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94105-90-5,MFCD00016662
Catalog No.:AA005V1X

94105-90-5 | Equol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
96%
in stock  
$13.00   $9.00
- +
5g
96%
in stock  
$27.00   $19.00
- +
100g
96%
in stock  
$384.00   $269.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005V1X
Chemical Name:
Equol
CAS Number:
94105-90-5
Molecular Formula:
C15H14O3
Molecular Weight:
242.2699
MDL Number:
MFCD00016662
SMILES:
Oc1ccc(cc1)C1COc2c(C1)ccc(c2)O
NSC Number:
670882
Properties
Properties
 
BP:
441.7 °C at 760 mmHg  
Form:
Solid  
MP:
158-160?C  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
273  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:BRIGHAMYOUNGUNIVERSITY;CINCINNATICHILDREN'SHOSPITALMEDICALCENTER;COLORADOSTATEUNIVERSITYSYSTEM-WO2008/20853,2008,A1Locationinpatent:Page/Pagecolumn38-39

[2]Locationinpatent:experimentalpartMinekawa,Takayuki;Kambegawa,Akira;Shindome,Kumiko;Ohkuma,Hiroshi;Abe,Katsushi;Maekawa,Hiroaki;Arakawa,Hidetoshi[ChemicalandPharmaceuticalBulletin,2011,vol.59,#1,p.84-87]

[3]Li,Yuanyuan;Li,Qiang;Zhu,Nan;Gao,Zhuxian;Ma,Yulong[Chirality,2018,vol.30,#8,p.996-1004]

Literature

Title: Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles in vitro.

Journal: Toxicology and applied pharmacology 20160315

Title: The inhibitory effect of black soybean on hepatic cholesterol accumulation in high cholesterol and high fat diet-induced non-alcoholic fatty liver disease.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131001

Title: Effects of the natural endocrine disruptor equol on the pituitary function in adult male rats.

Journal: Toxicology 20130208

Title: Bioavailability of glycitein relatively to other soy isoflavones in healthy young Caucasian men.

Journal: Food chemistry 20121201

Title: Profiling and identification of the metabolites of calycosin in rat hepatic 9000×g supernatant incubation system and the metabolites of calycosin-7-O-β-D-glucoside in rat urine by HPLC-DAD-ESI-IT-TOF-MS(n) technique.

Journal: Journal of pharmaceutical and biomedical analysis 20121101

Title: Interaction effects between genes involved in the AKT signaling pathway and phytoestrogens in gastric carcinogenesis: a nested case-control study from the Korean Multi-Center Cancer Cohort.

Journal: Molecular nutrition & food research 20121101

Title: Effect of 17β-estradiol and flavonoids on the regulation of expression of newly identified oestrogen responsive genes in a rat raphe nuclei-derived cell line.

Journal: Journal of cellular physiology 20121001

Title: Epigenetic modulation of BRCA1 and BRCA2 gene expression by equol in breast cancer cell lines.

Journal: The British journal of nutrition 20121001

Title: Epidemiological profiles between equol producers and nonproducers: a genomewide association study of the equol-producing phenotype.

Journal: Genes & nutrition 20121001

Title: Urinary isoflavonoids and risk of coronary heart disease.

Journal: International journal of epidemiology 20121001

Title: Endocrine disrupting chemicals in urine of Japanese male partners of subfertile couples: a pilot study on exposure and semen quality.

Journal: International journal of hygiene and environmental health 20120901

Title: Analysis of regulatory mechanisms of an insulin-inducible SHARP-2 gene by (S)-Equol.

Journal: Archives of biochemistry and biophysics 20120901

Title: Urinary estrogen metabolites in two soy trials with premenopausal women.

Journal: European journal of clinical nutrition 20120901

Title: Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models.

Journal: Human gene therapy 20120901

Title: Synergistic effect of isoflavone glycosides and fructooligosaccharides on postgastrectomy osteopenia in rats.

Journal: Journal of clinical biochemistry and nutrition 20120901

Title: The effect of equol injection in ovo on lipid metabolism and hepatic lipogenic gene expression in broilers.

Journal: Animal : an international journal of animal bioscience 20120901

Title: Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort.

Journal: European journal of clinical nutrition 20120801

Title: Effects of feeding dairy cows different legume-grass silages on milk phytoestrogen concentration.

Journal: Journal of dairy science 20120801

Title: [Microbial conversion of daidzein affects fecal equol concentration and bacterial composition of rats with or without ovariectomy].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20120704

Title: Reproductive endocrine disruption in smallmouth bass (Micropterus dolomieu) in the Potomac River basin: spatial and temporal comparisons of biological effects.

Journal: Environmental monitoring and assessment 20120701

Title: Photoimmune protective effect of the phytoestrogenic isoflavonoid equol is partially due to its antioxidant activities.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120701

Title: Prediagnostic concentrations of plasma genistein and prostate cancer risk in 1,605 men with prostate cancer and 1,697 matched control participants in EPIC.

Journal: Cancer causes & control : CCC 20120701

Title: Aquatic photochemistry of isoflavone phytoestrogens: degradation kinetics and pathways.

Journal: Environmental science & technology 20120619

Title: Foetal exposure to phthalate esters and anogenital distance in male newborns.

Journal: International journal of andrology 20120601

Title: Equol production changes over time in postmenopausal women.

Journal: The Journal of nutritional biochemistry 20120601

Title: Does equol production determine soy endocrine effects?

Journal: European journal of nutrition 20120601

Title: Prostate cancer chemoprevention by soy isoflavones: role of intestinal bacteria as the 'second human genome'.

Journal: Cancer science 20120601

Title: Elucidation of the metabolic pathway of S-equol in rat, monkey and man.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601

Title: Editorial comment to involvement of estrogen receptors in prostatic diseases.

Journal: International journal of urology : official journal of the Japanese Urological Association 20120601

Title: Circulating isoflavonoid levels in CD-1 mice: effect of oral versus subcutaneous delivery and frequency of administration.

Journal: The Journal of nutritional biochemistry 20120501

Title: Effect of physiological levels of phytoestrogens on mouse oocyte maturation in vitro.

Journal: Cytotechnology 20120501

Title: Proliferative effect of whey from cows' milk varying in phyto-oestrogens in human breast and prostate cancer cells.

Journal: The Journal of dairy research 20120501

Title: Toxicokinetics and lack of uterotropic effect of orally administered S-equol.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Title: Equol production changes over time in pre-menopausal women.

Journal: The British journal of nutrition 20120401

Title: Soy isoflavones and cardiovascular disease epidemiological, clinical and -omics perspectives.

Journal: Current pharmaceutical biotechnology 20120401

Title: 2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.

Journal: Bioorganic & medicinal chemistry 20120401

Title: The effects of natural S-equol supplementation on skin aging in postmenopausal women: a pilot randomized placebo-controlled trial.

Journal: Menopause (New York, N.Y.) 20120201

Title: Urinary estrogen metabolites during a randomized soy trial.

Journal: Nutrition and cancer 20120201

Title: [Phytoestrogenes in menopause: working mechanisms and clinical results in 28 patients].

Journal: Ceska gynekologie 20120201

Title: Medicarpin, a legume phytoalexin, stimulates osteoblast differentiation and promotes peak bone mass achievement in rats: evidence for estrogen receptor β-mediated osteogenic action of medicarpin.

Journal: The Journal of nutritional biochemistry 20120101

Title: Long-term treatment of ovariectomized mice with estradiol or phytoestrogens as a new model to study the role of estrogenic substances in the heart.

Journal: Planta medica 20120101

Title: Prostate cancer chemoprevention study: an investigative randomized control study using purified isoflavones in men with rising prostate-specific antigen.

Journal: Cancer science 20120101

Title: A natural S-equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women.

Journal: Journal of women's health (2002) 20120101

Title: Phytoestrogen biomonitoring: an extractionless LC-MS/MS method for measuring urinary isoflavones and lignans by use of atmospheric pressure photoionization (APPI).

Journal: Analytical and bioanalytical chemistry 20120101

Title: The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.

Journal: Journal of oncology 20120101

Title: Human excretion of bisphenol A: blood, urine, and sweat (BUS) study.

Journal: Journal of environmental and public health 20120101

Title: Biochemical investigation and gene analysis of equol: a plant and soy-derived isoflavonoid with antiaging and antioxidant properties with potential human skin applications.

Journal: BioFactors (Oxford, England) 20120101

Title: Genetic susceptibility on CagA-interacting molecules and gene-environment interaction with phytoestrogens: a putative risk factor for gastric cancer.

Journal: PloS one 20120101

Title: Improvements of insulin resistance in ovariectomized rats by a novel phytoestrogen from Curcuma comosa Roxb.

Journal: BMC complementary and alternative medicine 20120101

Title: Correlations of urinary phytoestrogen excretion with lifestyle factors and dietary intakes among middle-aged and elderly Chinese women.

Journal: International journal of molecular epidemiology and genetics 20120101

Title: Differential effects of short term feeding of a soy protein isolate diet and estrogen treatment on bone in the pre-pubertal rat.

Journal: PloS one 20120101

Title: The Interplay between Estrogen and Fetal Adrenal Cortex.

Journal: Journal of nutrition and metabolism 20120101

Title: Mechanism of phytoestrogen action in Leydig cells of ganders (Anser anser domesticus): Interaction with estrogen receptors and steroidogenic enzymes.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101

Title: The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth.

Journal: Molecular cancer 20120101

Title: Influence of fructooligosaccharide on pharmacokinetics of isoflavones in postmenopausal women.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Phytoestrogens in human pregnancy.

Journal: Obstetrics and gynecology international 20120101

Title: Quantitative and qualitative analysis of the antifungal activity of allicin alone and in combination with antifungal drugs.

Journal: PloS one 20120101

Title: Antiosteoporotic activity of phytoestrogen-rich fraction separated from ethanol extract of aerial parts of Cissus quadrangularis in ovariectomized rats.

Journal: Indian journal of pharmacology 20120101

Title: Comparative activities of the S-enantiomer and racemic forms of equol on bone fragility in ovariectomized mice.

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: Experimentally induced mastitis and metritis modulate soy bean derived isoflavone biotransformation in diary cows.

Journal: Theriogenology 20111201

Title: Suppression of dendritic cells' maturation and functions by daidzein, a phytoestrogen.

