Home Imidazoles 92134-98-0
92134-98-0,MFCD09029435
Catalog No.:AA006HXD

92134-98-0 | disodium (2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl phosphate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$7.00   $5.00
- +
5mg
98%
in stock  
$17.00   $12.00
- +
10mg
98%
in stock  
$28.00   $20.00
- +
25mg
98%
in stock  
$55.00   $39.00
- +
50mg
≥98%
in stock  
$63.00   $44.00
- +
100mg
≥98%
in stock  
$120.00   $84.00
- +
250mg
95%
in stock  
$128.00   $90.00
- +
1g
95%
in stock  
$344.00   $241.00
- +
5g
95%
in stock  
$1,009.00   $706.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA006HXD
Chemical Name:
disodium (2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl phosphate
CAS Number:
92134-98-0
Molecular Formula:
C16H13N2Na2O6P
Molecular Weight:
406.2375
MDL Number:
MFCD09029435
SMILES:
O=C1N(COP(=O)([O-])[O-])C(=O)NC1(c1ccccc1)c1ccccc1.[Na+].[Na+]
Properties
Properties
 
Form:
Solid  
MP:
220° (softens)  
Solubility:
H2O: ≥15mg/mL  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
536  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  

Literature

Title: Levetiracetam for busulfan-induced seizure prophylaxis in children undergoing hematopoietic stem cell transplantation.

Journal: Pediatric blood & cancer 20121001

Title: Initial EEG predicts outcomes in a trial of levetiracetam vs. fosphenytoin for seizure prevention.

Journal: Epilepsy & behavior : E&B 20120301

Title: Evaluation of intramuscular fosphenytoin vs intravenous phenytoin loading in the ED.

Journal: The American journal of emergency medicine 20111101

Title: Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus.

Journal: Seizure 20110701

Title: Video recording devices as a diagnostic aid.

Journal: The Journal of emergency medicine 20110401

Title: Advisers recommend improved labeling for phenytoin, fosphenytoin.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101215

Title: [Antiepileptic drugs in North America].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20100501

Title: Possible acute thrombocytopenia post esomeprazole and hydantoin coadministration.

Journal: Journal of pharmacy practice 20100401

Title: Persistent focal seizures after cat scratch encephalopathy.

Journal: Pediatric neurology 20100301

Title: Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation.

Journal: Epilepsy & behavior : E&B 20100201

Title: Effect of an educational initiative on physicians' use of weight-based fosphenytoin loading doses in the emergency department.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100101

Title: Blood pressure changes after intravenous fosphenytoin and levetiracetam in patients with acute cerebral symptoms.

Journal: Epilepsy research 20091201

Title: What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam?

Journal: Epilepsia 20091201

Title: Minimum requirements for approval of a drug in status epilepticus.

Journal: Epilepsia 20091201

Title: Evaluation of in vitro models for screening alkaline phosphatase-mediated bioconversion of phosphate ester prodrugs.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090701

Title: Fosphenytoin.

Journal: Expert opinion on drug metabolism & toxicology 20090601

Title: Case 3-2009: a 9-month-old boy with seizures.

Journal: The New England journal of medicine 20090409

Title: FDA: Epilepsy drugs may carry skin risks for Asians.

Journal: JAMA 20081224

Title: Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus.

Journal: Epilepsy research 20081101

Title: Fatal errors with cerebyx.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20081001

Title: Clinical trial: a dose-response study of fospropofol disodium for moderate sedation during colonoscopy.

Journal: Alimentary pharmacology & therapeutics 20080401

Title: Rotavirus-induced seizures in childhood.

Journal: Journal of child neurology 20071201

Title: Clinical pharmacology of parenteral use of antiepileptic drugs.

Journal: Epilepsia 20070101

Title: Interpretation of serum phenytoin concentrations: who would have thought that preventing and treating seizures were this challenging?

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060901

Title: Fosphenytoin may cause hemodynamically unstable bradydysrhythmias.

Journal: The Journal of emergency medicine 20060101

Title: Administer single-site 30-mL intramuscular injection?

Journal: Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20051201

Title: Treatment delay and the risk of prolonged status epilepticus.

Journal: Neurology 20051025

Title: Hyperphosphatemia due to fosphenytoin in a pediatric ESRD patient.

Journal: Pediatric nephrology (Berlin, Germany) 20050801

Title: Impact of phenytoin therapy on the skin and skin disease.

Journal: Expert opinion on drug safety 20041101

Title: Catheter occlusion from intravenous phenytoin.

Journal: Annals of emergency medicine 20041001

Title: Nurse sued when child dies from error in interpreting drug dosage.

Journal: Nursing law's Regan report 20041001

Title: Treatment of status epilepticus in children.

Journal: Pediatric annals 20040601

Title: Clinical policy: Critical issues in the evaluation and management of adult patients presenting to the emergency department with seizures.

Journal: Annals of emergency medicine 20040501

Title: Frontal lobe seizures and uveitis associated with acute human parvovirus B19 infection.

Journal: Journal of child neurology 20040401

Title: Cost-effectiveness of oral phenytoin, intravenous phenytoin, and intravenous fosphenytoin in the emergency department.

Journal: Annals of emergency medicine 20040301

Title: Fosphenytoin farewell?

Journal: Annals of emergency medicine 20040301

Title: A comparison of phenytoin-loading techniques in the emergency department.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040301

Title: Effects of fosphenytoin on nerve agent-induced status epilepticus.

Journal: Drug and chemical toxicology 20040201

Title: A comparison of central brain (cerebrospinal and extracellular fluids) and peripheral blood kinetics of phenytoin after intravenous phenytoin and fosphenytoin.

Journal: Seizure 20030901

Title: Enzyme-mediated precipitation of parent drugs from their phosphate prodrugs.

Journal: International journal of pharmaceutics 20030811

Title: Pharmacokinetics and clinical effects of phenytoin and fosphenytoin in children with severe malaria and status epilepticus.

Journal: British journal of clinical pharmacology 20030701

Title: Absorption rate limit considerations for oral phosphate prodrugs.

Journal: Pharmaceutical research 20030601

Title: New management strategies in the treatment of status epilepticus.

Journal: Mayo Clinic proceedings 20030401

Title: Intravenous fosphenytoin in acute mania.

Journal: The Journal of clinical psychiatry 20030401

Title: Fosphenytoin: clinical pharmacokinetics and comparative advantages in the acute treatment of seizures.

Journal: Clinical pharmacokinetics 20030101

Title: Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration.

Journal: British journal of clinical pharmacology 20021201

Title: Randomized evaluation of adverse events and length-of-stay with routine emergency department use of phenytoin or fosphenytoin.

Journal: Neurological research 20021201

Title: New antiepileptic drug therapies.

Journal: Neurologic clinics 20021101

Title: Hypocalcemia-like electrocardiographic changes after administration of intravenous fosphenytoin.

Journal: Mayo Clinic proceedings 20020601

Title: Pharmacology advances in the neuroscience intensive care unit.

Journal: Critical care nursing clinics of North America 20020301

Title: Subtherapeutic free phenytoin levels following fosphenytoin therapy in status epilepticus.

Journal: Neurology 20020108

Title: Pharmacokinetics of phenytoin following intravenous and intramuscular administration of fosphenytoin and phenytoin sodium in the rabbit.

Journal: European journal of drug metabolism and pharmacokinetics 20020101

Title: Inappropriate fosphenytoin use in the ED.

Journal: The American journal of emergency medicine 20010701

Title: Fosphenytoin: an intravenous option for the management of acute trigeminal neuralgia crisis.

Journal: Journal of pain and symptom management 20010601

Title: Prodrug metabolites: implications for therapeutic drug monitoring.

Journal: Clinical chemistry 20010501

Title: Glucuronidation of prodrug reactive site: isolation and characterization of oxymethylglucuronide metabolite of fosphenytoin.

Journal: Clinical chemistry 20010501

Title: Fosphenytoin in infants of extremely low birth weight.

Journal: Pediatric neurology 20010301

Title: Fosphenytoin: pharmacokinetics and tolerance of intramuscular loading doses.

Journal: Epilepsia 20010201

Title: Cardiac arrest after fast intravenous infusion of phenytoin mistaken for fosphenytoin.

Journal: Epilepsia 20010201

Title: Rapid in vitro conversion of fosphenytoin into phenytoin in sera of patients with liver disease: role of alkaline phosphatase.

Journal: Journal of clinical laboratory analysis 20010101

Title: Fosphenytoin.

Journal: Dimensions of critical care nursing : DCCN 20010101

Title: Pediatric use of intravenous and intramuscular phenytoin: lessons learned.

Journal: Journal of child neurology 19981001

Title: Pharmacology and pharmacokinetics of fosphenytoin.

Journal: Neurology 19960601

Title: Venous irritation related to intravenous administration of phenytoin versus fosphenytoin.

Journal: Pharmacotherapy 19940101

Title: Pharmacology of ACC-9653 (phenytoin prodrug).

Journal: Epilepsia 19890101

Title: Chan SA, et al. Fosphenytoin reduces hippocampal neuronal damage in rat following transient global ischemia. Acta Neurochir (Wien). 1998;140(2):175-80.

Title: Loscher W, et al. Anticonvulsant effect of fosphenytoin in amygdala-kindled rats: comparison with phenytoin. Epilepsy Res. 1998 Mar;30(1):69-76.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 92134-98-0
Tags:92134-98-0 Molecular Formula|92134-98-0 MDL|92134-98-0 SMILES|92134-98-0 disodium (2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl phosphate