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942398-84-7,MFCD30489749
Catalog No.:AA00GU8A

942398-84-7 | Amiselimod hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$29.00   $21.00
- +
5mg
98%
in stock  
$74.00   $52.00
- +
10mg
98%
in stock  
$110.00   $77.00
- +
25mg
98%
in stock  
$185.00   $130.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00GU8A
Chemical Name:
Amiselimod hydrochloride
CAS Number:
942398-84-7
Molecular Formula:
C19H31ClF3NO3
Molecular Weight:
413.9025
MDL Number:
MFCD30489749
SMILES:
CCCCCCCOc1ccc(cc1C(F)(F)F)CCC(CO)(CO)N.Cl
Properties
Computed Properties
 
Complexity:
376  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
12  

Downstream Synthesis Route

[1]Patent:EP1961734,2008,A1.Locationinpatent:Page/Pagecolumn36

[1]Patent:EP1961734,2008,A1.Locationinpatent:Page/Pagecolumn35

[1]Patent:EP1961734,2008,A1.Locationinpatent:Page/Pagecolumn64

[1]Patent:EP1961734,2008,A1.Locationinpatent:Page/Pagecolumn35

[1]Patent:US2019/161432,2019,A1.Locationinpatent:Paragraph0083;0092;0093

Literature

Title: Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk.

Journal: British journal of pharmacology 20170101

Title: Sugahara K et al. Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk. Br J Pharmacol. 2016 Oct 7.

Title: Kappos L et al. Safety and efficacy of amiselimod in relapsing multiple sclerosis (MOMENTUM): a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Neurol. 2016 Oct;15(11):1148-59.

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SDS
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