Home Amines 92665-29-7
92665-29-7,MFCD00911719
Catalog No.:AA00626Q

92665-29-7 | (6S,7R)-7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-((E)-prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

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5mg
≥95% (mixture of cis and trans)
in stock  
$46.00   $32.00
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10mg
98%(HPLC)
in stock  
$61.00   $43.00
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25mg
98%(HPLC)
in stock  
$124.00   $87.00
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50mg
≥95% (mixture of cis and trans)
in stock  
$242.00   $169.00
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100mg
98%(HPLC)
in stock  
$253.00   $177.00
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1g
98%(HPLC)
in stock  
$718.00   $503.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00626Q
Chemical Name:
(6S,7R)-7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-((E)-prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number:
92665-29-7
Molecular Formula:
C18H19N3O5S
Molecular Weight:
389.4256
MDL Number:
MFCD00911719
SMILES:
C/C=C/C1=C(C(=O)O)N2[C@H](SC1)[C@@H](C2=O)NC(=O)[C@@H](c1ccc(cc1)O)N
Properties
Properties
 
Form:
Solid  
MP:
215-217℃ (dec.)  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
699  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
5  
XLogP3:
-1.4  

Literature

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology 20150518

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Acute generalized exanthematous pustulosis with severe organ dysfunction.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20090901

Title: Management of pain after tonsillectomy: a prospective, randomized clinical study.

Journal: Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 20090101

Title: The stability of cefprozil in oral suspension CEFZIL.

Journal: Acta poloniae pharmaceutica 20080101

Title: Redefining the management of pediatric tonsillopharyngitis with cefprozil.

Journal: Indian journal of pediatrics 20071201

Title: Comparative effects of single-dose ceftriaxone versus three oral antibiotic regimens on stool colonization by resistant bacilli in children.

Journal: The Pediatric infectious disease journal 20070101

Title: A rare case of hepatitis associated with cefprozil therapy.

Journal: Scandinavian journal of infectious diseases 20070101

Title: Pharmacokinetics of cefprozil in plasma and middle ear fluid: in children undergoing treatment for acute otitis media.

Journal: Paediatric drugs 20070101

Title: Pharmacodynamics of cefprozil against Haemophilus influenzae in an in vitro pharmacodynamic model.

Journal: Diagnostic microbiology and infectious disease 20061201

Title: The Bla2 beta-lactamase from the live-vaccine strain of Francisella tularensis encodes a functional protein that is only active against penicillin-class beta-lactam antibiotics.

Journal: Archives of microbiology 20060901

Title: Flow-injection chemiluminescent determination of cefprozil using Tris (2,2'-bipyridyl) ruthenium (II)-permanganate system.

Journal: Journal of pharmaceutical and biomedical analysis 20060616

Title: Adverse antibiotic-induced eruptions associated with epstein barr virus infection and showing Kikuchi-Fujimoto disease-like histology.

Journal: The American Journal of dermatopathology 20060201

Title: Fatal cephalosporin-induced acute hypersensitivity myocarditis.

Journal: Pediatric cardiology 20060101

Title: A pooled analysis of seven randomized crossover studies of the palatability of cefdinir oral suspension versus amoxicillin/clavulanate potassium, cefprozil, azithromycin, and amoxicillin in children aged 4 to 8 years.

Journal: Clinical therapeutics 20051201

Title: Resistant organisms and otitis media.

Journal: The Pediatric infectious disease journal 20050901

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Cefprozil-induced rash in infectious mononucleosis.

Journal: The Annals of pharmacotherapy 20050501

Title: Effectiveness of amoxicillin, azithromycin, cefprozil and clarithromycin in the treatment of acute otitis media in children: a population-based study.

Journal: Pharmacoepidemiology and drug safety 20050301

Title: [Assessment of therapeutic effectiveness of Cefprozil in a short 5-day course of empirical antibiotic therapy in ambulatory patients with bacterial infections of the upper respiratory tract and otitis media].

Journal: Otolaryngologia polska = The Polish otolaryngology 20050101

Title: [Cefprozil in the treatment of chronic maxillary sinusitis. Clinical and microbiological effectiveness and penetration into sinuses examination].

Journal: Otolaryngologia polska = The Polish otolaryngology 20050101

Title: Effect of antimicrobial therapy with amoxicillin and cefprozil on bacterial interference and beta-lactamase production in the adenoids.

Journal: The Annals of otology, rhinology, and laryngology 20041101

Title: HPLC method for simultaneous determination of cefprozil diastereomers in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20040921

Title: Pediatric tonsillopharyngitis--an evaluation of cefprozil in Indian patients.

Journal: Indian journal of pediatrics 20040701

Title: Efficacy and tolerability assessment of cefprozil in children with acute otitis media.

Journal: Indian journal of pediatrics 20040401

Title: [Resistance surveillance of common community respiratory pathogens isolated in China, 2002 - 2003].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20040301

Title: Comparison of trimethoprim-sulfamethoxazole, cephadroxil and cefprozil as prophylaxis for recurrent urinary tract infections in children.

Journal: Journal of chemotherapy (Florence, Italy) 20040201

Title: Penetration of cefprozil to middle ear effusion in children with chronic otitis media with effusion.

Journal: International journal of pediatric otorhinolaryngology 20030901

Title: Cefprozil: a review.

Journal: Indian journal of pediatrics 20030501

Title: [Multicenter, open clinical investigation on using cefprozil in therapy of otitis media in children].

Journal: Otolaryngologia polska = The Polish otolaryngology 20030101

Title: Open-Label, parallel-group, multicenter, randomized study of cefprozil versus erythromycin in children with group A streptococcal pharyngitis/tonsillitis.

Journal: Clinical therapeutics 20011101

Title: Five days of cefprozil versus 10 days of clarithromycin in the treatment of an acute exacerbation of chronic bronchitis.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011001

Title: Cefprozil versus high-dose amoxicillin/clavulanate in children with acute otitis media.

Journal: Clinical therapeutics 20010201

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Tags:92665-29-7 Molecular Formula|92665-29-7 MDL|92665-29-7 SMILES|92665-29-7 (6S,7R)-7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-((E)-prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid