Home Amines 94-16-6
94-16-6,MFCD00150723
Catalog No.:AA003U8H

94-16-6 | Aminohippurate sodium

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1mg
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$6.00   $4.00
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25mg
98%
in stock  
$8.00   $6.00
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100mg
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$11.00   $8.00
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1g
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$93.00   $65.00
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5g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003U8H
Chemical Name:
Aminohippurate sodium
CAS Number:
94-16-6
Molecular Formula:
C9H9N2NaO3
Molecular Weight:
216.1691
MDL Number:
MFCD00150723
SMILES:
NC(C(=O)[O-])NC(=O)c1ccccc1.[Na+]
Properties
Properties
 
BP:
517.2°C at 760 mmHg  
Form:
Solid  
MP:
123-125°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
227  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  

Literature

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Title: Renal effects of carprofen and etodolac in euvolemic and volume-depleted dogs.

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Title: A novel approach for blood purification: mixed-matrix membranes combining diffusion and adsorption in one step.

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Title: A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter.

Journal: American journal of physiology. Cell physiology 20120601

Title: Interaction and transport of kynurenic acid via human organic anion transporters hOAT1 and hOAT3.

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Title: First evidence of epithelial transport in tardigrades: a comparative investigation of organic anion transport.

Journal: The Journal of experimental biology 20120201

Title: A structural and spectroscopic study on para-aminohippuric acid with experimental and theoretical approaches.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120101

Title: Renal expression and function of oat1 and oat3 in rats with vascular calcification.

Journal: Pharmacology 20120101

Title: Metabonomics biomarkers for subacute toxicity screening for benzene exposure in mice.

Journal: Journal of toxicology and environmental health. Part A 20120101

Title: Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3.

Journal: American journal of physiology. Renal physiology 20111101

Title: Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease.

Journal: Kidney international 20110801

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Title: Functional analysis of human sodium-phosphate transporter 4 (NPT4/SLC17A3) polymorphisms.

Journal: Journal of pharmacological sciences 20110101

Title: Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction.

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Title: Contribution of bradykinin B2 receptors to the inhibition by valsartan of systemic and renal effects of exogenous angiotensin II in salt-repleted humans.

Journal: The Journal of pharmacology and experimental therapeutics 20100901

Title: Development and validation of a liquid chromatography-tandem mass spectrometry method for simultaneous quantification of p-aminohippuric acid and inulin in rat plasma for renal function study.

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Title: Glomerular hyperfiltration and increased proximal sodium reabsorption in subjects with type 2 diabetes or impaired fasting glucose in a population of the African region.

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Title: Determination of p-aminohippuric acid in rat plasma by liquid chromatography-tandem mass spectrometry.

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Title: Plasma 25-hydroxyvitamin D and regulation of the renin-angiotensin system in humans.

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Title: Measurement of kidney perfusion by magnetic resonance imaging: comparison of MRI with arterial spin labeling to para-aminohippuric acid plasma clearance in male subjects with metabolic syndrome.

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Title: Major contribution of tubular secretion to creatinine clearance in mice.

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Title: Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability.

Journal: The British journal of nutrition 20100301

Title: Dopamine increases renal oxygenation: a clinical study in post-cardiac surgery patients.

Journal: Acta anaesthesiologica Scandinavica 20100201

Title: Differential effects of clinical doses of antenatal betamethasone on nephron endowment and glomerular filtration rate in adult sheep.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20100201

Title: Renal functional effects of simultaneous bilateral single-tract percutaneous access in pigs.

Journal: BJU international 20100101

Title: Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: Lack of a primary physicochemical determinant in the direct transport of drugs to the brain after nasal administration in rats: potential involvement of transporters in the pathway.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome.

Journal: American journal of physiology. Renal physiology 20091201

Title: Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20091001

Title: Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091001

Title: Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

Journal: Toxicology 20091001

Title: Determination of para-aminohippuric acid (PAH) in human plasma and urine by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

Title: Organic anion transporter OAT1 is involved in renal handling of citrulline.

Journal: American journal of physiology. Renal physiology 20090701

Title: Oral contraceptive progestins and angiotensin-dependent control of the renal circulation in humans.

Journal: Journal of human hypertension 20090601

Title: Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine.

Journal: The Journal of pharmacology and experimental therapeutics 20090401

Title: Effect of CP-690,550, an orally active janus kinase inhibitor, on renal function in healthy adult volunteers.

Journal: Journal of clinical pharmacology 20090401

Title: Dietary fats altered nephrotoxicity profile of methylmercury in rats.

Journal: Journal of applied toxicology : JAT 20090301

Title: Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Calpha.

Journal: American journal of physiology. Endocrinology and metabolism 20090201

Title: Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090201

Title: Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20090201

Title: Expression and functional characterization of choline transporter in human keratinocytes.

Journal: Journal of pharmacological sciences 20090101

Title: [Coupling of Na+/alpha-ketoglutarate symport and PAH/alpha-ketoglutarate antiport in epithelial cells. Estimation of probability of the anion exchanger spontaneous re-orientation].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20090101

Title: The flavonoid quercetin protects and prevents against potassium dichromate-induced systemic peroxidation of lipids and diminution in renal clearance of para-aminohippuric acid and inulin in the rat.

Journal: Drug and chemical toxicology 20090101

Title: Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias.

Journal: Pflugers Archiv : European journal of physiology 20081001

Title: Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081001

Title: Nutrient net absorption across the portal-drained viscera of forage-fed beef steers: Quantitative assessment and application to a nutritional prediction model.

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Title: Cell free expression and functional reconstitution of eukaryotic drug transporters.

Journal: Biochemistry 20080415

Title: Inhibition of carrier-mediated uptake of epirubicin reduces cytotoxicity in primary culture of rat hepatocytes.

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Title: Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics.

Journal: American journal of physiology. Renal physiology 20080401

Title: Functional analysis of phenolsulfonphthalein transport system in Long-Evans Cinnamon rats.

Journal: Biochimica et biophysica acta 20080101

Title: Upregulation of rat renal cortical organic anion transporter (OAT1 and OAT3) expression in response to ischemia/reperfusion injury.

Journal: American journal of nephrology 20080101

Title: Segment-specific proximal tubule injury in tripterygium glycosides intoxicated rats.

Journal: Journal of biochemical and molecular toxicology 20080101

Title: Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201

Title: The effect of oral contraceptives on the nitric oxide system and renal function.

Journal: American journal of physiology. Renal physiology 20071101

Title: Rat organic solute carrier protein 1 (rOscp1) mediated the transport of organic solutes in Xenopus laevis oocytes: isolation and pharmacological characterization of rOscp1.

Journal: Life sciences 20070922

Title: Possible involvement of organic anion and cation transporters in renal excretion of xanthine derivatives, 3-methylxanthine and enprofylline.

Journal: Life sciences 20070922

Title: Involvement of carrier-mediated transport system in uptake of tetrodotoxin into liver tissue slices of puffer fish Takifugu rubripes.

Journal: Toxicon : official journal of the International Society on Toxinology 20070801

Title: In situ kinetic modelling of intestinal efflux in rats: functional characterization of segmental differences and correlation with in vitro results.

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Title: Cl- -dependent upregulation of human organic anion transporters: different effects on transport kinetics between hOAT1 and hOAT3.

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Title: Isolation and characterization of polyspecific mouse organic solute carrier protein 1 (mOscp1).

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Title: Alteration in renal organic anion transporter 1 after ischemia/reperfusion in cadaveric renal allografts.

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Title: Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.

Journal: American journal of physiology. Renal physiology 20070501

Title: Effects of brimonidine ingestion on cardiovascular responses and renal function in conscious dogs.

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Journal: The Journal of pharmacology and experimental therapeutics 20070401

Title: Progesterone inhibits folic acid transport in human trophoblasts.

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Title: Differences in decline in GFR with age between males and females. Reference data on clearances of inulin and PAH in potential kidney donors.

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Journal: American journal of physiology. Renal physiology 20060801

Title: Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3.

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Title: Handling of the homocysteine S-conjugate of methylmercury by renal epithelial cells: role of organic anion transporter 1 and amino acid transporters.

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Title: Intestinal renal metabolism of L-citrulline and L-arginine following enteral or parenteral infusion of L-alanyl-L-[2,15N]glutamine or L-[2,15N]glutamine in mice.

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Title: Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1.

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Title: Isolation and functional characterization of a novel organic solute carrier protein, hOSCP1.

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Title: Transport of N-acetylcysteine s-conjugates of methylmercury in Madin-Darby canine kidney cells stably transfected with human isoform of organic anion transporter 1.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Renin release in response to Renin system blockade: activation of the Renin system in type 1 diabetes mellitus.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20050901

Title: Structure-affinity relationship in the interactions of human organic anion transporter 1 with caffeine, theophylline, theobromine and their metabolites.

Journal: Biochimica et biophysica acta 20050815

Title: Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).

Journal: The Journal of pharmacology and experimental therapeutics 20050801

Title: A summary of recent findings on birth outcomes and developmental effects of prenatal ETS, PAH, and pesticide exposures.

Journal: Neurotoxicology 20050801

Title: Determination of uric acid and p-aminohippuric acid in human saliva and urine using capillary electrophoresis with electrochemical detection: potential application in fast diagnosis of renal disease.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050725

Title: Immunocytochemical characterization of the incubated rat renal cortical slices.

Journal: Pflugers Archiv : European journal of physiology 20050701

Title: Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney.

Journal: Experimental & molecular medicine 20050630

Title: Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slices.

Journal: Pharmaceutical research 20050601

Title: Functional expression of pig renal organic anion transporter 3 (pOAT3).

Journal: Biochimie 20050501

Title: Altered renal elimination of organic anions in rats with chronic renal failure.

Journal: Biochimica et biophysica acta 20050415

Title: Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats.

Journal: Pharmaceutical research 20050401

Title: Molecular cloning and functional analyses of OAT1 and OAT3 from cynomolgus monkey kidney.

Journal: Pharmaceutical research 20050401

Title: Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).

Journal: Pharmacogenetics and genomics 20050401

Title: Reduced plasma total homocysteine concentrations in Type 1 diabetes mellitus is determined by increased renal clearance.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050301

Title: Characterization of secretory intestinal transport of phenolsulfonphthalein.

Journal: Drug metabolism and pharmacokinetics 20050201

Title: Segmentary effects on the renal proximal tubule due to hexachloro-1,3-butadiene in rats: biomarkers related to gender.

Journal: Journal of applied toxicology : JAT 20050101

Title: Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20041201

Title: Regulation of renal adenosine excretion in humans--role of sodium and fluid homeostasis.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101

Title: Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter.

Journal: Journal of the American Society of Nephrology : JASN 20041101

Title: Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).

Journal: European journal of pharmacology 20041025

Title: The legacy of Homer W. Smith: mechanistic insights into renal physiology.

Journal: The Journal of clinical investigation 20041015

Title: Vagal cooling and concomitant portal norepinephrine infusion do not reduce net hepatic glucose uptake in conscious dogs.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20041001

Title: Characterization of renal excretion mechanism for a novel diuretic, M17055, in rats.

Journal: Journal of pharmaceutical sciences 20041001

Title: Protective effect of resveratrol against 6-hydroxydopamine-induced impairment of renal p-aminohippurate transport.

Journal: Archives of toxicology 20040901

Title: The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules.

Journal: Journal of the American Society of Nephrology : JASN 20040801

Title: Homocysteine and the renal epithelial transport and toxicity of inorganic mercury: role of basolateral transporter organic anion transporter 1.

Journal: Journal of the American Society of Nephrology : JASN 20040801

Title: Human organic anion transporter 1 mediates cellular uptake of cysteine-S conjugates of inorganic mercury.

Journal: Kidney international 20040701

Title: Renal secretion of the antiviral nucleoside analog AM188 is inhibited by probenecid, p-aminohippuric acid, and cimetidine in the isolated perfused rat kidney.

Journal: Pharmaceutical research 20040601

Title: Severe hyperglycemia: a determinant factor for hypofiltration in alloxan diabetic rats.

Journal: Acta diabetologica 20040601

Title: Measurement of glomerular filtration rate, renal plasma flow, and endogenous creatinine clearance in cheetahs (Acinonyx jubatus jubatus).

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20040601

Title: Cysteine residues in the organic anion transporter mOAT1.

Journal: The Biochemical journal 20040515

Title: Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice.

Journal: American journal of physiology. Renal physiology 20040501

Title: Renal elimination of organic anions in rats with bilateral ureteral obstruction.

Journal: Biochimica et biophysica acta 20040405

Title: Action of EGF and PGE2 on basolateral organic anion uptake in rabbit proximal renal tubules and hOAT1 expressed in human kidney epithelial cells.

Journal: American journal of physiology. Renal physiology 20040401

Title: Expression studies and functional characterization of renal human organic anion transporter 1 isoforms.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040401

Title: ARF in children with minimal change nephrotic syndrome may be related to functional changes of the glomerular basal membrane.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20040301

Title: Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.

Journal: Journal of pharmacological sciences 20040301

Title: A new HPLC method to determine glomerular filtration rate and effective renal plasma flow in conscious dogs by single intravenous administration of iohexol and p-aminohippuric acid.

Journal: Journal of chromatographic science 20040201

Title: Interaction of the metal chelator DMPS with OAT1 and OAT3 in intact isolated rabbit renal proximal tubules.

Journal: American journal of physiology. Renal physiology 20040101

Title: Characterization of uremic toxin transport by organic anion transporters in the kidney.

Journal: Kidney international 20040101

Title: Subpressor dose asymmetric dimethylarginine modulates renal function in humans through nitric oxide synthase inhibition.

Journal: Kidney & blood pressure research 20040101

Title: On the role of the kidneys in the pathogenesis of edema formation during permanent morphine application/an experimental study in rats.

Journal: Arzneimittel-Forschung 20040101

Title: Peroxisome proliferator-activated receptor [gamma] agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: Effect of chronic accumulation of aluminum on renal function, cortical renal oxidative stress and cortical renal organic anion transport in rats.

Journal: Archives of toxicology 20031101

Title: Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells.

Journal: American journal of physiology. Renal physiology 20031001

Title: Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization.

Journal: Journal of the American Society of Nephrology : JASN 20030801

Title: Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.

Journal: The Journal of biological chemistry 20030725

Title: Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20030701

Title: Nonionic contrast media are less nephrotoxic than ionic contrast media to rat renal cortical slices.

Journal: Toxicology letters 20030605

Title: Compensation increase in organic anion excretion in rats with acute biliary obstruction: role of the renal organic anion transporter 1.

Journal: Pharmacology 20030601

Title: Vasodilator effects of L-arginine are stereospecific and augmented by insulin in humans.

Journal: American journal of physiology. Endocrinology and metabolism 20030601

Title: Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601

Title: Use of gene chip technology for the characterisation of the regulation of renal transport processes and of nephrotoxicity in rats.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601

Title: Inhibition of gluconeogenesis and p-aminohipuric acid accumulation in rat renal cortical slices by ionic and nonionic contrast media.

Journal: Clinical and experimental nephrology 20030601

Title: Assessment of experimentally induced acute changes of renal haemodynamics.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030501

Title: Impairment of the renal p-aminohippurate transport induced by 6-hydroxydopamine.

