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940-62-5,MFCD00004396
Catalog No.:AA00GRLK

940-62-5 | 4-CHLOROCINNAMIC ACID

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5g
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10g
95%
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25g
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$15.00   $11.00
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100g
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500g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00GRLK
Chemical Name:
4-CHLOROCINNAMIC ACID
CAS Number:
940-62-5
Molecular Formula:
C9H7ClO2
Molecular Weight:
182.6037
MDL Number:
MFCD00004396
SMILES:
OC(=O)/C=C/c1ccc(cc1)Cl
Properties
Computed Properties
 
Complexity:
181  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.4  

Downstream Synthesis Route

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[5]JournaloftheIndianChemicalSociety,2011,vol.88,p.405-414

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[7]SyntheticCommunications,2010,vol.40,p.1915-1919

[8]IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,2011,vol.50,p.1479-1483

[9]Arkivoc,2016,vol.2016,p.284-296

[10]JournalofChemicalResearch,2005,p.364-365

[11]EuropeanJournalofOrganicChemistry,2020,vol.2020,p.878-883

[12]JournalofChemicalResearch,2011,vol.35,p.723-725

[13]ChineseChemicalLetters,2016,vol.27,p.555-558

[14]BioorganicandMedicinalChemistryLetters,2016,vol.26,p.1849-1853

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[18]Tetrahedron,2007,vol.63,p.960-965

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[22]JournalofMedicinalChemistry,2019,vol.62,p.7264-7288

[23]EuropeanJournalofMedicinalChemistry,2019,vol.183

[24]EuropeanJournalofMedicinalChemistry,2017,vol.135,p.382-391

[25]JournalofOrganicChemistry,2020,vol.85,p.5183-5192

[26]JournalofOrganicChemistryUSSR(EnglishTranslation),1989,vol.25,p.1694-1699    ZhurnalOrganicheskoiKhimii,1989,vol.25,p.1876-1881

[27]Proceedings-IndianAcademyofSciences,SectionA,1941,vol.14,p.116-120    Chem.Abstr.,1942,p.1599

[28]JournaloftheAmericanChemicalSociety,1947,vol.69,p.852

[29]JournaloftheChemicalSociety,1930,p.968,979

[30]Heterocycles,1994,vol.37,p.1495-1502

[31]EuropeanJournalofMedicinalChemistry,2002,vol.37,p.961-972

[32]EuropeanJournalofMedicinalChemistry,2002,vol.37,p.979-984

[33]BioorganicandMedicinalChemistry,2010,vol.18,p.4991-4996

[34]AdvancedSynthesisandCatalysis,2011,vol.353,p.871-878

[35]BioorganicandMedicinalChemistry,2011,vol.19,p.4730-4738

[36]BioorganicandMedicinalChemistry,2011,vol.19,p.5012-5022

[37]TetrahedronLetters,2011,vol.52,p.4906-4910

[38]ChineseJournalofChemistry,2011,vol.29,p.2394-2400

[39]ChemicalBiologyandDrugDesign,2013,vol.81,p.275-283

[40]Chemistry-AEuropeanJournal,2013,vol.19,p.3833-3837

[41]BioorganicandMedicinalChemistryLetters,2013,vol.23,p.2876-2879

[42]EuropeanJournalofMedicinalChemistry,2014,vol.81,p.420-426

[43]AngewandteChemie-InternationalEdition,2014,vol.53,p.7918-7922    Angew.Chem.,2014,vol.53,p.8052-8056,5

[44]SouthAfricanJournalofChemistry,2014,vol.67,p.214-217

[45]EuropeanJournalofMedicinalChemistry,2015,vol.97,p.32-41

[46]EuropeanJournalofMedicinalChemistry,2015,vol.103,p.506-515

[47]AsianJournalofChemistry,2016,vol.28,p.1895-1898

[48]Tetrahedron,2016,vol.72,p.7256-7262

[49]OrganicandBiomolecularChemistry,2017,vol.15,p.7272-7276

[50]BioorganicandMedicinalChemistry,2017,vol.25,p.5726-5732

[51]ArchivderPharmazie,2018,vol.351

[52]Synthesis,2018,vol.50,p.184-192

[53]MedicinalChemistryResearch,2018,vol.27,p.1366-1373

[54]AngewandteChemie-InternationalEdition,2018,vol.57,p.9279-9283    Angew.Chem.,2018,vol.130,p.9423-9427,5

[55]ChemMedChem,2018,vol.13,p.1517-1529

[56]Patent:CN110317136,2019,A.Locationinpatent:Paragraph0080;0081;0083

Literature

Title: Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

Journal: Bioorganic & medicinal chemistry letters 20110501

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Structure-activity relationships of trans-cinnamic acid derivatives on alpha-glucosidase inhibition.

Journal: Bioorganic & medicinal chemistry letters 20040607

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