Home Fluorides 93957-55-2
93957-55-2,MFCD00929076
Catalog No.:AA003QJL

93957-55-2 | sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$21.00   $15.00
- +
250mg
98%
in stock  
$39.00   $28.00
- +
1g
>98.0%(HPLC)(N)
in stock  
$112.00   $79.00
- +
5g
98 - 102% (Assay on anhydrous basis)
in stock  
$258.00   $180.00
- +
25g
98 - 102% (Assay on anhydrous basis)
in stock  
$843.00   $590.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003QJL
Chemical Name:
sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
CAS Number:
93957-55-2
Molecular Formula:
C24H25FNNaO4
Molecular Weight:
433.4478
MDL Number:
MFCD00929076
SMILES:
[O-]C(=O)C[C@H](C[C@H](/C=C/c1c(c2ccc(cc2)F)c2c(n1C(C)C)cccc2)O)O.[Na+]
Properties
Properties
 
Form:
Solid  
MP:
194-197 °C  
Solubility:
H2O: ≥9mg/mL  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
596  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  

Downstream Synthesis Route
aluminum(III)nitratenonahydrate 
 
magnesium(II)nitratehexahydrate 
  93957-55-2    7732-18-5   
Mg(II)/Al(III)layereddoublehydroxides-(fluvastatin)*nH2O 

[1]JournalofPhysicalChemistryB,2009,vol.113,p.15090-15100

Literature

Title: Sub-therapeutic doses of fluvastatin and valsartan are more effective than therapeutic doses in providing beneficial cardiovascular pleiotropic effects in rats: A proof of concept study.

Journal: Vascular pharmacology 20171201

Title: Drug-Induced Acute Liver Injury Within 12 Hours After Fluvastatin Therapy.

Journal: American journal of therapeutics 20160101

Title: Statins alter the hepatobiliary transport of unconjugated and conjugated bilirubin in sandwich-cultured rat hepatocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140901

Title: Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms.

Journal: The FEBS journal 20140801

Title: Statins modulate transcriptional activity of heme-oxygenase-1 promoter in NIH 3T3 Cells.

Journal: Journal of cellular biochemistry 20121101

Title: Dried blood spot analysis of an iron chelator--deferasirox and its potential application to therapeutic drug monitoring.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121015

Title: Fluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia.

Journal: Blood 20121011

Title: Statin-dependent activation of protein kinase Cδ in acute promyelocytic leukemia cells and induction of leukemic cell differentiation.

Journal: Leukemia & lymphoma 20120901

Title: Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.

Journal: Oncology reports 20120901

Title: Transcriptome analysis and in vivo activity of fluvastatin versus zoledronic acid in a murine breast cancer metastasis model.

Journal: Molecular pharmacology 20120901

Title: An open-label randomized controlled study of pegylated interferon/ribavirin combination therapy for chronic hepatitis C with versus without fluvastatin.

Journal: Journal of viral hepatitis 20120901

Title: Low-dose fluvastatin reverses the hypoxic pulmonary adventitial fibroblast phenotype in experimental pulmonary hypertension.

Journal: American journal of respiratory cell and molecular biology 20120801

Title: Chronic cough as a complication of treatment with statins: a case report.

Journal: Therapeutic advances in respiratory disease 20120801

Title: Statin inhibits hypoxia-induced endothelin-1 via accelerated degradation of HIF-1α in vascular smooth muscle cells.

Journal: Cardiovascular research 20120715

Title: Terminalia arjuna enhances baroreflex sensitivity and myocardial function in isoproterenol-induced chronic heart failure rats.

Journal: Journal of cardiovascular pharmacology and therapeutics 20120601

Title: Osteoprotegerin as a predictor of renal and cardiovascular outcomes in renal transplant recipients: follow-up data from the ALERT study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601

Title: Fluvastatin suppresses native and recombinant human P2X4 receptor function.

Journal: Purinergic signalling 20120601

Title: In vitro and in vivo susceptibility of two-drug and three-drug combinations of terbinafine, itraconazole, caspofungin, ibuprofen and fluvastatin against Pythium insidiosum.

Journal: Veterinary microbiology 20120525

Title: EPR studies on hydroxyl radical-scavenging activities of pravastatin and fluvastatin.

Journal: Molecular and cellular biochemistry 20120501

Title: Fluvastatin upregulates endothelial nitric oxide synthase activity via enhancement of its phosphorylation and expression and via an increase in tetrahydrobiopterin in vascular endothelial cells.

Journal: International journal of cardiology 20120405

Title: Fluvastatin inhibits angiotensin II-induced nuclear factor kappa B activation in renal tubular epithelial cells through the p38 MAPK pathway.

Journal: Molecular biology reports 20120401

Title: The transcription factor Krüppel homolog 1 is linked to the juvenile hormone-dependent maturation of sexual behavior in the male moth, Agrotis ipsilon.

Journal: General and comparative endocrinology 20120401

Title: The effects of low-dose fluvastatin and valsartan combination on arterial function: a randomized clinical trial.

Journal: European journal of internal medicine 20120401

Title: Risk factors for cardiovascular events in Japanese patients treated with fluvastatin from the long-term event monitoring (LEM) study.

Journal: Current vascular pharmacology 20120301

Title: Fluvastatin-induced alterations of skeletal muscle function in hypercholesterolaemic rats.

Journal: Journal of muscle research and cell motility 20120301

Title: The interaction between fluvastatin and warfarin.

Journal: International journal of cardiology 20120223

Title: Risk factor levels, risk factor combinations, and residual coronary risk: population-based estimates for secondary prevention patients using statins.

Journal: European journal of preventive cardiology 20120201

Title: The interactions of atorvastatin and fluvastatin with carbamazepine, phenytoin and valproate in the mouse maximal electroshock seizure model.

Journal: European journal of pharmacology 20120105

Title: Graft loss risk in renal transplant recipients with metabolic syndrome: subgroup analyses of the ALERT trial.

Journal: Journal of nephrology 20120101

Title: [Focal myositis as a side effect of antilipidemics - 2 patients with involvement of the forearm].

Journal: Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... 20120101

Title: Low-dose fluvastatin prevents the functional alterations of endothelium induced by short-term cholesterol feeding in rabbit carotid artery.

Journal: TheScientificWorldJournal 20120101

Title: Osteogenic effect of fluvastatin combined with biodegradable gelatin-hydrogel.

Journal: Dental materials journal 20120101

Title: Selected statins produce rapid spinal motor neuron loss in vitro.

Journal: BMC musculoskeletal disorders 20120101

Title: The difference in pharmacokinetics and pharmacodynamics between extended-release fluvastatin and immediate-release fluvastatin in healthy Chinese subjects.

Journal: Journal of biomedicine & biotechnology 20120101

Title: Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies.

Journal: PloS one 20120101

Title: Lipid-lowering effect of fluvastatin in relation to cytochrome P450 2C9 variant alleles frequently distributed in the Czech population.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20120101

Title: A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class.

Journal: PloS one 20120101

Title: In vitro quantitative ((1))H and ((19))F nuclear magnetic resonance spectroscopy and imaging studies of fluvastatin™ in Lescol® XL tablets in a USP-IV dissolution cell.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20111220

Title: Safety and efficacy of early aggressive versus cholesterol-driven lipid-lowering strategies in heart transplantation: a pilot, randomized, intravascular ultrasound study.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20111201

Title: Pilot trial of bone-targeted therapy combining zoledronate with fluvastatin or atorvastatin for patients with metastatic renal cell carcinoma.

Journal: Clinical genitourinary cancer 20111201

Title: Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin.

Journal: Journal of Korean medical science 20111201

Title: Antiatherogenic effects of oleanolic acid in apolipoprotein E knockout mice.

Journal: European journal of pharmacology 20111130

Title: Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Title: Low-dosage statins reduce choroidal damage in hypercholesterolemic rabbits.

Journal: Acta ophthalmologica 20111101

Title: Beneficial vasoactive endothelial effects of fluvastatin: focus on prostacyclin and nitric oxide.

Journal: Heart and vessels 20111101

Title: Protective effect of dietary tocotrienols against infection and inflammation-induced hyperlipidemia: an in vivo and in silico study.

Journal: Phytotherapy research : PTR 20111101

Title: Inflammation-associated graft loss in renal transplant recipients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101

Title: Fluvastatin modulates renal water reabsorption in vivo through increased AQP2 availability at the apical plasma membrane of collecting duct cells.

Journal: Pflugers Archiv : European journal of physiology 20111101

Title: Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells.

Journal: Cancer biology & therapy 20111015

Title: Combination of fluvastatin and losartan relieves atherosclerosis and macrophage infiltration in atherosclerotic plaques in rabbits.

Journal: Acta pharmacologica Sinica 20111001

Title: Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways.

Journal: Anticancer research 20111001

Title: Fluvastatin downregulates VEGF-A expression in TNF-α-induced retinal vessel tortuosity.

Journal: Investigative ophthalmology & visual science 20110927

Title: Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders.

Journal: Pharmacological research 20110901

Title: Interactions between organic anions on multiple transporters in Caco-2 cells.

Journal: Journal of pharmaceutical sciences 20110901

Title: Effects of statin treatment on endothelial function, oxidative stress and inflammation in patients with arterial hypertension and normal cholesterol levels.

Journal: Journal of hypertension 20110901

Title: Effects of fluvastatin on insulin resistance and cardiac morphology in hypertensive patients.

Journal: Journal of human hypertension 20110801

Title: Effect of acetaminophen and fluvastatin on post-dose symptoms following infusion of zoledronic acid.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110801

Title: Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro.

Journal: Journal of thrombosis and haemostasis : JTH 20110801

Title: pH-sensitive interaction of HMG-CoA reductase inhibitors (statins) with organic anion transporting polypeptide 2B1.

Journal: Molecular pharmaceutics 20110801

Title: Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis.

Journal: Bioanalysis 20110801

Title: Theoretical study of hydrogen bond interactions of fluvastatin with ι-carrageenan and λ-carrageenan.

Journal: Journal of molecular modeling 20110701

Title: Fluvastatin does not prevent the acute-phase response to intravenous zoledronic acid in post-menopausal women.

Journal: Bone 20110701

Title: Fluvastatin reduces the high mobility group box 1 protein expression in hyperlipidemia.

Journal: International journal of cardiology 20110701

Title: [Pharmaco-economic optimization of cholesterol-lowering treatment with statins].

Journal: Medicina clinica 20110625

Title: Statins and prostate cancer diagnosis and grade in a veterans population.

Journal: Journal of the National Cancer Institute 20110608

Title: The cardioprotective effect of fluvastatin on ischemic injury via down-regulation of toll-like receptor 4.

Journal: Molecular biology reports 20110601

Title: [After bypass surgery nearly all lipids are in the normal range. However, Lp(a) is too high, what can be done?].

Journal: MMW Fortschritte der Medizin 20110526

Title: [Research on the effect of statins on insulin secretion from pancreatic islet in rats and its mechanisms].

Journal: Zhonghua nei ke za zhi 20110501

Title: [Improved virologic response in chronic hepatitis C treated with peginterferon, ribavirin and add-on drug].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110501

Title: Global effects of fluvastatin on the prothrombotic status of patients with antiphospholipid syndrome.

Journal: Annals of the rheumatic diseases 20110401

Title: Subtherapeutic, low-dose fluvastatin improves functional and morphological arterial wall properties in apparently healthy, middle-aged males--a pilot study.

Journal: Atherosclerosis 20110401

Title: Implant-induced intraperitoneal inflammatory angiogenesis is attenuated by fluvastatin.

Journal: Clinical and experimental pharmacology & physiology 20110401

Title: Long-term treatment with low-dose metoprolol CR/XL is associated with increased plaque echogenicity: the Beta-blocker Cholesterol-lowering Asymptomatic Plaque Study (BCAPS).

Journal: Atherosclerosis 20110401

Title: [Inhibitory effect of fluvastatin on lysophosphatidylcholine-induced ventricular arrhythmias in rats].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110401

Title: Involvement of Rac GTPase activation in phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to ICAM-1.

Journal: Biochemical and biophysical research communications 20110311

Title: Mechanistic clues in the cardioprotective effect of Terminalia arjuna bark extract in isoproterenol-induced chronic heart failure in rats.

Journal: Cardiovascular toxicology 20110301

Title: Effect of long term, non cholesterol lowering dose of fluvastatin treatment on oxidative stress in brain and peripheral tissues of streptozotocin-diabetic rats.

Journal: European journal of pharmacology 20110301

Title: Regulation of the endothelial plasminogen activator system by fluvastatin. Role of Rho family proteins, actin polymerisation and p38 MAP kinase.

Journal: Thrombosis and haemostasis 20110301

Title: A novel use of oxidative coupling reactions for determination of some statins (cholesterol-lowering drugs) in pharmaceutical formulations.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110301

Title: Influence of fluvastatin on cardiac function and baroreflex sensitivity in diabetic rats.

Journal: Acta pharmacologica Sinica 20110301

Title: Deteriorating effect of fluvastatin on the cholestatic liver injury induced by bile duct ligation in rats.

Journal: General physiology and biophysics 20110301

Title: Overlap syndrome of autoimmune hepatitis and primary biliary cirrhosis triggered by fluvastatin.

Journal: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20110301

Title: Inhibition of intestinal cholesterol absorption might explain cholesterol-lowering effect of telmisartan.

Journal: Journal of clinical pharmacy and therapeutics 20110201

Title: The statins fluvastatin and pravastatin exert anti-flushing effects by improving vasomotor dysfunction through nitric oxide-mediated mechanisms in ovariectomized animals.

Journal: European journal of pharmacology 20110125

Title: Comparative neuroprotective profile of statins in quinolinic acid induced neurotoxicity in rats.

Journal: Behavioural brain research 20110101

Title: Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival.

Journal: Haematologica 20110101

Title: Long-term event monitoring study of fluvastatin in Japanese patients with hypercholesterolemia: Efficacy and incidence of cardiac and other events in elderly patients (≥ 65 years old).

Journal: Journal of cardiology 20110101

Title: Statin treatment decreased serum asymmetric dimethylarginine (ADMA) levels in ischemic stroke patients.

Journal: Journal of atherosclerosis and thrombosis 20110101

Title: Comparative study between high-dose fluvastatin and low-dose fluvastatin and ezetimibe with regard to the effect on endothelial function in diabetic patients.

Journal: Endocrine journal 20110101

Title: [Chiral separation of fluvastatin enantiomers with in vitro cellular method].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110101

Title: Fluvastatin attenuates myocardial interstitial fibrosis and cardiac dysfunction in diabetic rats by inhibiting over-expression of connective tissue growth factor.

Journal: Chinese medical journal 20110101

Title: Potential benefit of statin therapy for dyslipidemia with chronic kidney disease: Fluvastatin Renal Evaluation Trial (FRET).

