Home Amines 93565-01-6
93565-01-6,MFCD13152261
Catalog No.:AA0061XG

93565-01-6 | N1,N4-Di(buta-2,3-dienyl)butane-1,4-diamine dihydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$53.00   $37.00
- +
10mg
97%
in stock  
$82.00   $58.00
- +
50mg
97%
in stock  
$156.00   $109.00
- +
100mg
95%
in stock  
$211.00   $148.00
- +
250mg
95%
in stock  
$344.00   $241.00
- +
1g
95%
in stock  
$843.00   $590.00
- +
5g
95%
in stock  
$2,505.00   $1,754.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0061XG
Chemical Name:
N1,N4-Di(buta-2,3-dienyl)butane-1,4-diamine dihydrochloride
CAS Number:
93565-01-6
Molecular Formula:
C12H22Cl2N2
Molecular Weight:
265.2225
MDL Number:
MFCD13152261
SMILES:
C=C=CCNCCCCNCC=C=C.Cl.Cl
Properties
Properties
 
BP:
300.7°C at 760 mmHg  
Form:
Solid  
Solubility:
H2O: soluble15mg/mL, clear  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
184  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
9  

Literature

Title: Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells.

Journal: Amino acids 20120201

Title: The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury.

Journal: American journal of physiology. Cell physiology 20100701

Title: Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes.

Journal: Journal of cellular and molecular medicine 20100601

Title: A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model.

Journal: Cancer research 20091001

Title: Cytotoxicity of spermine oxidation products to multidrug resistant melanoma M14 ADR2 cells: sensitization by the MDL 72527 lysosomotropic compound.

Journal: International journal of oncology 20090901

Title: Modulation by polyamines of apoptotic pathways triggered by procyanidins in human metastatic SW620 cells.

Journal: Cellular and molecular life sciences : CMLS 20080501

Title: Identification of a novel Cys2/His2-type zinc-finger protein as a component of a spermine-signaling pathway in tobacco.

Journal: Journal of plant physiology 20070601

Title: MDL 72527 and spermine oxidation products induce a lysosomotropic effect and mitochondrial alterations in tumour cells.

Journal: Biochemical Society transactions 20070401

Title: Inhibition of cell proliferation and induction of apoptosis by N(1),N(11)-diethylnorspermine-induced polyamine pool reduction.

Journal: Biochemical Society transactions 20070401

Title: Perturbation of polyamine metabolism and its relation to cell death in human colon cancer cells treated by 7beta-hydroxycholesterol and 7beta-hydroxysitosterol.

Journal: International journal of oncology 20061201

Title: Toxicity of enzymatic oxidation products of spermine to human melanoma cells (M14): sensitization by heat and MDL 72527.

Journal: Biochimica et biophysica acta 20061001

Title: Sensitization of human colon adenocarcinoma cells (LoVo) to reactive oxygen species by a lysosomotropic compound.

Journal: International journal of oncology 20061001

Title: Potentiation of apple procyanidin-triggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells.

Journal: International journal of oncology 20060801

Title: Interaction of bovine serum amine oxidase with the polyamine oxidase inactivator MDL 72527.

Journal: Biochemical and biophysical research communications 20060217

Title: Synergism between apple procyanidins and lysosomotropic drugs: potential in chemoprevention.

Journal: Anticancer research 20060101

Title: Cytotoxicity of the polyamine oxidase inactivator MDL 72527 to cancer cells: comparison with a saturated structural analogue.

Journal: International journal of oncology 20051201

Title: Inhibition of murine N1-acetylated polyamine oxidase by an acetylenic amine and the allenic amine, MDL 72527.

Journal: Biochemical and biophysical research communications 20050114

Title: Mouse spermine oxidase: a model of the catalytic cycle and its inhibition by N,N1-bis(2,3-butadienyl)-1,4-butanediamine.

Journal: Biochemical and biophysical research communications 20040910

Title: How important is the oxidative degradation of spermine?: minireview article.

Journal: Amino acids 20040701

Title: Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells.

Journal: The Journal of biological chemistry 20040625

Title: Contribution of spermidine to stimulation by hepatocyte growth factor in repair after damage of rabbit gastric mucosal cells in primary culture.

Journal: Biochimica et biophysica acta 20030120

Title: Detoxification of the polyamine analogue N1-ethyl-N11-[(cycloheptyl)methy]-4,8-diazaundecane (CHENSpm) by polyamine oxidase.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020501

Title: The polyamine oxidase inactivator MDL 72527.

Journal: Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20020101

Title: Cytotoxic effects of the polyamine oxidase inactivator MDL 72527 to two human colon carcinoma cell lines SW480 and SW620.

Journal: Cell biology and toxicology 20020101

Title: Role of polyamine metabolism in kainic acid excitotoxicity in organotypic hippocampal slice cultures.

Journal: Journal of neurochemistry 20011201

Title: Rapid induction of apoptosis by deregulated uptake of polyamine analogues.

Journal: The Biochemical journal 19971115

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Tags:93565-01-6 Molecular Formula|93565-01-6 MDL|93565-01-6 SMILES|93565-01-6 N1,N4-Di(buta-2,3-dienyl)butane-1,4-diamine dihydrochloride