Journal: The Journal of pharmacy and pharmacology 20030501

Title: Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.

Journal: American journal of physiology. Renal physiology 20030401

Title: Capillary electrophoresis method to measure p-aminohippuric acid in urine and plasma for the assessment of renal plasma flow.

Journal: Clinical chemistry 20030401

Title: Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030401

Title: Increased plasma concentration and brain penetration of methamphetamine in behaviorally sensitized rats.

Journal: European journal of pharmacology 20030307

Title: Liquid chromatography for iothalamate in biological samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305

Title: Glomerular ultrafiltration in normal and preeclamptic pregnancy.

Journal: Journal of the American Society of Nephrology : JASN 20030301

Title: Impaired tubular excretory function as a late renal side effect of chemotherapy in children.

Journal: Journal of pediatric hematology/oncology 20030301

Title: Role of BSP/bilirubin binding protein on p-aminohippurate transport in rat kidney.

Journal: Molecular and cellular biochemistry 20030301

Title: Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030214

Title: Effect of feed intake on amino acid transfers across the ovine hindquarters.

Journal: The British journal of nutrition 20030201

Title: Inhibition of basolateral transport and cellular accumulation of cDDP and N-acetyl- L-cysteine-cDDP by TEA and PAH in the renal proximal tubule.

Journal: Cancer chemotherapy and pharmacology 20030201

Title: Urate transport via human PAH transporter hOAT1 and its gene structure.

Journal: Kidney international 20030101

Title: Clearance studies in genetically altered mice.

Journal: Methods in molecular medicine 20030101

Title: Brain efflux index method. Characterization of efflux transport across the blood-brain barrier.

Journal: Methods in molecular medicine 20030101

Title: Renal nerves mediate changes in contralateral renal blood flow after extracorporeal shockwave lithotripsy.

Journal: Nephron. Physiology 20030101

Title: Pitfalls of single-sample determination of renal clearance.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021201

Title: p-Aminohippurate transport at the apical membrane in the OK kidney epithelial cell line.

Journal: Pharmaceutical research 20021201

Title: The adverse renal effects of prostaglandin-synthesis inhibitors in the newborn rabbit.

Journal: Seminars in perinatology 20021201

Title: Cloning of the pig renal organic anion transporter 1 (pOAT1).

Journal: Biochimie 20021201

Title: Interaction of the metal chelator 2,3-dimercapto-1-propanesulfonate with the rabbit multispecific organic anion transporter 1 (rbOAT1).

Journal: Molecular pharmacology 20021101

Title: Renal functional reserve is well maintained in patients with advanced liver cirrhosis and ascites.

Journal: Scandinavian journal of gastroenterology 20021101

Title: Urate/alpha-ketoglutarate exchange in avian basolateral membrane vesicles.

Journal: American journal of physiology. Cell physiology 20021001

Title: Facilitated diffusion of urate in avian brush-border membrane vesicles.

Journal: American journal of physiology. Cell physiology 20021001

Title: Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain.

Journal: Journal of neurochemistry 20021001

Title: Effects of Juglans sinensis Dode extract and antioxidant on mercury chloride-induced acute renal failure in rabbits.

Journal: Journal of ethnopharmacology 20020901

Title: Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy.

Journal: Kidney international 20020801

Title: Rapid microplate method for PAH estimation.

Journal: American journal of physiology. Renal physiology 20020801

Title: Short-term regulation of basolateral organic anion uptake in proximal tubular OK cells: EGF acts via MAPK, PLA(2), and COX1.

Journal: Journal of the American Society of Nephrology : JASN 20020801

Title: Renal organic anion transport system: a mechanism for the basolateral uptake of mercury-thiol conjugates along the pars recta of the proximal tubule.

Journal: Toxicology and applied pharmacology 20020801

Title: Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

Journal: The Journal of biological chemistry 20020726

Title: Role of aromatic transmembrane residues of the organic anion transporter, rOAT3, in substrate recognition.