Journal: Internal medicine (Tokyo, Japan) 20110101

Title: Effects of multiple factorial intervention on ambulatory BP profile and renal function in hypertensive type 2 diabetic patients with overt nephropathy - a pilot study.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20110101

Title: Fluvastatin increases bone mineral density in postmenopausal women.

Journal: Fukushima journal of medical science 20110101

Title: Rhabdomyolysis secondary to hyponatraemia.

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101

Title: Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis.

Journal: PloS one 20110101

Title: Low-dose rosuvastatin improves arterial stiffness in high-risk Japanese patients with dyslipdemia in a primary prevention group.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Appreciating the medical literature: five notable articles in general internal medicine from 2009 and 2010.

Journal: Open medicine : a peer-reviewed, independent, open-access journal 20110101

Title: Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study.

Journal: Acta biochimica Polonica 20110101

Title: Differential interactions between statins and P-glycoprotein: implications for exploiting statins as anticancer agents.

Journal: International journal of cancer 20101215

Title: Fluvastatin and cisplatin demonstrate synergistic cytotoxicity in epithelial ovarian cancer cells.

Journal: Gynecologic oncology 20101201

Title: Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.

Journal: Atherosclerosis 20101201

Title: [Effects of celecoxib combined with fluvastatin on tumor growth and cell apoptosis in a xenograft model of hepatocellular carcinoma].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20101201

Title: Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway.

Journal: Indian journal of experimental biology 20101201

Title: [Fluvastatin's effect on atherogenesis in apolipoprotein-E knockout mice infected by cytomegalovirus].

Journal: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20101201

Title: The phototoxicity of fluvastatin, an HMG-CoA reductase inhibitor, is mediated by the formation of a benzocarbazole-like photoproduct.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101101

Title: Effects of add-on fluvastatin therapy in patients with chronic proteinuric nephropathy on dual renin-angiotensin system blockade: the ESPLANADE trial.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20101101

Title: Effect of sodium bicarbonate as a pharmaceutical formulation excipient on the interaction of fluvastatin with membrane phospholipids.

Journal: European biophysics journal : EBJ 20101101

Title: Effect of fluvastatin, lovastatin, nifedipine and verapamil on the systemic exposure of nateglinide in rabbits.

Journal: Biopharmaceutics & drug disposition 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Endovascular repair of abdominal aortic aneurysm.

Journal: The New England journal of medicine 20101007

Title: Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101001

Title: Effects of statins on vascular endothelial function in hypercholesterolemic patients with type 2 diabetes mellitus: fluvastatin vs. rosuvastatin.

Journal: International journal of cardiology 20100924

Title: The effect of statin therapy on arterial stiffness by measuring pulse wave velocity: a systematic review.

Journal: Current vascular pharmacology 20100901

Title: Safety of fluvastatin in patients undergoing high-risk non-cardiac surgery.

Journal: Expert opinion on drug safety 20100901

Title: A randomised determination of the Effect of Fluvastatin and Atorvastatin on top of dual antiplatelet treatment on platelet aggregation after implantation of coronary drug-eluting stents. The EFA-Trial.

Journal: Thrombosis and haemostasis 20100901

Title: Effects of HMG-CoA reductase inhibitors on continuous post-inflammatory vascular remodeling late after Kawasaki disease.

Journal: Journal of cardiology 20100901

Title: Rhabdomyolysis induced by co-administration of fluvastatin and colchicine.

Journal: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20100901

Title: Reduction of brain beta-amyloid (Abeta) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, through increase in degradation of amyloid precursor protein C-terminal fragments (APP-CTFs) and Abeta clearance.

Journal: The Journal of biological chemistry 20100716

Title: Serial coronary CT angiography-verified changes in plaque characteristics as an end point: evaluation of effect of statin intervention.

Journal: JACC. Cardiovascular imaging 20100701

Title: Sample size calculations I.

Journal: BMJ (Clinical research ed.) 20100616

Title: Applicability of non-cholesterol sterols in predicting response in cholesterol metabolism to simvastatin and fluvastatin treatment among hypercholesterolemic men.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20100601

Title: Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601

Title: The inhibitory effect of statins on urinary 11-dehydrothromboxane levels.

Journal: International angiology : a journal of the International Union of Angiology 20100601

Title: Induced expression of lectin-like oxidized ldl receptor-1 in vascular smooth muscle cells following Chlamydia pneumoniae infection and its down-regulation by fluvastatin.

Journal: Acta microbiologica et immunologica Hungarica 20100601

Title: Effects of fluvastatin therapy on serum interleukin-18 and interleukin-10 levels in patients with acute coronary syndrome.

Journal: Acta cardiologica 20100601

Title: Local application of fluvastatin improves peri-implant bone quantity and mechanical properties: a rodent study.

Journal: Acta biomaterialia 20100401

Title: Fluvastatin as an adjuvant to pegylated interferon and ribavirin in HIV/hepatitis C virus genotype 1 co-infected patients: an open-label randomized controlled study.

Journal: The Journal of antimicrobial chemotherapy 20100401

Title: The effect of a single remote injection of statin-impregnated poly (lactic-co-glycolic acid) microspheres on osteogenesis around titanium implants in rat tibia.

Journal: Biomaterials 20100401

Title: Effect of an antimicrobial agent on atherosclerotic plaques: assessment of metalloproteinase activity by molecular imaging.

Journal: Journal of the American College of Cardiology 20100323

Title: In vivo effects of fluvastatin on HCV replication in HIV-1 coinfected subjects.

Journal: Journal of viral hepatitis 20100301

Title: Does fluvastatin favour HCV replication in vivo? A pilot study on HIV-HCV co-infected patients.

Journal: Journal of viral hepatitis 20100301

Title: A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women.

Journal: Journal of lipid research 20100301

Title: Modulation of impact of high fat diet in pathological and physiological left ventricular cardiac hypertrophy by fluvastatin.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100301

Title: Differential effects of fluvastatin alone or in combination with ezetimibe on lipoprotein subfractions in patients at high risk of coronary events.

Journal: European journal of clinical investigation 20100301

Title: Fluvastatin attenuates diabetes-induced cardiac sympathetic neuropathy in association with a decrease in oxidative stress.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100301

Title: Statins and hepatitis C virus: friend or foe?

Journal: Hepatology (Baltimore, Md.) 20100101

Title: Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.

Journal: Breast cancer research and treatment 20100101

Title: Liver X receptor agonist inhibits proliferation of ovarian carcinoma cells stimulated by oxidized low density lipoprotein.

Journal: Gynecologic oncology 20100101

Title: Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles.

Journal: European journal of clinical investigation 20100101

Title: Bovine beta-lactoglobulin acts as an acid-resistant drug carrier by exploiting its diverse binding regions.

Journal: Biological chemistry 20100101

Title: Role of cellular cholesterol in pharmacologic preconditioning with cyclosporine in experimental kidney transplantation.

Journal: American journal of nephrology 20100101

Title: Oral fluvastatin reduces the severity of peritoneal adhesions in rats.

Journal: Acta chirurgica Belgica 20100101

Title: Fluvastatin increases tyrosinase synthesis induced by alpha-melanocyte-stimulating hormone in B16F10 melanoma cells.

Journal: Pharmacological reports : PR 20100101

Title: Fluvastatin in the first-line therapy of acute coronary syndrome: results of the multicenter, randomized, double-blind, placebo-controlled trial (the FACS-trial).

Journal: Trials 20100101

Title: Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Combined inhibitory effects of celecoxib and fluvastatin on the growth of human hepatocellular carcinoma xenografts in nude mice.

Journal: The Journal of international medical research 20100101

Title: Memory restorative role of statins in experimental dementia: an evidence of their cholesterol dependent and independent actions.

Journal: Pharmacological reports : PR 20100101

Title: Mechanism of statin-induced contractile dysfunction in rat cultured skeletal myofibers.

Journal: Journal of pharmacological sciences 20100101

Title: Fluvastatin and lovastatin inhibit granulocyte macrophage-colony stimulating factor-stimulated human eosinophil adhesion to inter-cellular adhesion molecule-1 under flow conditions.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201

Title: Fluvastatin in patients undergoing vascular surgery.

Journal: The New England journal of medicine 20091126

Title: Fluvastatin in patients undergoing vascular surgery.

Journal: The New England journal of medicine 20091126

Title: Novel enzyme-linked immunosorbent assay for determination of fluvastatin in plasma at picogram level.

Journal: Talanta 20091115

Title: In-vitro release kinetics and stability of anticardiovascular drugs-intercalated layered double hydroxide nanohybrids.

Journal: The journal of physical chemistry. B 20091112

Title: Roles of different CYP enzymes in the formation of specific fluvastatin metabolites by human liver microsomes.

Journal: Basic & clinical pharmacology & toxicology 20091101

Title: Drug-induced liver injury associated with statins.

Journal: Seminars in liver disease 20091101

Title: HMG-CoA reductase inhibitors (statin) prevents retinal neovascularization in a model of oxygen-induced retinopathy.

Journal: Investigative ophthalmology & visual science 20091001

Title: Statin prevents plaque disruption in apoE-knockout mouse model through pleiotropic effect on acute inflammation.

Journal: Atherosclerosis 20091001

Title: A response to the letter regarding the pleiotropic effects of fluvastatin on acute inflammatory response and the role of MMP-9 in plaque destabilization and intraplaque hemorrhage.

Journal: Atherosclerosis 20091001

Title: Validation of a fast liquid chromatography-UV method for the analysis of drugs used in combined cardiovascular therapy in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

Title: Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin.

Journal: Pharmacogenomics 20091001

Title: Evaluation of plaque stabilization by fluvastatin with carotid intima- medial elasticity measured by a transcutaneous ultrasonic-based tissue characterization system.

Journal: Journal of atherosclerosis and thrombosis 20091001

Title: Fluvastatin and perioperative events in patients undergoing vascular surgery.

Journal: The New England journal of medicine 20090903

Title: In vitro interaction between suramin and fluvastatin against clinically important Zygomycetes.

Journal: Mycoses 20090901

Title: Statins for the treatment of antiphospholipid syndrome?

Journal: Annals of the New York Academy of Sciences 20090901

Title: Pretreatment evaluation and its application on palm oil mill effluent for bio-hydrogen enhancement and methanogenic activity repression.

Journal: Pakistan journal of biological sciences : PJBS 20090815

Title: Fluvastatin prevents podocyte injury in a murine model of HIV-associated nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090801

Title: Vertical bone augmentation with fluvastatin in an injectable delivery system: a rat study.

Journal: Clinical oral implants research 20090801

Title: Fluvastatin inhibits expression of the chemokine MDC/CCL22 induced by interferon-gamma in HaCaT cells, a human keratinocyte cell line.

Journal: British journal of pharmacology 20090801

Title: No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.

Journal: British journal of clinical pharmacology 20090801

Title: [The effect of valsartan and fluvastatin on the connective tissue growth factor expression in experimental diabetic cardiomyopathy].

Journal: Zhonghua nei ke za zhi 20090801

Title: Does fluvastatin favour HCV replication in vivo? A pilot study on HIV-HCV coinfected patients.

Journal: Journal of viral hepatitis 20090701

Title: Effect of fluvastatin on progression of coronary atherosclerotic plaque evaluated by virtual histology intravascular ultrasound.

Journal: JACC. Cardiovascular interventions 20090701

Title: Can statins alter coronary plaque composition assessed by radiofrequency backscatter intravascular ultrasound?

Journal: JACC. Cardiovascular interventions 20090701

Title: Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

Title: Cholesterol biosynthesis modulation regulates dengue viral replication.

Journal: Virology 20090620

Title: In vitro activity of terbinafine associated to amphotericin B, fluvastatin, rifampicin, metronidazole and ibuprofen against Pythium insidiosum.

Journal: Veterinary microbiology 20090612

Title: Fluvastatin accelerates re-endothelialization impaired by local sirolimus treatment.

Journal: European journal of pharmacology 20090610

Title: Fluvastatin/fenofibrate vs. simvastatin/ezetimibe in patients with metabolic syndrome: different effects on LDL-profiles.

Journal: European journal of clinical investigation 20090601

Title: Bisoprolol and fluvastatin for the reduction of perioperative cardiac mortality and myocardial infarction in intermediate-risk patients undergoing noncardiovascular surgery: a randomized controlled trial (DECREASE-IV).

Journal: Annals of surgery 20090601

Title: Conversion to tacrolimus and atorvastatin in cyclosporine-treated heart transplant recipients with dyslipidemia refractory to fluvastatin.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601

Title: Fluvastatin attenuates IGF-1-induced ERK1/2 activation and cell proliferation by mevalonic acid depletion in human mesangial cells.

Journal: Life sciences 20090522

Title: Fluvastatin improves osteoporosis in fructose-fed insulin resistant model rats through blockade of the classical mevalonate pathway and antioxidant action.

Journal: International journal of molecular medicine 20090501

Title: Efficacy and safety of Monascus purpureus Went rice in children and young adults with secondary hyperlipidemia: a preliminary report.

Journal: European journal of internal medicine 20090501

Title: Statins and fenofibrate affect skeletal muscle chloride conductance in rats by differently impairing ClC-1 channel regulation and expression.

Journal: British journal of pharmacology 20090401

Title: Effect of fluvastatin on cardiac outcomes in kidney transplant patients with systemic lupus erythematosus: a randomized placebo-controlled study.

Journal: Arthritis and rheumatism 20090401

Title: Lysophosphatidylcholine increases Na+/Ca2+ exchanger expression via RhoB-geranylgeranylation in H9c2 cells.

Journal: Journal of pharmacological sciences 20090401

Title: Statins and fibrate target ClC-1 - from side effects to CLC pharmacology.

Journal: British journal of pharmacology 20090401

Title: The protective effect of fluvastatin on hydroxyl radical generation by inhibiting low-density lipoprotein (LDL) oxidation in the rat myocardium.

Journal: Microvascular research 20090301

Title: Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090301

Title: Fluvastatin attenuates severe hemorrhagic shock-induced organ damage in rats.

Journal: Resuscitation 20090301

Title: Novel biodegradable polyester poly(propylene succinate): synthesis and application in the preparation of solid dispersions and nanoparticles of a water-soluble drug.

Journal: AAPS PharmSciTech 20090301

Title: Reduced P-selectin in hearts pretreated with fluvastatin: a novel benefit for patients undergoing open heart surgery.

Journal: The Thoracic and cardiovascular surgeon 20090301

Title: [Statin therapy and muscle disorders].

Journal: Orvosi hetilap 20090208

Title: Statin use in chronic heart failure: waiting for the results of large prospective outcome trials.

Journal: International journal of cardiology 20090206

Title: Fluvastatin reduces pulmonary vein spontaneous activity through nitric oxide pathway.

Journal: Journal of cardiovascular electrophysiology 20090201

Title: Enantioselectivity in the pharmacokinetic interaction between fluvastatin and lercanidipine in healthy volunteers.