Journal: Toxicology and applied pharmacology 20111201

Title: Antioxidant effect of a phytoestrogen equol on cultured muscle cells of embryonic broilers.

Journal: In vitro cellular & developmental biology. Animal 20111201

Title: Dietary isoflavone absorption, excretion, and metabolism in captive cheetahs (Acinonyx jubatus).

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20111201

Title: The effect of carrot juice, β-carotene supplementation on lymphocyte DNA damage, erythrocyte antioxidant enzymes and plasma lipid profiles in Korean smoker.

Journal: Nutrition research and practice 20111201

Title: Impact of 4-methylbenzylidene camphor, daidzein, and estrogen on intact and osteotomized bone in osteopenic rats.

Journal: The Journal of endocrinology 20111101

Title: [Equol-producing phenotype and in relation to serum sex hormones among healthy adults in Beijing].

Journal: Wei sheng yan jiu = Journal of hygiene research 20111101

Title: Resistant starch promotes equol production and inhibits tibial bone loss in ovariectomized mice treated with daidzein.

Journal: Metabolism: clinical and experimental 20111001

Title: Association between dietary phyto-oestrogens and bone density in men and postmenopausal women.

Journal: The British journal of nutrition 20111001

Title: NTP-CERHR expert panel report on the developmental toxicity of soy infant formula.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20111001

Title: Soy isoflavones increase quinone reductase in hepa-1c1c7 cells via estrogen receptor beta and nuclear factor erythroid 2-related factor 2 binding to the antioxidant response element.

Journal: The Journal of nutritional biochemistry 20110901

Title: Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk.

Journal: International journal of food sciences and nutrition 20110901

Title: Soy isoflavones augment the effect of TRAIL-mediated apoptotic death in prostate cancer cells.

Journal: Oncology reports 20110901

Title: Anticancer mechanism of equol in 7,12-dimethylbenz(a)anthracene-treated animals.

Journal: International journal of oncology 20110901

Title: Effects of S-equol and natural S-equol supplement (SE5-OH) on the growth of MCF-7 in vitro and as tumors implanted into ovariectomized athymic mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901

Title: Occurrence and mass balance of isoflavones on an experimental grassland field.

Journal: Environmental science & technology 20110815

Title: Emerging evidence of the health benefits of S-equol, an estrogen receptor β agonist.

Journal: Nutrition reviews 20110801

Title: [Influence of predominant aerobic bacteria isolated from different healthy animals on daidzein biotransforming capacity by co-culture with different daidzein biotransforming bacteria].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20110801

Title: S-equol and the fermented soy product SE5-OH containing S-equol similarly decrease ovariectomy-induced increase in rat tail skin temperature in an animal model of hot flushes.

Journal: Menopause (New York, N.Y.) 20110701

Title: Impact of perinatal exposure to equol enantiomers on reproductive development in rodents.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20110701

Title: The role of soy isoflavones in menopausal health: report of The North American Menopause Society/Wulf H. Utian Translational Science Symposium in Chicago, IL (October 2010).

Journal: Menopause (New York, N.Y.) 20110701

Title: Isolation of estrogen-degrading bacteria from an activated sludge bioreactor treating swine waste, including a strain that converts estrone to β-estradiol.

Journal: Canadian journal of microbiology 20110701

Title: [Anti-invasion effects of R- and S-enantiomers of equol on prostate cancer PC3, DU145 cells].

Journal: Wei sheng yan jiu = Journal of hygiene research 20110701

Title: O-desmethylangolensin: the importance of equol's lesser known cousin to human health.

Journal: Advances in nutrition (Bethesda, Md.) 20110701

Title: [Effect of equol on breast tumors induced by 7, 12-dimethylbenz (α) anthracene in ovariectominzed rats].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20110618

Title: Companion animals symposium: humanized animal models of the microbiome.

Journal: Journal of animal science 20110501

Title: Natural S-equol decreases bone resorption in postmenopausal, non-equol-producing Japanese women: a pilot randomized, placebo-controlled trial.

Journal: Menopause (New York, N.Y.) 20110501

Title: Lactobacillus rhamnosus JCM 2771: impact on metabolism of isoflavonoids in the fecal flora from a male equol producer.

Journal: Current microbiology 20110501

Title: Impact of dietary soy isoflavones in pregnancy on fetal programming of endothelial function in offspring.

Journal: Microcirculation (New York, N.Y. : 1994) 20110501

Title: How can research on plants contribute to promoting human health?

Journal: The Plant cell 20110501

Title: Development of chiral liquid chromatography-tandem mass spectrometry isotope dilution methods for the determination of unconjugated and total S-equol in human plasma and urine.

Journal: Journal of pharmaceutical and biomedical analysis 20110428

Title: Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30.

Journal: Hypertension (Dallas, Tex. : 1979) 20110401

Title: Critical evaluation of key evidence on the human health hazards of exposure to bisphenol A.

Journal: Critical reviews in toxicology 20110401

Title: Hippocampal responsiveness to 17β-estradiol and equol after long-term ovariectomy: implication for a therapeutic window of opportunity.

Journal: Brain research 20110316

Title: Higher bioavailability of isoflavones after a single ingestion of aglycone-rich fermented soybeans compared with glucoside-rich non-fermented soybeans in Japanese postmenopausal women.

Journal: Journal of the science of food and agriculture 20110315

Title: Urinary isoflavone phytoestrogens in German children and adolescents--a longitudinal examination in the DONALD cohort.

Journal: Molecular nutrition & food research 20110301

Title: Plasma isoflavones and the risk of lung cancer in women: a nested case-control study in Japan.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110301

Title: The mind-body-microbial continuum.

Journal: Dialogues in clinical neuroscience 20110301

Title: Quantification of five isoflavones and coumestrol in various solid agroenvironmental matrices using ¹³c₃-labeled internal standards.

Journal: Journal of agricultural and food chemistry 20110209

Title: Is equol production beneficial to health?

Journal: The Proceedings of the Nutrition Society 20110201

Title: Single-dose and steady-state pharmacokinetic studies of S-equol, a potent nonhormonal, estrogen receptor β-agonist being developed for the treatment of menopausal symptoms.

Journal: Menopause (New York, N.Y.) 20110201

Title: The effect of equol injection in ovo on posthatch growth, meat quality and antioxidation in broilers.

Journal: Animal : an international journal of animal bioscience 20110201

Title: Addition of fructooligosaccharides and dried plum to soy-based diets reverses bone loss in the ovariectomized rat.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Transcriptional activity of estrogen-related receptor γ (ERRγ) is stimulated by the phytoestrogen equol.

Journal: The Journal of steroid biochemistry and molecular biology 20110101

Title: Development of bioluminescent enzyme immunoassay for s-equol using firefly luciferase and its application to the assessment of equol-producer status.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Equol an isoflavonoid: potential for improved prostate health, in vitro and in vivo evidence.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Soy isoflavone equol perpetuates dextran sulfate sodium-induced acute colitis in mice.

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Neuromodulation by soy diets or equol: anti-depressive & anti-obesity-like influences, age- & hormone-dependent effects.

Journal: BMC neuroscience 20110101

Title: [Equol induced apoptosis of human breast cancer MDA-MB-231 cell by inhibiting the expression of nuclear factor-kappaB].

Journal: Wei sheng yan jiu = Journal of hygiene research 20110101

Title: Chemopreventive potential of synergy1 and soybean in reducing azoxymethane-induced aberrant crypt foci in fisher 344 male rats.

Journal: Journal of nutrition and metabolism 20110101

Title: Phytoestrogen biological actions on Mammalian reproductive system and cancer growth.

Journal: Scientia pharmaceutica 20110101

Title: Chemoprevention of prostate cancer with nutrients and supplements.

Journal: Cancer management and research 20110101

Title: Distribution of isoflavones in samples of serum, liver and mammary glands of rats or pigs fed dietary isoflavones.

Journal: Annals of nutrition & metabolism 20110101

Title: Effects of vitamin d plus calcium supplements on pharmacokinetics of isoflavones in thai postmenopausal women.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Screening for estrogenic and antiestrogenic activities of plants growing in Egypt and Thailand.

Journal: Pharmacognosy research 20110101

Title: Evaluation of CYP450 inhibitory effects and steady-state pharmacokinetics of genistein in combination with cholecalciferol and citrated zinc bisglycinate in postmenopausal women.

Journal: International journal of women's health 20110101

Title: Bacteria, food, and cancer.

Journal: F1000 biology reports 20110101

Title: Does Glycine max leaves or Garcinia Cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: a randomized control trial.

Journal: Nutrition journal 20110101

Title: Combinational Effects of Prebiotics and Soybean against Azoxymethane-Induced Colon Cancer In Vivo.

Journal: Journal of nutrition and metabolism 20110101

Title: Phytoestrogens in postmenopausal indications: A theoretical perspective.

Journal: Pharmacognosy reviews 20110101

Title: Intestinal absorbability of three Radix Puerariae isoflavones including daidzein, daidzin and puerarin.

Journal: Chinese medicine 20110101

Title: Quantitative and qualitative analyses of the cell death process in Candida albicans treated by antifungal agents.

Journal: PloS one 20110101

Title: Chemoprevention of prostate cancer: Natural compounds, antiandrogens, and antioxidants - In vivo evidence.

Journal: Journal of carcinogenesis 20110101

Title: Identification of two novel reductases involved in equol biosynthesis in Lactococcus strain 20-92.

Journal: Journal of molecular microbiology and biotechnology 20110101

Title: Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants.

Journal: Frontiers in genetics 20110101

Title: Natural products and body weight control.

Journal: North American journal of medical sciences 20110101

Title: Modulation of monoamine neurotransmitters in fighting fish Betta splendens exposed to waterborne phytoestrogens.

Journal: Fish physiology and biochemistry 20101201

Title: Genotoxicity assessment of S-equol in bacterial mutation, chromosomal aberration, and rodent bone marrow micronucleus tests.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101201

Title: Urinary phytoestrogens and risk of prostate cancer in Jamaican men.

Journal: Cancer causes & control : CCC 20101201

Title: Rapid signaling actions of environmental estrogens in developing granule cell neurons are mediated by estrogen receptor ß.

Journal: Endocrinology 20101201

Title: Plasma testosterone and sex hormone-binding globulin concentrations and the risk of prostate cancer among Japanese men: a nested case-control study.