Journal: Biochemistry 20020716

Title: Expression and function of sodium transporters in two opossum kidney cell clonal sublines.

Journal: American journal of physiology. Renal physiology 20020701

Title: Evaluation of renal function in transplant patients on tacrolimus therapy.

Journal: Journal of clinical pharmacology 20020701

Title: Renal interstitial fibrosis (RIF): II. Ultrasound follow up study of single uranyl nitrate administration causing renal dysfunction in rats--comparison with histologic and functional renal parameters.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020701

Title: Confocal imaging of organic anion transport in intact rat choroid plexus.

Journal: American journal of physiology. Renal physiology 20020501

Title: Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus.

Journal: Molecular pharmacology 20020501

Title: Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.

Journal: Kidney international 20020501

Title: Renal hemodynamic effects of somatostatin are not related to inhibition of endogenous insulin release.

Journal: Kidney international 20020501

Title: Fenoldopam mesylate blocks reductions in renal plasma flow after radiocontrast dye infusion: a pilot trial in the prevention of contrast nephropathy.

Journal: American heart journal 20020501

Title: Increased renal expression of bilirubin glucuronide transporters in a rat model of obstructive jaundice.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020401

Title: Endothelin ETA receptor-subtype specific antagonism does not mitigate the acute systemic or renal effects of exogenous angiotensin II in humans.

Journal: European journal of clinical investigation 20020401

Title: Sex differences in p-aminohippuric acid transport in rat kidney: role of membrane fluidity and expression of OAT1.

Journal: Molecular and cellular biochemistry 20020401

Title: Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions.

Journal: The Journal of pharmacology and experimental therapeutics 20020301

Title: Acute and long-term effects of ACE inhibition on renal haemodynamics in glomerular and interstitial nephropathies.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20020301

Title: Effects of gender on the pharmacokinetics of drugs secreted by the renal organic anions transport systems in the rat.

Journal: Pharmacological research 20020201

Title: The distribution of the anti-HIV drug, 2'3'-dideoxycytidine (ddC), across the blood-brain and blood-cerebrospinal fluid barriers and the influence of organic anion transport inhibitors.

Journal: Journal of neurochemistry 20020201

Title: The anti-influenza drug oseltamivir exhibits low potential to induce pharmacokinetic drug interactions via renal secretion-correlation of in vivo and in vitro studies.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101

Title: Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.

Journal: British journal of pharmacology 20020101

Title: Comparison of bidirectional cephalexin transport across MDCK and caco-2 cell monolayers: interactions with peptide transporters.

Journal: Pharmaceutical research 20020101

Title: Molecular characterization of the renal organic anion transporter 1.

Journal: Cell biochemistry and biophysics 20020101

Title: Isolated lung chemotherapeutic infusions for treatment of pulmonary metastases: a pilot study.

Journal: Journal of biomedical science 20020101

Title: [The value and adaptability of glomerular filtration rate and reserve test (review of the literature)].

Journal: Medicina (Kaunas, Lithuania) 20020101

Title: Transport of anionic drugs across the basolateral membrane of proximal S2 segments of the rabbit kidney. Inverse relationship between the affinity to the p-aminohippurate transport system and the transport rate.

Journal: Arzneimittel-Forschung 20020101

Title: Alternative high-performance liquid chromatographic assay for p-aminohippuric acid (PAH): effect of aging on PAH excretion in the isolated perfused rat kidney.

Journal: Journal of pharmaceutical and biomedical analysis 20011201

Title: Effect of angiotensin-converting enzyme inhibitor on renal function in ovarian hyperstimulation syndrome in the rabbit.

Journal: Fertility and sterility 20011201

Title: Interaction of 2,3-dimercapto-1-propane sulfonate with the human organic anion transporter hOAT1.

Journal: The Journal of pharmacology and experimental therapeutics 20011101

Title: Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1.

Journal: Molecular pharmacology 20011101

Title: Tubular segment-specific biomarkers of nephrotoxicity in the rat.

Journal: Toxicology letters 20011015

Title: Cationic amino acids involved in dicarboxylate binding of the flounder renal organic anion transporter.

Journal: Journal of the American Society of Nephrology : JASN 20011001

Title: Renal hemodynamic effect of tacrolimus in renal transplanted children.

Journal: Pediatric nephrology (Berlin, Germany) 20011001

Title: Impairment of renal vasodilation with l-arginine is related to more severe disease in untreated hypertensive patients.

Journal: Hypertension (Dallas, Tex. : 1979) 20011001

Title: Adenine nucleotide and calpain inhibitor I protect against atractyloside-induced toxicity in rat renal cortical slices in vitro.

Journal: Archives of toxicology 20011001

Title: Mild to severe lithium-induced nephropathy models and urine N-acetyl-beta-D-glucosaminidase in rats.

Journal: Methods and findings in experimental and clinical pharmacology 20011001

Title: Effect of steviol on para-aminohippurate transport by isolated perfused rabbit renal proximal tubule.

Journal: The Journal of pharmacology and experimental therapeutics 20010901

Title: Hypertension after neonatal uninephrectomy in rats precedes glomerular damage.

Journal: Hypertension (Dallas, Tex. : 1979) 20010901

Title: Characterization of the mechanisms involved in the gender differences in p-aminohippurate renal elimination in rats.

Journal: Canadian journal of physiology and pharmacology 20010901

Title: Effects of different nickel compounds on the transport of para-aminohippurate ion by rat renal cortical slices.

Journal: Toxicology letters 20010706

Title: High-throughput multi-analyte screening for renal disease using capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20010701

Title: Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.

Journal: The Journal of pharmacology and experimental therapeutics 20010701

Title: Salviae radix extract prevents cisplatin-induced acute renal failure in rabbits.

Journal: Nephron 20010701

Title: Molecular physiology of renal p-aminohippurate secretion.

Journal: News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 20010601

Title: Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3.

Journal: Biochemistry 20010508

Title: Isolation of a family of organic anion transporters from human liver and kidney.

Journal: Biochemical and biophysical research communications 20010504

Title: Sodium retention in preascitic stage of cirrhosis.

Journal: Seminars in nephrology 20010501

Title: Transport of levofloxacin in the OK kidney epithelial cell line: interaction with p-aminohippurate transport.

Journal: Pharmaceutical research 20010501

Title: Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo).

Journal: European journal of pharmacology 20010413

Title: Effect of oral contraceptives on the renin angiotensin system and renal function.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010301

Title: Simultaneous determination of inulin and p-aminohippuric acid in plasma and urine by reversed-phase high-performance liquid chromatography.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010210

Title: Progress in understanding human ischemic acute renal failure.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010201

Title: Characterization of tubular functional capacity in humans using para-aminohippurate and famotidine.

Journal: Kidney international 20010101

Title: Organic anion transport across the choroid plexus.

Journal: Microscopy research and technique 20010101

Title: Secretory transport of p-aminohippuric acid across intestinal epithelial cells in Caco-2 cells and isolated intestinal tissue.

Journal: The Journal of pharmacy and pharmacology 20010101

Title: Renal function, sodium and water homeostasis in patients with idiopathic extrahepatic portal vein thrombosis compared with normal healthy controls.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20010101

Title: Modulation by cyclic AMP and phorbol myristate acetate of cephaloridine-induced injury in rat renal cortical slices.

Journal: Japanese journal of pharmacology 20010101

Title: The hippurate ratio as an indicator of functional hepatic reserve for resection of hepatocellular carcinoma in cirrhotic patients.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20010101

Title: Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide?

Journal: Kidney & blood pressure research 20010101

Title: Oxidative stress and renal dysfunction in salt-sensitive hypertension.

Journal: Kidney & blood pressure research 20010101

Title: Historical control data on urinary and renal tissue biomarkers in naive male Wistar rats.

Journal: Journal of applied toxicology : JAT 20010101

Title: Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity.

Journal: Toxicology and applied pharmacology 19991201

Title: Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity.

Journal: Kidney international 19991201

Title: Renal dysfunction associated with the perioperative use of diclofenac.

Journal: Anesthesia and analgesia 19991001

Title: Transport of ochratoxin A by renal multispecific organic anion transporter 1.

Journal: The Journal of pharmacology and experimental therapeutics 19990601

Title: Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.

Journal: The Journal of biological chemistry 19990507

Title: Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension.

Journal: Journal of the American Society of Nephrology : JASN 19981201

Title: Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthione against hexachloro-1,3-butadiene-induced nephrotoxicity.

Journal: Toxicology and applied pharmacology 19960701

Title: Evaluation of the single-injection plasma disappearance of technetium-99m mercaptoacetyltriglycine method for determination of effective renal plasma flow in dogs with normal or abnormal renal function.

Journal: American journal of veterinary research 19941201

Title: Glutathione status, lipid peroxidation and kidney function in streptozotocin diabetic rats.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 19940701

Title: Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells.

Journal: Carcinogenesis 19940401

Title: The nephrotoxicity, cytotoxicity and renal handling of a cisplatin-methionine complex in male Wistar rats.

Journal: Toxicology 19940325

Title: Susceptibility of ageing kidney to quinidine.

Journal: Pharmacological research 19940101

Title: Caffeine attenuates the renal vascular response to angiotensin II infusion.

Journal: Hypertension (Dallas, Tex. : 1979) 19931201

Title: Effects of diltiazem on netilmicin-induced nephrotoxicity in rabbits.

Journal: Antimicrobial agents and chemotherapy 19930901

Title: Acute hepatic and renal toxicity of dichlorobenzene isomers in Fischer 344 rats.

Journal: Journal of applied toxicology : JAT 19930101

Title: Intrinsic susceptibility of the kidney to acetaminophen toxicity in middle-aged rats.

Journal: Toxicology letters 19900601

Title: Effects of acute and chronic acyclovir on canine renal function.

Journal: The Journal of pharmacology and experimental therapeutics 19890501

Title: Effect of alkylxanthines on gentamicin-induced acute renal failure in the rat.

Journal: The Journal of pharmacy and pharmacology 19881201

Title: Nephrotoxicity of butylated hydroxytoluene in phenobarbital-pretreated male rats.

Journal: Archives of toxicology 19880401

Title: [Acute reversible kidney insufficiency due to enalapril during diuretic-treated heart insufficiency].

Journal: Deutsche medizinische Wochenschrift (1946) 19870612

Title: Urinary tract effects of phensuximide in the Sprague-Dawley and Fischer 344 rat.

Journal: Journal of applied toxicology : JAT 19861001

Title: Structure/activity studies of the nephrotoxic and mutagenic action of cysteine conjugates of chloro- and fluoroalkenes.

Journal: Chemico-biological interactions 19850601

Title: Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity.

Journal: The Journal of laboratory and clinical medicine 19821001

Title: Aspirin-induced depression of glomerular filtration rate in normal humans: role of sodium balance.

Journal: Annals of internal medicine 19810301

Title: Corticoid effects on angiotensin- and norepinephrine-induced proteinuria in rats.

Journal: The American journal of physiology 19790801

Title: Nephrotoxic and hepatotoxic effects of triclosan and chlorhexidine in rats.

Journal: Toxicology and applied pharmacology 19771001

Title: Naidoo V, et al. Diclofenac toxicity in Gyps vulture is associated with decreased uric acid excretion and not renal portal vasoconstriction. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Apr;149(3):269-74.

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Tags:94-16-6 Molecular Formula|94-16-6 MDL|94-16-6 SMILES|94-16-6 Aminohippurate sodium