Journal: Journal of clinical pharmacology 20090201

Title: Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia?

Journal: Metabolism: clinical and experimental 20090201

Title: Statin treatment reduces glomerular inflammation and podocyte damage in rat deoxycorticosterone-acetate-salt hypertension.

Journal: Journal of hypertension 20090201

Title: [Effects of fluvastatin on the activation of p38 mitogen-activated protein kinase in glomerular mesangial cells under high concentration of glucose].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090201

Title: Cerebrovascular events in renal transplant recipients.

Journal: Transplantation 20090115

Title: Pretreatment with statin attenuates the cardiotoxicity of Doxorubicin in mice.

Journal: Cancer research 20090115

Title: Fluvastatin inhibits mast cell degranulation without changing the cytoplasmic Ca2+ level.

Journal: European journal of pharmacology 20090114

Title: Clopidogrel: review of bioanalytical methods, pharmacokinetics/pharmacodynamics, and update on recent trends in drug-drug interaction studies.

Journal: Biomedical chromatography : BMC 20090101

Title: Different galenic formulations of fluvastatin have equal lipid-lowering potential but differ in reducing lipemia-induced endothelial dysfunction.

Journal: Coronary artery disease 20090101

Title: Possible mechanisms underlying statin-induced skeletal muscle toxicity in L6 fibroblasts and in rats.

Journal: Journal of pharmacological sciences 20090101

Title: Omega 3 fatty acids induce a marked reduction of apolipoprotein B48 when added to fluvastatin in patients with type 2 diabetes and mixed hyperlipidemia: a preliminary report.

Journal: Cardiovascular diabetology 20090101

Title: The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis.

Journal: BMC cardiovascular disorders 20090101

Title: Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay.

Journal: BMC cancer 20090101

Title: [The effect of statin treatment on inflammation in patients with metabolic syndrome].

Journal: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20090101

Title: Human cardiac fibroblasts express B-type natriuretic peptide: fluvastatin ameliorates its up-regulation by interleukin-1alpha, tumour necrosis factor-alpha and transforming growth factor-beta.

Journal: Journal of cellular and molecular medicine 20090101

Title: An open pilot study exploring the efficacy of fluvastatin, pegylated interferon and ribavirin in patients with hepatitis C virus genotype 1b in high viral loads.

Journal: Intervirology 20090101

Title: Improvement in chemical and physical stability of fluvastatin drug through hydrogen bonding interactions with different polymer matrices.

Journal: Current drug delivery 20090101

Title: Geranylgeranylacetone, a non-toxic inducer of heat shock protein, induces cell death in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

Journal: Modern rheumatology 20090101

Title: Effect of HMG-CoA reductase inhibitors on activation of human gammadeltaT cells induced by Mycobacterium tuberculosis antigens.

Journal: Immunopharmacology and immunotoxicology 20090101

Title: Metabolic syndrome and cardiovascular risk in renal transplant recipients: effects of statin treatment.

Journal: Clinical transplantation 20090101

Title: Fluvastatin increases tyrosinase synthesis induced by UVB irradiation of B16F10 melanoma cells.

Journal: Folia histochemica et cytobiologica 20090101

Title: Lovastatin and fluvastatin reduce viremia and the pro-inflammatory cytokines in the patients with chronic hepatitis C.

Journal: Hepato-gastroenterology 20090101

Title: Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201

Title: Intensive lipid-lowering therapy for patients with aortic stenosis.

Journal: The American journal of cardiology 20081201

Title: Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients.

Journal: Journal of the American College of Cardiology 20081125

Title: The influence of statin medications on prostate-specific antigen levels.

Journal: Journal of the National Cancer Institute 20081105

Title: Beneficial effects of fluvastatin on liver microcirculation and regeneration after massive hepatectomy in rats.

Journal: Digestive diseases and sciences 20081101

Title: Short-term effects of fluvastatin therapy on plasma interleukin-10 levels in patients with chronic heart failure.

Journal: Coronary artery disease 20081101

Title: Fluvastatin, rhabdomyolysis, and myotoxicity.

Journal: Mayo Clinic proceedings 20081101

Title: Stimulatory effects of low-dose 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor fluvastatin on hepatocyte growth factor-induced angiogenesis: involvement of p38 mitogen-activated protein kinase.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20081101

Title: Effect of statins on fibroblasts from human nasal polyps and turbinates.

Journal: European annals of allergy and clinical immunology 20081101

Title: Toll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel.

Journal: International journal of cancer 20081015

Title: DFT study on hydroxy acid-lactone interconversion of statins: the case of atorvastatin.

Journal: Organic & biomolecular chemistry 20081007

Title: HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression.

Journal: Cardiovascular research 20081001

Title: Comparison of lycopene and fluvastatin effects on atherosclerosis induced by a high-fat diet in rabbits.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20081001

Title: Phase II study of metronomic chemotherapy with thalidomide, carboplatin-vincristine-fluvastatin in the treatment of brain stem tumors in children.

Journal: Archives of medical research 20081001

Title: Inhibitory effects of NO-fluvastatin on proliferation of human lens epithelial cells in vitro by modulating cell cycle regulatory proteins.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20081001

Title: Mitochondrial electron transport inhibition in full genomic hepatitis C virus replicon cells is restored by reducing viral replication.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20080901

Title: The human paraoxonase-1 phenotype modifies the effect of statins on paraoxonase activity and lipid parameters.

Journal: British journal of clinical pharmacology 20080901

Title: Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention.

Journal: International journal of cancer 20080901

Title: Effect of fluvastatin on serum prohepcidin levels in patients with end-stage renal disease.

Journal: Clinical biochemistry 20080901

Title: Comparative pharmacological study of free radical scavenger, nitric oxide synthase inhibitor, nitric oxide synthase activator and cyclooxygenase inhibitor against MPTP neurotoxicity in mice.

Journal: Metabolic brain disease 20080901

Title: Association between a frequent allele of the gene encoding OATP1B1 and enhanced LDL-lowering response to fluvastatin therapy.

Journal: Pharmacogenomics 20080901

Title: [Impact of statins on clopidogrel platelet inhibition in patients with acute coronary syndrome or stable angina].

Journal: Zhonghua xin xue guan bing za zhi 20080901

Title: Correlates of LDL-cholesterol goal attainment in patients under lipid lowering therapy.

Journal: Atherosclerosis 20080801

Title: Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program.

Journal: Clinical pharmacology and therapeutics 20080801

Title: Involvement of organic anion transporting polypeptides in the toxicity of hydrophilic pravastatin and lipophilic fluvastatin in rat skeletal myofibres.

Journal: British journal of pharmacology 20080801

Title: In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia.

Journal: Anti-cancer drugs 20080801

Title: Statin-induced inhibition of MCF-7 breast cancer cell proliferation is related to cell cycle arrest and apoptotic and necrotic cell death mediated by an enhanced oxidative stress.

Journal: Cancer investigation 20080801

Title: Chiral separation of fluvastatin enantiomers by capillary electrophoresis.

Journal: Archives of pharmacal research 20080801

Title: Fluvastatin in the prevention of renal transplant vasculopathy: results of a prospective, randomized, double-blind, placebo-controlled trial.

Journal: Transplantation 20080715

Title: Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expression.

Journal: Molecular pharmacology 20080701

Title: [Effects of fluvastatin on the expression of Janus kinase 2/signal transducers and activators of transcription (JAK/STAT) in glomerular mesangial cells under high concentration of glucose].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20080701

Title: Fluvastatin prevents glutamate-induced blood-brain-barrier disruption in vitro.

Journal: Life sciences 20080620

Title: Fluvastatin decreases cardiac fibrosis possibly through regulation of TGF-beta(1)/Smad 7 expression in the spontaneously hypertensive rats.

Journal: European journal of pharmacology 20080610

Title: Cholesterol synthesis inhibition elicits an integrated molecular response in human livers including decreased ACAT2.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20080601

Title: Efficacy and safety of Monascus purpureus Went rice in subjects with secondary hyperlipidemia.

Journal: Clinical and experimental nephrology 20080601

Title: Fluvastatin inhibits hepatitis C replication in humans.

Journal: The American journal of gastroenterology 20080601

Title: Topical application of statin affects bone healing around implants.

Journal: Clinical oral implants research 20080601

Title: The use of fluvastatin in cardiovascular risk management.

Journal: Expert opinion on pharmacotherapy 20080601

Title: HCV replication and statin pleotropism: an adjuvant treatment panacea?

Journal: The American journal of gastroenterology 20080601

Title: [Pleiotropic effects of statins].

Journal: Revista medica de Chile 20080601

Title: Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat.

Journal: European journal of pharmacology 20080531

Title: Effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, fluvastatin, on coronary spasm after withdrawal of calcium-channel blockers.

Journal: Journal of the American College of Cardiology 20080506

Title: Statin and stromal cell-derived factor-1 additively promote angiogenesis by enhancement of progenitor cells incorporation into new vessels.

Journal: Stem cells (Dayton, Ohio) 20080501

Title: The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15.

Journal: Pharmacogenetics and genomics 20080501

Title: Prevention of amyloid beta-induced memory impairment by fluvastatin, associated with the decrease in amyloid beta accumulation and oxidative stress in amyloid beta injection mouse model.

Journal: International journal of molecular medicine 20080501

Title: Fluvastatin improves arterial stiffness in patients with coronary artery disease and hyperlipidemia: a 5-year follow-up study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080501

Title: Short term fluvastatin treatment lowers serum asymmetric dimethylarginine levels in patients with metabolic syndrome.

Journal: International heart journal 20080501

Title: Statin induced myotoxicity: the lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080423

Title: Fluvastatin potentiates the activity of caspofungin against Aspergillus fumigatus in vitro.

Journal: Diagnostic microbiology and infectious disease 20080401

Title: Regulation of the PTEN promoter by statins and SREBP.

Journal: Human molecular genetics 20080401

Title: Fluvastatin reduces oxidative damage in human vascular endothelial cells by upregulating Bcl-2.

Journal: Journal of thrombosis and haemostasis : JTH 20080401

Title: Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study.

Journal: Pharmacogenetics and genomics 20080401

Title: Lipid levels and low-density lipoprotein cholesterol goal attainment in diabetic patients: rosuvastatin compared with other statins in usual care.

Journal: Expert opinion on pharmacotherapy 20080401

Title: [Influence of statins on the antiplatelet effect of clopidogrel and on cardiovascular outcome in patients after coronary intervention].

Journal: Deutsche medizinische Wochenschrift (1946) 20080401

Title: Fluvastatin reduces increased blood monocyte Toll-like receptor 4 expression in whole blood from patients with chronic heart failure.

Journal: International journal of cardiology 20080220

Title: Efficacy and tolerability of fluvastatin XL 80 mg alone, ezetimibe alone, and the combination of fluvastatin XL 80 mg with ezetimibe in patients with a history of muscle-related side effects with other statins.

Journal: The American journal of cardiology 20080215

Title: Determination of two HMG-CoA reductase inhibitors, pravastatin and pitavastatin, in plasma samples using liquid chromatography-tandem mass spectrometry for pharmaceutical study.

Journal: Biomedical chromatography : BMC 20080201

Title: Impact of systemic hypertension on the cardiovascular benefits of statin therapy--a meta-analysis.

Journal: The American journal of cardiology 20080201

Title: The effects of short term statin treatment on left ventricular function and inflammatory markers in patients with chronic heart failure.

Journal: International journal of cardiology 20080111

Title: [Fluvastatin induces apoptosis on human tongue carcinoma cell line HSC-3].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101

Title: Molecular modeling of two CYP2C19 SNPs and its implications for personalized drug design.

Journal: Protein and peptide letters 20080101

Title: Effects of fluvastatin extended-release (80 mg) alone and in combination with ezetimibe (10 mg) on low-density lipoprotein cholesterol and inflammatory parameters in patients with primary hypercholesterolemia: a 12-week, multicenter, randomized, open-label, parallel-group study.

Journal: Clinical therapeutics 20080101

Title: Fluvastatin treatment and withdrawal: effects on endothelial function.

Journal: Angiology 20080101

Title: Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin.

Journal: Clinical pharmacokinetics 20080101

Title: Rab-small GTPases are involved in fluvastatin and pravastatin-induced vacuolation in rat skeletal myofibers.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071201

Title: Immediate effect of fluvastatin on lipid levels in acute coronary syndrome.

Journal: Molecular and cellular biochemistry 20071201

Title: Delayed postischemic treatment with fluvastatin improved cognitive impairment after stroke in rats.

Journal: Stroke 20071201

Title: Fluvastatin inhibits activation of JAK and STAT proteins in diabetic rat glomeruli and mesangial cells under high glucose conditions.

Journal: Acta pharmacologica Sinica 20071201

Title: Transcriptional and post-transcriptional regulation of preproendothelin-1 by plaque-prone hemodynamics.

Journal: Atherosclerosis 20071001

Title: Fluvastatin inhibits hypoxic proliferation and p38 MAPK activity in pulmonary artery fibroblasts.

Journal: American journal of respiratory cell and molecular biology 20071001

Title: Mechanism of TNFalpha-induced IL-1alpha, IL-1beta and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones.

Journal: Cardiovascular research 20071001

Title: Effect of fluvastatin on vascular endothelial growth factor in rats with osteoporosis in process of fracture healing.

Journal: Chinese journal of traumatology = Zhonghua chuang shang za zhi 20071001

Title: Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion.

Journal: Journal of cardiovascular pharmacology 20071001

Title: Genetic analysis of fluvastatin response and dyslipidemia in renal transplant recipients.

Journal: Journal of lipid research 20070901

Title: Fluvastatin blunts the effect of a high-fat meal on plasma triglyceride and high-sensitivity C-reactive protein concentrations in patients at high risk for cardiovascular events.

Journal: Coronary artery disease 20070901

Title: Marked elevation of liver transaminases after high-dose fluvastatin unmasks chronic hepatitis C: safety and re-challenge.

Journal: Acta neurologica Taiwanica 20070901

Title: Low-density lipoprotein cholesterol (LDL-C) levels and LDL-C goal attainment among elderly patients treated with rosuvastatin compared with other statins in routine clinical practice.

Journal: The American journal of geriatric pharmacotherapy 20070901

Title: Risk reduction and tolerability of fluvastatin in patients with the metabolic syndrome: a pooled analysis of thirty clinical trials.

Journal: Clinical therapeutics 20070901

Title: Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070801

Title: Fluvastatin inhibits regulated secretion of endothelial cell von Willebrand factor in response to diverse secretagogues.

Journal: The Biochemical journal 20070801

Title: Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathways.

Journal: Cancer research 20070801

Title: Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials.

Journal: Journal of the American College of Cardiology 20070731

Title: The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats.

Journal: European journal of pharmacology 20070730

Title: Effect of statin withdrawal on frequency of cardiac events after vascular surgery.

