Home Imidazoles 91-75-8
91-75-8,MFCD00047013
Catalog No.:AA006PKZ

91-75-8 | N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$93.00   $65.00
- +
10mg
98%
in stock  
$113.00   $79.00
- +
25mg
98%
in stock  
$165.00   $115.00
- +
50mg
98%
in stock  
$220.00   $154.00
- +
100mg
98%
in stock  
$307.00   $215.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA006PKZ
Chemical Name:
N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline
CAS Number:
91-75-8
Molecular Formula:
C17H19N3
Molecular Weight:
265.3529
MDL Number:
MFCD00047013
SMILES:
c1ccc(cc1)CN(c1ccccc1)CC1=NCCN1
Properties
Properties
 
BP:
475.5°C at 760 mmHg  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
314  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
2.6  

Downstream Synthesis Route

[1]CurrentPatentAssignee:CIBAPHARMACEUTICALPRODUCTS,INC.-US2505133,1945,A

[1]HelveticaChimicaActa,1950,vol.33,p.1386,1403

[1]Ruckmick;Marsh;Duong[JournalofPharmaceuticalSciences,1995,vol.84,#4,p.502-507]

[2]Miescheretal.[HelveticaChimicaActa,1951,vol.34,p.1,16]

[3]Berzi,Karlis;Grante,Ilze;Nakurte,Ilva;Acti,Andris[RSCAdvances,2015,vol.5,#83,p.68179-68186]

CASUnavailable 
  91-75-8 

[1]CurrentPatentAssignee:SANOFI-DE830954,1951,C[DRP/DRBPOrg.Chem.][DRP/DRBPOrg.Chem.]

[1]Dash;Kudav;Parihar[JournalofHeterocyclicChemistry,2006,vol.43,#2,p.401-404]

[2]CurrentPatentAssignee:NOVARTISAG;Novartis(w/oSandoz)-DE847746,1948,CCurrentPatentAssignee:CIBAPHARMACEUTICALPRODUCTS,INC.-US2505248,1945,A

Literature

Title: A randomized controlled trial of intralesional bevacizumab injection on primary pterygium: preliminary results.

Journal: Cornea 20111101

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: Modulation of metabolic activity of phagocytes by antihistamines.

Journal: Interdisciplinary toxicology 20110301

Title: New imidazoline/α(2)-adrenoceptors affecting compounds-4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies.

Journal: Bioorganic & medicinal chemistry 20110101

Title: Study and development of reversed-phase HPLC systems for the determination of 2-imidazolines in the presence of preservatives in pharmaceutical preparations.

Journal: Journal of AOAC International 20110101

Title: Development and validation of spectrophotometric, atomic absorption and kinetic methods for determination of moxifloxacin hydrochloride.

Journal: Analytical chemistry insights 20110101

Title: Evidence for the involvement of the noradrenergic system, dopaminergic and imidazoline receptors in the antidepressant-like effect of tramadol in mice.

Journal: Pharmacology, biochemistry, and behavior 20100501

Title: Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study.

Journal: European journal of ophthalmology 20100101

Title: Simultaneous determination of antazoline and naphazoline by the net analyte signal standard addition method and spectrophotometric technique.

Journal: Journal of AOAC International 20100101

Title: Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.

Journal: The Biochemical journal 20091023

Title: Demand for food and cocaine in Fischer and Lewis rats.

Journal: Behavioral neuroscience 20090201

Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Journal: Journal of medicinal chemistry 20080124

Title: [Histamine and the convulsive threshold or effectiveness of antiepileptic drugs].

Journal: Przeglad lekarski 20080101

Title: Evidence for imidazoline receptors involvement in the agmatine antidepressant-like effect in the forced swimming test.

Journal: European journal of pharmacology 20070622

Title: Net analyte signal-based simultaneous determination of antazoline and naphazoline using wavelength region selection by experimental design-neural networks.

Journal: Talanta 20060215

Title: A rapid derivative spectrophotometric method for simultaneous determination of naphazoline and antazoline in eye drops.

Journal: Chemical & pharmaceutical bulletin 20060101

Title: Effect of histamine receptor antagonists on aminophylline-induced seizures and lethality in mice.

Journal: Pharmacological reports : PR 20050101

Title: Simple HPLC determination of benzalkonium chloride in ophthalmic formulations containing antazoline and tetrahydrozoline.

Journal: PDA journal of pharmaceutical science and technology 20050101

Title: Influence of antazoline and ketotifen on the anticonvulsant activity of conventional antiepileptics against maximal electroshock in mice.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20040801

Title: The thermodynamic dissociation constants of ambroxol, antazoline, naphazoline, oxymetazoline and ranitidine by the regression analysis of spectrophotometric data.

Journal: Talanta 20040227

Title: The effects of imidazoline agents on the aggregation of human platelets.

Journal: The Journal of pharmacy and pharmacology 20040201

Title: Evaluation of the phencyclidine-like discriminative stimulus effects of novel NMDA channel blockers in rats.

Journal: Psychopharmacology 20031101

Title: Conjunctival allergen challenge: models in the investigation of ocular allergy.

Journal: Current allergy and asthma reports 20030701

Title: Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus.

Journal: Neuroscience 20030101

Title: Inhibition of voltage-gated Ca2+ channels by antazoline.

Journal: Neuroreport 20021007

Title: Interactions of ligands at angiotensin II-receptors and imidazoline receptors.

Journal: Japanese journal of pharmacology 20010201

Title: Pharmacometric analysis of alpha1-adrenoceptor function in rat tail artery pretreated with lipopolysaccharides.

Journal: Polish journal of pharmacology 20010101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:91-75-8 Molecular Formula|91-75-8 MDL|91-75-8 SMILES|91-75-8 N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline