080901
Title: Undetectable level of prostate specific antigen (PSA) nadir predicts PSA biochemical failure in local prostate cancer with delayed-combined androgen blockade.
Journal: Japanese journal of clinical oncology 20080901
Title: Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring.
Journal: Bioorganic & medicinal chemistry 20080901
Title: Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures.
Journal: Journal of chemical information and modeling 20080901
Title: Drug-related hepatotoxicity and hepatic failure following combined androgen blockade.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20080901
Title: Polymorph transitions of bicalutamide: a remarkable example of mechanical activation.
Journal: Journal of pharmaceutical sciences 20080801
Title: Bicalutamide-associated fulminant hepatotoxicity.
Journal: Pharmacotherapy 20080801
Title: Development and characterization of bicalutamide-poloxamer F68 solid dispersion systems.
Journal: Die Pharmazie 20080801
Title: Hormonal regulation of beta2-adrenergic receptor level in prostate cancer.
Journal: The Prostate 20080701
Title: Cytology of metastatic prostate cancer following orchiectomy and antiandrogen therapy: a diagnostic challenge.
Journal: Diagnostic cytopathology 20080701
Title: Antiandrogen withdrawal in castrate-refractory prostate cancer: a Southwest Oncology Group trial (SWOG 9426).
Journal: Cancer 20080601
Title: Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones.
Journal: Bioorganic & medicinal chemistry letters 20080601
Title: Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation.
Journal: Carcinogenesis 20080601
Title: 1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells.
Journal: The Prostate 20080515
Title: Chronic azacitidine treatment results in differentiating effects, sensitizes against bicalutamide in androgen-independent prostate cancer cells.
Journal: The Prostate 20080515
Title: Etoricoxib and intermittent androgen deprivation therapy in patients with biochemical progression after radical prostatectomy.
Journal: Urology 20080501
Title: Selective androgen receptor modulators based on a series of 7H-[1,4]oxazino[3,2-g]quinolin-7-ones with improved in vivo activity.
Journal: Bioorganic & medicinal chemistry letters 20080501
Title: Discovery and biological characterization of a novel series of androgen receptor modulators.
Journal: British journal of pharmacology 20080501
Title: Inhibition of apoptosis in prostate cancer cells by androgens is mediated through downregulation of c-Jun N-terminal kinase activation.
Journal: Neoplasia (New York, N.Y.) 20080501
Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.
Journal: Chemical research in toxicology 20080401
Title: Solid-state characterization and dissolution properties of bicalutamide-beta-cyclodextrin inclusion complex.
Journal: Die Pharmazie 20080401
Title: Maximal androgen blockade for advanced prostate cancer.
Journal: Best practice & research. Clinical endocrinology & metabolism 20080401
Title: Synthesis and structure-activity relationships of the first ferrocenyl-aryl-hydantoin derivatives of the nonsteroidal antiandrogen nilutamide.
Journal: Journal of medicinal chemistry 20080327
Title: Randomization reveals unexpected acute leukemias in Southwest Oncology Group prostate cancer trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320
Title: Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20080315
Title: The effect of combined androgen blockade on bone turnover and bone mineral density in men with prostate cancer.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080301
Title: The Early Prostate Cancer program: bicalutamide in nonmetastatic prostate cancer.
Journal: Expert review of anticancer therapy 20080301
Title: Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines.
Journal: The Prostate 20080215
Title: Isolation and characterization of process related impurities and degradation products of bicalutamide and development of RP-HPLC method for impurity profile study.
Journal: Journal of pharmaceutical and biomedical analysis 20080213
Title: Prospective study of depression and fatigue in men with advanced prostate cancer receiving hormone therapy.
Journal: Psycho-oncology 20080201
Title: Adipocytokines, obesity, and insulin resistance during combined androgen blockade for prostate cancer.
Journal: Urology 20080201
Title: Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer.
Journal: Prostate cancer and prostatic diseases 20080101
Title: Anti-androgens increase N-terminal pro-BNP levels in men with prostate cancer.
Journal: Clinical endocrinology 20080101
Title: Downregulation of thymosin beta4 expression by androgen in prostate cancer LNCaP cells.
Journal: Journal of andrology 20080101
Title: The intracellular and nuclear-targeted delivery of an antiandrogen drug by carrier peptides.
Journal: Biopolymers 20080101
Title: Bicalutamide alone prior to brachytherapy achieves cytoreduction that is similar to luteinizing hormone-releasing hormone analogues with less patient-reported morbidity.
Journal: Urologic oncology 20080101
Title: AKT regulates androgen receptor-dependent growth and PSA expression in prostate cancer.
Journal: Advances in experimental medicine and biology 20080101
Title: Adjuvant hormonal treatment - the bicalutamide early prostate cancer program.
Journal: Frontiers of radiation therapy and oncology 20080101
Title: Quantum dots-based multiplexed immunohistochemistry of protein expression in human prostate cancer cells.
Journal: European journal of histochemistry : EJH 20080101
Title: Prostate specific antigen (PSA) may be a poor marker for progression of prostate cancer after treatment with a combination of chemo-hormonal therapies.
Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20080101
Title: Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects.
Journal: PloS one 20080101
Title: A dramatic, objective antiandrogen withdrawal response: case report and review of the literature.
Journal: Journal of hematology & oncology 20080101
Title: Spectrophotometric estimation of bicalutamide in tablets.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer.
Journal: Oncogene 20071206
Title: A phase II evaluation of goserelin and bicalutamide in patients with ovarian cancer in second or higher complete clinical disease remission.
Journal: Cancer 20071201
Title: Treatment of bicalutamide-induced breast events.
Journal: Expert review of anticancer therapy 20071201
Title: A feasibility study evaluating the functional diffusion map as a predictive imaging biomarker for detection of treatment response in a patient with metastatic prostate cancer to the bone.
Journal: Neoplasia (New York, N.Y.) 20071201
Title: The efficacy of neoadjuvant androgen deprivation therapy as a prostate volume reduction before brachytherapy for clinically localized prostate cancer.
Journal: Acta medica Okayama 20071201
Title: Gefitinib and bicalutamide show synergistic effects in primary cultures of prostate cancer derived from androgen-dependent naive patients.
Journal: Oncology reports 20071101
Title: [Regression of a choroidal metastasis from prostate adenocarcinoma after hormonal therapy].
Journal: Archivos de la Sociedad Espanola de Oftalmologia 20071101
Title: Discovery and structure-activity relationships of new steroidal compounds bearing a carboxy-terminal side chain as androgen receptor pure antagonists.
Journal: Bioorganic & medicinal chemistry letters 20071015
Title: Redefining clinically significant castration levels in patients with prostate cancer receiving continuous androgen deprivation therapy.
Journal: The Journal of urology 20071001
Title: Current status of endocrine therapy for prostate cancer in Japan analysis of primary androgen deprivation therapy on the basis of data collected by J-CaP.
Journal: Japanese journal of clinical oncology 20071001
Title: Surgical and biologic outcomes after neoadjuvant bicalutamide treatment in prostate cancer.
Journal: Urology 20071001
Title: Androgen receptor-mediated repression of novel target genes.
Journal: The Prostate 20070915
Title: PC-1/PrLZ contributes to malignant progression in prostate cancer.
Journal: Cancer research 20070915
Title: A 90 kDa fragment of filamin A promotes Casodex-induced growth inhibition in Casodex-resistant androgen receptor positive C4-2 prostate cancer cells.
Journal: Oncogene 20070906
Title: The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population.
Journal: Journal of cellular physiology 20070901
Title: In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma.
Journal: The Prostate 20070901
Title: Androgen-dependent regulation of medium and long chain fatty acids uptake in prostate cancer.
Journal: The Prostate 20070901
Title: Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents.
Journal: Acta pharmacologica Sinica 20070901
Title: Does small-cell phenotype predict the natural history of prostate cancer? A case study in disease behavior.
Journal: Nature clinical practice. Oncology 20070901
Title: Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors.
Journal: Cancer research 20070901
Title: Prostate-cancer-specific survival and clinical progression-free survival in men with prostate cancer treated intermittently with testosterone-inactivating pharmaceuticals.
Journal: Urology 20070901
Title: [Solitary peritoneal carcinomatosis in prostate cancer].
Journal: Aktuelle Urologie 20070901
Title: Bicalutamide increases phospho-Akt levels through Her2 in patients with prostate cancer.
Journal: Endocrine-related cancer 20070901
Title: Complete remission of metastatic carcinoma of the prostate with bicalutamide withdrawal.
Journal: Clinical genitourinary cancer 20070901
Title: Androgen receptor or estrogen receptor-beta blockade alters DHEA-, DHT-, and E(2)-induced proliferation and PSA production in human prostate cancer cells.
Journal: The Prostate 20070801
Title: Increased resistance to trail-induced apoptosis in prostate cancer cells selected in the presence of bicalutamide.
Journal: The Prostate 20070801
Title: Discovery of antiandrogen activity of nonsteroidal scaffolds of marketed drugs.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20070717
Title: Bicalutamide-induced gynaecomastia: do we have the answer?
Journal: European urology 20070701
Title: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.
Journal: European urology 20070701
Title: Editorial comment on: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.
Journal: European urology 20070701
Title: Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia.
Journal: The Prostate 20070701
Title: Androgen withdrawal in patients reduces prostate cancer hypoxia: implications for disease progression and radiation response.
Journal: Cancer research 20070701
Title: A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells.
Journal: Molecular cancer therapeutics 20070701
Title: [Locally advanced prostate cancer: definition, prognosis and treatment].
Journal: Bulletin du cancer 20070701
Title: Labeling and identification of LNCaP cell surface proteins: a pilot study.
Journal: The Prostate 20070615
Title: Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors.
Journal: The Prostate 20070601
Title: Androgen regulation of aldehyde dehydrogenase 1A3 (ALDH1A3) in the androgen-responsive human prostate cancer cell line LNCaP.
Journal: Experimental biology and medicine (Maywood, N.J.) 20070601
Title: Epigallocatechin-3-gallate and bicalutamide cause growth arrest and apoptosis in NRP-152 and NRP-154 prostate epithelial cells.
Journal: International journal of urology : official journal of the Japanese Urological Association 20070601
Title: [Role of 150 mg bicalutamide in the treatment of prostate cancer: 3rd analysis of the EPC (early prostate cancer) program].
Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20070601
Title: Prostate cancer tissue is masked by bicalutamide: a case report.
Journal: European journal of medical research 20070529
Title: Reactive oxygen species mediate androgen receptor- and serum starvation-elicited downstream signaling of ADAM9 expression in human prostate cancer cells.
Journal: The Prostate 20070515
Title: Non-steroidal antiandrogens act as AF-1 agonists under conditions of high androgen-receptor expression.
Journal: The Prostate 20070501
Title: Cushing syndrome associated with prostatic tumor adrenocorticotropic hormone (ACTH) expression after maximal androgen blockade therapy.
Journal: International journal of urology : official journal of the Japanese Urological Association 20070501
Title: Circumventing anti-androgen resistance by molecular design.
Journal: Journal of the American Chemical Society 20070404
Title: Bicalutamide 50 mg monotherapy in patients with isolated high-grade PIN: findings in repeat biopsies at 6 months.
Journal: Journal of clinical pathology 20070401
Title: EZH2 promotes proliferation and invasiveness of prostate cancer cells.
Journal: The Prostate 20070401
Title: RADICALS (Radiotherapy and Androgen Deprivation in Combination after Local Surgery).
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20070401
Title: Nuclear and membrane receptor-mediated signalling pathways modulate polyamine biosynthesis and interconversion.
Journal: Biochemical Society transactions 20070401
Title: Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones.
Journal: Bioorganic & medicinal chemistry letters 20070315
Title: Synthesis and biological evaluation of [18F]bicalutamide, 4-[76Br]bromobicalutamide, and 4-[76Br]bromo-thiobicalutamide as non-steroidal androgens for prostate cancer imaging.
Journal: Journal of medicinal chemistry 20070308
Title: Ligand-specific dynamics of the androgen receptor at its response element in living cells.
Journal: Molecular and cellular biology 20070301
Title: Long-term effectiveness of luteinizing hormone-releasing hormone agonist or antiandrogen monotherapy in elderly men with localized prostate cancer (T1-2): a retrospective study.
Journal: Asian journal of andrology 20070301
Title: Prostate-specific antigen half-life and pretreatment prostate-specific antigen: crucial predictors for prostate-specific antigen trend in delayed-combined androgen blockade therapy.
Journal: International journal of urology : official journal of the Japanese Urological Association 20070301
Title: Effects of flutamide as a second-line agent for maximum androgen blockade of hormone refractory prostate cancer.
Journal: International journal of urology : official journal of the Japanese Urological Association 20070301
Title: 2-(2,2,2-Trifluoroethyl)-5,6-dichlorobenzimidazole derivatives as potent androgen receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20070215
Title: Prosaposin upregulates AR and PSA expression and activity in prostate cancer cells (LNCaP).
Journal: The Prostate 20070201
Title: A role for neurotensin in bicalutamide resistant prostate cancer cells.
Journal: The Prostate 20070201
Title: Synthesis and SAR of potent and selective androgen receptor antagonists: 5,6-Dichloro-benzimidazole derivatives.
Journal: Bioorganic & medicinal chemistry letters 20070201
Title: The role of tamoxifen in reducing bicalutamide-induced gynaecomastia and breast pain.
Journal: BJU international 20070201
Title: [Giant prostate carcinoma treated effectively with endocrine therapy: case report].
Journal: Hinyokika kiyo. Acta urologica Japonica 20070201
Title: [Gynecomastia as a complication of hormonotherapy for prostate cancer: effect of prophylactic breast irradiation].
Journal: Harefuah 20070201
Title: Differential regulation of clusterin and its isoforms by androgens in prostate cells.
Journal: The Journal of biological chemistry 20070126
Title: [Hormonal treatment of cancer of the prostate: review and present status].
Journal: Deutsche medizinische Wochenschrift (1946) 20070126
Title: The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.
Journal: Biochemistry 20070123
Title: Conformational polymorphism in bicalutamide.
Journal: International journal of pharmaceutics 20070110
Title: Dual androgen-response elements mediate androgen regulation of MMP-2 expression in prostate cancer cells.
Journal: Asian journal of andrology 20070101
Title: Discovery of 7alpha-substituted dihydrotestosterones as androgen receptor pure antagonists and their structure-activity relationships.
Journal: Bioorganic & medicinal chemistry 20070101
Title: The discovery of a potent orally efficacious indole androgen receptor antagonist through in vivo screening.
Journal: Bioorganic & medicinal chemistry letters 20070101
Title: Bicalutamide (Casodex) 150 mg plus standard care in early non-metastatic prostate cancer: results from Early Prostate Cancer Trial 24 at a median 7 years' follow-up.
Journal: Prostate cancer and prostatic diseases 20070101
Title: Evaluation of an in vitro model of androgen ablation and identification of the androgen responsive proteome in LNCaP cells.
Journal: Proteomics 20070101
Title: Bicalutamide 80 mg combined with a luteinizing hormone-releasing hormone agonist (LHRH-A) versus LHRH-A monotherapy in advanced prostate cancer: findings from a phase III randomized, double-blind, multicenter trial in Japanese patients.
Journal: Prostate cancer and prostatic diseases 20070101
Title: Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation.
Journal: Molecular cancer therapeutics 20070101
Title: Global update on defining and treating high-risk localized prostate cancer with leuprorelin: a Japanese perspective--the effect of primary androgen deprivation therapy on stage C prostate cancer.
Journal: BJU international 20070101
Title: Spotlight on bicalutamide 150mg in the treatment of locally advanced prostate cancer.
Journal: Drugs & aging 20070101
Title: Androgen induces adaptation to oxidative stress in prostate cancer: implications for treatment with radiation therapy.
Journal: Neoplasia (New York, N.Y.) 20070101
Title: Neuroendocrine differentiation of localized prostate cancer during endocrine therapy.
Journal: Scandinavian journal of urology and nephrology 20070101
Title: Cancer-specific mortality after radiation therapy with short-course hormonal therapy or radical prostatectomy in men with localized, intermediate-risk to high-risk prostate cancer.
Journal: Cancer 20061201
Title: A randomized phase III study of neoadjuvant hormonal therapy in patients with localized prostate cancer.
Journal: Clinical genitourinary cancer 20061201
Title: [Early prostate cancer 2005. New 2005 data].
Journal: Annales d'urologie 20061201
Title: [Management of gynecomastia induced by bicalutamide].
Journal: Annales d'urologie 20061201
Title: Synthesis and SAR of novel hydantoin derivatives as selective androgen receptor modulators.
Journal: Bioorganic & medicinal chemistry letters 20061115
Title: A bioisosteric approach to the discovery of indole carbinol androgen receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20061101
Title: Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens.
Journal: Cancer research 20061101
Title: [Prostate small cell carcinoma: report of two cases that differed in treatment responsiveness].
Journal: Hinyokika kiyo. Acta urologica Japonica 20061101
Title: Androgen induction of prostate cancer cell invasion is mediated by ezrin.
Journal: The Journal of biological chemistry 20061006
Title: Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model.
Journal: The Prostate 20061001
Title: An improved and validated LC method for resolution of bicalutamide enantiomers using amylose tris-(3,5-dimethylphenylcarbamate) as a chiral stationary phase.
Journal: Journal of pharmaceutical and biomedical analysis 20060926
Title: Tolerability, efficacy and pharmacokinetics of bicalutamide 300 mg, 450 mg or 600 mg as monotherapy for patients with locally advanced or metastatic prostate cancer, compared with castration.
Journal: BJU international 20060901
Title: Treatment of familial male-limited precocious puberty with bicalutamide and anastrozole.
Journal: The Journal of pediatrics 20060901
Title: Characteristics of bicalutamide solid dispersions and improvement of the dissolution.
Journal: Drug development and industrial pharmacy 20060901
Title: Pretreatment serum level of HER2/nue as a prognostic factor in metastatic prostate cancer patients about to undergo endocrine therapy.
Journal: International journal of urology : official journal of the Japanese Urological Association 20060901
Title: Distinct regulation by steroids of messenger RNAs for FSHR and CYP19A1 in bovine granulosa cells.
Journal: Biology of reproduction 20060801
Title: The effect of androgen deprivation therapy on fasting serum lipid and glucose parameters.
Journal: The Journal of urology 20060801
Title: Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells.
Journal: The American journal of pathology 20060801
Title: The addition of bicalutamide 150 mg to radiotherapy significantly improves overall survival in men with locally advanced prostate cancer.
Journal: Journal of cancer research and clinical oncology 20060801
Title: Hot flashes.
Journal: Clinical journal of oncology nursing 20060801
Title: Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility.
Journal: Journal of cellular biochemistry 20060701
Title: Conditional expression of PTEN alters the androgen responsiveness of prostate cancer cells.
Journal: The Prostate 20060701
Title: Digitate dermatosis responding to bicalutamide therapy.
Journal: Clinical and experimental dermatology 20060701
Title: Are bone scans necessary in men with low prostate specific antigen levels following localized therapy?
Journal: The Journal of urology 20060701
Title: The bicalutamide 150 mg early prostate cancer program: findings of the North American trial at 7.7-year median followup.
Journal: The Journal of urology 20060701
Title: Prostate specific antigen expression does not necessarily correlate with prostate cancer cell growth.
Journal: The Journal of urology 20060701
Title: Pathological changes of high-grade prostatic intraepithelial neoplasia and prostate cancer after monotherapy with bicalutamide 150 mg.
Journal: BJU international 20060701
Title: Efficacy of neoadjuvant bicalutamide and dutasteride as a cytoreductive regimen before prostate brachytherapy.
Journal: Urology 20060701
Title: Preliminary results of bicalutamide monotherapy on biochemical failure of localized prostate cancer.
Journal: Journal of the National Medical Association 20060701
Title: [8-month neoadjuvant hormonal therapy before radical prostatectomy for high-risk prostate cancer].
Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20060701
Title: Treatment of bicalutamide-induced gynecomastia with breast-reduction surgery in prostate cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060620
Title: Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands.
Journal: Bioorganic & medicinal chemistry letters 20060615
Title: GREB1 is a novel androgen-regulated gene required for prostate cancer growth.
Journal: The Prostate 20060601
Title: Deferred combined androgen blockade therapy using bicalutamide in patients with hormone-refractory prostate cancer during androgen deprivation monotherapy.
Journal: BJU international 20060601
Title: DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.
Journal: American journal of physiology. Endocrinology and metabolism 20060501
Title: Combined androgen blockade: an update.
Journal: The Urologic clinics of North America 20060501
Title: Failure of gonadotropin-releasing hormone agonists with and without sterile abscess formation at depot sites: insight into mechanisms?
Journal: Urology 20060501
Title: Differentially expressed genes in the prostate cancer cell line LNCaP after exposure to androgen and anti-androgen.
Journal: Cancer genetics and cytogenetics 20060415
Title: Spontaneous reporting of hepatotoxicity associated with antiandrogens: data from the Spanish pharmacovigilance system.
Journal: Pharmacoepidemiology and drug safety 20060401
Title: The expression of transcription factor activating transcription factor 3 in the human prostate and its regulation by androgen in prostate cancer.
Journal: The Journal of urology 20060401
Title: New perspective in the management of neuroendocrine differentiation in prostate adenocarcinoma.
Journal: International journal of clinical practice 20060401
Title: Intermittent androgen deprivation therapy may prolong the duration of androgen dependence of well-differentiated prostate cancer.
Journal: Hinyokika kiyo. Acta urologica Japonica 20060401
Title: Marked sexual dimorphism of lacrimal gland peroxidase in hamster: repression by androgens and estrogens.
Journal: Biochemical and biophysical research communications 20060324
Title: Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization.
Journal: Molecular endocrinology (Baltimore, Md.) 20060301
Title: The androgen receptor pathway is by-passed in prostate cancer cells generated after prolonged treatment with bicalutamide.
Journal: The Prostate 20060301
Title: Apples and oranges. Re: 7.4-year update of the ongoing bicalutamide Early Prostate Cancer (EPC) trial programme.
Journal: BJU international 20060301
Title: The third analysis of the bicalutamide Early Prostate Cancer programme.
Journal: BJU international 20060301
Title: Managing locally advanced prostate cancer: a urologist's and a patient's perspective.
Journal: Anti-cancer drugs 20060301
Title: [13th European Congress of Medical Oncology. Prevention of uterine cancer, adjuvant treatment of early prostate cancer and the promises of nanotechnology].
Journal: Revue medicale suisse 20060208
Title: Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells.
Journal: The Journal of clinical endocrinology and metabolism 20060201
Title: Bicalutamide 150 mg plus standard care vs standard care alone for early prostate cancer.
Journal: BJU international 20060201
Title: [A case of prostatic cancer discovered from lung metastatic lesions].
Journal: Hinyokika kiyo. Acta urologica Japonica 20060201
Title: (+)-(2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl-N-[6-(trifluoromethyl)pyridin-3- yl]piperazine-1-carboxamide (YM580) as an orally potent and peripherally selective nonsteroidal androgen receptor antagonist.
Journal: Journal of medicinal chemistry 20060126
Title: Side-effects of treatments for locally advanced prostate cancer.
Journal: BJU international 20060101
Title: Persistence of prostatic intraepithelial neoplasia after effective chemoprevention of microscopic prostate cancer with antiandrogen in a rat model.
Journal: The Journal of urology 20060101
Title: Screening for metabolically stable aryl-propionamide-derived selective androgen receptor modulators for doping control purposes.
Journal: Rapid communications in mass spectrometry : RCM 20060101
Title: [Transcriptional regulation of placental transforming growth factor-beta by calcitriol in prostate cancer cells is androgen-independent].
Journal: Molekuliarnaia biologiia 20060101
Title: Enhanced expression of heat shock protein 27 following neoadjuvant hormonal therapy is associated with poor clinical outcome in patients undergoing radical prostatectomy for prostate cancer.
Journal: Anticancer research 20060101
Title: Molecular markers and their prognostic impact in patients with advanced prostate cancer undergoing intermittent androgen suppression.
Journal: Prostate cancer and prostatic diseases 20060101
Title: Bicalutamide 150mg: a review of its use in the treatment of locally advanced prostate cancer.
Journal: Drugs 20060101
Title: Pharmacokinetics of two novel bicalutamide formulations in healthy male volunteers.
Journal: Pharmacology 20060101
Title: Influence of bicalutamide with or without tamoxifen or anastrozole on insulin-like growth factor 1 and binding proteins in prostate cancer patients.
Journal: The International journal of biological markers 20060101
Title: The limited significance of a longer duration of neoadjuvant hormonal therapy prior to radical prostatectomy for high-risk prostate cancer in Japanese men.
Journal: Urologia internationalis 20060101
Title: Failure to maintain a suppressed level of serum testosterone during long-acting depot luteinizing hormone-releasing hormone agonist therapy in patients with advanced prostate cancer.
Journal: Urologia internationalis 20060101
Title: Estrogen-receptor-alpha-positive extramammary Paget's disease treated with hormonal therapy.
Journal: Dermatology (Basel, Switzerland) 20060101
Title: Bicalutamide 150 mg in addition to standard care for patients with early non-metastatic prostate cancer: updated results from the Scandinavian Prostate Cancer Period Group-6 Study after a median follow-up period of 7.1 years.
Journal: Scandinavian journal of urology and nephrology 20060101
Title: High-performance liquid chromatographic enantioseparation of bicalutamide and its related compounds.
Journal: Journal of chromatography. A 20051209
Title: Complete androgen ablation suppresses prostate stem cell antigen (PSCA) mRNA expression in human prostate carcinoma.
Journal: The Prostate 20051201
Title: Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity.
Journal: The Prostate 20051201
Title: Secretoglobin 2A1 is under selective androgen control mediated by a peculiar binding site for Sp family transcription factors.
Journal: Molecular endocrinology (Baltimore, Md.) 20051201
Title: Gynecomastia and breast pain induced by adjuvant therapy with bicalutamide after radical prostatectomy in patients with prostate cancer: the role of tamoxifen and radiotherapy.
Journal: The Journal of urology 20051201
Title: Co-activator and co-repressor interplay on the human androgen receptor.
Journal: Andrologia 20051201
Title: Testotoxicosis: current viewpoint.
Journal: Pediatric endocrinology reviews : PER 20051201
Title: Direct agonist/antagonist functions of dehydroepiandrosterone.
Journal: Endocrinology 20051101
Title: Possible role of adaptive mutation in resistance to antiandrogen in prostate cancer cells.
Journal: The Prostate 20051101
Title: The patient's choice of androgen-deprivation therapy in locally advanced prostate cancer: bicalutamide, a gonadotrophin-releasing hormone analogue or orchidectomy.
Journal: BJU international 20051101
Title: Estrogenic induction of spermatogenesis in the hypogonadal (hpg) mouse: role of androgens.
Journal: Reproduction (Cambridge, England) 20051101
Title: Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient.
Journal: Cancer research 20051101
Title: Exploratory study of drug plasma levels during bicalutamide 150 mg therapy co-administered with tamoxifen or anastrozole for prophylaxis of gynecomastia and breast pain in men with prostate cancer.
Journal: Cancer chemotherapy and pharmacology 20051001
Title: A phase II study of nilutamide in men with prostate cancer after the failure of flutamide or bicalutamide therapy.
Journal: BJU international 20051001
Title: Clinical outcome of maximum androgen blockade using flutamide as second-line hormonal therapy for hormone-refractory prostate cancer.
Journal: BJU international 20051001
Title: Prostate cancer presenting with fever and rigors.
Journal: Internal medicine journal 20051001
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Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20051001
Title: Is combined androgen blockade with bicalutamide cost-effective compared with combined androgen blockade with flutamide?
Journal: Urology 20051001
Title: Insulin resistance as an adverse effect of leuprolide and bicalutamide treatment.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20051001
Title: Antiandrogens prevent stable DNA-binding of the androgen receptor.
Journal: Journal of cell science 20050915
Title: Androgen receptor signaling and vitamin D receptor action in prostate cancer cells.
Journal: The Prostate 20050901
Title: Clinical outcome of oral uracil/tegafur (UFT) therapy for patients with hormone refractory prostate cancer.
Journal: Oncology reports 20050901
Title: Effect of androgen deprivation therapy in the thyroid function test of patients with prostate cancer.
Journal: Anti-cancer drugs 20050901
Title: Clinical outcomes of androgen deprivation as the sole therapy for localized and locally advanced prostate cancer.
Journal: BJU international 20050901
Title: Late radiotherapy toxicity after prostate cancer treatment: influence of hormonal therapy.
Journal: Urology 20050901
Title: Radiotherapeutic prophylaxis of gynecomastia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050820
Title: Androgen receptor regulates Cdc6 in synchronized LNCaP cells progressing from G1 to S phase.
Journal: Journal of cellular physiology 20050801
Title: Phosphorylation status of Fas-associated death domain-containing protein (FADD) is associated with prostate cancer progression.
Journal: The Journal of pathology 20050801
Title: The cost-effectiveness of combined androgen blockade with bicalutamide and luteinizing hormone releasing hormone agonist in men with metastatic prostate cancer.
Journal: The Journal of urology 20050801
Title: The experiences of men receiving androgen deprivation treatment for prostate cancer: a qualitative study.
Journal: The Canadian journal of urology 20050801
Title: The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20050712
Title: Additive antitumor effects of the epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib (Iressa), and the nonsteroidal antiandrogen, bicalutamide (Casodex), in prostate cancer cells in vitro.
Journal: International journal of cancer 20050701
Title: Bicalutamide ('Casodex') 150 mg as adjuvant to radiotherapy in patients with localised or locally advanced prostate cancer: results from the randomised Early Prostate Cancer Programme.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050701
Title: The impact of hormone therapy on post-implant dosimetry and outcome following Iodine-125 implant monotherapy for localised prostate cancer.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050601
Title: An interdisciplinary approach to treating prostate cancer.
Journal: Urology 20050601
Title: Treating the biochemical recurrence of prostate cancer after definitive primary therapy.
Journal: Clinical prostate cancer 20050601
Title: Locally advanced prostate cancer treated with radiotherapy and androgen deprivation.
Journal: Nature clinical practice. Urology 20050601
Title: 5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells.
Journal: The Prostate 20050515
Title: Induction of AP-1 activity by androgen activation of the androgen receptor in LNCaP human prostate carcinoma cells.
Journal: The Prostate 20050501
Title: Biochemical recurrence after definitive prostate cancer therapy. Part II: treatment strategies for biochemical recurrence of prostate cancer.
Journal: Current opinion in urology 20050501
Title: Preventing bone loss during androgen deprivation therapy for prostate cancer: early experience with neridronate.
Journal: European urology 20050501
Title: Efficacy and tolerability of radiotherapy as treatment for bicalutamide-induced gynaecomastia and breast pain in prostate cancer.
Journal: European urology 20050501
Title: Efficacy of tamoxifen and radiotherapy for prevention and treatment of gynaecomastia and breast pain caused by bicalutamide in prostate cancer: a randomised controlled trial.
Journal: The Lancet. Oncology 20050501
Title: [Reevaluation of MAB therapy and progress of endocrine therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050501
Title: Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
Journal: Journal of medicinal chemistry 20050421
Title: A case of male breast cancer in association with bicalutamide-induced gynaecomastia.
Journal: Breast (Edinburgh, Scotland) 20050401
Title: Reversibility of androgen deprivation therapy in patients with prostate cancer.
Journal: The Journal of urology 20050301
Title: Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells.
Journal: Cancer research 20050301
Title: Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
Journal: Endocrine-related cancer 20050301
Title: Successful recovery from interstitial pneumonitis, induced by bicalutamide and leuprorelin acetate given as treatment for prostate cancer.
Journal: Hinyokika kiyo. Acta urologica Japonica 20050301
Title: Combined androgen blockade: the case for bicalutamide.
Journal: Clinical prostate cancer 20050301
Title: Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain.
Journal: Journal of medicinal chemistry 20050224
Title: Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050201
Title: Comparison of microvessel densities in rat prostate tissues treated with finasteride, bicalutamide and surgical castration: a preliminary study.
Journal: International journal of urology : official journal of the Japanese Urological Association 20050201
Title: Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20050117
Title: Identification of a novel class of androgen receptor antagonists based on the bicyclic-1H-isoindole-1,3(2H)-dione nucleus.
Journal: Bioorganic & medicinal chemistry letters 20050117
Title: Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines.
Journal: The Journal of pharmacy and pharmacology 20050101
Title: Approach to management of clinically localized prostate cancer in patients with human immunodeficiency virus.
Journal: Urology 20050101
Title: [Correlation between re-biopsy one year after endocrine therapy and long-term prognosis in localized prostate cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050101
Title: Randomized controlled trial to evaluate radiotherapy +/- endocrine therapy versus endocrine therapy alone for PSA failure after radical prostatectomy: Japan Clinical Oncology Group Study JCOG 0401.
Journal: Japanese journal of clinical oncology 20050101
Title: Prevention and management of bicalutamide-induced gynecomastia and breast pain: randomized endocrinologic and clinical studies with tamoxifen and anastrozole.
Journal: Prostate cancer and prostatic diseases 20050101
Title: Bicalutamide vs cyproterone acetate in preventing flare with LHRH analogue therapy for prostate cancer--a pilot study.
Journal: Prostate cancer and prostatic diseases 20050101
Title: Prolonged response to nilutamide in a patient with stage D0.5 prostate cancer who previously failed androgen deprivation therapy.
Journal: American journal of therapeutics 20050101
Title: Casodex treatment induces hypoxia-related gene expression in the LNCaP prostate cancer progression model.
Journal: BMC urology 20050101
Title: Comparative effects of bicalutamide (Casodex) versus orchidectomy on bone mineral density, bone remodelling, and bone biomechanics in healthy rats.
Journal: Urologia internationalis 20050101
Title: Bicalutamide ('Casodex') 150 mg in addition to standard care in patients with nonmetastatic prostate cancer: updated results from a randomised double-blind phase III study (median follow-up 5.1 y) in the early prostate cancer programme.
Journal: Prostate cancer and prostatic diseases 20050101
Title: Case study: management of advanced prostate cancer with soft tissue metastases.
Journal: Prostate cancer and prostatic diseases 20050101
Title: Case study: management of lymph node-positive disease detected at radical prostatectomy.
Journal: Prostate cancer and prostatic diseases 20050101
Title: Impact of hormone therapy on acute radiotherapy toxicity in the treatment of prostate cancer.
Journal: Prostate cancer and prostatic diseases 20050101
Title: Behavior of free testosterone in patients with prostate cancer on androgen deprivation therapy.
Journal: The International journal of biological markers 20050101
Title: Proptosis and decreased vision secondary to prostate cancer orbital wall metastasis.
Journal: Anticancer research 20050101
Title: Diethylstilboestrol versus bicalutamide in hormone refractory prostate carcinoma: a prospective randomized trial.
Journal: Urologia internationalis 20050101
Title: 4-OH tamoxifen does not interfere with bicalutamide inhibitory effects on human prostatic cancer cells in vitro.
Journal: Anticancer research 20050101
Title: Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor.
Journal: Molecular endocrinology (Baltimore, Md.) 20041101
Title: Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041101
Title: Bicalutamide 150 mg in addition to standard care in patients with localized or locally advanced prostate cancer: results from the second analysis of the early prostate cancer program at median followup of 5.4 years.
Journal: The Journal of urology 20041101
Title: Bicalutamide (150 mg) versus placebo as immediate therapy alone or as adjuvant to therapy with curative intent for early nonmetastatic prostate cancer: 5.3-year median followup from the Scandinavian Prostate Cancer Group Study Number 6.
Journal: The Journal of urology 20041101
Title: The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer.
Journal: The Journal of pathology 20041001
Title: Prophylactic breast irradiation with a single dose of electron beam radiotherapy (10 Gy) significantly reduces the incidence of bicalutamide-induced gynecomastia.
Journal: International journal of radiation oncology, biology, physics 20041001
Title: Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.
Journal: Cancer research 20041001
Title: Effects of testosterone, dihydrotestosterone, and 17beta-estradiol on human ovarian tissue survival in culture.
Journal: Fertility and sterility 20041001
Title: Bicalutamide 150 mg: practical prescribing in patients with early prostate cancer.
Journal: BJU international 20041001
Title: Unexpected response of hormone-refractory prostate cancer to treatment with an antileukemic chemotherapy regimen.
Journal: Urology 20041001
Title: Monotherapy in advanced prostate cancer: an overview.
Journal: Experimental oncology 20040901
Title: Osteoporosis and spinal fractures in men with prostate cancer: risk factors and effects of androgen deprivation therapy.
Journal: The Journal of urology 20040801
Title: Re: The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer.
Journal: The Journal of urology 20040801
Title: The 3rd Conference on Asian Trends in Prostate Cancer Hormone Therapy.
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040801
Title: Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol.
Journal: The Journal of steroid biochemistry and molecular biology 20040801
Title: A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.
Journal: Journal of medicinal chemistry 20040715
Title: Bicalutamide monotherapy versus leuprolide monotherapy for prostate cancer: effects on bone mineral density and body composition.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040701
Title: Bicalutamide 150 mg maintains bone mineral density during monotherapy for localized or locally advanced prostate cancer.
Journal: The Journal of urology 20040601
Title: Regulation of matrix metalloproteinase 13 expression by androgen in prostate cancer.
Journal: Oncology reports 20040601
Title: The biological basis for the use of an anti-androgen and a 5-alpha-reductase inhibitor in the treatment of recurrent prostate cancer: Case report and review.
Journal: Oncology reports 20040601
Title: Finasteride and bicalutamide as primary hormonal therapy in patients with advanced adenocarcinoma of the prostate.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20040601
Title: Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells.
Journal: Journal of molecular endocrinology 20040601
Title: Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells.
Journal: Endocrinology 20040501
Title: Re: See W, Iversen P, Wirth M, McLeod D, Garside L, Morris T. Immediate treatment with bicalutamide 150 mg as adjuvant therapy significantly reduces the risk of PSA progression in early prostatic cancer. Eur Urol 2003;44:512-8.
Journal: European urology 20040501
Title: Is the efficacy of hormonal therapy affected by lymph node status? data from the bicalutamide (Casodex) Early Prostate Cancer program.
Journal: Urology 20040501
Title: Androgen signaling is required for the vitamin D-mediated growth inhibition in human prostate cancer cells.
Journal: Oncogene 20040422
Title: Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells.
Journal: The Journal of biological chemistry 20040409
Title: Effect of nonsteroidal antiandrogen monotherapy versus castration therapy on neuroendocrine differentiation in prostate carcinoma.
Journal: Urology 20040301
Title: An evaluation of bicalutamide in the treatment of prostate cancer.
Journal: Clinical prostate cancer 20040301
Title: Alternative antiandrogens to treat prostate cancer relapse after initial hormone therapy.
Journal: The Journal of urology 20040201
Title: Bicalutamide (Casodex) in the treatment of prostate cancer.
Journal: Expert review of anticancer therapy 20040201
Title: [A case of seminal vesicle cyst due to the obstruction of the ejaculatory duct: possible association with prostate cancer].
Journal: Hinyokika kiyo. Acta urologica Japonica 20040201
Title: Androgen ablation therapy for prostate carcinoma suppresses the immunoreactive telomerase subunit hTERT.
Journal: Cancer 20040115
Title: Prognosis of stage pT0 after prolonged neoadjuvant endocrine therapy of prostate cancer: a matched-pair analysis.
Journal: European urology 20040101
Title: Antiandrogen monotherapy: recommendations for the treatment of prostate cancer.
Journal: Urologia internationalis 20040101
Title: Superior anti-tumor efficacy of bicalutamide 80 mg in combination with a luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist monotherapy as first-line treatment for advanced prostate cancer: interim results of a randomized study in Japanese patients.
Journal: Japanese journal of clinical oncology 20040101
Title: High-dose radiotherapy plus prolonged hormone therapy in CT2-3 prostatic carcinoma: is it useful?
Journal: Tumori 20040101
Title: Cost-effectiveness analysis of bicalutamide (Casodex) for adjuvant treatment of early prostate cancer.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20040101
Title: [Neoadjuvant hormone therapy with casodex in a dose 150 mg prior to radical prostatectomy in patients with prostatic cancer].
Journal: Urologiia (Moscow, Russia : 1999) 20040101
Title: Bicalutamide: clinical pharmacokinetics and metabolism.
Journal: Clinical pharmacokinetics 20040101
Title: Serum C-reactive protein (CRP) levels and insulin resistance in non-obese women with polycystic ovarian syndrome, and effect of bicalutamide on hirsutism, CRP levels and insulin resistance.
Journal: Hormone research 20040101
Title: Synergic effects of the cyclin-dependent kinase (CDK) inhibitor olomoucine and androgen-antagonist bicalutamide on prostatic cancer cell lines.
Journal: Neoplasma 20040101
Title: Which patients with prostate cancer are actually candidates for hormone therapy?
Journal: International braz j urol : official journal of the Brazilian Society of Urology 20040101
Title: Hormonal therapy options for patients with a rising prostate-specific antigen level after primary treatment for prostate cancer.
Journal: Urology 20031229
Title: Nucleophilic aromatic substitution of methacrylamide anion and its application to the synthesis of the anticancer drug bicalutamide.
Journal: The Journal of organic chemistry 20031226
Title: Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031201
Title: Bicalutamide monotherapy for early stage prostate cancer: an update.
Journal: The Journal of urology 20031201
Title: Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway.
Journal: Endocrinology 20031101
Title: Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines.
Journal: The Journal of urology 20031101
Title: Intermittent maximal androgen blockade in patients with metastatic prostate cancer: an EORTC feasibility study.
Journal: European urology 20031101
Title: Immediate treatment with bicalutamide 150mg as adjuvant therapy significantly reduces the risk of PSA progression in early prostate cancer.
Journal: European urology 20031101
Title: Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer.
Journal: Cancer research 20031101
Title: Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate.
Journal: Urology 20031101
Title: Interstitial pneumonitis induced by bicalutamide and leuprorelin acetate for prostate cancer.
Journal: International journal of urology : official journal of the Japanese Urological Association 20031101
Title: Isolation and identification of L-dopa decarboxylase as a protein that binds to and enhances transcriptional activity of the androgen receptor using the repressed transactivator yeast two-hybrid system.
Journal: The Biochemical journal 20031015
Title: The role of anti-androgen monotherapy in the treatment of prostate cancer.
Journal: BJU international 20031001
Title: [Comparative study of the effect of complete prolonged neoadjuvant hormonal blockade versus standard hormonal blockade].
Journal: Actas urologicas espanolas 20031001
Title: Enhanced androgen receptor signaling correlates with the androgen-refractory growth in a newly established MDA PCa 2b-hr human prostate cancer cell subline.
Journal: Cancer research 20030901
Title: Is bicalutamide equivalent to goserelin for prostate volume reduction before radiation therapy? A prospective, observational study.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20030901
Title: The clinical rationale for immediate androgen deprivation without estrogen deprivation.
Journal: Clinical prostate cancer 20030901
Title: Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis.
Journal: Oncogene 20030828
Title: A complete remission with androgen-deprivation therapy in a recurrent androgen receptor-expressing adenocarcinoma of the parotid gland.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20030801
Title: Gene expression changes following androgen receptor elimination in LNCaP prostate cancer cells.
Journal: Molecular carcinogenesis 20030801
Title: Impact of hormone therapy when combined with external beam radiotherapy for early-stage, intermediate-, or high-risk prostate cancer.
Journal: American journal of clinical oncology 20030801
Title: UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701
Title: Antiandrogen-induced cell death in LNCaP human prostate cancer cells.
Journal: Cell death and differentiation 20030701
Title: Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells.
Journal: The Journal of biological chemistry 20030606
Title: Management of treatment-related osteoporosis in men with prostate cancer.
Journal: Cancer treatment reviews 20030601
Title: Neoadjuvant doxil chemotherapy prior to androgen ablation plus radiotherapy for high-risk localized prostate cancer: feasibility and toxicity.
Journal: American journal of clinical oncology 20030601
Title: [Effect of bicalutamide 150 mg, after 3 years of median follow-up, in non-metastatic prostatic cancer].
Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20030601
Title: The non-steroidal antiandrogen, bicalutamide ('Casodex'), may preserve bone mineral density as compared with castration: results of a preliminary study.
Journal: World journal of urology 20030501
Title: [A case of locally advanced prostate cancer with low serum testosterone associated with intake of an androgenic medicine].
Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20030501
Title: Inhibition of fatty acid synthase expression by 1alpha,25-dihydroxyvitamin D3 in prostate cancer cells.
Journal: The Journal of steroid biochemistry and molecular biology 20030501
Title: Bioassay of steroid hormone agonist and antagonist activities of anti-androgens on mammary gland, seminal vesicles and spleen of male mice.
Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20030501
Title: Store-operated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1.
Journal: The Journal of biological chemistry 20030425
Title: Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells.
Journal: Cancer research 20030415
Title: Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells.
Journal: Cancer research 20030415
Title: Bicalutamide as immediate therapy either alone or as adjuvant to standard care of patients with localized or locally advanced prostate cancer: first analysis of the Early Prostate Cancer Program.
Journal: BJU international 20030401
Title: Newer approaches to androgen deprivation therapy in prostate cancer.
Journal: Urology 20030401
Title: Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy.
Journal: Cancer 20030301
Title: The role of antiandrogen monotherapy in the treatment of prostate cancer.
Journal: BJU international 20030301
Title: Diagnosis and management of treatment-related osteoporosis in men with prostate carcinoma.
Journal: Cancer 20030201
Title: A longer duration of neo-adjuvant combined androgen blockade prior to radical prostatectomy may lead to lower tumour volume of localised prostate cancer.
Journal: European urology 20030201
Title: Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.
Journal: Molecular pharmacology 20030101
Title: Tissue polypeptide-specific antigen (TPS) determinations before and during intermittent maximal androgen blockade in patients with metastatic prostatic carcinoma.
Journal: European urology 20030101
Title: Novel mutations of androgen receptor: a possible mechanism of bicalutamide withdrawal syndrome.
Journal: Cancer research 20030101
Title: [First line therapy in the treatment of metastatic prostate cancer].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030101
Title: Cross-sectional study of bone turnover during bicalutamide monotherapy for prostate cancer.
Journal: Urology 20030101
Title: Immediate or deferred hormonal therapy?
Journal: Scandinavian journal of urology and nephrology. Supplementum 20030101
Title: Adjuvant hormonal treatment for prostate cancer: the bicalutamide early prostate cancer program.
Journal: Oncology 20030101
Title: Biochemical recurrence of prostate cancer.
Journal: Current problems in cancer 20030101
Title: Elevated E-cadherin and alpha/beta-catenin expression after androgen deprivation therapy in prostate adenocarcinoma.
Journal: Pathology, research and practice 20030101
Title: Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex.
Journal: The Journal of biological chemistry 20021213
Title: Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021201
Title: [Antiandrogen in prostate cancer].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201
Title: [Total androgen blockade].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201
Title: Induction of invasive phenotype by Casodex in hormone-sensitive prostate cancer cells.
Journal: The Journal of steroid biochemistry and molecular biology 20021201
Title: Bicalutamide monotherapy versus flutamide plus goserelin in prostate cancer: updated results of a multicentric trial.
Journal: European urology 20021101
Title: Unusual anti-angiogenic effect of combined hormonal blockade.
Journal: The Journal of urology 20021001
Title: Pneumonitis associated with nonsteroidal antiandrogens: presumptive evidence of a class effect.
Journal: Annals of internal medicine 20021001
Title: An evaluation of bicalutamide in the treatment of prostate cancer.
Journal: Expert opinion on pharmacotherapy 20020901
Title: Emerging role of adjuvant hormonal therapy.
Journal: Urology 20020901
Title: Antiandrogen monotherapy: indications and results.
Journal: Urology 20020901
Title: Osteoporosis during androgen deprivation therapy for prostate cancer.
Journal: Urology 20020901
Title: Secondary hormonal therapies in the treatment of prostate cancer.
Journal: Urology 20020901
Title: Androgen receptor as a target in androgen-independent prostate cancer.
Journal: Urology 20020901
Title: A randomised comparison of bicalutamide ('Casodex') 150 mg versus placebo as immediate therapy either alone or as adjuvant to standard care for early non-metastatic prostate cancer. First report from the Scandinavian Prostatic Cancer Group Study No. 6.
Journal: European urology 20020901
Title: Tolerability assessment of maximal androgen blockade with 50 mg daily of bicalutamide and castration in patients with advanced prostate cancer.
Journal: Chang Gung medical journal 20020901
Title: Highlights from the 97th Annual Meeting of the American Urological Association: Orlando, Florida, May 25-30, 2002.
Journal: Clinical prostate cancer 20020901
Title: Bicalutamide as immediate therapy either alone or as adjuvant to standard care of patients with localized or locally advanced prostate cancer: first analysis of the early prostate cancer program.
Journal: The Journal of urology 20020801
Title: Regulation of FGF8 expression by the androgen receptor in human prostate cancer.
Journal: Oncogene 20020801
Title: Novel nonsteroidal ligands with high binding affinity and potent functional activity for the androgen receptor.
Journal: European journal of medicinal chemistry 20020801
Title: Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor.
Journal: The Journal of biological chemistry 20020719
Title: Pure antiandrogens disrupt the recruitment of coactivator GRIP1 to colocalize with androgen receptor in nuclei.
Journal: FEBS letters 20020717
Title: Effects of complete androgen blockade for 12 and 24 weeks on the pathological stage and resection margin status of prostate cancer.
Journal: Journal of clinical pathology 20020701
Title: Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020701
Title: Stabilization of androgen receptor protein is induced by agonist, not by antagonists.
Journal: Biochemical and biophysical research communications 20020621
Title: A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer.
Journal: Endocrinology 20020501
Title: AR possesses an intrinsic hormone-independent transcriptional activity.
Journal: Molecular endocrinology (Baltimore, Md.) 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: A phase 3, multicenter, open label, randomized study of abarelix versus leuprolide plus daily antiandrogen in men with prostate cancer.
Journal: The Journal of urology 20020401
Title: The amino terminus of the human AR is target for corepressor action and antihormone agonism.
Journal: Molecular endocrinology (Baltimore, Md.) 20020401
Title: [The role of bicalutamide in the treatment of prostate cancer].
Journal: Harefuah 20020401
Title: Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways.
Journal: The Journal of biological chemistry 20020301
Title: [Adjuvant treatment of prostatic carcinoma after primary therapy. The 'Early Prostate Cancer' Program].
Journal: Recenti progressi in medicina 20020301
Title: [Adjuvant hormone therapy in prostatic cancer: after treatment with curative intent. The viewpoint of the urologist].
Journal: Recenti progressi in medicina 20020301
Title: [Efficacy of bicalutamide in adjuvant treatment of prostatic carcinoma after primary therapy with curative aim. The viewpoint of the surgeon].
Journal: Recenti progressi in medicina 20020301
Title: Bone alkaline phosphatase serum level predicts the response to antiandrogen withdrawal.
Journal: European urology 20020301
Title: AIbZIP, a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up-regulated by androgens in LNCaP human prostate cancer cells.
Journal: Cancer research 20020201
Title: Normalization of serum testosterone levels in patients treated with neoadjuvant hormonal therapy and three-dimensional conformal radiotherapy for prostate cancer.
Journal: International journal of radiation oncology, biology, physics 20020201
Title: Effect of bicalutamide therapy on prolactin response to L-dopa in metastatic prostate cancer patients.
Journal: Neuro endocrinology letters 20020201
Title: New alternative treatment in hirsutism: bicalutamide 25 mg/day.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020201
Title: Low serum testosterone level predicts worse response to endocrine therapy in Japanese patients with metastatic prostate cancer.
Journal: Endocrine journal 20020201
Title: Role of cadmium in the regulation of AR gene expression and activity.
Journal: Endocrinology 20020101
Title: Antiandrogens in the treatment of priapism.
Journal: Urology 20020101
Title: Comparative study of pressure-flow parameters.
Journal: Neurourology and urodynamics 20020101
Title: Prostate-specific antigen dynamics predict risk of progression in advanced prostate cancer treated with bicalutamide plus castration.
Journal: Urologia internationalis 20020101
Title: [Monotherapy with casodex at a dose of 150 mg--a new method of hormonal treatment of disseminated prostatic cancer].
Journal: Urologiia (Moscow, Russia : 1999) 20020101
Title: Bicalutamide: in early-stage prostate cancer.
Journal: Drugs 20020101
Title: Bicalutamide dose-dependently inhibits proliferation in human prostatic carcinoma cell lines and primary cultures.
Journal: Anticancer research 20020101
Title: Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss.
Journal: Prostate cancer and prostatic diseases 20020101
Title: Androgen receptor alterations in prostate cancer relapsed during a combined androgen blockade by orchiectomy and bicalutamide.
Journal: Laboratory investigation; a journal of technical methods and pathology 20011201
Title: Effect of an EGF-R selective tyrosine kinase inhibitor and an anti-androgen on LNCaP cells: identification of divergent growth regulatory pathways.
Journal: The Prostate 20010915
Title: Prostate cancer in the older man.
Journal: Oncology (Williston Park, N.Y.) 20010901
Title: Bicalutamide (Casodex) 150 mg as immediate therapy in patients with localized or locally advanced prostate cancer significantly reduces the risk of disease progression.
Journal: Urology 20010801
Title: Antiandrogen monotherapy: a new form of treatment for patients with prostate cancer.
Journal: Urology 20010801
Title: [Intermittent androgen deprivation treatment of prostate cancer restarted at low level of serum prostate specific antigen: a pilot study].
Journal: Hinyokika kiyo. Acta urologica Japonica 20010801
Title: Docetaxel followed by hormone therapy after failure of definitive treatments for clinically localized/locally advanced prostate cancer: preliminary results.
Journal: Seminars in oncology 20010801
Title: Phase II trial of bicalutamide in patients with advanced prostate cancer in whom conventional hormonal therapy failed: a Southwest Oncology Group study (SWOG 9235).
Journal: Urology 20010701
Title: Why phase III trials of maximal androgen blockade versus castration in M1 prostate cancer rarely show statistically significant differences.
Journal: The Prostate 20010615
Title: Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010601
Title: New drug for prostate cancer.
Journal: European journal of cancer care 20010601
Title: Prostate-specific antigen-all that rises is not refractory.
Journal: Urology 20010501
Title: CaT1 expression correlates with tumor grade in prostate cancer.
Journal: Biochemical and biophysical research communications 20010406
Title: The effect of bicalutamide on prostate histology.
Journal: The Prostate 20010301
Title: Long-term exposure of tumor necrosis factor alpha causes hypersensitivity to androgen and anti-androgen withdrawal phenomenon in LNCaP prostate cancer cells.
Journal: The Prostate 20010301
Title: Effects of long-term treatment with the anti-androgen bicalutamide on human testis: an ultrastructural and morphometric study.
Journal: Histopathology 20010301
Title: Cross-talk between steroid-receptor-mediated and cell-membrane-receptor-mediated signalling pathways results in the in vivo modulation of c-Met and ornithine decarboxylase gene expression in mouse kidney.
Journal: The Biochemical journal 20010115
Title: Treatment of locally advanced prostate cancer--a new role for antiandrogen monotherapy?
Journal: European urology 20010101
Title: Nonsteroidal antiandrogens: a therapeutic option for patients with advanced prostate cancer who wish to retain sexual interest and function.
Journal: BJU international 20010101
Title: Levels of alpha 2 macroglobulin can predict bone metastases in prostate cancer.
Journal: Anticancer research 20010101
Title: Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients.
Journal: The oncologist 20010101
Title: Ultrastructural and quantitative immunohistochemical changes induced by nonsteroid antiandrogens on pituitary gonadotroph population of prepubertal male rats.
Journal: Cells, tissues, organs 20010101
Title: [Bicalutamide monotherapy of patients with disseminated forms of prostatic cancer].
Journal: Urologiia (Moscow, Russia : 1999) 20010101
Title: [Changes in prostate-specific antigen in casodex (bicalutamide) monotherapy in a dose 150 mg/day given to patients with locally advanced and/or advanced prostatic cancer].
Journal: Urologiia (Moscow, Russia : 1999) 20010101
Title: Delaying/reducing the risk of clinical tumour progression after primary curative procedures.
Journal: European urology 20010101
Title: Neither fibroblast growth factor-1 nor fibroblast growth factor-2 is an androgen receptor coactivator in androgen-resistant prostate cancer.
Journal: Molecular urology 20010101
Title: [Preliminary results of casodex use in patients with hormone-resistant cancer of the prostate].
Journal: Urologiia (Moscow, Russia : 1999) 20010101
Title: Androgen sensitivity related proteins in hormone-sensitive and hormone-insensitive prostate cancer cell lines treated by androgen antagonist bicalutamide.
Journal: Neoplasma 20010101
Title: Antiandrogen withdrawal syndrome associated with prostate cancer therapies: incidence and clinical significance.
Journal: Drug safety 20001101
Title: Ligand-independent activation of the androgen receptor by the differentiation agent butyrate in human prostate cancer cells.
Journal: Cancer research 20001015
Title: 1alpha,25-dihydroxyvitamin D3 inhibits prostate cancer cell growth by androgen-dependent and androgen-independent mechanisms.
Journal: Endocrinology 20000701
Title: Bicalutamide (Casodex)-induced prostate regression involves increased expression of genes encoding insulin-like growth factor binding proteins.
Journal: Urology 19991201
Title: Regulation of GCDFP-15 expression in human mammary cancer cells.
Journal: International journal of molecular medicine 19990801
Title: Rapid and sensitive reporter gene assays for detection of antiandrogenic and estrogenic effects of environmental chemicals.
Journal: Toxicology and applied pharmacology 19990301
Title: Synthesis and biological activity of a novel series of nonsteroidal, peripherally selective androgen receptor antagonists derived from 1,2-dihydropyridono[5,6-g]quinolines.
Journal: Journal of medicinal chemistry 19980212
Title: A five-alpha reductase inhibitor or an antiandrogen prevents the progression of microscopic prostate carcinoma to macroscopic carcinoma in rats.
Journal: Cancer 19980201
Title: 1alpha,25-dihydroxyvitamin D3 actions in LNCaP human prostate cancer cells are androgen-dependent.
Journal: Endocrinology 19970801
Title: Comparison of in vitro effects of the pure antiandrogens OH-flutamide, Casodex, and nilutamide on androgen-sensitive parameters.
Journal: Urology 19970401
Title: Nicola J. Clegg,1 John Wongvipat,1,2 Jim Joseph, ARN-509: a novel anti-androgen for prostate cancer treatment. Cancer Res. 2012 March 15; 72(6): 1494-1503.