Journal: The American journal of cardiology 20070715

Title: Fluvastatin enhancement of trastuzumab and classical cytotoxic agents in defined breast cancer cell lines in vitro.

Journal: Breast cancer research and treatment 20070701

Title: Fluvastatin ameliorates endotoxin induced multiple organ failure in conscious rats.

Journal: Resuscitation 20070701

Title: Simvastatin and fluvastatin reduce interleukin-6 and interleukin-8 lipopolysaccharide (LPS) stimulated production by isolated human monocytes from chronic kidney disease patients.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070701

Title: Effect of fluvastatin and valsartan, alone and in combination, on postprandial vascular inflammation and fibrinolytic activity in patients with essential hypertension.

Journal: Journal of cardiovascular pharmacology 20070701

Title: Fluvastatin alters platelet aggregability in patients with hypercholesterolemia: possible improvement of intraplatelet redox imbalance via HMG-CoA reductase.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20070601

Title: Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction.

Journal: Clinical immunology (Orlando, Fla.) 20070601

Title: Fluvastatin reverses endothelial dysfunction and increased vascular oxidative stress in rat adjuvant-induced arthritis.

Journal: Arthritis and rheumatism 20070601

Title: Time-of-intake (morning versus evening) of extended-release fluvastatin in hyperlipemic patients is without influence on the pharmacodynamics (mevalonic acid excretion) and pharmacokinetics.

Journal: International journal of clinical pharmacology and therapeutics 20070601

Title: Fluvastatin and atorvastatin affect calcium homeostasis of rat skeletal muscle fibers in vivo and in vitro by impairing the sarcoplasmic reticulum/mitochondria Ca2+-release system.

Journal: The Journal of pharmacology and experimental therapeutics 20070501

Title: HIV envelope protein gp120-triggered CD4+ T-cell adhesion to vascular endothelium is regulated via CD4 and CXCR4 receptors.

Journal: Biochimica et biophysica acta 20070501

Title: Autoimmune hepatitis after treatment with fluvastatin.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20070501

Title: Effect of paraoxonase 1 polymorphisms on the response of lipids and lipoprotein-associated enzymes to treatment with fluvastatin.

Journal: Archives of medical research 20070501

Title: Effect of clopidogrel on the steady-state pharmacokinetics of fluvastatin.

Journal: Journal of clinical pharmacology 20070501

Title: Suppressive effects of statins on acute promyelocytic leukemia cells.

Journal: Cancer research 20070501

Title: Effect of HMGCoA reductase inhibitors on cytochrome P450 expression in endothelial cell line.

Journal: Journal of cardiovascular pharmacology 20070501

Title: Efficacy and safety of extended-release fluvastatin in Turkish patients with hypercholesterolaemia: TULIPS (Turkish Lipid Study).

Journal: Current medical research and opinion 20070501

Title: The effect of fluvastatin on cardiac outcomes in patients with moderate to severe renal insufficiency: a pooled analysis of double-blind, randomized trials.

Journal: International journal of cardiology 20070412

Title: 3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design.

Journal: Biochemical and biophysical research communications 20070406

Title: Statins inhibit NK cell cytotoxicity by membrane raft depletion rather than inhibition of isoprenylation.

Journal: Atherosclerosis 20070401

Title: Tolerability of statins is not linked to CYP450 polymorphisms, but reduced CYP2D6 metabolism improves cholesteraemic response to simvastatin and fluvastatin.

Journal: Pharmacological research 20070401

Title: Inhibitors of the mevalonate pathway as potential therapeutic agents in multiple myeloma.

Journal: Leukemia research 20070301

Title: Pravastatin inhibits arrhythmias induced by coronary artery ischemia in anesthetized rats.

Journal: Journal of pharmacological sciences 20070301

Title: Fluvastatin as co-medication in heart transplant recipients with elevated creatine-kinase.

Journal: Transplantation proceedings 20070301

Title: Dose-dependent effects of docosahexaenoic acid supplementation on blood lipids in statin-treated hyperlipidaemic subjects.

Journal: Lipids 20070301

Title: Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells.

Journal: European journal of pharmacology 20070205

Title: Fluvastatin reduced liver injury in rat model of extrahepatic cholestasis.

Journal: Pediatric surgery international 20070201

Title: Lipophilic statins suppress cytotoxicity by freshly isolated natural killer cells through modulation of granule exocytosis.

Journal: International immunology 20070201

Title: [Effect of fluvastatin extended release on the protein-lipid structure of erythrocyte membrane and C-reactive protein in patients with hyperlipidemia].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070201

Title: Fluvastatin and cancer.

Journal: International journal of clinical practice 20070101

Title: Effects of statins on restenosis after coronary stent implantation.

Journal: Angiology 20070101

Title: HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells.

Journal: Journal of vascular research 20070101

Title: Involvement of the Rho/Rho kinase signaling pathway in platelet-derived growth factor BB-induced vascular endothelial growth factor expression in diabetic rat retina.

Journal: Japanese journal of ophthalmology 20070101

Title: [Influence of valsartan, fluvastatin extended release and their combination on arterial pressure, parameters of lipid metabolism, and endothelial function in patients with hypertensive disease].

Journal: Kardiologiia 20070101

Title: Novel 'plum pudding' gels as potential drug-eluting stent coatings: controlled release of fluvastatin.

Journal: Journal of biomedical materials research. Part A 20061215

Title: DFT study on hydroxy acid-lactone interconversion of statins: The case of fluvastatin.

Journal: Organic & biomolecular chemistry 20061207

Title: Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration.

Journal: Biomaterials 20061201

Title: Phosphorylation of endothelial nitric-oxide synthase is diminished in mesenteric arteries from septic rabbits depending on the altered phosphatidylinositol 3-kinase/Akt pathway: reversal effect of fluvastatin therapy.

Journal: The Journal of pharmacology and experimental therapeutics 20061201

Title: Pharmacokinetic interaction between fluvastatin and diltiazem in rats.

Journal: Biopharmaceutics & drug disposition 20061201

Title: Effects of chronic treatment with statins and fenofibrate on rat skeletal muscle: a biochemical, histological and electrophysiological study.

Journal: British journal of pharmacology 20061201

Title: Early administration of fluvastatin, but not at the onset of ischemia or reperfusion, attenuates myocardial ischemia-reperfusion injury through the nitric oxide pathway rather than its antioxidant property.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20061201

Title: The effect of fluvastatin on cICAM-1 as a biomarker of endothelial dysfunction in patients with dyslipidemia.

Journal: International angiology : a journal of the International Union of Angiology 20061201

Title: Efficacy and safety of fluvastatin in children and adolescents with heterozygous familial hypercholesterolaemia.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20061101

Title: Toxicity of statins on rat skeletal muscle mitochondria.

Journal: Cellular and molecular life sciences : CMLS 20061001

Title: SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin.

Journal: Clinical pharmacology and therapeutics 20061001

Title: Neutrophil superoxide anion generation during atorvastatin and fluvastatin therapy used in coronary heart disease primary prevention.

Journal: Journal of cardiovascular pharmacology 20061001

Title: Antioxidants suppress plasma levels of lectinlike oxidized low-density lipoprotein receptor-ligands and reduce atherosclerosis in watanabe heritable hyperlipidemic rabbits.

Journal: Journal of cardiovascular pharmacology 20061001

Title: Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer.

Journal: World journal of gastroenterology 20060921

Title: Fluvastatin stabilizes the blood-brain barrier in vitro by nitric oxide-dependent dephosphorylation of myosin light chains.

Journal: Neuropharmacology 20060901

Title: Fluvastatin treatment is not associated with an increased incidence of cancer.

Journal: International journal of clinical practice 20060901

Title: Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells.

Journal: Molecular cancer therapeutics 20060901

Title: HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1.

Journal: Life sciences 20060829

Title: Renal transplant dysfunction--importance quantified in comparison with traditional risk factors for cardiovascular disease and mortality.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801

Title: The cost-effectiveness of fluvastatin in Hungary following successful percutaneous coronary intervention.

Journal: Cardiovascular drugs and therapy 20060801

Title: Effects of statins on experimental colitis in normocholesterolemic rats.

Journal: Scandinavian journal of gastroenterology 20060801

Title: Fluvastatin alters psychomotor performance and daily activity but not the spatial memory in rats.

Journal: The Tohoku journal of experimental medicine 20060801

Title: Ezetimibe effectively decreases LDL-cholesterol in HIV-infected patients.

Journal: AIDS (London, England) 20060801

Title: Chronic fluvastatin treatment alters vascular contraction by inhibiting the Rho/Rho-kinase pathway.

Journal: Clinical and experimental pharmacology & physiology 20060801

Title: Statins, especially atorvastatin, may improve survival following brachytherapy for clinically localized prostate cancer.

Journal: Urologic nursing 20060801

Title: Healing unhealthy Hungarian hearts--at what cost?--With what benefit?

Journal: Cardiovascular drugs and therapy 20060801

Title: Inhibitory effects of statins on human monocarboxylate transporter 4.

Journal: International journal of pharmaceutics 20060706

Title: Statins are associated with a reduced infrarenal abdominal aortic aneurysm growth.

Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20060701

Title: Inhibition of transendothelial migration and invasion of human breast cancer cells by preventing geranylgeranylation of Rho.

Journal: International journal of oncology 20060701

Title: Different anti-HCV profiles of statins and their potential for combination therapy with interferon.

Journal: Hepatology (Baltimore, Md.) 20060701

Title: Management of cardiovascular risk in patients receiving calcineurin inhibitors--a case report.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Persistence and adherence to cholesterol lowering agents: evidence from Régie de l'Assurance Maladie du Québec data.

Journal: American heart journal 20060701

Title: Column-switching high-performance liquid chromatographic analysis of fluvastatin in rat plasma by direct injection.

Journal: Journal of pharmaceutical and biomedical analysis 20060616

Title: Protective effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on copper-induced hydroxyl radical generation in the rat heart.

Journal: Toxicology 20060615

Title: The effect of different doses of fluvastatin on inflammatory markers in the early phase of acute coronary syndrome.

Journal: Clinica chimica acta; international journal of clinical chemistry 20060601

Title: Effect of low-density lipoprotein cholesterol on angiotensin II sensitivity: a randomized trial with fluvastatin.

Journal: Hypertension (Dallas, Tex. : 1979) 20060601

Title: TGF-beta1-induced thrombospondin-1 expression through the p38 MAPK pathway is abolished by fluvastatin in human coronary artery smooth muscle cells.

Journal: Vascular pharmacology 20060601

Title: Use of an indirect effect model to describe the LDL cholesterol-lowering effect by statins in hypercholesterolaemic patients.

Journal: Fundamental & clinical pharmacology 20060601

Title: Effects of fluvastatin and cigarette smoking on CYP2C9 activity measured using the probe S-warfarin.

Journal: European journal of clinical pharmacology 20060601

Title: The clinical relevance of low-density-lipoproteins size modulation by statins.

Journal: Cardiovascular drugs and therapy 20060601

Title: Management of dyslipidemia in renal disease and transplantation.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20060601

Title: Effect of fluvastatin on apolipoprotein-defined lipoprotein subclasses in patients with chronic renal insufficiency.

Journal: Kidney international 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The effect of fluvastatin on plasma adiponectin levels in dyslipidaemia.

Journal: Clinical endocrinology 20060501

Title: Effect of lipid levels and lipid-lowering therapy on restenosis after coronary artery stenting.

Journal: The American journal of the medical sciences 20060501

Title: Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints.

Journal: Reviews on recent clinical trials 20060501

Title: Hydroxymethylglutaryl-coenzyme A reductase inhibitors induce apoptosis in human cardiac myocytes in vitro.

Journal: Biochemical pharmacology 20060428

Title: Fluvastatin increases heterotopically induced ossicles in mice.

Journal: Clinical and experimental pharmacology & physiology 20060401

Title: Evaluation of the pharmacokinetic interaction between fluvastatin XL and cyclosporine in renal transplant recipients.

Journal: International journal of clinical pharmacology and therapeutics 20060401

Title: Inhibitory effects of fluvastatin on cytokine and chemokine production by peripheral blood mononuclear cells in patients with allergic asthma.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060401

Title: Chiral evaluation of fluvastatin in human plasma by high-performance liquid chromatography electrospray mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060307

Title: The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia.

Journal: Atherosclerosis 20060301

Title: Fluvastatin ameliorates podocyte injury in proteinuric rats via modulation of excessive Rho signaling.

Journal: Journal of the American Society of Nephrology : JASN 20060301

Title: Hydroxymethylglutaryl-CoA reductase inhibitors in older persons with acute myocardial infarction: evidence for an age-statin interaction.

Journal: Journal of the American Geriatrics Society 20060301

Title: The insulin-like growth factor receptor 1 is a promising target for novel treatment approaches in neuroendocrine gastrointestinal tumours.

Journal: Endocrine-related cancer 20060301

Title: Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies.

Journal: Cancer science 20060201

Title: Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis.

Journal: Arthritis and rheumatism 20060201

Title: [Statins in patients with kidney failure: efficacy, tolerance, and prescription guidelines in patients with chronic kidney disease and renal transplant].

Journal: Presse medicale (Paris, France : 1983) 20060201

Title: C-reactive protein-induced upregulation of extracellular matrix metalloproteinase inducer in macrophages: inhibitory effect of fluvastatin.

Journal: Life sciences 20060125

Title: Folate co-administration improves the effectiveness of fenofibrate to decrease the lipoprotein oxidation and endothelial dysfunction surrogates.

Journal: Physiological research 20060101

Title: Statins and osteoporosis: new role for old drugs.

Journal: The Journal of pharmacy and pharmacology 20060101

Title: Inhibitory effects of amlodipine and fluvastatin on the deposition of advanced glycation end products in aortic wall of cholesterol and fructose-fed rabbits.

Journal: Biological & pharmaceutical bulletin 20060101

Title: Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101

Title: Fluvastatin does not elevate periosteal osteogenesis induce by Moloney sarcoma virus (MSV) in mice.

Journal: Pharmacological reports : PR 20060101

Title: Liquid chromatography/negative ion electrospray tandem mass spectrometry method for the quantification of fluvastatin in human plasma: validation and its application to pharmacokinetic studies.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: A disconnect between antitumor and antiangiogenic effects of fluvastatin in vitro and in vivo.

Journal: Neoplasma 20060101

Title: Zoledronic acid (Zometa) enhances the cytotoxic effect of gemcitabine and fluvastatin: in vitro isobologram studies with conventional and nonconventional cytotoxic agents.

Journal: Oncology 20060101

Title: Efficacy and safety of fluvastatin-extended release in hypercholesterolemic patients: morning administration is equivalent to evening administration.

Journal: Cardiology 20060101

Title: Cost-effectiveness analysis of cholesterol-lowering therapies in Spain.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101

Title: Influence of fluvastatin on bone formation induced by demineralized bone matrix in mice.

