[1]CurrentPatentAssignee:AMGENINC;USROVETOPHILIP-WO2006/116713,2006,A1Locationinpatent:Page/Pagecolumn130
[1]Liu,Longbin;Siegmund,Aaron;Xi,Ning;Kaplan-Lefko,Paula;Rex,Karen;Chen,April;Lin,Jasmine;Moriguchi,Jodi;Berry,Loren;Huang,Liyue;Teffera,Yohannes;Yang,Yajing;Zhang,Yihong;Bellon,StevenF.;Lee,Matthew;Shimanovich,Roman;Bak,Annette;Dominguez,Celia;Norman,MarkH.;Harmange,Jean-Christophe;Dussault,Isabelle;Kim,Tae-Seong[JournalofMedicinalChemistry,2008,vol.51,#13,p.3688-3691]
Title: Longbin Liu, et al. Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458). J Med Chem. 2008 Jul 10;51(13):3688-91.
