Home Bromides 91714-93-1
91714-93-1,MFCD09953182
Catalog No.:AA01EAYD

91714-93-1 | Bromfenac Sodium

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1mg
98%
in stock  
$6.00   $4.00
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10mg
98%
in stock  
$55.00   $39.00
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50mg
98%
in stock  
$94.00   $66.00
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100mg
98%(HPLC)
in stock  
$161.00   $113.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EAYD
Chemical Name:
Bromfenac Sodium
CAS Number:
91714-93-1
Molecular Formula:
C15H11BrNNaO3
Molecular Weight:
356.1465
MDL Number:
MFCD09953182
SMILES:
[O-]C(=O)Cc1cccc(c1N)C(=O)c1ccc(cc1)Br.[Na+]
Properties
Computed Properties
 
Complexity:
372  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  

Literature

Title: Topical bromfenac as an adjunctive treatment with intravitreal ranibizumab for exudative age-related macular degeneration.

Journal: Retina (Philadelphia, Pa.) 20121001

Title: Acute corneal melt associated with topical bromfenac use.

Journal: Eye & contact lens 20120701

Title: Prospective randomized controlled trial of combination ranibizumab (Lucentis) and bromfenac (Xibrom) for neovascular age-related macular degeneration: a pilot study.

Journal: Retina (Philadelphia, Pa.) 20120301

Title: A randomized comparison of to-aqueous penetration of ketorolac 0.45%, bromfenac 0.09% and nepafenac 0.1% in cataract patients undergoing phacoemulsification.

Journal: Current medical research and opinion 20111201

Title: Prostaglandin E2 inhibition of ketorolac 0.45%, bromfenac 0.09%, and nepafenac 0.1% in patients undergoing phacoemulsification.

Journal: Advances in therapy 20111201

Title: Inflammation after phakic implants.

Journal: Ophthalmology 20111201

Title: Safety and efficacy of bromfenac ophthalmic solution (Bromday) dosed once daily for postoperative ocular inflammation and pain.

Journal: Ophthalmology 20111101

Title: NSAIDs inhibit neovascularization of choroid through HO-1-dependent pathway.

Journal: Laboratory investigation; a journal of technical methods and pathology 20110901

Title: Once daily dosing of bromfenac ophthalmic solution 0.09% for postoperative ocular inflammation and pain.

Journal: Current medical research and opinion 20110901

Title: Ocular penetration and anti-inflammatory activity of ketorolac 0.45% and bromfenac 0.09% against lipopolysaccharide-induced inflammation.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110401

Title: Pharmacokinetic comparisons of bromfenac in DuraSite and Xibrom.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110201

Title: Efficacy of bromfenac sodium ophthalmic solution in preventing cystoid macular oedema after cataract surgery in patients with diabetes.

Journal: Acta ophthalmologica 20101201

Title: Efficacy and safety of bromfenac for the treatment of corneal ulcer pain.

Journal: Advances in therapy 20101001

Title: NSAIDs in combination therapy for the treatment of chronic pseudophakic cystoid macular edema.

Journal: Retina (Philadelphia, Pa.) 20100201

Title: Ophthalmic utility of topical bromfenac, a twice-daily nonsteroidal anti-inflammatory agent.

Journal: Expert opinion on pharmacotherapy 20091001

Title: Differential effects of non-steroidal anti-inflammatory drugs on mitochondrial dysfunction during oxidative stress.

Journal: Archives of biochemistry and biophysics 20091001

Title: Vitreous nonsteroidal antiinflammatory drug concentrations and prostaglandin E2 levels in vitrectomy patients treated with ketorolac 0.4%, bromfenac 0.09%, and nepafenac 0.1%.

Journal: Retina (Philadelphia, Pa.) 20091001

Title: Efficacy of ophthalmic nonsteroidal antiinflammatory drugs in suppressing anterior capsule contraction and secondary posterior capsule opacification.

Journal: Journal of cataract and refractive surgery 20090901

Title: Concentration and dosing of ketorolac versus bromfenac.

Journal: Journal of cataract and refractive surgery 20090701

Title: Comparison of efficacy of bromfenac sodium 0.1% ophthalmic solution and fluorometholone 0.02% ophthalmic suspension for the treatment of allergic conjunctivitis.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090601

Title: Aqueous prostaglandin E(2) of cataract patients at trough ketorolac and bromfenac levels after 2 days dosing.

Journal: Advances in therapy 20090601

Title: Effect of bromfenac ophthalmic solution on ocular inflammation following cataract surgery.

Journal: Acta ophthalmologica 20090501

Title: Cyclooxygenase (COX)-inhibiting drug reduces HSV-1 reactivation in the mouse eye model.

Journal: Current eye research 20090301

Title: Topical bromfenac 0.09% vs. ketorolac 0.4% for the control of pain, photophobia, and discomfort following PRK.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20090201

Title: Retrospective review of the efficacy of topical bromfenac (0.09%) as an adjunctive therapy for patients with neovascular age-related macular degeneration.

Journal: Retina (Philadelphia, Pa.) 20090101

Title: Ocular pharmacokinetics of a single dose of bromfenac sodium ophthalmic solution 0.1% in human aqueous humor.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20081201

Title: Comparison of ketorolac 0.4% and bromfenac 0.09% at trough dosing: aqueous drug absorption and prostaglandin E2 levels.

Journal: Journal of cataract and refractive surgery 20080901

Title: Re: Pharmacokinetics and pharmacodynamics of nepafenac, amfenac, ketorolac, and bromfenac.

Journal: Journal of cataract and refractive surgery 20080801

Title: 24-hour evaluation of the ocular distribution of (14)C-labeled bromfenac following topical instillation into the eyes of New Zealand White rabbits.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080801

Title: The systemic safety of bromfenac ophthalmic solution 0.09%.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20071201

Title: Bromfenac ophthalmic solution 0.09% (Xibrom) for postoperative ocular pain and inflammation.

Journal: Ophthalmology 20070901

Title: In vivo pharmacokinetics and in vitro pharmacodynamics of nepafenac, amfenac, ketorolac, and bromfenac.

Journal: Journal of cataract and refractive surgery 20070901

Title: Corneal melting and perforation in Stevens Johnson syndrome following topical bromfenac use.

Journal: Journal of cataract and refractive surgery 20070901

Title: Effect of ophthalmic solution components on acrylic intraocular lenses.

Journal: Journal of cataract and refractive surgery 20070101

Title: Topical bromfenac sodium for long-term management of vernal keratoconjunctivitis.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20070101

Title: Effects of nonsteroidal ophthalmic drops on epithelial healing and pain in patients undergoing bilateral photorefractive keratectomy (PRK).

Journal: Advances in therapy 20070101

Title: Misuse and abuse of topically applied nonsteroidal anti-inflammatory drugs.

Journal: Cornea 20061201

Title: Three cases of corneal melting after instillation of a new nonsteroidal anti-inflammatory drug.

Journal: Cornea 20061201

Title: Hepatic disorders in patients treated with COX-2 selective inhibitors or nonselective NSAIDs: a case/noncase analysis of spontaneous reports.

Journal: Clinical therapeutics 20060801

Title: Effects of an opioid (oxycodone/paracetamol) and an NSAID (bromfenac) on driving ability, memory functioning, psychomotor performance, pupil size, and mood.

Journal: The Clinical journal of pain 20060601

Title: Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium.

Journal: Current medical research and opinion 20060601

Title: A systematic review of NSAIDs withdrawn from the market due to hepatotoxicity: lessons learned from the bromfenac experience.

Journal: Pharmacoepidemiology and drug safety 20060401

Title: Hy's law: predicting serious hepatotoxicity.

Journal: Pharmacoepidemiology and drug safety 20060401

Title: How can 'Hy's law' help the clinician?

Journal: Pharmacoepidemiology and drug safety 20060401

Title: Three cases of corneal melting after instillation of a new nonsteroidal anti-inflammatory drug.

Journal: Cornea 20060201

Title: Global experience with Xibrom (bromfenac ophthalmic solution) 0.09%: the first twice-daily ophthalmic nonsteroidal anti-inflammatory drug.

Journal: International ophthalmology clinics 20060101

Title: New drugs and dosage forms.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050501

Title: Comparison of 0.1% bromfenac sodium and 0.1% pemirolast potassium for the treatment of allergic conjunctivitis.

Journal: Japanese journal of ophthalmology 20040101

Title: Effects of nonsteroidal anti-inflammatory drugs on experimental allergic conjunctivitis in Guinea pigs.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201

Title: Drug-induced hepatotoxicity.

Journal: The New England journal of medicine 20030731

Title: Effect of non-steroidal anti-inflammatory ophthalmic solution on intraocular pressure reduction by latanoprost.

Journal: The British journal of ophthalmology 20030301

Title: Serious liver injury. Leading reason for drug removals, restrictions.

Journal: FDA consumer 20010101

Title: Structure toxicity relationships--how useful are they in predicting toxicities of new drugs?

Journal: Advances in experimental medicine and biology 20010101

Title: Bromfenac (Duract)-associated hepatic failure requiring liver transplantation.

Journal: The American journal of gastroenterology 19990801

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