Journal: Pharmacological reports : PR 20060101

Title: Fluvastatin prevents oxidized low-density lipoprotein-induced injury of renal tubular epithelial cells by inhibiting the phosphatidylinositol 3-kinase/Akt-signaling pathway.

Journal: Journal of nephrology 20060101

Title: The renal safety profile of fluvastatin: results of a pooled analysis.

Journal: Renal failure 20060101

Title: No detrimental effect on renal function during long-term use of fluvastatin in renal transplant recipients in the Assessment of Lescol in Renal Transplantation (ALERT) study.

Journal: Clinical transplantation 20060101

Title: Fluvastatin and hepatic reactions: a signal from spontaneous reporting in Italy.

Journal: Drug safety 20060101

Title: Preventive effect of fluvastatin on ulcerative colitis-associated carcinogenesis in mice.

Journal: Anticancer research 20060101

Title: The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome.

Journal: The Journal of membrane biology 20060101

Title: Effects of fluvastatin on the carotid arterial media as assessed by integrated backscatter ultrasound compared with pulse-wave velocity.

Journal: Journal of the American College of Cardiology 20051206

Title: Long-term cardiac outcomes in renal transplant recipients receiving fluvastatin: the ALERT extension study.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201

Title: [Fluvastatin-induced dermatomyositis].

Journal: Annales de dermatologie et de venereologie 20051201

Title: Does time of onset of therapy alter the protective cardiovascular effect of fluvastatin after renal transplantation?

Journal: Nature clinical practice. Nephrology 20051201

Title: EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer.

Journal: Biochemical pharmacology 20051125

Title: Focal seizures after treatment with fluvastatin in a patient with a history of catastrophic antiphospholipid syndrome.

Journal: Journal of the neurological sciences 20051115

Title: The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells.

Journal: The Journal of surgical research 20051101

Title: Statin protects endothelial nitric oxide synthase activity in hypoxia-induced pulmonary hypertension.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20051101

Title: Statin-induced apoptosis linked with membrane farnesylated Ras small G protein depletion, rather than geranylated Rho protein.

Journal: The Journal of pharmacy and pharmacology 20051101

Title: Differential associations of statin and fibrate treatment with carotid arterial remodeling.

Journal: American journal of hypertension 20051101

Title: Statin toxicity: a situation that mimics viral hepatitis.

Journal: International journal of clinical pharmacology and therapeutics 20051101

Title: In-hospital initiation of statin therapy in acute coronary syndromes: maximizing the early and long-term benefits.

Journal: Chest 20051101

Title: Comparison of efficacy and safety assessment of fluvastatin in patients <65 years versus > or =65 years of age.

Journal: The American journal of cardiology 20051015

Title: Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease.

Journal: European journal of clinical pharmacology 20051001

Title: [Early intervention on atherosclerosis by fluvastatin and lectin-like oxidized low-density lipoprotein receptor-1 expression in atherosclerotic arteries in immature rabbits].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20051001

Title: The long-term course of low-density lipoprotein cholesterol after initiation of statin treatment: retrospective database analysis over 3 years in health maintenance organization enrollees.

Journal: Clinical therapeutics 20051001

Title: [Fluvastatin affects HLA class I expression on endothelial cells].

Journal: Nephrologie & therapeutique 20051001

Title: Evaluation of apoptosis and necrosis induced by statins using fluorescence-enhanced flow cytometry.

Journal: Journal of pharmaceutical and biomedical analysis 20050915

Title: Binding thermodynamics of statins to HMG-CoA reductase.

Journal: Biochemistry 20050906

Title: Combined therapy with atorvastatin and calcineurin inhibitors: no interactions with tacrolimus.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901

Title: Long-term effects of antilipidaemic therapy on left ventricular function in patients with dyslipidaemia: multigated radionuclide ventriculography study.

Journal: Nuclear medicine communications 20050901

Title: Does fluvastatin really have an antioxidant effect in humans?

Journal: Kidney international 20050901

Title: Monocyte release of tumor necrosis factor-alpha and interleukin-1beta in primary type IIa and IIb dyslipidemic patients treated with statins or fibrates.

Journal: Journal of cardiovascular pharmacology 20050901

Title: Angiotensin II-induced oxidative burst is fluvastatin sensitive in neutrophils of patients with hypercholesterolemia.

Journal: Metabolism: clinical and experimental 20050901

Title: Cardiovascular risk and renal transplantation: post hoc analyses of the Assessment of Lescol in Renal Transplantation (ALERT) Study.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20050901

Title: Fluvastatin: efficacy and safety in reducing cardiac events.

Journal: Expert opinion on pharmacotherapy 20050901

Title: Differences between statins on clinical endpoints: a population-based cohort study.

Journal: Current medical research and opinion 20050901

Title: [Influence of fluvastatin on left ventricular remodeling after myocardial infarction in rats].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20050901

Title: Regulation of connexin expression after balloon injury: possible mechanisms for antiproliferative effect of statins.

Journal: American journal of hypertension 20050901

Title: Effects of fluvastatin, an HMG-CoA reductase inhibitor, on serum levels of interleukin-18 and matrix metalloproteinase-9 in patients with hypercholesterolemia.

Journal: Clinical cardiology 20050901

Title: Decreased heart rate recovery in patients with heart failure: effect of fluvastatin therapy.

Journal: International heart journal 20050901

Title: A cost-effectiveness analysis of fluvastatin in patients with diabetes after successful percutaneous coronary intervention.

Journal: Clinical therapeutics 20050901

Title: Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells.

Journal: British journal of cancer 20050808

Title: Down-regulation of Na+/Ca2+ exchanger by fluvastatin in rat cardiomyoblast H9c2 cells: involvement of RhoB in Na+/Ca2+ exchanger mRNA stability.

Journal: Molecular pharmacology 20050801

Title: Effect of atorvastatin and fluvastatin on the metabolism of midazolam by cytochrome P450 in vitro.

Journal: Anaesthesia 20050801

Title: The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe.

Journal: Current medical research and opinion 20050801

Title: Not all statins interfere with clopidogrel during antiplatelet therapy.

Journal: European journal of clinical investigation 20050801

Title: Efficacy and safety of slow-release fluvastatin 80 mg daily in Chinese patients with hypercholesterolemia.

Journal: Journal of the Chinese Medical Association : JCMA 20050801

Title: Polymorphonuclear leukocytes may impair endothelial function: results of crossover randomized study of lipid-lowering therapies.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050601

Title: Clinical practice guidelines for managing dyslipidemias in kidney transplant patients: lessons to be learnt from the assessment of Lescol in renal transplantation (ALERT) trial.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601

Title: Clinical practice guidelines for managing dyslipidemias in kidney transplant patients.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601

Title: Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia.

Journal: Journal of vascular surgery 20050601

Title: Induction of micronuclei in CHO cells by bleomycin but not by X-irradiation is decreased by treatment with HMG-CoA reductase inhibitors.

Journal: Journal of radiation research 20050601

Title: Effect of fluvastatin on apoptosis in human CD4+ T cells.

Journal: Cellular immunology 20050601

Title: A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis.

Journal: Journal of the American College of Cardiology 20050517

Title: Renal dysfunction as a risk factor for mortality and cardiovascular disease in renal transplantation: experience from the Assessment of Lescol in Renal Transplantation trial.

Journal: Transplantation 20050515

Title: Different anticancer effects of fluvastatin on primary hepatocellular tumors and metastases in rats.

Journal: Cancer letters 20050510

Title: Beneficial effect of early initiation of lipid-lowering therapy following renal transplantation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050501

Title: Nitric oxide mediates the effect of fluvastatin on intercellular adhesion molecule-1 and platelet endothelial cell adhesion molecule-1 expression on human endothelial cells.

Journal: Annals of vascular surgery 20050501

Title: Fluvastatin plus fish oil are more effective on cardiovascular risk factors than fluvastatin alone.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050501

Title: Increase in the transcriptional activity of the endothelial nitric oxide synthase gene with fluvastatin: a relation with the -786T>C polymorphism.

Journal: Pharmacogenetics and genomics 20050501

Title: More on: fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells.

Journal: Journal of thrombosis and haemostasis : JTH 20050501

Title: A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial.

Journal: Mayo Clinic proceedings 20050501

Title: Immediate effects of fluvastain on circulating soluble endothelial protein C and free tissue factor pathway inhibitor in acute coronary syndromes.

Journal: Cardiovascular drugs and therapy 20050501

Title: Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050426

Title: Fluvastatin prevents renal injury and expression of lactin-like oxidized low-density lipoprotein receptor-1 in rabbits with hypercholesterolemia.

Journal: Chinese medical journal 20050420

Title: Renoprotective effect of combining angiotensin II receptor blockers and statins in diabetic rats.

Journal: Chinese medical journal 20050405

Title: Endothelial dysfunction and hypercontractility of vascular myocytes are ameliorated by fluvastatin in obese Zucker rats.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Cost-effectiveness of fluvastatin following successful first percutaneous coronary intervention.

Journal: The Annals of pharmacotherapy 20050401

Title: Fluvastatin ameliorates the hyperhomocysteinemia-induced endothelial dysfunction: the antioxidative properties of fluvastatin.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20050401

Title: In vitro and pharmacophore-based discovery of novel hPEPT1 inhibitors.

Journal: Pharmaceutical research 20050401

Title: Anti-oxidative effect of fluvastatin in hyperlipidemic type 2 diabetic patients.

Journal: Endocrine journal 20050401

Title: [Effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, lipid peroxidation, and aortic atherosclerosis in hypercholesterolemic rabbits].

Journal: Arquivos brasileiros de cardiologia 20050401

Title: [Effects of fluvastatin on blood levels of inflammatory cytokines in patients with unstable angina undergoing percutaneous coronary intervention].

Journal: Zhonghua xin xue guan bing za zhi 20050401

Title: Differential effect of LFA703, pravastatin, and fluvastatin on production of IL-18 and expression of ICAM-1 and CD40 in human monocytes.

Journal: Journal of leukocyte biology 20050301

Title: Fluvastatin inhibits the expression of tumor necrosis factor-alpha and activation of nuclear factor-kappaB in human endothelial cells stimulated by C-reactive protein.

Journal: Clinica chimica acta; international journal of clinical chemistry 20050301

Title: More on: Fluvastatin inhibits upregulation of tissue factor expression by antiphospholipid antibodies on endothelial cells.

Journal: Journal of thrombosis and haemostasis : JTH 20050301

Title: [The effect of early fluvastatin therapy on inflammatory factors in acute coronary syndrome].

Journal: Zhonghua nei ke za zhi 20050301

Title: Fluvastatin reduces the 4-year cardiac risk in patients with multivessel disease.

Journal: International journal of cardiology 20050227

Title: Inhibitory effect of fluvastatin on ileal ulcer formation in rats induced by nonsteroidal antiinflammatory drug.

Journal: World journal of gastroenterology 20050221

Title: [Comparative study of effects of fluvastatin and losartan on left ventricular remodeling in rat myocardial infarction].

Journal: Zhonghua yi xue za zhi 20050216

Title: Long-term fluvastatin reduces the hazardous effect of renal impairment on four-year atherosclerotic outcomes (a LIPS substudy).

Journal: The American journal of cardiology 20050215

Title: Long-term effects of statins on arterial pressure and stiffness of hypertensives.

Journal: Journal of human hypertension 20050201

Title: Fluvastatin prevents vascular hyperplasia by inhibiting phenotype modulation and proliferation through extracellular signal-regulated kinase 1 and 2 and p38 mitogen-activated protein kinase inactivation in organ-cultured artery.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050201

Title: A literature search on pharmacokinetic drug interactions of statins and analysis of how such interactions are reflected in package inserts in Japan.

Journal: Journal of clinical pharmacy and therapeutics 20050201

Title: Fluvastatin and lifestyle modification for reduction of carotid intima-media thickness and left ventricular mass progression in drug-treated hypertensives.

Journal: Atherosclerosis 20050201

Title: Fluvastatin increases the expression of adhesion molecules, monocyte chemoattractant protein-1 and tissue factor in HUVEC stimulated by patient IgG fractions containing antiphospholipid antibodies.

Journal: Thrombosis and haemostasis 20050201

Title: No effect of fluvastatin on the bone mineral density of children with minimal change glomerulonephritis and some focal mesangial cell proliferation, other than an ameliorating effect on their proteinuria.

Journal: Clinical nephrology 20050201

Title: A review of the lipid-related effects of fluvastatin.

Journal: Current medical research and opinion 20050201

Title: Revascularization of coronary atherosclerosis in patients with diabetes mellitus--there is more to it than meets the image intensifier.

Journal: American heart journal 20050201

Title: Fluvastatin reduces the impact of diabetes on long-term outcome after coronary intervention--a Lescol Intervention Prevention Study (LIPS) substudy.

Journal: American heart journal 20050201

Title: Risk factors for reaching renal endpoints in the assessment of Lescol in renal transplantation (ALERT) trial.

Journal: Transplantation 20050127

Title: Quantitative determination of fluvastatin in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry using [18O2]-fluvastatin as an internal standard.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: A comparative crossover study of the effects of fluvastatin and pravastatin (FP-COS) on circulating autoantibodies to oxidized LDL in patients with hypercholesterolemia.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: Prevalence of potentially severe drug-drug interactions in ambulatory patients with dyslipidaemia receiving HMG-CoA reductase inhibitor therapy.

Journal: Drug safety 20050101

Title: [Pilot study of the noninvasive assessment of endothelial dysfunction by post-occlusion dopplerometry velocity curves analysis in arteria brachialis].

Journal: Casopis lekaru ceskych 20050101

Title: Possible colchicine rhabdomyolysis in a fluvastatin-treated patient.

Journal: The Annals of pharmacotherapy 20050101

Title: Fluvastatin in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation.

Journal: Renal failure 20050101

Title: Sirolimus increases tissue factor expression but not activity in cultured human vascular smooth muscle cells.

Journal: BMC cardiovascular disorders 20050101

Title: Considerations in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation.

Journal: Preventive cardiology 20050101

Title: [Estimation of antioxidative effect of atorvastatin and fluvastatin used in primary prevention of coronary heart disease--effect on antioxidative enzymatic activity].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20050101

Title: Enhancement of MMP-9 activity in THP-1 cells by 7-ketocholesterol and its suppression by the HMG-CoA reductase inhibitor fluvastatin.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: [Estimation of antioxidative effect of atorvastatin and fluvastatin used in primary prevention of coronary heart disease--effect on lipid peroxidation].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20050101

Title: Effects of fluvastatin slow-release (XL 80 mg) versus simvastatin (20 mg) on the lipid triad in patients with type 2 diabetes.

Journal: Advances in therapy 20050101

Title: Effects of fluvastatin treatment on lipid profile, C-reactive protein trend, and renal function in dyslipidemic patients with chronic renal failure.