Journal: Cancer science 20101201

Title: Mammary gland differentiation by early life exposure to enantiomers of the soy isoflavone metabolite equol.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101

Title: Effects of a high dose, aglycone-rich soy extract on prostate-specific antigen and serum isoflavone concentrations in men with localized prostate cancer.

Journal: Nutrition and cancer 20101101

Title: [Research development on relation between equol and soy foods health effect].

Journal: Wei sheng yan jiu = Journal of hygiene research 20101101

Title: [Advances on the study of equol metabolism in human].

Journal: Wei sheng yan jiu = Journal of hygiene research 20101101

Title: Early exposure to soy isoflavones and effects on reproductive health: a review of human and animal studies.

Journal: Nutrients 20101101

Title: Synthesis of isoflavone aglycones and equol in soy milks fermented by food-related lactic acid bacteria and their effect on human intestinal Caco-2 cells.

Journal: Journal of agricultural and food chemistry 20101013

Title: Topical isoflavonoids reduce experimental cutaneous inflammation in mice.

Journal: Immunology and cell biology 20101001

Title: Individual and combined soy isoflavones exert differential effects on metastatic cancer progression.

Journal: Clinical & experimental metastasis 20101001

Title: Profiles of phytoestrogens in human urine from several Asian countries.

Journal: Journal of agricultural and food chemistry 20100908

Title: Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARgamma transcriptional activity.

Journal: The Journal of nutritional biochemistry 20100901

Title: Overnight urinary excretion of isoflavones as an indicator for dietary isoflavone intake in Korean girls of pubertal age.

Journal: The British journal of nutrition 20100901

Title: Dietary genistein and equol (4', 7 isoflavandiol) reduce oxidative stress and protect rats against focal cerebral ischemia.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100901

Title: Slackia equolifaciens sp. nov., a human intestinal bacterium capable of producing equol.

Journal: International journal of systematic and evolutionary microbiology 20100801

Title: Assessment of a robust model protocol with accelerated throughput for a human recombinant full length estrogen receptor-alpha binding assay: protocol optimization and intralaboratory assay performance as initial steps towards validation.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20100801

Title: Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A.

Journal: Environmental health perspectives 20100801

Title: The role of soy in vegetarian diets.

Journal: Nutrients 20100801

Title: Conversion of (3S,4R)-tetrahydrodaidzein to (3S)-equol by THD reductase: proposed mechanism involving a radical intermediate.

Journal: Biochemistry 20100706

Title: Enterorhabdus caecimuris sp. nov., a member of the family Coriobacteriaceae isolated from a mouse model of spontaneous colitis, and emended description of the genus Enterorhabdus Clavel et al. 2009.

Journal: International journal of systematic and evolutionary microbiology 20100701

Title: Daidzein-metabolising phenotypes in relation to serum lipids and uric acid in adults in Guangzhou, China.

Journal: The British journal of nutrition 20100701

Title: Effect of daidzein on anxiety, social behavior and spatial learning in male Balb/cJ mice.

Journal: Pharmacology, biochemistry, and behavior 20100701

Title: Effects of genistein and equol on human and rat testicular 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities.

Journal: Asian journal of andrology 20100701

Title: Arsenic metabolism by human gut microbiota upon in vitro digestion of contaminated soils.

Journal: Environmental health perspectives 20100701

Title: Urine accurately reflects circulating isoflavonoids and ascertains compliance during soy intervention.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100701

Title: Effects of isoflavones equol and genistein on bone quality in a rat osteopenia model.

Journal: Phytotherapy research : PTR 20100601

Title: Microbial equol production attenuates colonic methanogenesis and sulphidogenesis in vitro.

Journal: Anaerobe 20100601

Title: Activation of transgenic estrogen receptor-beta by selected phytoestrogens in a stably transduced rat serotonergic cell line.

Journal: The Journal of steroid biochemistry and molecular biology 20100601

Title: Suppression of colonic aberrant crypt foci by soy isoflavones is dose-independent in dimethylhydrazine-treated rats.

Journal: Journal of medicinal food 20100601

Title: Delayed activation of extracellular-signal-regulated kinase 1/2 is involved in genistein- and equol-induced cell proliferation and estrogen-receptor-alpha-mediated transcription in MCF-7 breast cancer cells.

Journal: The Journal of nutritional biochemistry 20100501

Title: Evaluation of bone quality and quantity in osteoporotic mice--the effects of genistein and equol.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100501

Title: The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer.

Journal: Carcinogenesis 20100501

Title: Diethylstilbestrol and other nonsteroidal estrogens: novel class of store-operated calcium channel modulators.

Journal: Journal of cardiovascular pharmacology 20100501

Title: Effect of diet on fecal and urinary estrogenic activity.

Journal: Journal of dairy science 20100501

Title: Isoflavones from phytoestrogens and gastric cancer risk: a nested case-control study within the Korean Multicenter Cancer Cohort.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100501

Title: Development of a high-throughput LC/APCI-MS method for the determination of thirteen phytoestrogens including gut microbial metabolites in human urine and serum.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415

Title: Combination of genistin and fructooligosaccharides prevents bone loss in ovarian hormone deficiency.

Journal: Journal of medicinal food 20100401

Title: Isolation and characterization of the equol-producing bacterium Slackia sp. strain NATTS.

Journal: Archives of microbiology 20100401

Title: Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation.

Journal: International journal of dermatology 20100301

Title: Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR.

Journal: Nutrients 20100301

Title: Comparative effects of R- and S-equol and implication of transactivation functions (AF-1 and AF-2) in estrogen receptor-induced transcriptional activity.

Journal: Nutrients 20100301

Title: Changes in the histomorphometric and biomechanical properties of the proximal femur of ovariectomized rat after treatment with the phytoestrogens genistein and equol.

Journal: Planta medica 20100201

Title: Comparison of urodynamic effects of phytoestrogens equol, puerarin and genistein with these of estradiol 17beta in ovariectomized rats.

Journal: Experimental gerontology 20100201

Title: Isolation and identification of urinary metabolites of kakkalide in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201

Title: Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database.

Journal: The American journal of clinical nutrition 20100201

Title: Isoflavone effect on gene expression profile and biomarkers of inflammation.

Journal: Journal of pharmaceutical and biomedical analysis 20100120

Title: The soy isoflavone equol enhances antigen-specific IgE production in ovalbumin-immunized BALB/c mice.

Journal: Journal of nutritional science and vitaminology 20100101

Title: [Prevalence of equol producer phenotype and its relations to lifestyle factors and dietary intakes among lifestyle factors and dietary intakes among healthy Chinese adults in Beijing].

Journal: Wei sheng yan jiu = Journal of hygiene research 20100101

Title: Bioactivity of isoflavones: assessment through a theoretical model as a way to obtain a 'Theoretical Efficacy Related to Estradiol (TERE)'.

Journal: International journal of molecular sciences 20100101

Title: Bioavailability of the polyphenols: status and controversies.

Journal: International journal of molecular sciences 20100101

Title: Impact of dietary polyphenols on carbohydrate metabolism.

Journal: International journal of molecular sciences 20100101

Title: Effects of isoflavones on breast density in pre- and post-menopausal women: a systematic review and meta-analysis of randomized controlled trials.

Journal: Human reproduction update 20100101

Title: Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells.

Journal: BMC biochemistry 20100101

Title: The influence of bovine milk high or low in isoflavones on hepatic gene expression in mice.

Journal: Journal of toxicology 20100101

Title: Prevalence of the equol-producer phenotype and its relationship with dietary isoflavone and serum lipids in healthy Chinese adults.

Journal: Journal of epidemiology 20100101

Title: A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity.

Journal: Journal of osteoporosis 20100101

Title: Organization of GC/MS and LC/MS metabolomics data into chemical libraries.

Journal: Journal of cheminformatics 20100101

Title: Does consuming isoflavones reduce or increase breast cancer risk?

Journal: Genome medicine 20100101

Title: Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial.

Journal: Breast cancer : basic and clinical research 20100101

Title: Phytoestrogens and mycotoxins in Iowa streams: an examination of underinvestigated compounds in agricultural basins.

Journal: Journal of environmental quality 20100101

Title: Can rye intake decrease risk of human breast cancer?

Journal: Food & nutrition research 20100101

Title: Isoflavones and PPAR Signaling: A Critical Target in Cardiovascular, Metastatic, and Metabolic Disease.

Journal: PPAR research 20100101

Title: Alterations in bone turnover by isoflavone aglycone supplementation in relation to estrogen receptor α polymorphism.

Journal: Molecular medicine reports 20100101

Title: GC-MS determined distribution of urinary equol producers as affected by age, gender, and repeated ingestions of soymilk.

Journal: Journal of food science 20100101

Title: Phytoconstituents as photoprotective novel cosmetic formulations.

Journal: Pharmacognosy reviews 20100101

Title: Epidemiologic studies of isoflavones & mammographic density.

Journal: Nutrients 20100101

Title: The role of diet in the metabolism of daidzein by human faecal microbiota sampled from Italian volunteers.

Journal: The Journal of nutritional biochemistry 20091201

Title: Equol in milk of dairy cows is derived from forage legumes such as red clover.

Journal: The British journal of nutrition 20091201

Title: Dietary cholesterol lowers plasma and cecal equol concentrations in mice.

Journal: Nutrition research (New York, N.Y.) 20091201

Title: Oral exposure to genistin, the glycosylated form of genistein, during neonatal life adversely affects the female reproductive system.

Journal: Environmental health perspectives 20091201

Title: Isoflavonoids - an overview of their biological activities and potential health benefits.

Journal: Interdisciplinary toxicology 20091201

Title: Lactobacillus collinoides JCM1123(T): effects on mouse plasma cholesterol and isoflavonoids in the caecum.

Journal: Antonie van Leeuwenhoek 20091101

Title: Gastrointestinal microflora, food components and colon cancer prevention.

Journal: The Journal of nutritional biochemistry 20091001

Title: Urinary phytoestrogen excretion and postmenopausal breast cancer risk: the multiethnic cohort study.

Journal: Cancer prevention research (Philadelphia, Pa.) 20091001

Title: [Nutrition and bone health. Isoflavones in bone health].

Journal: Clinical calcium 20091001

Title: Marked individual variation in isoflavone metabolism after a soy challenge can modulate the skeletal effect of isoflavones in premenopausal women.

