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905105-89-7,MFCD12195834
Catalog No.:AA00H082

905105-89-7 | TMCB

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10mg
≥98%
in stock  
$254.00   $178.00
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50mg
≥98%
in stock  
$870.00   $609.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00H082
Chemical Name:
TMCB
CAS Number:
905105-89-7
Molecular Formula:
C11H9Br4N3O2
Molecular Weight:
534.8241
MDL Number:
MFCD12195834
SMILES:
OC(=O)Cn1c(nc2c1c(Br)c(Br)c(c2Br)Br)N(C)C
Properties
Computed Properties
 
Complexity:
387  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
4.4  

Literature

Title: Modified tetrahalogenated benzimidazoles with CK2 inhibitory activity are active against human prostate cancer cells LNCaP in vitro.

Journal: Bioorganic & medicinal chemistry 20120715

Title: CK2α and CK2α' subunits differ in their sensitivity to 4,5,6,7-tetrabromo- and 4,5,6,7-tetraiodo-1H-benzimidazole derivatives.

Journal: European journal of medicinal chemistry 20120101

Title: Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated by inhibition of SK channels.

Journal: Neuron 20101209

Title: The selectivity of inhibitors of protein kinase CK2: an update.

Journal: The Biochemical journal 20081101

Title: Bollacke A, Nienberg C, Borgne ML, Jose J. Toward selective CK2alpha and CK2alpha' inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha'. J Pharm Biomed Anal. 2016;121:253-260.

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