Journal: Advances in therapy 20050101

Title: Monitoring of peripheral blood cytotoxic T-cells under fluvastatin treatment in renal transplant recipients.

Journal: Journal of biological regulators and homeostatic agents 20050101

Title: Expression of serum and glucocorticoid-inducible kinase1 in diabetic rats and its modulation by fluvastatin.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

Title: 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041215

Title: Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.

Journal: Biochemistry 20041214

Title: HMG-CoA reductase inhibitor attenuates experimental autoimmune myocarditis through inhibition of T cell activation.

Journal: Cardiovascular research 20041201

Title: Relapse of respiratory insufficiency one year after organising pneumonia.

Journal: The European respiratory journal 20041201

Title: Fluvastatin reduces oxidative stress, decreases serum monocyte chemotactic protein-1 level and improves endothelial function in patients with hypercholesterolemia.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20041201

Title: Inhibitory effect of statins on the proliferation of human breast cancer cells.

Journal: International journal of clinical pharmacology and therapeutics 20041201

Title: Fluvastatin and bisoprolol for the reduction of perioperative cardiac mortality and morbidity in high-risk patients undergoing non-cardiac surgery: rationale and design of the DECREASE-IV study.

Journal: American heart journal 20041201

Title: Multiple antiplatelet effects of clopidogrel are not modulated by statin type in patients undergoing percutaneous coronary intervention.

Journal: Platelets 20041201

Title: Fluvastatin and lovastatin but not pravastatin induce neuroglial differentiation in human mesenchymal stem cells.

Journal: Journal of cellular biochemistry 20041115

Title: Fluvastatin enhances the inhibitory effects of a selective AT1 receptor blocker, valsartan, on atherosclerosis.

Journal: Hypertension (Dallas, Tex. : 1979) 20041101

Title: Effects of statins on circulating oxidized low-density lipoprotein in patients with hypercholesterolemia.

Journal: Japanese heart journal 20041101

Title: Geranylgeraniol regulates negatively caspase-1 autoprocessing: implication in the Th1 response against Mycobacterium tuberculosis.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20041015

Title: Beneficial effects of fluvastatin following percutaneous coronary intervention in patients with unstable and stable angina: results from the Lescol intervention prevention study (LIPS).

Journal: Heart (British Cardiac Society) 20041001

Title: Effect of fluvastatin on renal end points in the Assessment of Lescol in Renal Transplant (ALERT) trial.

Journal: Kidney international 20041001

Title: Immunosuppression in human peripheral blood T lymphocytes by fluvastatin.

Journal: Acta biochimica et biophysica Sinica 20041001

Title: Comparison of fluvastatin + fenofibrate combination therapy and fluvastatin monotherapy in the treatment of combined hyperlipidemia, type 2 diabetes mellitus, and coronary heart disease: a 12-month, randomized, double-blind, controlled trial.

Journal: Clinical therapeutics 20041001

Title: Is decreased libido associated with the use of HMG-CoA-reductase inhibitors?

Journal: British journal of clinical pharmacology 20040901

Title: Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells.

Journal: Journal of thrombosis and haemostasis : JTH 20040901

Title: Fluvastatin and fluvastatin extended release: a clinical and safety profile.

Journal: Expert review of cardiovascular therapy 20040901

Title: Impact of fluvastatin on hyperlipidemia after renal transplantation.

Journal: Transplantation proceedings 20040901

Title: Statin blocks Rho/Rho-kinase signalling and disrupts the actin cytoskeleton: relationship to enhancement of LPS-mediated nitric oxide synthesis in vascular smooth muscle cells.

Journal: Biochimica et biophysica acta 20040804

Title: Lipid lowering therapy with fluvastatin and pravastatin in patients with HIV infection and antiretroviral therapy: comparison of efficacy and interaction with indinavir.

Journal: Infection 20040801

Title: Statin decreases endothelial microparticle release from human coronary artery endothelial cells: implication for the Rho-kinase pathway.

Journal: Biochemical and biophysical research communications 20040716

Title: An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701

Title: Comparison of levels of matrix metalloproteinases, tissue inhibitor of metalloproteinases, interleukins, and tissue necrosis factor in carotid endarterectomy specimens from patients on versus not on statins preoperatively.

Journal: The American journal of cardiology 20040701

Title: Safety and efficacy of fluvastatin in hyperlipidemic patients with chronic renal disease.

Journal: Renal failure 20040701

Title: Statins contribute to enhancement of the number and the function of endothelial progenitor cells from peripheral blood.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20040625

Title: [Not just decreased LDL level is decisive. Which statin for patients at risk for coronary disease?].

Journal: MMW Fortschritte der Medizin 20040610

Title: [Despite coronary intervention, the risk remains high: PCI patients need additional protection].

Journal: MMW Fortschritte der Medizin 20040610

Title: [Type 2 diabetic: risk same as after infarct. With LDL not only the quantity counts].

Journal: MMW Fortschritte der Medizin 20040610

Title: fluvastatin prevents cardiac death and myocardial infarction in renal transplant recipients: post-hoc subgroup analyses of the ALERT Study.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601

Title: Fluvastatin improves endothelial dysfunction in overweight postmenopausal women through small dense low-density lipoprotein reduction.

Journal: Metabolism: clinical and experimental 20040601

Title: Effect of fluvastatin therapy on coronary flow reserve in patients with hypercholesterolemia.

Journal: The American journal of cardiology 20040601

Title: Statins augment collateral growth in response to ischemia but they do not promote cancer and atherosclerosis.

Journal: Hypertension (Dallas, Tex. : 1979) 20040601

Title: Update on statins.

Journal: Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing 20040601

Title: Effects of statins on oxidative stress.

Journal: Biological trace element research 20040501

Title: Class-specific pro-apoptotic effect of statins on human vascular endothelial cells.

Journal: Zeitschrift fur Kardiologie 20040501

Title: Cardiovascular drugs inhibit MMP-9 activity from human THP-1 macrophages.

Journal: DNA and cell biology 20040501

Title: [Statin-induced rhabdomyolysis and renal failure: also with fluvastatine].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20040501

Title: The use of statins in optimising reduction of cardiovascular risk: focus on fluvastatin.

Journal: International journal of clinical practice 20040501

Title: Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages.

Journal: Biochemical and biophysical research communications 20040409

Title: ACE inhibitors and statins acutely improve endothelial dysfunction of human coronary arterioles.

Journal: American journal of physiology. Heart and circulatory physiology 20040401

Title: Efficacy and safety of fluvastatin therapy for hypercholesterolemia after heart transplantation: results of a randomised double blind placebo controlled study.

Journal: International journal of cardiology 20040401

Title: Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.

Journal: Biochemical and biophysical research communications 20040312

Title: Steady-state pharmacokinetics of fluvastatin in healthy subjects following a new extended release fluvastatin tablet, Lescol XL.

Journal: Biopharmaceutics & drug disposition 20040301

Title: Fluvastatin slow-release lowers platelet-activating factor acetyl hydrolase activity: a placebo-controlled trial in patients with type 2 diabetes.

Journal: The Journal of clinical endocrinology and metabolism 20040301

Title: [Effects of angiotensin II receptor blockers, angiotensin converting enzyme inhibitors, 3-hydroxy-3-methyl glutaryl (HMG) CoA reductase inhibitors, amlodipine and epalrestat on cultured basilar artery smooth muscle cell proliferation].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040301

Title: Lipid-lowering effects of ethyl 2-phenacyl-3-aryl-1H-pyrrole- 4-carboxylates in rodents.

Journal: Molecules (Basel, Switzerland) 20040227

Title: Hydroxymethyl-glutaryl coenzyme a reductase inhibition limits cytomegalovirus infection in human endothelial cells.

Journal: Circulation 20040203

Title: Chronic treatment with fluvastatin improves smooth muscle dilatory function in genetically determined hyperlipoproteinemia.

Journal: Journal of cardiovascular pharmacology 20040201

Title: Fluvastatin treatment inhibits leucocyte adhesion and extravasation in models of complement-mediated acute inflammation.

Journal: Clinical and experimental immunology 20040201

Title: Fluvastatin prevents nephropathy likely through suppression of connective tissue growth factor-mediated extracellular matrix accumulation.

Journal: Experimental and molecular pathology 20040201

Title: Plasma antioxidative activity during atorvastatin and fluvastatin therapy used in coronary heart disease primary prevention.

Journal: Fundamental & clinical pharmacology 20040201

Title: Efficacy of folic acid when added to statin therapy in patients with hypercholesterolemia following acute myocardial infarction: a randomised pilot trial.

Journal: International journal of cardiology 20040201

Title: Oral anticoagulant drug interactions with statins: case report of fluvastatin and review of the literature.

Journal: Pharmacotherapy 20040201

Title: Fluvastatin inhibits raft dependent Fcgamma receptor signalling in human monocytes.

Journal: Atherosclerosis 20040201

Title: Peroxynitrite-mediated oxidative modification of low-density lipoprotein by aqueous extracts of cigarette smoke and the preventive effect of fluvastatin.

Journal: Atherosclerosis 20040201

Title: Antiproliferative effect of fluvastatin and thiazolidinedione in mesangial cells of diabetic rats.

Journal: Pediatric nephrology (Berlin, Germany) 20040101

Title: Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities.

Journal: Journal of cardiovascular pharmacology 20040101

Title: Comparisons of effects of statins (atorvastatin, fluvastatin, lovastatin, pravastatin, and simvastatin) on fasting and postprandial lipoproteins in patients with coronary heart disease versus control subjects.

Journal: The American journal of cardiology 20040101

Title: Effect of fluvastatin on long-term outcome after coronary revascularization with stent implantation.

Journal: The American journal of cardiology 20040101

Title: Relationship between hypercholesterolemia, lipid-lowering therapy and coronary flow velocity reserve evaluated by stress transesophageal echocardiography in patients with a negative coronary angiogram.

Journal: Echocardiography (Mount Kisco, N.Y.) 20040101

Title: Pharmacokinetics and lipid-lowering effect of fluvastatin in hypercholesterolaemic patients on maintenance haemodialysis.

Journal: The Journal of international medical research 20040101

Title: Fluvastatin reduces cardiac mortality in patients with coronary heart disease.

Journal: Cardiovascular drugs and therapy 20040101

Title: The influence of statins on the free intracellular calcium concentration in human umbilical vein endothelial cells.

Journal: BMC cardiovascular disorders 20040101

Title: Effects of fluvastatin in type 2 diabetic patients with hyperlipidemia: reduction in cholesterol oxidation products and VCAM-1.

Journal: Journal of atherosclerosis and thrombosis 20040101

Title: Effects of fluvastatin on endothelium-derived hyperpolarizing factor- and nitric oxide-mediated relaxations in arteries of hypertensive rats.

Journal: Clinical and experimental pharmacology & physiology 20040101

Title: Fluvastatin: clinical and safety profile.

Journal: Drugs 20040101

Title: Lichenoid drug eruption with HMG-CoA reductase inhibitors (fluvastatin and lovastatin).

Journal: Acta dermato-venereologica 20040101

Title: An economic evaluation of fluvastatin used for the prevention of cardiac events following successful first percutaneous coronary intervention in the UK.

Journal: PharmacoEconomics 20040101

Title: Fluvastatin reduces renal fibroblast proliferation and production of type III collagen: therapeutic implications for tubulointerstitial fibrosis.

Journal: Nephron. Experimental nephrology 20040101

Title: Inhibitors of differentiation/DNA binding proteins Id1 and Id3 are regulated by statins in endothelial cells.

Journal: Endothelium : journal of endothelial cell research 20040101

Title: [Effects of long acting fluvastatin on parameters of lipid metabolism in patients with type 2 diabetes and combined hyperlipidemia].

Journal: Kardiologiia 20040101

Title: Treatment with fluvastatin rapidly modulates, via different pathways, and in dependence on the baseline level, inflammation in hemodialysis patients.

Journal: Blood purification 20040101

Title: Effect of simvastatin and fluvastatin on plasma fibrinogen levels in patients with primary hypercholesterolemia.

Journal: Polish journal of pharmacology 20040101

Title: Regional intestinal absorption and biliary excretion of fluvastatin in the rat: possible involvement of mrp2.

Journal: Molecular pharmaceutics 20040101

Title: A propensity score-matched cohort study of the effect of statins, mainly fluvastatin, on the occurrence of acute myocardial infarction.

Journal: The American journal of cardiology 20031215

Title: Statins induce suppressor of cytokine signaling-3 in macrophages.

Journal: FEBS letters 20031204

Title: Edaravone, a radical scavenger, may enhance or produce antiproliferative effects of fluvastatin, amlodipine, ozagrel, GF109203X and Y27632 on cultured basilar artery smooth muscle cells.

Journal: Biological & pharmaceutical bulletin 20031201

Title: Time-dependent lipid response on fluvastatin therapy of patients with hypercholesterolemia sensitive to apoE phenotype.

Journal: Vascular pharmacology 20031201

Title: HMG-CoA reductase inhibitor, fluvastatin, has cholesterol-lowering independent 'direct' effects on atherosclerotic vessels in high cholesterol diet-fed rabbits.

Journal: Pharmacological research 20031101

Title: Inhibition of the thrombogenic and inflammatory properties of antiphospholipid antibodies by fluvastatin in an in vivo animal model.

Journal: Arthritis and rheumatism 20031101

Title: Effects of statins on adhesion molecule expression in endothelial cells.

Journal: Journal of thrombosis and haemostasis : JTH 20031101

Title: Fluvastatin improves insulin resistance in nondiabetic dyslipidemic patients.

Journal: Endocrine 20031101

Title: A multicenter, randomized, double-blind clinical trial comparing the low-density lipoprotein cholesterol-lowering ability of lovastatin 10, 20, and 40 mg/d with fluvastatin 20 and 40 mg/d.

Journal: Clinical therapeutics 20031101

Title: Inhibition of lysophosphatidic acid-induced RhoA activation and tumor cell invasion by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors.

Journal: International journal of oncology 20031001

Title: Effects of baseline level of triglycerides on changes in lipid levels from combined fluvastatin + fibrate (bezafibrate, fenofibrate, or gemfibrozil).

Journal: The American journal of cardiology 20031001

Title: Fenofibrate-induced hyperhomocysteinemia may be prevented by folate co-administration.

Journal: European journal of clinical pharmacology 20030901

Title: Protective effect of fluvastatin, an HMG-CoA reductase inhibitor, on the formation of 8-oxo-2'-deoxyguanosine in the nuclear DNA of hamster pancreas after a single administration of N-nitrosobis(2-oxopropyl)amine.

Journal: Biological & pharmaceutical bulletin 20030901

Title: A retrospective analysis of the effect of noncompliance on time to first major adverse cardiac event in LIPS.