Journal: Journal of Korean medical science 20091001

Title: Transport and metabolism of equol by Caco-2 human intestinal cells.

Journal: Journal of agricultural and food chemistry 20090923

Title: Isoflavones are safe compounds for therapeutical applications - evaluation of in vitro data.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090901

Title: Isoflavone supplements stimulated the production of serum equol and decreased the serum dihydrotestosterone levels in healthy male volunteers.

Journal: Prostate cancer and prostatic diseases 20090901

Title: The improvement of hypertension by probiotics: effects on cholesterol, diabetes, renin, and phytoestrogens.

Journal: International journal of molecular sciences 20090901

Title: Occurrence and origin of estrogenic isoflavones in Swiss river waters.

Journal: Environmental science & technology 20090815

Title: Gas chromatographic-mass spectrometric fragmentation study of phytoestrogens as their trimethylsilyl derivatives: identification in soy milk and wastewater samples.

Journal: Journal of chromatography. A 20090807

Title: Daidzein-metabolizing phenotypes in relation to mammographic breast density among premenopausal women in the United States.

Journal: Breast cancer research and treatment 20090801

Title: Chronic equol administration attenuates the antioxidant defense system and causes apoptosis in the mouse brain.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801

Title: Phyto-oestrogens in herbage and milk from cows grazing white clover, red clover, lucerne or chicory-rich pastures.

Journal: Animal : an international journal of animal bioscience 20090801

Title: Urinary phytoestrogen excretion and prostate cancer risk: a nested case-control study in the Multiethnic Cohort.

Journal: British journal of cancer 20090707

Title: Estrogenic activity of bovine milk high or low in equol using immature mouse uterotrophic responses and an estrogen receptor transactivation assay.

Journal: Cancer epidemiology 20090701

Title: Plasma phyto-oestrogens and prostate cancer in the European Prospective Investigation into Cancer and Nutrition.

Journal: British journal of cancer 20090602

Title: Association between estrogen receptor alpha polymorphisms and equol production, and its relation to bone mass.

Journal: International journal of molecular medicine 20090601

Title: Biotransformation of daidzein to equol by crude enzyme from Asaccharobacter celatus AHU1763 required an anaerobic environment.

Journal: Bioscience, biotechnology, and biochemistry 20090601

Title: Effects of isoflavones on the skin of postmenopausal women: a pilot study.

Journal: Clinics (Sao Paulo, Brazil) 20090601

Title: Effects of equol on oxidized low-density lipoprotein-induced apoptosis in endothelial cells.

Journal: Journal of atherosclerosis and thrombosis 20090601

Title: Prostatic soy isoflavone concentrations exceed serum levels after dietary supplementation.

Journal: The Prostate 20090515

Title: Comparison of flavonoids and isoflavonoids as antioxidants.

Journal: Journal of agricultural and food chemistry 20090513

Title: Respective contribution exerted by AF-1 and AF-2 transactivation functions in estrogen receptor alpha induced transcriptional activity by isoflavones and equol: consequence on breast cancer cell proliferation.

Journal: Molecular nutrition & food research 20090501

Title: Ileal and faecal digestibility of daidzein and genistein and plasma bioavailability of these isoflavones and their bioactive metabolites in the ovariectomised rat.

Journal: Molecular nutrition & food research 20090501

Title: Hepatoprotective effects of daidzein against 7,12-dimetylbenz[a]anthracene-induced oxidative stress in mice.

Journal: International journal of molecular medicine 20090501

Title: A comparative analysis of genistein and daidzein in affecting lipid metabolism in rat liver.

Journal: Journal of clinical biochemistry and nutrition 20090501

Title: Effect of glycosidation of isoflavones on their bioavailability and pharmacokinetics in aged male rats.

Journal: Molecular nutrition & food research 20090501

Title: Impact of neonatal exposure to the ERalpha agonist PPT, bisphenol-A or phytoestrogens on hypothalamic kisspeptin fiber density in male and female rats.

Journal: Neurotoxicology 20090501

Title: Targeting the redox sensitive Nrf2-Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones.

Journal: Current opinion in pharmacology 20090401

Title: Equol but not genistein improves early metaphyseal fracture healing in osteoporotic rats.

Journal: Planta medica 20090401

Title: Effect of forage on the content of phyto-oestrogens in bovine milk.

Journal: Animal : an international journal of animal bioscience 20090401

Title: Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets.

Journal: Thrombosis research 20090301

Title: Evaluation of equol function on anti- or prooxidant status in vivo.

Journal: Journal of food science 20090301

Title: Enhancement of the activity of phenoxodiol by cisplatin in prostate cancer cells.

Journal: British journal of cancer 20090224

Title: Dietary combination of soy with a probiotic or prebiotic food significantly reduces total and LDL cholesterol in mildly hypercholesterolaemic subjects.

Journal: European journal of clinical nutrition 20090201

Title: Isoflavones in urine, saliva, and blood of infants: data from a pilot study on the estrogenic activity of soy formula.

Journal: Journal of exposure science & environmental epidemiology 20090201

Title: A select combination of clinically relevant phytoestrogens enhances estrogen receptor beta-binding selectivity and neuroprotective activities in vitro and in vivo.

Journal: Endocrinology 20090201

Title: Gastrointestinal absorption and metabolism of soy isoflavonoids in ileal-canulated swine.

Journal: Molecular nutrition & food research 20090201

Title: Soy, isoflavones, and prostate cancer.

Journal: Molecular nutrition & food research 20090201

Title: Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats.

Journal: Hormones and behavior 20090201

Title: Soy phytoestrogens are neuroprotective against stroke-like injury in vitro.

Journal: Neuroscience 20090123

Title: Equol induces apoptosis through cytochrome c-mediated caspases cascade in human breast cancer MDA-MB-453 cells.

Journal: Chemico-biological interactions 20090115

Title: Modulation of neurotoxicant-induced increases in intracellular calcium by phytoestrogens differ for amyloid beta peptide (Abeta) and 1-methyl-4-phenyl-pyridine (MPP(+)).

Journal: Journal of applied toxicology : JAT 20090101

Title: A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women.

Journal: Age and ageing 20090101

Title: New equol supplement for relieving menopausal symptoms: randomized, placebo-controlled trial of Japanese women.

Journal: Menopause (New York, N.Y.) 20090101

Title: [Effect of equol of a isoflavone metabolite on menopausal symptoms].

Journal: Wei sheng yan jiu = Journal of hygiene research 20090101

Title: Resistance training with soy vs whey protein supplements in hyperlipidemic males.

Journal: Journal of the International Society of Sports Nutrition 20090101

Title: Effects of soy protein and isoflavones on circulating hormone concentrations in pre- and post-menopausal women: a systematic review and meta-analysis.

Journal: Human reproduction update 20090101

Title: The phytoestrogen genistein affects zebrafish development through two different pathways.

Journal: PloS one 20090101

Title: Modulation of CXCR4, CXCL12, and Tumor Cell Invasion Potential In Vitro by Phytochemicals.

Journal: Journal of oncology 20090101

Title: Inflammatory markers in a 2-year soy intervention among premenopausal women.

Journal: Journal of inflammation (London, England) 20090101

Title: Soybean isoflavones in bone health.

Journal: Forum of nutrition 20090101

Title: Validity and reproducibility of a self-administered semi-quantitative food-frequency questionnaire for estimating usual daily fat, fibre, alcohol, caffeine and theobromine intakes among Belgian post-menopausal women.

Journal: International journal of environmental research and public health 20090101

Title: Quasi-MSn identification of flavanone 7-glycoside isomers in Da Chengqi Tang by high performance liquid chromatography-tandem mass spectrometry.

Journal: Chinese medicine 20090101

Title: Constitutional flavonoids derived from Epimedium dose-dependently reduce incidence of steroid-associated osteonecrosis not via direct action by themselves on potential cellular targets.

Journal: PloS one 20090101

Title: Fetal programming of adult glucose homeostasis in mice.

Journal: PloS one 20090101

Title: Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient.

Journal: Journal of toxicology 20090101

Title: The response of creatine kinase specific activity in rat pituitary to estrogenic compounds and vitamin d less-calcemic analogs.

Journal: International journal of cell biology 20090101

Title: Variation in chemotactic preferences of Aphanomyces cochlioides zoospores to flavonoids.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101

Title: Plasma isoflavones and subsequent risk of prostate cancer in a nested case-control study: the Japan Public Health Center.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081220

Title: Consumption of isoflavone-rich soy protein does not alter homocysteine or markers of inflammation in postmenopausal women.

Journal: European journal of clinical nutrition 20081201

Title: Coronary vasomotor and blood flow responses to isoflavone-intact soya protein in subjects with coronary heart disease or risk factors for coronary heart disease.

Journal: Clinical science (London, England : 1979) 20081201

Title: Daidzein-metabolizing phenotypes in relation to serum hormones and sex hormone binding globulin, and urinary estrogen metabolites in premenopausal women in the United States.

Journal: Cancer causes & control : CCC 20081201

Title: Phytoestrogens and phytoestrogen metabolites differentially modulate immune parameters in human leukocytes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201

Title: Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes.

Journal: The Journal of steroid biochemistry and molecular biology 20081201

Title: Understanding the cardiovascular actions of soy isoflavones: potential novel targets for antihypertensive drug development.

Journal: Cardiovascular & hematological disorders drug targets 20081201

Title: Food matrix and isoflavones bioavailability in early post menopausal women: a European clinical study.

Journal: Clinical interventions in aging 20081201

Title: Phytoestrogen content of foods of animal origin: dairy products, eggs, meat, fish, and seafood.

Journal: Journal of agricultural and food chemistry 20081112

Title: Disrupted female reproductive physiology following neonatal exposure to phytoestrogens or estrogen specific ligands is associated with decreased GnRH activation and kisspeptin fiber density in the hypothalamus.

Journal: Neurotoxicology 20081101

Title: Receptor binding and transactivation activities of red clover isoflavones and their metabolites.

Journal: The Journal of steroid biochemistry and molecular biology 20081101

Title: Experimental benefits of sex hormones on vascular function and the outcome of hormone therapy in cardiovascular disease.

Journal: Current cardiology reviews 20081101

Title: Antioxidant effects of equol on bovine aortic endothelial cells.

Journal: Biochemical and biophysical research communications 20081024

Title: Concentrations of isoflavones and their metabolites in the blood of pregnant and non-pregnant heifers fed soy bean.

Journal: The Journal of reproduction and development 20081001

Title: Impact of soy supplementation on sex steroids and vascular inflammation markers in postmenopausal women using tibolone: role of equol production capability.

Journal: Climacteric : the journal of the International Menopause Society 20081001

Title: Isolation and characterization of a novel equol-producing bacterium from human feces.

Journal: Bioscience, biotechnology, and biochemistry 20081001

Title: Soy protein containing isoflavones and mammographic density in a randomized controlled trial in postmenopausal women.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081001

Title: Lack of prospective associations between plasma and urinary phytoestrogens and risk of prostate or colorectal cancer in the European Prospective into Cancer-Norfolk study.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081001

Title: Guar gum and similar soluble fibers in the regulation of cholesterol metabolism: current understandings and future research priorities.

Journal: Vascular health and risk management 20081001

Title: Effects of extracted soy isoflavones alone on blood total and LDL cholesterol: Meta-analysis of randomized controlled trials.

Journal: Therapeutics and clinical risk management 20081001

Title: Cancer is a preventable disease that requires major lifestyle changes.

Journal: Pharmaceutical research 20080901

Title: Effect of isoflavones on cardiovascular health: low but not out either.

Journal: Journal of clinical biochemistry and nutrition 20080901

Title: Tissue distribution of isoflavones in ewes after consumption of red clover silage.

Journal: Archives of biochemistry and biophysics 20080815

Title: Urinary isoflavonoid excretion is similar after consuming soya milk and miso soup in Japanese-American women.

Journal: The British journal of nutrition 20080801

Title: Acute and subchronic toxicity and genotoxicity of SE5-OH, an equol-rich product produced by Lactococcus garvieae.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080801

Title: Comparative activities of daidzein metabolites, equol and O-desmethylangolensin, on bone mineral density and lipid metabolism in ovariectomized mice and in osteoclast cell cultures.

Journal: European journal of nutrition 20080801

Title: Biotransformation of C-glucosylisoflavone puerarin to estrogenic (3S)-equol in co-culture of two human intestinal bacteria.

Journal: Biological & pharmaceutical bulletin 20080801

Title: Effect of intestinal production of equol on menopausal symptoms in women treated with soy isoflavones.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080701

Title: Effects of clover-grass silages and concentrate supplementation on the content of phytoestrogens in dairy cow milk.

Journal: Journal of dairy science 20080701

Title: Effect of sulphation on the oestrogen agonist activity of the phytoestrogens genistein and daidzein in MCF-7 human breast cancer cells.

Journal: The Journal of endocrinology 20080601

Title: Equol production capability is associated with favorable vascular function in postmenopausal women using tibolone; no effect with soy supplementation.

Journal: Atherosclerosis 20080501

Title: Isolation and identification of equol-producing bacterial strains from cultures of pig faeces.

Journal: FEMS microbiology letters 20080501

Title: Development of techniques for the analysis of isoflavones in soy foods and nutraceuticals.

Journal: Current opinion in clinical nutrition and metabolic care 20080501

Title: Adlercreutzia equolifaciens gen. nov., sp. nov., an equol-producing bacterium isolated from human faeces, and emended description of the genus Eggerthella.

Journal: International journal of systematic and evolutionary microbiology 20080501

Title: Genome analysis of food grade lactic Acid-producing bacteria: from basics to applications.

Journal: Current genomics 20080501

Title: Low activities of intestinal lactase suppress the early phase absorption of soy isoflavones in Japanese adults.

Journal: Clinical nutrition (Edinburgh, Scotland) 20080401

Title: Neonatal exposure to endocrine active compounds or an ERbeta agonist increases adult anxiety and aggression in gonadally intact male rats.

Journal: Hormones and behavior 20080401

Title: Topical isoflavones provide effective photoprotection to skin.

Journal: Photodermatology, photoimmunology & photomedicine 20080401

Title: Phytoestrogens and breast cancer prevention: possible mechanisms of action.

Journal: Environmental health perspectives 20080401

Title: Meeting report: batch-to-batch variability in estrogenic activity in commercial animal diets--importance and approaches for laboratory animal research.

Journal: Environmental health perspectives 20080301

Title: Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women.

Journal: British journal of cancer 20080212

Title: Inhibition by soya isoflavones of human polymorphonuclear leukocyte function: possible relevance for the beneficial effects of soya intake.

Journal: The British journal of nutrition 20080201

Title: Screening of synthetic and plant-derived compounds for (anti)estrogenic and (anti)androgenic activities.

Journal: Analytical and bioanalytical chemistry 20080201

Title: Dietary soy isoflavone-aglycone lowers food intake in female rats with and without ovariectomy.

Journal: Obesity (Silver Spring, Md.) 20080201

Title: Isoflavones regulate secretion of leukemia inhibitory factor and transforming growth factor {beta} and expression of glycodelin in human endometrial epithelial cells.

Journal: The Journal of endocrinology 20080201

Title: Epidemiology of soy exposures and breast cancer risk.

Journal: British journal of cancer 20080115

Title: Effects of dietary equol administration on the mammary gland in ovariectomized Sprague-Dawley rats.

Journal: Menopause (New York, N.Y.) 20080101

Title: Determination of urinary phytoestrogens by HPLC-MS/MS: a comparison of atmospheric pressure chemical ionization (APCI) and electrospray ionization (ESI).

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080101

Title: Estrogenic activities of isoflavones and flavones and their structure-activity relationships.

Journal: Planta medica 20080101

Title: Age-stratified serum levels of isoflavones and proportion of equol producers in Japanese and Korean healthy men.

Journal: Prostate cancer and prostatic diseases 20080101

Title: Equol status modifies the association of soy intake and mammographic density in a sample of postmenopausal women.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101

Title: Clone-specific expression, transcriptional regulation, and action of interleukin-6 in human colon carcinoma cells.

Journal: BMC cancer 20080101

Title: Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study.

Journal: Breast cancer research : BCR 20080101

Title: Oral antibiotics decrease urinary isoflavonoid excretion in children after soy consumption.

Journal: Nutrition and cancer 20080101

Title: Dietary and lifestyle correlates of urinary excretion status of equol in Japanese women.

Journal: Nutrition and cancer 20080101

Title: Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trial.

Journal: Menopause (New York, N.Y.) 20080101

Title: Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy.

Journal: BMC cancer 20080101

Title: Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary.

Journal: Nutrition journal 20080101

Title: Red clover extract: a putative source for simultaneous treatment of menopausal disorders and the metabolic syndrome.

Journal: Menopause (New York, N.Y.) 20080101

Title: Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice.

Journal: BMC physiology 20080101

Title: Baseline urinary phytoestrogen levels and the natural history of untreated, localised prostate cancer in a British population.

Journal: The International journal of biological markers 20080101

Title: Timing of supplementation of selenium and isoflavones determines prostate cancer risk factor reduction in rats.

Journal: Nutrition & metabolism 20080101

Title: Dose-response assessment of the anti-cancer efficacy of soy isoflavones in dimethylhydrazine-treated rats fed 6% fructooligosaccharide.

Journal: Nutrition research and practice 20080101

Title: Equol induced apoptosis via cell cycle arrest in human breast cancer MDA-MB-453 but not MCF-7 cells.

Journal: Molecular medicine reports 20080101

Title: Individual differences in equol production capability modulate blood pressure in tibolone-treated postmenopausal women: lack of effect of soy supplementation.

Journal: Climacteric : the journal of the International Menopause Society 20071201

Title: Variations in phytoestrogen content between different mill dates of the same diet produces significant differences in the time of vaginal opening in CD-1 mice and F344 rats but not in CD Sprague-Dawley rats.

Journal: Environmental health perspectives 20071201

Title: Effects of chronic genistein treatment in mammary gland, uterus, and vagina.

Journal: Environmental health perspectives 20071201

Title: Effects of dietary equol administration on ovariectomy induced bone loss in Sprague-Dawley rats.

Journal: Maturitas 20071120

Title: Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway.

Journal: The Journal of biological chemistry 20071109

Title: WHI and WHIMS follow-up and human studies of soy isoflavones on cognition.

Journal: Expert review of neurotherapeutics 20071101

Title: Quantification of six phytoestrogens at the nanogram per liter level in aqueous environmental samples using 13C3-labeled internal standards.

Journal: Journal of agricultural and food chemistry 20071017

Title: Isoflavonoid-based bone-sparing treatments exert a low activity on reproductive organs and on hepatic metabolism of estradiol in ovariectomized rats.

Journal: Toxicology and applied pharmacology 20071015

Title: Increased probiotic yogurt or resistant starch intake does not affect isoflavone bioavailability in subjects consuming a high soy diet.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20071001

Title: Uterotropic effects of dietary equol administration in ovariectomized Sprague-Dawley rats.

Journal: Climacteric : the journal of the International Menopause Society 20071001

Title: A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice.

Journal: Environmental health perspectives 20071001

Title: Role of tyrosine phosphorylation in U46619-induced vasoconstriction of pulmonary vasculature and its modulation by genistein, daidzein, and equol.

Journal: Journal of cardiovascular pharmacology 20071001

Title: Soy and prostate cancer study results mixed.

Journal: Journal of the National Cancer Institute 20070919

Title: Chemical composition and biological activity of a new type of Brazilian propolis: red propolis.

Journal: Journal of ethnopharmacology 20070905

Title: Aza analogues of equol: novel ligands for estrogen receptor beta.

Journal: Bioorganic & medicinal chemistry 20070901

Title: Glycitein activates extracellular signal-regulated kinase via vascular endothelial growth factor receptor signaling in nontumorigenic (RWPE-1) prostate epithelial cells.

Journal: The Journal of nutritional biochemistry 20070801

Title: Phyto-oestrogens and risk of prostate cancer in Scottish men.

Journal: The British journal of nutrition 20070801

Title: Metabolism of isoflavones, lignans and prenylflavonoids by intestinal bacteria: producer phenotyping and relation with intestinal community.

Journal: FEMS microbiology ecology 20070801

Title: High levels of equol in organic skimmed Finnish cow milk.

Journal: Molecular nutrition & food research 20070701

Title: Bioavailability of soy isoflavones in rats Part I: application of accurate methodology for studying the effects of gender and source of isoflavones.

