Home Amines 91674-26-9
91674-26-9,MFCD00214293
Catalog No.:AA00IGR9

91674-26-9 | (2R,3S,4R,5R)-5-Amino-2,3,4-trihydroxy-6-oxohexyl hydrogen sulfate

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10mg
≥95%
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$58.00   $40.00
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50mg
≥95%
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$253.00   $177.00
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100mg
≥95%
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$446.00   $312.00
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250mg
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IGR9
Chemical Name:
(2R,3S,4R,5R)-5-Amino-2,3,4-trihydroxy-6-oxohexyl hydrogen sulfate
CAS Number:
91674-26-9
Molecular Formula:
C6H13NO8S
Molecular Weight:
259.2343
MDL Number:
MFCD00214293
SMILES:
O=C[C@@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)O)O)O)O)N
Properties
Computed Properties
 
Complexity:
311  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
7  
XLogP3:
-6.4  

Downstream Synthesis Route
91674-26-9   
C12H14N6O2 
 
C18H25N7O9S 

[1]CurrentPatentAssignee:WHITEHEADINSTITUTEFORBIOMEDICALRESEARCH;MASSGENERALBRIGHAMINC-WO2015/73746,2015,A2Locationinpatent:Paragraph0023

Literature

Title: Substrate specificity of 6-O-endosulfatase (Sulf-2) and its implications in synthesizing anticoagulant heparan sulfate.

Journal: Glycobiology 20121001

Title: Heparan sulfate expression is affected by inflammatory stimuli in primary human endothelial cells.

Journal: Glycoconjugate journal 20120101

Title: Anti-inflammatory action of sulfated glucosamine on cytokine regulation in LPS-activated PMA-differentiated THP-1 macrophages.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20111201

Title: Anti-obesity effect of sulfated glucosamine by AMPK signal pathway in 3T3-L1 adipocytes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091001

Title: Regulation of zebrafish skeletogenesis by ext2/dackel and papst1/pinscher.

Journal: PLoS genetics 20080701

Title: Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells.

Journal: Bioorganic & medicinal chemistry 20070715

Title: Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells.

Journal: PloS one 20070101

Title: HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

Journal: BMC biochemistry 20060101

Title: Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.

Journal: Neoplasia (New York, N.Y.) 20051101

Title: The charged milieu: a major player in fertilization reactions.

Journal: Acta histochemica 20040201

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SDS
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Tags:91674-26-9 Molecular Formula|91674-26-9 MDL|91674-26-9 SMILES|91674-26-9 (2R,3S,4R,5R)-5-Amino-2,3,4-trihydroxy-6-oxohexyl hydrogen sulfate