Journal: Clinical therapeutics 20030901

Title: [The expression of connective tissue growth factor in renal cortex of 5/6 nephrectomized rats and its modulation by fluvastatin].

Journal: Zhonghua yi xue za zhi 20030825

Title: Fluvastatin reduces atherogenic lipids without any effect on native endothelial function early after kidney transplantation.

Journal: Clinical transplantation 20030801

Title: Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers.

Journal: Clinical pharmacology and therapeutics 20030801

Title: Effect of fluvastatin and dipyridamole on proteinuria and renal function in childhood IgA nephropathy with mild histological findings and moderate proteinuria.

Journal: Clinical nephrology 20030801

Title: Fluvastatin attenuates nitrate tolerance in patients with ischemic heart disease complicating hypercholesterolemia.

Journal: International journal of cardiology 20030801

Title: Reduction of myocardial infarct size by fluvastatin.

Journal: American journal of physiology. Heart and circulatory physiology 20030701

Title: Preservation of endothelial function by the HMG-CoA reductase inhibitor fluvastatin through its lipid-lowering independent antioxidant properties in atherosclerotic rabbits.

Journal: Pharmacology 20030701

Title: Preservation of endothelium-dependent and Nomega-nitro-L-arginine methyl ester- and indomethacin-resistant arterial relaxation in high-cholesterol-diet fed rabbits by treatment with fluvastatin, an HMG-CoA reductase inhibitor.

Journal: Journal of cardiovascular pharmacology 20030701

Title: Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells.

Journal: Prostaglandins & other lipid mediators 20030701

Title: Effect of fluvastatin on cardiac outcomes in renal transplant recipients: a multicentre, randomised, placebo-controlled trial.

Journal: Lancet (London, England) 20030614

Title: Cost effectiveness of statin therapy for the primary prevention of major coronary events in individuals with type 2 diabetes.

Journal: Diabetes care 20030601

Title: Reduction of arteriosclerotic nanoplaque formation and size by fluvastatin in a receptor-based biosensor model.

Journal: Cardiovascular research 20030601

Title: Antioxidative potential of fluvastatin via the inhibition of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity.

Journal: Biological & pharmaceutical bulletin 20030601

Title: Beneficial effects of fluvastatin on progressive renal allograft dysfunction.

Journal: Transplantation proceedings 20030601

Title: The Lescol Intervention Prevention Study (LIPS): start all patients on statins early after PCI.

Journal: Cleveland Clinic journal of medicine 20030601

Title: Serum lipid comparison in patients treated by statins or fibrates: existence of bad HDL-C responders to statins.

Journal: Acta cardiologica 20030601

Title: The effect of an HMG-CoA reductase inhibitor on arteriosclerotic nanoplaque formation and size in a biosensor model.

Journal: Biosensors & bioelectronics 20030501

Title: Effect of a 3-year therapy with the 3-hydroxy-3-methylglutaryl coenzyme a reductase-inhibitor fluvastatin on endothelial function and distensibility of large arteries in hypercholesterolemic renal transplant recipient.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20030501

Title: Effect of dietary intervention and lipid-lowering treatment on brachial vasoreactivity in patients with ischemic heart disease and hypercholesterolemia.

Journal: American heart journal 20030501

Title: [Treatment of hypercholesterolemia in kidney transplant recipients].

Journal: Deutsche medizinische Wochenschrift (1946) 20030417

Title: [Better prognosis for dialysis dependent type 2 diabetic patient. Statin delays arterial onset of arterial stiffness].

Journal: MMW Fortschritte der Medizin 20030417

Title: Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins.

Journal: Molecular pharmacology 20030401

Title: Vascular smooth muscle cell activation by C-reactive protein.

Journal: Cardiovascular research 20030401

Title: Randomized, double-blind, placebo-controlled comparison of the action of orlistat, fluvastatin, or both an anthropometric measurements, blood pressure, and lipid profile in obese patients with hypercholesterolemia prescribed a standardized diet.

Journal: Clinical therapeutics 20030401

Title: [Effect of fluvastatin and fenofibrate on reactive oxygen species generation and lipid peroxidation in patients with dyslipidemia].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030401

Title: [Effect of fluvastatin and fenofibrate on the antioxidative barrier enzyme activity in patients with dyslipidemia].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030401

Title: The sorry saga of the statins in New Zealand--pharmacopolitics versus patient care.

Journal: The New Zealand medical journal 20030314

Title: Response from PHARMAC: difficult choices.

Journal: The New Zealand medical journal 20030314

Title: Treating dyslipidemia with statins: the risk-benefit profile.

Journal: American heart journal 20030301

Title: Statins inhibit high glucose-mediated neutrophil-endothelial cell adhesion through decreasing surface expression of endothelial adhesion molecules by stimulating production of endothelial nitric oxide.

Journal: Microvascular research 20030301

Title: Comparison of treatment with fluvastatin extended-release 80-mg tablets and immediate-release 40-mg capsules in patients with primary hypercholesterolemia.

Journal: Clinical therapeutics 20030301

Title: Cytochrome P450 epoxygenases and vascular tone: novel role for HMG-CoA reductase inhibitors in the regulation of CYP 2C expression.

Journal: Biochimica et biophysica acta 20030217

Title: Fluvastatin induces apoptosis of vascular endothelial cells: blockade by glucocorticoids.

Journal: Cardiovascular surgery (London, England) 20030201

Title: Sensitive assay for the determination of fluvastatin in plasma utilizing high-performance liquid chromatography with fluorescence detection.

Journal: Therapeutic drug monitoring 20030201

Title: Fluvastatin prevents renal dysfunction and vascular NO deficit in apolipoprotein E-deficient mice.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20030201

Title: Panax notoginseng (Burk.) effects on fibrinogen and lipid plasma level in rats fed on a high-fat diet.

Journal: Phytotherapy research : PTR 20030201

Title: Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation.

Journal: Arquivos brasileiros de cardiologia 20030201

Title: Frequency of creatine kinase elevation during treatment with fluvastatin in combination with fibrates (bezafibrate, fenofibrate, or gemfibrozil).

Journal: The American journal of cardiology 20030115

Title: Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation.

Journal: Circulation 20030107

Title: Fluvastin therapy affects TAFI concentration in kidney transplant recipients.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20030101

Title: A model to assess the cost effectiveness of statins in achieving the UK National Service Framework target cholesterol levels.

Journal: PharmacoEconomics 20030101

Title: An economic analysis of the Atorvastatin Comparative Cholesterol Efficacy and Safety Study (ACCESS).

Journal: PharmacoEconomics 20030101

Title: Variable influence of statins on isoprostanes in hyperlipidemia.

Journal: Advances in experimental medicine and biology 20030101

Title: Short-term efficacy and safety of extended-release fluvastatin in a large cohort of elderly patients.

Journal: The American journal of geriatric cardiology 20030101

Title: [Combination therapy with fluvastatin and fenofibrate in ischemic heart disease patients with combined hyperlipidemia and type 2 diabetes].

Journal: Kardiologiia 20030101

Title: [High therapeutic effect and safety of fluvastatin].

Journal: Pharmazie in unserer Zeit 20030101

Title: HMG CoA reductase inhibitor fluvastatin arrests the development of implanted hepatocarcinoma in rats.

Journal: Anticancer research 20030101

Title: Effects of D-003, a mixture of long-chain aliphatic primary acids, fluvastatin and the combined therapy of D-003 plus fluvastatin on the lipid profile of normocholesterolemic rabbits.

Journal: International journal of tissue reactions 20030101

Title: Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials.

Journal: BMC family practice 20030101

Title: Fluvastatin increases LDL particle size and reduces oxidative stress in patients with hyperlipidemia.

Journal: Journal of atherosclerosis and thrombosis 20030101

Title: Fluvastatin induces apoptosis in rat neonatal cardiac myocytes: a possible mechanism of statin-attenuated cardiac hypertrophy.

Journal: Journal of cardiovascular pharmacology 20021201

Title: Fluvastatin-induced rhabdomyolysis.

Journal: The Annals of pharmacotherapy 20021201

Title: Effect of fluvastatin slow-release on low density lipoprotein (LDL) subfractions in patients with type 2 diabetes mellitus: baseline LDL profile determines specific mode of action.

Journal: The Journal of clinical endocrinology and metabolism 20021201

Title: Effect of fluvastatin on ischaemia following acute myocardial infarction: a randomized trial.

Journal: European heart journal 20021201

Title: [Effects of fluvastatin on the levels of C-reactive protein and lipids in patients with hyperlipidemia].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021201

Title: Time-dependent effect of statins on platelet function in hypercholesterolaemia.

Journal: European journal of clinical investigation 20021201

Title: Rapid spectrophotometric method for quantitative determination of simvastatin and fluvastatin in human serum and pharmaceutical formulations.

Journal: Die Pharmazie 20021201

Title: Toward a role for statins in immunomodulation.

Journal: Molecular interventions 20021201

Title: Regulation of interleukin-8 expression by HMG-CoA reductase inhibitors in human vascular smooth muscle cells.

Journal: Atherosclerosis 20021101

Title: Effects of SREBF-1a and SCAP polymorphisms on plasma levels of lipids, severity, progression and regression of coronary atherosclerosis and response to therapy with fluvastatin.

Journal: Journal of molecular medicine (Berlin, Germany) 20021101

Title: Fluvastatin.

Journal: Expert opinion on pharmacotherapy 20021101

Title: Stereospecific disposition of fluvastatin in streptozotocin-induced diabetic rats.

Journal: Canadian journal of physiology and pharmacology 20021101

Title: Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients.

Journal: Atherosclerosis 20021001

Title: Fluvastatin remodels resistance arteries in genetically hypertensive rats, even in the absence of any effect on blood pressure.

Journal: Clinical and experimental pharmacology & physiology 20021001

Title: Hypercholesterolaemia and treatment with statins do not alter L-arginine-induced changes of renal haemodynamics.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021001

Title: Biosensing of arteriosclerotic nanoplaque formation and interaction with an HMG-CoA reductase inhibitor.

Journal: Acta physiologica Scandinavica 20021001

Title: Severe rhabdomyolysis after laparoscopic surgery for adenocarcinoma of the rectum in two patients treated with statins.

Journal: Anesthesiology 20021001

Title: Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

Title: Efficacy and safety of fluvastatin in hyperlipidemic protease inhibitor-treated HIV-infected patients.

Journal: AIDS (London, England) 20020927

Title: Inhibitory effect of fluvastatin on lysophosphatidylcholine-induced nonselective cation current in Guinea pig ventricular myocytes.

Journal: Molecular pharmacology 20020901

Title: [Antilipemic agents in combined therapy].

Journal: Orvosi hetilap 20020825

Title: Inhibition of proliferation and signalling mechanisms in human lymphocytes by fluvastatin.

Journal: Clinical and experimental pharmacology & physiology 20020801

Title: Impact of treatment of dyslipidemia on renal function, fat deposits and scarring in patients with persistent nephrotic syndrome.

Journal: Nephron 20020801

Title: Fluvastatin prevents development of arterial stiffness in haemodialysis patients with type 2 diabetes mellitus.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020801

Title: The HMG Co-A reductase inhibitors ('statins') and myotoxic effects.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020801

Title: Valsartan therapy has additive anti-oxidative effect to that of fluvastatin therapy against low-density lipoprotein oxidation: studies in hypercholesterolemic and hypertensive patients.

Journal: Journal of cardiovascular pharmacology 20020701

Title: Statin-induced apoptosis of vascular endothelial cells is blocked by dexamethasone.

Journal: The Journal of endocrinology 20020701

Title: Cyclosporin A pharmacokinetics in a patient with psoriasis and obesity, presenting with high levels of low-density [correction for destiny] lipoprotein.

Journal: European journal of clinical pharmacology 20020701

Title: [Clinical study of the month. The LIPS study: fluvastatin for prevention of cardiac events following percutaneous coronary angioplasty].

Journal: Revue medicale de Liege 20020701

Title: Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial.

Journal: JAMA 20020626

Title: Preventing cardiac events and restenosis after percutaneous coronary intervention.

Journal: JAMA 20020626

Title: Statin enhances cytokine-mediated induction of nitric oxide synthesis in vascular smooth muscle cells.

Journal: Cardiovascular research 20020601

Title: Statins and risk of polyneuropathy: a case-control study.

Journal: Neurology 20020514

Title: [Effects of fluvastatin on plasma lipid abnormalities in hemodialysis patients with chronic renal failure].

Journal: Nihon Jinzo Gakkai shi 20020501

Title: Antioxidative effects of fluvastatin on superoxide anion activated by angiotensin II in human aortic smooth muscle cells.

Journal: Cardiovascular drugs and therapy 20020501

Title: [Taking statins immediately after heart catheterization. Rate of complications is cut in half in diabetic patients].

Journal: MMW Fortschritte der Medizin 20020404

Title: Effects of hypocholesterolaemic agents on the expression and activity of 3-hydroxy-3-methylglutaryl-CoA reductase in the fat body of the German cockroach.

Journal: Archives of insect biochemistry and physiology 20020401

Title: Fluvastatin reduces tissue factor expression and macrophage accumulation in carotid lesions of cholesterol-fed rabbits in the absence of lipid lowering.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020401

Title: Cholesterol-induced thrombogenicity of the vessel wall: inhibitory effect of fluvastatin.

Journal: Thrombosis and haemostasis 20020401

Title: Managing dyslipidemia in the high-risk patient.

Journal: The American journal of cardiology 20020307

Title: Pharmacokinetics of fluvastatin in subjects with renal impairment and nephrotic syndrome.

Journal: Journal of clinical pharmacology 20020301

Title: [Complete remission of minimal change nephrotic syndrome with type 2 diabetes mellitus treated by microemulsion formulation of cyclosporin and fluvastatin].

Journal: Nihon Jinzo Gakkai shi 20020301

Title: [Stimulation of bone formation by anti-hyperlipidemic agent statins and its mechanism of action].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020301

Title: HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells.

Journal: Cardiovascular drugs and therapy 20020301

Title: Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction.

Journal: Circulation 20020219

Title: Fluvastatin enhances apoptosis in cytokine-stimulated vascular smooth muscle cells.

Journal: Journal of cardiovascular pharmacology 20020201

Title: 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis.

Journal: Gastroenterology 20020201

Title: Fluvastatin reduces modification of low-density lipoprotein in hyperlipidemic rabbit loaded with oxidative stress.

Journal: European journal of pharmacology 20020201

Title: Safety and efficacy of atorvastatin in heart transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020201

Title: Lipid-lowering therapy with fluvastatin inhibits oxidative modification of low density lipoprotein and improves vascular endothelial function in hypercholesterolemic patients.

Journal: Atherosclerosis 20020201

Title: Effect of fluvastatin and pravastatin, HMG-CoA reductase inhibitors, on fluconazole activity against Candida albicans.