Journal: Molecular nutrition & food research 20070701

Title: Metabolism of dietary soy isoflavones to equol by human intestinal microflora--implications for health.

Journal: Molecular nutrition & food research 20070701

Title: Simultaneous determination of daidzein, equol, genistein and bisphenol A in human urine by a fast and simple method using SPE and GC-MS.

Journal: Molecular nutrition & food research 20070701

Title: Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not.

Journal: The Journal of nutritional biochemistry 20070601

Title: A thermodynamic analysis on adsorption of estrogens in activated sludge process.

Journal: Water research 20070601

Title: Does the effect of soy phytoestrogens on bone in postmenopausal women depend on the equol-producing phenotype?

Journal: Nutrition reviews 20070601

Title: Metabolism of daidzein by fecal bacteria in rats.

Journal: Comparative medicine 20070601

Title: Modulation of soy isoflavones bioavailability and subsequent effects on bone health in ovariectomized rats: the case for equol.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20070501

Title: Variations in plasma phytoestrogen concentrations in European adults.

Journal: The Journal of nutrition 20070501

Title: Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070501

Title: Vasorelaxant and antioxidant activity of the isoflavone metabolite equol in carotid and cerebral arteries.

Journal: Brain research 20070413

Title: Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys.

Journal: Carcinogenesis 20070401

Title: Monoclonal antibody-based time-resolved fluorescence immunoassays for daidzein, genistein, and equol in blood and urine: application to the Isoheart intervention study.

Journal: Clinical chemistry 20070401

Title: Equol inhibits nitric oxide production and inducible nitric oxide synthase gene expression through down-regulating the activation of Akt.

Journal: International immunopharmacology 20070401

Title: Effects of dietary equol on the pituitary of the ovariectomized rats.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070401

Title: Bioavailability and urinary excretion of isoflavones in humans: effects of soy-based supplements formulation and equol production.

Journal: Journal of pharmaceutical and biomedical analysis 20070312

Title: Urinary excretion of equol by postmenopausal women consuming soymilk fermented by probiotic bifidobacteria.

Journal: European journal of clinical nutrition 20070301

Title: Plasma phytoestrogens and subsequent breast cancer risk.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070220

Title: Urinary isoflavonoid excretion and soy consumption in three generations of Japanese women in Hawaii.

Journal: European journal of clinical nutrition 20070201

Title: Production of phytoestrogen S-equol from daidzein in mixed culture of two anaerobic bacteria.

Journal: Archives of microbiology 20070201

Title: Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces.

Journal: Anaerobe 20070201

Title: Rapid and convenient detection of urinary equol by thin-layer chromatography.

Journal: Journal of nutritional science and vitaminology 20070201

Title: Equol producer status, salivary estradiol profile and urinary excretion of isoflavones in Irish Caucasian women, following ingestion of soymilk.

Journal: Steroids 20070101

Title: Effect of isolated isoflavone supplementation on ABCA1-dependent cholesterol efflux potential in postmenopausal women.

Journal: Menopause (New York, N.Y.) 20070101

Title: AVPV neurons containing estrogen receptor-beta in adult male rats are influenced by soy isoflavones.

Journal: BMC neuroscience 20070101

Title: Pilot study of urinary biomarkers of phytoestrogens, phthalates, and phenols in girls.

Journal: Environmental health perspectives 20070101

Title: Effects of dietary equol on body weight gain, intra-abdominal fat accumulation, plasma lipids, and glucose tolerance in ovariectomized Sprague-Dawley rats.

Journal: Menopause (New York, N.Y.) 20070101

Title: Possible role of equol status in the effects of isoflavone on bone and fat mass in postmenopausal Japanese women: a double-blind, randomized, controlled trial.

Journal: Menopause (New York, N.Y.) 20070101

Title: Review of the factors affecting bioavailability of soy isoflavones in humans.

Journal: Nutrition and cancer 20070101

Title: The effect of the phytoestrogens genistein, daidzein, and equol on the growth of tamoxifen-resistant T47D/PKC alpha.

Journal: Nutrition and cancer 20070101

Title: Soy isoflavones avert chronic inflammation-induced bone loss and vascular disease.

Journal: Journal of inflammation (London, England) 20070101

Title: Effect of protein source and resistance training on body composition and sex hormones.

Journal: Journal of the International Society of Sports Nutrition 20070101

Title: Isoflavones, equol and cardiovascular disease: pharmacological and therapeutic insights.

Journal: Current medicinal chemistry 20070101

Title: Intake of dietary phytoestrogen and indices of antioxidant and bone metabolism of pre- and post-menopausal Korean women.

Journal: Nutrition research and practice 20070101

Title: Occurrence of estrogenic compounds in and removal by a swine farm waste treatment plant.

Journal: Environmental science & technology 20061215

Title: Behavioral changes in fish exposed to phytoestrogens.

Journal: Environmental pollution (Barking, Essex : 1987) 20061201

Title: Molecular signatures of soy-derived phytochemicals in androgen-responsive prostate cancer cells: a comparison study using DNA microarray.

Journal: Molecular carcinogenesis 20061201

Title: Phyto- and endogenous estrogens differently activate intracellular calcium ion mobilization in bovine endometrial cells.

Journal: The Journal of reproduction and development 20061201

Title: Randomised, controlled, cross-over trial of soy protein with isoflavones on blood pressure and arterial function in hypertensive subjects.

Journal: Journal of the American College of Nutrition 20061201

Title: Total synthesis of (S)-equol.

Journal: Organic letters 20061123

Title: Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration.

Journal: The Journal of steroid biochemistry and molecular biology 20061101

Title: Associations among maternal soy intake, isoflavone levels in urine and blood samples, and maternal and umbilical hormone concentrations (Japan).

Journal: Cancer causes & control : CCC 20061101

Title: Phytoestrogens regulate transcription and translation of vitamin D receptor in colon cancer cells.

Journal: The Journal of endocrinology 20061101

Title: Consumption of Lactobacillus acidophilus and Bifidobacterium longum does not alter phytoestrogen metabolism and plasma hormones in men: a pilot study.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20061101

Title: [Progress in research of equol: a metabolite of the isoflavone daidzein].

Journal: Sheng li ke xue jin zhan [Progress in physiology] 20061001

Title: The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells.

Journal: The Journal of biological chemistry 20060915

Title: One-month exposure to soy isoflavones did not induce the ability to produce equol in postmenopausal women.

Journal: European journal of clinical nutrition 20060901

Title: Effects of high-dose soy isoflavones and equol on reproductive tissues in female cynomolgus monkeys.

Journal: Biology of reproduction 20060901

Title: Protective effect of the isoflavone equol against DNA damage induced by ultraviolet radiation to hairless mouse skin.

Journal: Journal of veterinary science 20060901

Title: Reduced isoflavone metabolites formed by the human gut microflora suppress growth but do not affect DNA integrity of human prostate cancer cells.

Journal: The British journal of nutrition 20060901

Title: Supplementation of difructose anhydride III enhanced elevation of plasma equol concentrations and lowered plasma total cholesterol in isoflavone-fed rats.

Journal: The British journal of nutrition 20060901

Title: Production of equol from daidzein by gram-positive rod-shaped bacterium isolated from rat intestine.

Journal: Journal of bioscience and bioengineering 20060901

Title: The prooxidant, rather than antioxidant, acts of daidzein in vivo and in vitro: daidzein suppresses glutathione metabolism.

Journal: European journal of pharmacology 20060807

Title: The effects of short-term oral phytoestrogen supplementation on the hypothalamic-pituitary-testicular axis in prostate cancer patients.

Journal: The Prostate 20060701

Title: Soya isoflavones suppress phorbol 12-myristate 13-acetate-induced COX-2 expression in MCF-7 cells.

Journal: The British journal of nutrition 20060701

Title: Concentrations of isoflavones in macaques consuming standard laboratory monkey diet.

Journal: Journal of the American Association for Laboratory Animal Science : JAALAS 20060701

Title: Concentrations of isoflavones in plasma and urine of post-menopausal women chronically ingesting high quantities of soy isoflavones.

Journal: Journal of pharmaceutical and biomedical analysis 20060607

Title: Dietary modulation of p-nonylphenol-induced polycystic kidneys in male Sprague-Dawley rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060601

Title: Assessing risks and benefits of genistein and soy.

Journal: Environmental health perspectives 20060601

Title: The science of soy: what do we really know?

Journal: Environmental health perspectives 20060601

Title: Validation and application of a robust yeast estrogen bioassay for the screening of estrogenic activity in animal feed.

Journal: Food additives and contaminants 20060601

Title: Effect of a nutritional supplementation on bone health in Chilean elderly subjects with femoral osteoporosis.

Journal: Journal of the American College of Nutrition 20060601

Title: Identification of equol producers in a Japanese population by high-performance liquid chromatography with coulometric array for determining serum isoflavones.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20060501

Title: Equol and para-ethyl-phenol stimulate prostaglandin F(2alpha) secretion in bovine corpus luteum: intracellular mechanisms of action.

Journal: Prostaglandins & other lipid mediators 20060501

Title: Antioxidant activity of isoflavones and their major metabolites using different in vitro assays.

Journal: Journal of agricultural and food chemistry 20060419

Title: Absorption of isoflavones in humans: effects of food matrix and processing.

Journal: The Journal of nutritional biochemistry 20060401

Title: Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro.

Journal: The Prostate 20060401

Title: Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice.

Journal: Carcinogenesis 20060401

Title: Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: a randomized placebo-controlled trial.

Journal: Metabolism: clinical and experimental 20060401

Title: Effects of phytoestrogens on testosterone secretion by Leydig cells from Biłgoraj ganders (Anser anser).

Journal: British poultry science 20060401

Title: Short-term phytoestrogen supplementation alters insulin-like growth factor profile but not lipid or antioxidant status.

Journal: The Journal of nutritional biochemistry 20060301

Title: Postmenopausal bone mineral density in relation to soy isoflavone-metabolizing phenotypes.

Journal: Maturitas 20060220

Title: Phytoestrogens and their metabolites inhibit the sensitivity of the bovine corpus luteum to luteotropic factors.

Journal: The Journal of reproduction and development 20060201

Title: Does genotype and equol-production status affect response to isoflavones? Data from a pan-European study on the effects of isoflavones on cardiovascular risk markers in post-menopausal women.

Journal: The Proceedings of the Nutrition Society 20060201

Title: Plasma and prostate phytoestrogen concentrations in prostate cancer patients after oral phytoestogen supplementation.

Journal: The Prostate 20060101

Title: Structural elucidation of hydroxylated metabolites of the isoflavan equol by gas chromatography-mass spectrometry and high-performance liquid chromatography-mass spectrometry.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060101

Title: Phyto-oestrogen intake in Scottish men: use of serum to validate a self-administered food-frequency questionnaire in older men.

Journal: European journal of clinical nutrition 20060101

Title: Isoflavonoid photoprotection in mouse and human skin is dependent on metallothionein.

Journal: The Journal of investigative dermatology 20060101

Title: Serum cholesterol efflux potential in postmenopausal women treated with isolated isoflavones.

Journal: Menopause (New York, N.Y.) 20060101

Title: Production of low-estrogen goldfish diet for in vivo endocrine disrupter test.

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20060101

Title: The effects of fructo-oligosaccharides in combination with soy protein on bone in osteopenic ovariectomized rats.

Journal: Menopause (New York, N.Y.) 20060101

Title: Genistein and 17beta-estradiol, but not equol, regulate vitamin D synthesis in human colon and breast cancer cells.

Journal: Anticancer research 20060101

Title: Equol: a comparison of the effects of the racemic compound with that of the purified S-enantiomer on the growth, invasion, and DNA integrity of breast and prostate cells in vitro.

Journal: Nutrition and cancer 20060101

Title: Soy isoflavones increase preprandial peptide YY (PYY), but have no effect on ghrelin and body weight in healthy postmenopausal women.

Journal: Journal of negative results in biomedicine 20060101

Title: An accurate and reproducible method for the quantitative analysis of isoflavones and their metabolites in rat plasma using liquid chromatography/mass spectrometry combined with photodiode array detection.

Journal: Journal of AOAC International 20060101

Title: Detection of isoflavones in mouse tibia after feeding daidzein.

Journal: Journal of medicinal food 20060101

Title: Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk.

Journal: Nutrition and cancer 20060101

Title: Phytoestrogen action in Leydig cells of Biłgoraj ganders (Anser anser).

Journal: Reproductive biology 20060101

Title: Estrogen receptor-independent inhibition of tumor necrosis factor-alpha gene expression by phytoestrogen equol is mediated by blocking nuclear factor-kappaB activation in mouse macrophages.

Journal: Biochemical pharmacology 20051219

Title: Circulating levels of isoflavones and markers of 5alpha-reductase activity are higher in Japanese compared with New Zealand males: what is the role of circulating steroids in prostate disease?

Journal: Steroids 20051215

Title: Isoflavones modulate the glucuronidation of estradiol in human liver microsomes.

Journal: Carcinogenesis 20051201

Title: Serum equol, bone mineral density and biomechanical bone strength differ among four mouse strains.

Journal: The Journal of nutritional biochemistry 20051201

Title: Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites.

Journal: Bioorganic & medicinal chemistry 20051201

Title: Phytoestrogen metabolites are much more active than phytoestrogens themselves in increasing prostaglandin F(2alpha) synthesis via prostaglanin F(2alpha) synthase-like 2 stimulation in bovine endometrium.

Journal: Prostaglandins & other lipid mediators 20051201

Title: Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production.

Journal: The American journal of clinical nutrition 20051201

Title: High concordance of daidzein-metabolizing phenotypes in individuals measured 1 to 3 years apart.

Journal: The British journal of nutrition 20051201

Title: Effect of pure genistein on bone markers and hot flushes.

Journal: Climacteric : the journal of the International Menopause Society 20051201

Title: Short-term soy and probiotic supplementation does not markedly affect concentrations of reproductive hormones in postmenopausal women with and without histories of breast cancer.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20051201

Title: Sensitive high-performance liquid chromatographic method using coulometric electrode array detection for measurement of phytoestrogens in dried blood spots.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105

Title: Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized BALB/c mice.

Journal: Journal of agricultural and food chemistry 20051102

Title: Urinary phytoestrogen concentrations in the U.S. population (1999-2000).

Journal: Journal of exposure analysis and environmental epidemiology 20051101

Title: Fetal exposure to phytoestrogens--the difference in phytoestrogen status between mother and fetus.

Journal: Environmental research 20051001

Title: Formononetin, a phyto-oestrogen, and its metabolites up-regulate interleukin-4 production in activated T cells via increased AP-1 DNA binding activity.

Journal: Immunology 20050901

Title: Phytoestrogens induce differential estrogen receptor alpha- or Beta-mediated responses in transfected breast cancer cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050901

Title: Estrogenic and genotoxic potential of equol and two hydroxylated metabolites of Daidzein in cultured human Ishikawa cells.

Journal: Toxicology letters 20050728

Title: Identification of urolithin a as a metabolite produced by human colon microflora from ellagic acid and related compounds.

Journal: Journal of agricultural and food chemistry 20050713

Title: Antipyretic, analgesic and muscle relaxant activities of pueraria isoflavonoids and their metabolites from Pueraria lobata Ohwi-a traditional Chinese drug.

Journal: Biological & pharmaceutical bulletin 20050701

Title: X-ray single-crystal analysis of (-)-(S)-equol isolated from rat's feces.

Journal: Chemistry & biodiversity 20050701

Title: Optimization of conditions for the enzymatic hydrolysis of phytoestrogen conjugates in urine and plasma.

Journal: Analytical biochemistry 20050615

Title: Experimental determination of octanol-water partition coefficients of quercetin and related flavonoids.

Journal: Journal of agricultural and food chemistry 20050601

Title: Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study.

Journal: Journal of epidemiology 20050601

Title: Phytoestrogens modulate prostaglandin production in bovine endometrium: cell type specificity and intracellular mechanisms.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050501

Title: Effect of consumption of soy isoflavones on behavioural, somatic and affective symptoms in women with premenstrual syndrome.

Journal: The British journal of nutrition 20050501

Title: Comparative study of oestrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20050401

Title: Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050301

Title: Soybean-derived phytoestrogens regulate prostaglandin secretion in endometrium during cattle estrous cycle and early pregnancy.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050301

Title: Protective effect of the isoflavonoid equol against hairless mouse skin carcinogenesis induced by UV radiation alone or with a chemical cocarcinogen.

Journal: Photochemistry and photobiology 20050101

Title: Isolation and characterisation of an equol-producing mixed microbial culture from a human faecal sample and its activity under gastrointestinal conditions.

Journal: Archives of microbiology 20050101

Title: Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050101

Title: Pharmacokinetics of isoflavones, daidzein and genistein, after ingestion of soy beverage compared with soy extract capsules in postmenopausal Thai women.

Journal: BMC clinical pharmacology 20050101

Title: Hypertensive crisis associated with high dose soy isoflavone supplementation in a post-menopausal woman: a case report [ISRCTN98074661].

Journal: BMC women's health 20050101

Title: Influences of dietary soy isoflavones on metabolism but not nociception and stress hormone responses in ovariectomized female rats.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Assessment of soy phytoestrogens' effects on bone turnover indicators in menopausal women with osteopenia in Iran: a before and after clinical trial.

Journal: Nutrition journal 20050101

Title: Characterization and quantification of soy isoflavone metabolites in serum of renal transplanted patients by high-performance liquid chromatography/electrospray ionization mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Alternative therapies for postmenopausal women.

Journal: International journal of fertility and women's medicine 20050101

Title: Effect of a soymilk supplement containing isoflavones on urinary F2 isoprostane levels in premenopausal women.

Journal: Nutrition and cancer 20050101

Title: Protection against photoaging in the hairless mouse by the isoflavone equol.

Journal: Photochemistry and photobiology 20050101

Title: Consumption of Lactobacillus acidophilus and Bifidobacterium longum do not alter urinary equol excretion and plasma reproductive hormones in premenopausal women.

Journal: European journal of clinical nutrition 20041201

Title: Lactobacillus gasseri: effects on mouse intestinal flora enzyme activity and isoflavonoids in the caecum and plasma.

Journal: The British journal of nutrition 20041101

Title: Familial correlations, segregation analysis, and nongenetic correlates of soy isoflavone-metabolizing phenotypes.

Journal: Experimental biology and medicine (Maywood, N.J.) 20041001

Title: Survey of estrogenic activity in fish feed by yeast estrogen-screen assay.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041001

Title: Automated online and off-line solid-phase extraction methods for measuring isoflavones and lignans in urine.

Journal: Journal of chromatographic science 20041001

Title: Biotransformation of soy isoflavone-glycosides in laying hens: intestinal absorption and preferential accumulation into egg yolk of equol, a more estrogenic metabolite of daidzein.

Journal: Biochimica et biophysica acta 20040924

Title: Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice.

Journal: Biology of reproduction 20040901

Title: Synthesis of phytoestrogenic isoflavonoid disulfates.

Journal: Steroids 20040901

Title: Daidzein together with high calcium preserve bone mass and biomechanical strength at multiple sites in ovariectomized mice.

Journal: Bone 20040801

Title: The need to decide if all estrogens are intrinsically similar.

Journal: Environmental health perspectives 20040801

Title: Blood isoflavone levels during intake of a controlled hospital diet.

Journal: Journal of nutritional science and vitaminology 20040801

Title: Growth performance, carcass characteristics and bioavailability of isoflavones in pigs fed soy bean based diets.

Journal: Archives of animal nutrition 20040801

Title: Circulating enterolactone and risk of breast cancer: a prospective study in New York.

Journal: British journal of cancer 20040705

Title: Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040701

Title: Mammographic density in relation to daidzein-metabolizing phenotypes in overweight, postmenopausal women.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040701

Title: Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry.

Journal: Journal of agricultural and food chemistry 20040616

Title: Genotoxicity of the isoflavones genistein, daidzein and equol in V79 cells.

Journal: Toxicology letters 20040615

Title: Inulin effects on bioavailability of soy isoflavones and their calcium absorption enhancing ability.

Journal: Journal of agricultural and food chemistry 20040519

Title: Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitro.

Journal: Cancer letters 20040510

Title: Highly elevated serum phyto-oestrogen concentrations in patients with diabetic nephropathy.

Journal: Journal of internal medicine 20040501

Title: Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids.

Journal: Obstetrics and gynecology 20040501

Title: Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040501

Title: Isoflavones stimulate estrogen receptor-mediated core histone acetylation.

Journal: Biochemical and biophysical research communications 20040423

Title: Equol is a novel anti-androgen that inhibits prostate growth and hormone feedback.

Journal: Biology of reproduction 20040401

Title: Urinary isoflavone kinetics: the effect of age, gender, food matrix and chemical composition.

Journal: The British journal of nutrition 20040401

Title: Influence of soya-based infant formula consumption on isoflavone and gut microflora metabolite concentrations in urine and on faecal microflora composition and metabolic activity in infants and children.

Journal: The British journal of nutrition 20040401

Title: Phytoestrogens are potent inhibitors of estrogen sulfation: implications for breast cancer risk and treatment.

Journal: The Journal of clinical endocrinology and metabolism 20040401

Title: Metabolism of daidzein by intestinal bacteria from rhesus monkeys (Macaca mulatta).

Journal: Comparative medicine 20040401

Title: Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-metabolizing phenotypes.

Journal: The Journal of steroid biochemistry and molecular biology 20040401

Title: Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta.

Journal: Bioorganic & medicinal chemistry 20040315

Title: Prediction of ligand binding affinity and orientation of xenoestrogens to the estrogen receptor by molecular dynamics simulations and the linear interaction energy method.

Journal: Journal of medicinal chemistry 20040212

Title: Comparisons of percent equol producers between prostate cancer patients and controls: case-controlled studies of isoflavones in Japanese, Korean and American residents.

Journal: Japanese journal of clinical oncology 20040201

Title: Effect of circulating forms of soy isoflavones on the oxidation of low density lipoprotein.

Journal: Free radical research 20040201

Title: Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County.

Journal: Carcinogenesis 20040101

Title: Limited lipid-lowering effects of regular consumption of whole soybean foods.

Journal: Annals of nutrition & metabolism 20040101

Title: Serum phytoestrogens and prostate cancer risk in a nested case-control study among Japanese men.

Journal: Cancer science 20040101

Title: Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection.

Journal: Bioscience, biotechnology, and biochemistry 20040101

Title: Phyto-oestrogens and breast cancer chemoprevention.

Journal: Breast cancer research : BCR 20040101

Title: Usefulness of the monkey model to investigate the role soy in postmenopausal women's health.

Journal: ILAR journal 20040101

Title: Behavioral effects of endocrine-disrupting substances: phytoestrogens.

Journal: ILAR journal 20040101

Title: Reports: plasma and dietary phytoestrogens and risk of premalignant lesions of the cervix.

Journal: Nutrition and cancer 20040101

Title: The topical isoflavonoid NV-07alpha reduces solar-simulated UV-induced suppression of Mantoux reactions in humans.

Journal: Photochemistry and photobiology 20040101

Title: Novel physiological function of fructooligosaccharides.

Journal: BioFactors (Oxford, England) 20040101

Title: Effects of isoflavone supplements on bone metabolic markers and climacteric symptoms in Japanese women.

Journal: BioFactors (Oxford, England) 20040101

Title: Isoflavones in several clover species and in milk from goats fed clovers.

Journal: BioFactors (Oxford, England) 20040101

Title: Measurement of isoflavones using liquid chromatography with multi-channel coulometric electrochemical detection.

Journal: BioFactors (Oxford, England) 20040101

Title: Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element.

Journal: Journal of agricultural and food chemistry 20031217

Title: Genotoxic activity of four metabolites of the soy isoflavone daidzein.

Journal: Mutation research 20031209

Title: Oestrogenic compounds and oxidative stress (in human sperm and lymphocytes in the Comet assay).

Journal: Mutation research 20031101

Title: A toxicity identification evaluation approach to studying estrogenic substances in hog manure and agricultural runoff.

Journal: Environmental toxicology and chemistry 20031001

Title: Antioxidant and free radical scavenging activity of isoflavone metabolites.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030901

Title: Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals.

Journal: Archives of microbiology 20030701

Title: Effects of the isoflavones genistein and equol on the gonadal development of Japanese medaka Oryzias latipes.

Journal: Environmental health perspectives 20030701

Title: Phytoestrogens: recent developments.

Journal: Planta medica 20030701

Title: Urinary and serum concentrations of seven phytoestrogens in a human reference population subset.

Journal: Journal of exposure analysis and environmental epidemiology 20030701

Title: Urinary equol excretion in relation to 2-hydroxyestrone and 16alpha-hydroxyestrone concentrations: an observational study of young to middle-aged women.

Journal: The Journal of steroid biochemistry and molecular biology 20030701

Title: Bioavailability of phyto-oestrogens.

Journal: The British journal of nutrition 20030601

Title: The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: an antioxidant mechanism for cell-mediated LDL modification.

Journal: Free radical biology & medicine 20030515

Title: Metabolism of isoflavones and lignans by the gut microflora: a study in germ-free and human flora associated rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030501

Title: Differential effects of natural and environmental estrogens on endothelin synthesis in bovine oviduct cells.

Journal: Biology of reproduction 20030401

Title: Quantification of isoflavones and lignans in urine using gas chromatography/mass spectrometry.

Journal: Analytical biochemistry 20030401

Title: Time-resolved fluoroimmunoassay for equol in plasma and urine.

Journal: The Journal of steroid biochemistry and molecular biology 20030401

Title: Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20030301

Title: Quantitation of soy-derived phytoestrogens in human breast tissue and biological fluids by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030125

Title: Soy isoflavonoid equol modulates the growth of benign and malignant prostatic epithelial cells in vitro.

Journal: The Prostate 20030101

Title: Identification of phytoestrogens in bovine milk using liquid chromatography/electrospray tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20030101

Title: Quantification of isoflavones and lignans in serum using isotope dilution liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20030101

Title: Effect of in utero-administered coumestrol, equol, and organic selenium on biomarkers for phase 2 enzyme capacity and redox status.

Journal: Nutrition and cancer 20030101

Title: Higher consumption of green tea may enhance equol production.

Journal: Asian Pacific journal of cancer prevention : APJCP 20030101

Title: High-throughput quantification of soy isoflavones in human and rodent blood using liquid chromatography with electrospray mass spectrometry and tandem mass spectrometry detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020925

Title: Time-resolved fluoroimmunoassay of plasma and urine O-desmethylangolensin.

Journal: The Journal of steroid biochemistry and molecular biology 20020801

Title: Is daidzein non-metabolizer a high risk for prostate cancer? A case-controlled study of serum soybean isoflavone concentration.

Journal: Japanese journal of clinical oncology 20020801

Title: Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons.

Journal: Experimental biology and medicine (Maywood, N.J.) 20020701

Title: Effects of rice starch-isoflavone diet or potato starch-isoflavone diet on plasma isoflavone, plasma lipids, cecal enzyme activity, and composition of fecal microflora in adult mice.

Journal: Journal of nutritional science and vitaminology 20020601

Title: Comparative study of concentration of isoflavones and lignans in plasma and prostatic tissues of normal control and benign prostatic hyperplasia.

Journal: Yonsei medical journal 20020401

Title: Overnight urinary isoflavone excretion in a population of women living in the United States, and its relationship to isoflavone intake.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020301

Title: Effects of dietary phytoestrogens in vivo and in vitro in rainbow trout and Siberian sturgeon: interests and limits of the in vitro studies of interspecies differences.

Journal: General and comparative endocrinology 20020301

Title: The correlation between dietary soy phytoestrogens and neuropathic pain behavior in rats after partial denervation.

Journal: Anesthesia and analgesia 20020201

Title: Daidzein: bioavailability, potential for reproductive toxicity, and breast cancer chemoprevention in female rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020201

Title: Anticarcinogenic effects of isoflavones may be mediated by genistein in mouse mammary tumor virus-induced breast cancer.

Journal: Oncology 20020101

Title: In vitro isoflavone supplementation reduces hydrogen peroxide-induced DNA damage in sperm.

Journal: Teratogenesis, carcinogenesis, and mutagenesis 20020101

Title: Quantitative analysis of urinary daidzein and equol by gas chromatography after solid-phase extraction and high-performance liquid chromatography.

Journal: The International journal of biological markers 20020101

Title: Effects of phytoestrogens on DNA synthesis and creatine kinase activity in vascular cells.

Journal: American journal of hypertension 20011201

Title: Dietary soy phytoestrogen effects on brain structure and aromatase in Long-Evans rats.

Journal: Neuroreport 20011116

Title: Urinary metabolites of genistein administered orally to rats.

Journal: Chemical & pharmaceutical bulletin 20011101

Title: Regulation of phenobarbital-mediated induction of CYP102 (cytochrome P450(BM-3)) in Bacillus megaterium by phytochemicals from soy and green tea.

Journal: Journal of agricultural and food chemistry 20011001

Title: Isoflavonoid compounds from red clover (Trifolium pratense) protect from inflammation and immune suppression induced by UV radiation.

Journal: Photochemistry and photobiology 20010901

Title: Disposition and biotransformation of the estrogenic isoflavone daidzein in rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010801

Title: The vascular activity of some isoflavone metabolites: implications for a cardioprotective role.

Journal: British journal of pharmacology 20010601

Title: Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones.

Journal: Laboratory investigation; a journal of technical methods and pathology 20010501

Title: Interaction of phytoestrogens with estrogen receptors alpha and beta.

Journal: Biological & pharmaceutical bulletin 20010401

Title: Effect of phytoestrogen and antioxidant supplementation on oxidative DNA damage assessed using the comet assay.

Journal: Mutation research 20010307

Title: Assaying the estrogenicity of phytoestrogens in cells of different estrogen sensitive tissues.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20010101

Title: Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens.

Journal: BMC neuroscience 20010101

Title: Axelson M, et al. The identification of the weak oestrogen equol -hydroxy-3-(4'-hydroxyphenyl)chroman in human urine. Biochem J. 1982 Feb 1;201(2):353-7.

Title: Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81(5):1072-9. human intestinal bacterial flora.

Title: Wang J, et al. Equol promotes rat osteoblast proliferation and differentiation through activating estrogen receptor. Genet Mol Res. 2014 Jul 4;13(3):5055-63.

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Tags:94105-90-5 Molecular Formula|94105-90-5 MDL|94105-90-5 SMILES|94105-90-5 Equol |Heterocyclic_Building_Blocks