Journal: Journal of medical microbiology 20020201

Title: Electrochemical study of fluvastatin sodium--analytical application to pharmaceutical dosage forms, human serum, and simulated gastric juice.

Journal: Analytical and bioanalytical chemistry 20020201

Title: Kinetic properties and inhibition of Trypanosoma cruzi 3-hydroxy-3-methylglutaryl CoA reductase.

Journal: FEBS letters 20020116

Title: Frequency of creatine kinase elevation during treatment with fluvastatin.

Journal: The American journal of cardiology 20020115

Title: Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.

Journal: Biochemical and biophysical research communications 20020111

Title: Fluvastatin improves lipid abnormalities in patients with moderate to advanced chronic renal insufficiency.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101

Title: Effects of fluvastatin treatment on insulin sensitivity in patients with hyperlipidaemia.

Journal: The Journal of international medical research 20020101

Title: The effect of fluvastatin on plasma fibrinogen levels.

Journal: Current medical research and opinion 20020101

Title: Effects of fluvastatin on homocysteine and serum lipids in kidney allograft recipients.

Journal: Annals of transplantation 20020101

Title: [Effect of fluvastain and its combination with aspirin and trental on hemostasis and microcirculation in atherosclerosis].

Journal: Terapevticheskii arkhiv 20020101

Title: Acute pancreatitis induced by fluvastatin therapy.

Journal: Journal of clinical gastroenterology 20020101

Title: Plasma lipids and blood fluidity in patients with polygenic hypercholesterolaemia treated with fluvastatin.

Journal: Clinical hemorheology and microcirculation 20020101

Title: Neuromuscular toxicity in nephrotic patients treated with fluvastatin.

Journal: Journal of nephrology 20020101

Title: Stereoselective analysis of fluvastatin in human plasma for pharmacokinetic studies.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20011205

Title: Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20011201

Title: Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: effect on the proadhesive and proinflammatory phenotype.

Journal: Arthritis and rheumatism 20011201

Title: Stability of atheromatous plaque affected by lesional composition: study of WHHL rabbits treated with statins.

Journal: Annals of the New York Academy of Sciences 20011201

Title: Antioxidative effects of fluvastatin and its metabolites against oxidative DNA damage in mammalian cultured cells.

Journal: Free radical research 20011201

Title: Fluvastatin depresses the enhanced lipid peroxidation in vitamin E-deficient hamsters.

Journal: Free radical research 20011201

Title: Effect of diet and treatment with statins on platelet-dependent thrombin generation in hypercholesterolemic subjects.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20011201

Title: Effect of fluvastatin on acute renal allograft rejection: a randomized multicenter trial.

Journal: Kidney international 20011101

Title: Lovastatin increases nitric oxide synthesis in IL-1 beta-stimulated smooth muscle cells.

Journal: Chinese medical journal 20011101

Title: The use over time of statins in coronary patients in an Italian tertiary referral center.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20011101

Title: Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis.

Journal: Circulation 20011030

Title: Validated analysis of fluvastatin in a pharmaceutical capsule formulation and serum by capillary electrophoresis.

Journal: Biomedical chromatography : BMC 20011001

Title: The influence of plasma lipoprotein (a) on angiographic restenosis and coronary events in patients undergoing planned coronary balloon angioplasty. Ancillary analysis of the Fluvastatin Angioplasty Restenosis (FLARE) trial.

Journal: Atherosclerosis 20011001

Title: Managed care trends in statin usage.

Journal: Managed care (Langhorne, Pa.) 20011001

Title: Pharmacokinetics and pharmacodynamics of fluvastatin in heart transplant recipients taking cyclosporine A.

Journal: Journal of cardiovascular pharmacology and therapeutics 20011001

Title: Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts.

Journal: Transplantation 20010927

Title: Lipid-independent effects of an estrogen-statin combination: inhibition of expression of adhesion molecules and plasminogen activator inhibitor--I in human endothelial cell cultures.

Journal: Climacteric : the journal of the International Menopause Society 20010901

Title: Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner.

Journal: Methods and findings in experimental and clinical pharmacology 20010901

Title: Determination of fluvastatin and its five metabolites in human plasma using simple gradient reversed-phase high-performance liquid chromatography with ultraviolet detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010825

Title: Achieving and maintaining National Cholesterol Education Program low-density lipoprotein cholesterol goals with five statins.

Journal: The American journal of medicine 20010815

Title: Inhibitory effects of fluvastain and its metabolites on the formation of several reactive oxygen species.

Journal: Life sciences 20010810

Title: Fluvastatin inhibits O2- and ICAM-1 levels in a rat model with aortic remodeling induced by pressure overload.

Journal: American journal of physiology. Heart and circulatory physiology 20010801

Title: Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins).

Journal: European journal of clinical pharmacology 20010801

Title: Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins.

Journal: Atherosclerosis 20010701

Title: Lipophilic statins augment inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes.

Journal: Journal of cardiovascular pharmacology 20010701

Title: Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010701

Title: Effects of fluvastatin and its major metabolites on low-density lipoprotein oxidation and cholesterol esterification in macrophages.

Journal: Japanese journal of pharmacology 20010701

Title: Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors.

Journal: Cancer research 20010615

Title: Fluvastatin suppresses oxidative stress and fibrosis in the interstitium of mouse kidneys with unilateral ureteral obstruction.

Journal: Kidney international 20010601

Title: HMG-CoA reductase inhibitors prevent migration of human coronary smooth muscle cells through suppression of increase in oxidative stress.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20010601

Title: LDL-receptor gene mutations and the hypocholesterolemic response to statin therapy.

Journal: Clinical genetics 20010601

Title: Plasma vascular endothelial growth factor and its receptor Flt-1 in patients with hyperlipidemia and atherosclerosis and the effects of fluvastatin or fenofibrate.

Journal: The American journal of cardiology 20010515

Title: Novel polymorphisms in promoter region of atp binding cassette transporter gene and plasma lipids, severity, progression, and regression of coronary atherosclerosis and response to therapy.

Journal: Circulation research 20010511

Title: Safety, tolerability, and pharmacokinetics of an extended-release formulation of fluvastatin administered once daily to patients with primary hypercholesterolemia.

Journal: Journal of cardiovascular pharmacology 20010501

Title: Effects of 1-year treatment with fluvastatin or pravastatin on bone.

Journal: The American journal of medicine 20010501

Title: Efficacy and safety of treatment with low-dose fluvastatin in hypercholesterolemic renal transplant recipients.

Journal: Transplantation proceedings 20010501

Title: Statin induced myopathy does not show up in MIBI scintigraphy.

Journal: Nuclear medicine communications 20010501

Title: A cost-effectiveness model of alternative statins to achieve target LDL-cholesterol levels.

Journal: International journal of clinical practice 20010501

Title: Effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on nitric oxide-induced hydroxyl radical generation in the rat heart.

Journal: Biochimica et biophysica acta 20010430

Title: Fluvastatin lowers atherogenic dense low-density lipoproteins in postmenopausal women with the atherogenic lipoprotein phenotype.

Journal: Circulation 20010417

Title: Low-dose metoprolol CR/XL and fluvastatin slow progression of carotid intima-media thickness: Main results from the Beta-Blocker Cholesterol-Lowering Asymptomatic Plaque Study (BCAPS).

Journal: Circulation 20010403

Title: A HMG-CoA reductase inhibitor possesses a potent anti-atherosclerotic effect other than serum lipid lowering effects--the relevance of endothelial nitric oxide synthase and superoxide anion scavenging action.

Journal: Atherosclerosis 20010401

Title: Fluvastatin therapy improves microcirculation in patients with hyperlipidaemia.

Journal: Atherosclerosis 20010401

Title: Comparative study of HMG-CoA reductase inhibitors on fibrinogen.

Journal: Atherosclerosis 20010401

Title: Effect of fluvastatin on endothelium-dependent brachial artery vasodilation in patients after renal transplantation.

Journal: Kidney international 20010401

Title: Effects of fluvastatin on cardiac events in renal transplant patients: ALERT (Assessment of Lescol in Renal Transplantation) study design and baseline data.

Journal: Journal of cardiovascular risk 20010401

Title: Dose dependency of fluvastatin pharmacokinetics in serum determined by reversed phase HPLC.

Journal: Journal of cardiovascular pharmacology and therapeutics 20010401

Title: Cholesterol biosynthesis regulation and protein changes in rat liver following treatment with fluvastatin.

Journal: Toxicology letters 20010331

Title: Immunological response to oxidized LDL occurs in association with oxidative DNA damage independently of serum LDL concentrations in dyslipidemic patients.

Journal: Clinica chimica acta; international journal of clinical chemistry 20010301

Title: Statin therapy--what now?

Journal: Drug and therapeutics bulletin 20010301

Title: Effects of fluvastatin on biliary lipids in subjects with an elevated cholesterol saturation index.

Journal: European journal of clinical pharmacology 20010301

Title: A comparison of the efficacy and tolerability of titrate-to-goal regimens of simvastatin and fluvastatin: a randomized, double-blind study in adult patients at moderate to high risk for cardiovascular disease.

Journal: Clinical therapeutics 20010301

Title: [Fluvastatin].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [Antioxidants].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: A clinical focus on statins.

Journal: Current opinion in investigational drugs (London, England : 2000) 20010301

Title: Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits.

Journal: Circulation 20010220

Title: A prospective study of paraoxonase gene Q/R192 polymorphism and severity, progression and regression of coronary atherosclerosis, plasma lipid levels, clinical events and response to fluvastatin.

Journal: Atherosclerosis 20010215

Title: Protective effect of fluvastatin on degradation of apolipoprotein B by a radical reaction in human plasma.

Journal: Biological & pharmaceutical bulletin 20010201

Title: Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes.

Journal: The Journal of pharmacy and pharmacology 20010201

Title: Regulation of endothelial nitric oxide synthase and endothelin-1 expression by fluvastatin in human vascular endothelial cells.

Journal: Japanese journal of pharmacology 20010201

Title: Efficacy and tolerability of fluvastatin extended-release delivery system: a pooled analysis.

Journal: Clinical therapeutics 20010201

Title: [The role of HDL in the prevention of cardiovascular events].

Journal: Orvosi hetilap 20010121

Title: Effective use of statins to prevent coronary heart disease.

Journal: American family physician 20010115

Title: Statin trials in progress: unanswered questions.

Journal: Current atherosclerosis reports 20010101

Title: New statins and new doses of older statins.

Journal: Current atherosclerosis reports 20010101

Title: Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits.

Journal: Atherosclerosis 20010101

Title: [Antioxidative effects of fluvastatin, and its major metabolites [II]].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010101

Title: Effects of fluvastatin and bezafibrate combination on plasma fibrinogen, t-plasminogen activator inhibitor and C reactive protein levels in coronary artery disease patients with mixed hyperlipidaemia (FACT Study)--a rebuttal.

Journal: Thrombosis and haemostasis 20010101

Title: Comparison of the efficacy and tolerability of fluvastatin extended-release and immediate-release formulations in the treatment of primary hypercholesterolemia: a randomized trial.

Journal: Clinical therapeutics 20010101

Title: Protective effects of fluvastatin against reactive oxygen species induced DNA damage and mutagenesis.

Journal: Free radical research 20010101

Title: Effect of an estrogen/statin combination on biochemical markers of endothelial function in human coronary artery cell cultures.

Journal: Menopause (New York, N.Y.) 20010101

Title: Clinical pharmacokinetics of fluvastatin.

Journal: Clinical pharmacokinetics 20010101

Title: Further evidence for direct vascular actions of statins: effect on endothelial nitric oxide synthase and adhesion molecules.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101

Title: The effect of fluvastatin on parameters of bone remodeling.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101

Title: Newer HMG-CoA reductase inhibitor (statin) therapies.

Journal: Clinical cardiology 20010101

Title: Synthetic statins: more data on newer lipid-lowering agents.

Journal: Current medical research and opinion 20010101

Title: The effect of fluvastatin of hyperlipidemia in renal transplant recipients: a prospective, placebo-controlled study.

Journal: International urology and nephrology 20010101

Title: Effects of fluvastatin and bezafibrate combination on plasma fibrinogen, t-plasminogen activator inhibitor and C reactive protein levels in coronary artery disease patients with mixed hyperlipidaemia (FACT study). Fluvastatin Alone and in Combination Treatment.

Journal: Thrombosis and haemostasis 20000401

Title: Statin + fibrate combination therapy fluvastatin with bezafibrate or ciprofibrate in high risk patients with vascular disease.

Journal: International journal of cardiology 19990601

Title: The effects of fluvastatin, a CYP2C9 inhibitor, on losartan pharmacokinetics in healthy volunteers.

Journal: Journal of clinical pharmacology 19990401

Title: Two different types of exercise-induced muscle pain without myopathy and CK-elevation during HMG-Co-enzyme-A-reductase inhibitor treatment.

Journal: Atherosclerosis 19990401

Title: In vitro activity of fluvastatin, a cholesterol-lowering agent, and synergy with flucanazole and itraconazole against Candida species and Cryptococcus neoformans.

Journal: Antimicrobial agents and chemotherapy 19970401

Title: Effect of fluvastatin or bezafibrate on the distribution of high density lipoprotein subpopulations in patients with familial hypercholesterolemia.

Journal: Arzneimittel-Forschung 19960901

Title: Fluvastatin in combination with other lipid-lowering agents.

Journal: British journal of clinical practice. Supplement 19960101

Title: Efficacy and safety of triple therapy (fluvastatin-bezafibrate-cholestyramine) for severe familial hypercholesterolemia.

Journal: The American journal of cardiology 19950713

Title: Treatment of primary hypercholesterolemia: fluvastatin versus bezafibrate.

Journal: The American journal of medicine 19940606

Title: Efficacy and safety of a combination fluvastatin-bezafibrate treatment for familial hypercholesterolemia: comparative analysis with a fluvastatin-cholestyramine combination.

Journal: The American journal of medicine 19940501

Title: HMG-CoA reductase inhibitors: design, synthesis, and biological activity of tetrahydroindazole-substituted 3,5-dihydroxy-6-heptenoic acid sodium salts.

Journal: Journal of medicinal chemistry 19931112

Title: Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids.

Journal: Journal of medicinal chemistry 19911001

Title: Relationship between tissue selectivity and lipophilicity for inhibitors of HMG-CoA reductase.

Journal: Journal of medicinal chemistry 19910101

Title: Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24. [Epub ahead of print

Title: Makabe S, Takahashi Y, Watanabe H, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.

Title: Zhang W, Wu J, Zhou L, et al. Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway. Indian J Exp Biol. 2010 Dec;48(12):1167-74.

Title: Scripture CD, Pieper JA. Clinical pharmacokinetics of fluvastatin. Clin Pharmacokinet. 2001;40(4):263-81.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:93957-55-2 Molecular Formula|93957-55-2 MDL|93957-55-2 SMILES|93957-55-2 sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate